| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Cloxacillin (sodium) perturbation in H4 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Cloxacillin (sodium)_H4 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.222559 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0679686 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0620346 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0590245 |
| VEGFA | vascular endothelial growth factor A | 0.0558853 |
| FAM13A | family with sequence similarity 13, member A | 0.0484936 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.047758 |
| FAM219A | family with sequence similarity 219, member A | 0.0464763 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0431439 |
| SRP54 | signal recognition particle 54kDa | 0.0416547 |
| SUCO | SUN domain containing ossification factor | 0.03925 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0356929 |
| GOLGB1 | golgin B1 | 0.0336929 |
| XKR6 | XK, Kell blood group complex subunit-related family, member 6 | 0.0334957 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0331407 |
| C1S | complement component 1, s subcomponent | 0.0292592 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.028747 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0287134 |
| RUNX1 | runt-related transcription factor 1 | 0.0276043 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0270585 |
| SND1 | staphylococcal nuclease and tudor domain containing 1 | 0.0267833 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0259854 |
| ZNF841 | zinc finger protein 841 | 0.0256642 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0255048 |
| OXR1 | oxidation resistance 1 | 0.0252633 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | 0.0251735 |
| DTNA | dystrobrevin, alpha | 0.0245929 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0245283 |
| COPA | coatomer protein complex, subunit alpha | 0.0245222 |
| ADM | adrenomedullin | 0.024486 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0244043 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | 0.0242085 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.024187 |
| INSIG2 | insulin induced gene 2 | 0.0240561 |
| PGM3 | phosphoglucomutase 3 | 0.0240357 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0239393 |
| MAP3K13 | mitogen-activated protein kinase kinase kinase 13 | 0.0237577 |
| TMF1 | TATA element modulatory factor 1 | 0.0236886 |
| HELZ | helicase with zinc finger | 0.023649 |
| FNIP1 | folliculin interacting protein 1 | 0.0232835 |
| MLEC | malectin | 0.0231554 |
| SFTPA2 | surfactant protein A2 | 0.0227532 |
| NRXN3 | neurexin 3 | 0.022659 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0225095 |
| IGFBP5 | insulin-like growth factor binding protein 5 | 0.0223378 |
| PIAS2 | protein inhibitor of activated STAT, 2 | 0.0221636 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0221232 |
| COG6 | component of oligomeric golgi complex 6 | 0.0220553 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | 0.0217595 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0215754 |
| SUPT5H | suppressor of Ty 5 homolog (S. cerevisiae) | 0.0211812 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0209502 |
| ITGB3BP | integrin beta 3 binding protein (beta3-endonexin) | 0.0208945 |
| DGKI | diacylglycerol kinase, iota | 0.020574 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0196803 |
| TTC17 | tetratricopeptide repeat domain 17 | 0.0194266 |
| GOLGA4 | golgin A4 | 0.0194109 |
| NBAS | neuroblastoma amplified sequence | 0.0193901 |
| KDM5B | lysine (K)-specific demethylase 5B | 0.0193821 |
| ZBTB1 | zinc finger and BTB domain containing 1 | 0.0193812 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0193704 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0190563 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0189829 |
| ARHGAP22 | Rho GTPase activating protein 22 | 0.0189621 |
| TP53BP1 | tumor protein p53 binding protein 1 | 0.0189234 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | 0.0183999 |
| RAB3GAP1 | RAB3 GTPase activating protein subunit 1 (catalytic) | 0.0180744 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | 0.0180175 |
| LRRTM4 | leucine rich repeat transmembrane neuronal 4 | 0.0178046 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0177193 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | 0.0177164 |
| CFAP96 | cilia and flagella associated protein 96 | 0.017699 |
| SETD5 | SET domain containing 5 | 0.0176128 |
| NUDCD3 | NudC domain containing 3 | 0.0176113 |
| MOCOS | molybdenum cofactor sulfurase | 0.0175052 |
| PDXK | pyridoxal (pyridoxine, vitamin B6) kinase | 0.0174244 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) | 0.0173423 |
| PCBP2 | poly(rC) binding protein 2 | 0.0170714 |
| YAP1 | Yes-associated protein 1 | 0.0169802 |
| LINGO2 | leucine rich repeat and Ig domain containing 2 | 0.0169556 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0169132 |
| GYS1 | glycogen synthase 1 (muscle) | 0.0168663 |
| GDF15 | growth differentiation factor 15 | 0.0168268 |
| ARHGAP32 | Rho GTPase activating protein 32 | 0.0165533 |
| SLC41A2 | solute carrier family 41 (magnesium transporter), member 2 | 0.0165037 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0164976 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0164756 |
| SEPTIN9 | septin 9 | 0.0163373 |
| MMP12 | matrix metallopeptidase 12 | 0.0160485 |
| ARFGEF1 | ADP-ribosylation factor guanine nucleotide-exchange factor 1 (brefeldin A-inhibited) | 0.016003 |
| MCL1 | myeloid cell leukemia 1 | 0.0158492 |
| POM121C | POM121 transmembrane nucleoporin C | 0.0156434 |
| MTR | 5-methyltetrahydrofolate-homocysteine methyltransferase | 0.0154772 |
| USP36 | ubiquitin specific peptidase 36 | 0.015474 |
| EYA1 | EYA transcriptional coactivator and phosphatase 1 | 0.0153544 |
| SPTY2D1 | SPT2, Suppressor of Ty, domain containing 1 (S. cerevisiae) | 0.015319 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0151435 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0149991 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0149948 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0149298 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.244833 |
| VIM | vimentin | -0.127652 |
| CD44 | CD44 molecule (Indian blood group) | -0.096358 |
| FN1 | fibronectin 1 | -0.0953724 |
| COL6A3 | collagen, type VI, alpha 3 | -0.0863536 |
| TMSB10 | thymosin beta 10 | -0.0832541 |
| LDHA | lactate dehydrogenase A | -0.0816818 |
| MAP1B | microtubule-associated protein 1B | -0.0787351 |
| DST | dystonin | -0.0786371 |
| MT2A | metallothionein 2A | -0.0748752 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0729577 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0714655 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0689002 |
| ANXA2 | annexin A2 | -0.0681235 |
| NDRG1 | N-myc downstream regulated 1 | -0.0668992 |
| SBF2 | SET binding factor 2 | -0.0624064 |
| NAV3 | neuron navigator 3 | -0.0622004 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0591648 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0581828 |
| TNNC1 | troponin C type 1 (slow) | -0.0565862 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0525215 |
| OSMR | oncostatin M receptor | -0.0518095 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0512293 |
| EGFR | epidermal growth factor receptor | -0.050377 |
| RTN4 | reticulon 4 | -0.049312 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0489296 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0481507 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0477357 |
| STC1 | stanniocalcin 1 | -0.045582 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0447245 |
| ASPH | aspartate beta-hydroxylase | -0.0436855 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0420325 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.0407505 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0402739 |
| STK17A | serine/threonine kinase 17a | -0.039747 |
| SPAG9 | sperm associated antigen 9 | -0.0390923 |
| GLIS3 | GLIS family zinc finger 3 | -0.0387736 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0385681 |
| PGK1 | phosphoglycerate kinase 1 | -0.0385514 |
| ACTN4 | actinin, alpha 4 | -0.0385028 |
| FTL | ferritin, light polypeptide | -0.0382679 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0375706 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.037041 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0368486 |
| ENO1 | enolase 1, (alpha) | -0.0357796 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0352711 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0351235 |
| ANLN | anillin, actin binding protein | -0.0344044 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0343372 |
| TPI1 | triosephosphate isomerase 1 | -0.0338611 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0338315 |
| SAMD9 | sterile alpha motif domain containing 9 | -0.0338089 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0332883 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.0331765 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0331436 |
| LOX | lysyl oxidase | -0.0330191 |
| VCL | vinculin | -0.0328212 |
| TPM4 | tropomyosin 4 | -0.0324697 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0318144 |
| EGR1 | early growth response 1 | -0.0315299 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0303123 |
| KYNU | kynureninase | -0.0301438 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0299181 |
| FBXL17 | F-box and leucine-rich repeat protein 17 | -0.0296676 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | -0.0295333 |
| TENM3 | teneurin transmembrane protein 3 | -0.0290658 |
| PLAUR | plasminogen activator, urokinase receptor | -0.0290249 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0290135 |
| INHBA | inhibin, beta A | -0.0288872 |
| TXNRD1 | thioredoxin reductase 1 | -0.0286911 |
| RPS24 | ribosomal protein S24 | -0.0286305 |
| RIGI | RNA sensor RIG-I | -0.0283089 |
| DIAPH3 | diaphanous-related formin 3 | -0.0280813 |
| PLCB4 | phospholipase C, beta 4 | -0.0273231 |
| TNS3 | tensin 3 | -0.0270902 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | -0.0256928 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | -0.0256373 |
| CDK6 | cyclin-dependent kinase 6 | -0.0255921 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | -0.025467 |
| FER | fer (fps/fes related) tyrosine kinase | -0.0249817 |
| EMP1 | epithelial membrane protein 1 | -0.0248762 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0247148 |
| HIBADH | 3-hydroxyisobutyrate dehydrogenase | -0.0247101 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0246394 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0244347 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0242839 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.024232 |
| SERPINH1 | serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1) | -0.0241287 |
| NF1 | neurofibromin 1 | -0.0239015 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0235162 |
| PARVA | parvin, alpha | -0.023505 |
| KLF6 | Kruppel-like factor 6 | -0.0233424 |
| LRRC49 | leucine rich repeat containing 49 | -0.0232024 |
| TMSB4X | thymosin beta 4, X-linked | -0.0230469 |
| SDC4 | syndecan 4 | -0.0229339 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | -0.0229052 |
| TPTE | transmembrane phosphatase with tensin homology | -0.0225717 |
| NAALADL2 | N-acetylated alpha-linked acidic dipeptidase-like 2 | -0.0225661 |
| RFX8 | RFX family member 8, lacking RFX DNA binding domain | -0.0225476 |
| NEDD4 | neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase | -0.0225323 |
