| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Cloxacillin (sodium) perturbation in HCT15 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Cloxacillin (sodium)_HCT15 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NDRG1 | N-myc downstream regulated 1 | 0.177524 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.115183 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.113452 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0960272 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.080842 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0751259 |
| PLAUR | plasminogen activator, urokinase receptor | 0.0645233 |
| AHNAK | AHNAK nucleoprotein | 0.0645114 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0637208 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0614567 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0516801 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0507755 |
| OGA | O-GlcNAcase | 0.0489376 |
| PGK1 | phosphoglycerate kinase 1 | 0.0482612 |
| ENO1 | enolase 1, (alpha) | 0.0476651 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0472939 |
| FAM117B | family with sequence similarity 117, member B | 0.0466402 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0456121 |
| PRELID2 | PRELI domain containing 2 | 0.0436996 |
| ZNF292 | zinc finger protein 292 | 0.0415738 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0400261 |
| TXNIP | thioredoxin interacting protein | 0.0387634 |
| RNF24 | ring finger protein 24 | 0.0386836 |
| TNKS | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase | 0.0380056 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0375133 |
| RIOK3 | RIO kinase 3 | 0.0363045 |
| PFKFB3 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 | 0.0362983 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | 0.03629 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0359634 |
| RLF | rearranged L-myc fusion | 0.0351883 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0347061 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0342111 |
| YEATS2 | YEATS domain containing 2 | 0.0339825 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | 0.0330825 |
| DSPP | dentin sialophosphoprotein | 0.0328794 |
| INSIG2 | insulin induced gene 2 | 0.0317286 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0311082 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0306152 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.030474 |
| GOLGA4 | golgin A4 | 0.0297692 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.029748 |
| ZNF638 | zinc finger protein 638 | 0.0297278 |
| RNMT | RNA (guanine-7-) methyltransferase | 0.0296606 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0292473 |
| SUCO | SUN domain containing ossification factor | 0.0290885 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0280056 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) | 0.0278435 |
| KDM7A | lysine (K)-specific demethylase 7A | 0.0278366 |
| TMF1 | TATA element modulatory factor 1 | 0.0277696 |
| SFXN1 | sideroflexin 1 | 0.0277671 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | 0.0276423 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | 0.0262956 |
| TAC4 | tachykinin 4 (hemokinin) | 0.0261789 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0259763 |
| ACBD3 | acyl-CoA binding domain containing 3 | 0.0258767 |
| CANX | calnexin | 0.02586 |
| SDC4 | syndecan 4 | 0.0254898 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | 0.025174 |
| USP9Y | ubiquitin specific peptidase 9, Y-linked | 0.0247764 |
| SRP54 | signal recognition particle 54kDa | 0.0245412 |
| WWC2 | WW and C2 domain containing 2 | 0.0244819 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0242891 |
| TBC1D22A | TBC1 domain family, member 22A | 0.0238271 |
| CORO1C | coronin, actin binding protein, 1C | 0.0237614 |
| LMAN1 | lectin, mannose-binding, 1 | 0.0236667 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0231668 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0222259 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | 0.0220833 |
| ZNF654 | zinc finger protein 654 | 0.0219964 |
| ARRDC3 | arrestin domain containing 3 | 0.0217489 |
| OXSR1 | oxidative stress responsive 1 | 0.0214272 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0211865 |
| ANGPTL4 | angiopoietin-like 4 | 0.0211674 |
| RPL3 | ribosomal protein L3 | 0.0210745 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.0200739 |
| MIMS1 | mitochondrial inner membrane scaffold 1 | 0.0200709 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0199734 |
| AVL9 | AVL9 homolog (S. cerevisiase) | 0.019707 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.0194101 |
| PHF21A | PHD finger protein 21A | 0.0193147 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0191892 |
| UBA2 | ubiquitin-like modifier activating enzyme 2 | 0.0191383 |
| UBXN7 | UBX domain protein 7 | 0.0186376 |
| PLEKHA2 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 2 | 0.0185993 |
| RBM26 | RNA binding motif protein 26 | 0.0182709 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0182421 |
| ARL5B | ADP-ribosylation factor-like 5B | 0.0181718 |
| PCM1 | pericentriolar material 1 | 0.0181388 |
| PDK3 | pyruvate dehydrogenase kinase, isozyme 3 | 0.0181019 |
| HIPK3 | homeodomain interacting protein kinase 3 | 0.018093 |
| USP37 | ubiquitin specific peptidase 37 | 0.018064 |
| POM121 | POM121 transmembrane nucleoporin | 0.0180066 |
| CDK19 | cyclin-dependent kinase 19 | 0.017984 |
| FUT11 | fucosyltransferase 11 (alpha (1,3) fucosyltransferase) | 0.0179533 |
| BRD2 | bromodomain containing 2 | 0.017808 |
| XRN1 | 5'-3' exoribonuclease 1 | 0.0176963 |
| MORF4L2 | mortality factor 4 like 2 | 0.0176367 |
| PPP1R13L | protein phosphatase 1, regulatory subunit 13 like | 0.0175836 |
| EPN2 | epsin 2 | 0.0172766 |
| TNFRSF10D | tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain | 0.0171812 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.223278 |
| PTMA | prothymosin, alpha | -0.184755 |
| TMSB10 | thymosin beta 10 | -0.157579 |
| FAT1 | FAT atypical cadherin 1 | -0.120925 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.108544 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.073859 |
| VCL | vinculin | -0.0736341 |
| INTS6 | integrator complex subunit 6 | -0.0724049 |
| RPL35A | ribosomal protein L35a | -0.0721897 |
| EGR1 | early growth response 1 | -0.0696632 |
| POTEF | POTE ankyrin domain family, member F | -0.0575252 |
| S100A9 | S100 calcium binding protein A9 | -0.0536544 |
| RPLP1 | ribosomal protein, large, P1 | -0.052313 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0500164 |
| ANKRD17 | ankyrin repeat domain 17 | -0.0491825 |
| ACTG1 | actin gamma 1 | -0.0489008 |
| RPLP2 | ribosomal protein, large, P2 | -0.048467 |
| PKM | pyruvate kinase, muscle | -0.0477935 |
| TENM3 | teneurin transmembrane protein 3 | -0.0469955 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0462282 |
| HMGA1 | high mobility group AT-hook 1 | -0.0456769 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0446629 |
| RPS6 | ribosomal protein S6 | -0.044613 |
| TUBA1B | tubulin, alpha 1b | -0.0444949 |
| RPL23 | ribosomal protein L23 | -0.044117 |
| HMGA2 | high mobility group AT-hook 2 | -0.0434772 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0433296 |
| RAD51B | RAD51 paralog B | -0.0425115 |
| RPS8 | ribosomal protein S8 | -0.0421262 |
| RPS21 | ribosomal protein S21 | -0.0417017 |
| CENPF | centromere protein F, 350/400kDa | -0.0411784 |
| RPS19 | ribosomal protein S19 | -0.040563 |
| PFN1 | profilin 1 | -0.039784 |
| RPL5 | ribosomal protein L5 | -0.0396131 |
| WWOX | WW domain containing oxidoreductase | -0.0392232 |
| FAF1 | Fas (TNFRSF6) associated factor 1 | -0.0384912 |
| CCND1 | cyclin D1 | -0.0381976 |
| RPL34 | ribosomal protein L34 | -0.0377983 |
| MSI2 | musashi RNA-binding protein 2 | -0.0377224 |
| FHIT | fragile histidine triad | -0.0375472 |
| CBX3 | chromobox homolog 3 | -0.0372046 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0365628 |
| HMGB1 | high mobility group box 1 | -0.036241 |
| EIF5B | eukaryotic translation initiation factor 5B | -0.0361867 |
| RPS24 | ribosomal protein S24 | -0.0359559 |
| MT2A | metallothionein 2A | -0.0356064 |
| TPI1 | triosephosphate isomerase 1 | -0.0354791 |
| KRT18 | keratin 18, type I | -0.0346627 |
| CADPS | Ca++-dependent secretion activator | -0.0342785 |
| RPL31 | ribosomal protein L31 | -0.0338494 |
| FBXO11 | F-box protein 11 | -0.0337572 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.033617 |
| PA2G4 | proliferation-associated 2G4, 38kDa | -0.0332728 |
| RPL19 | ribosomal protein L19 | -0.0331897 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0329264 |
| RPS23 | ribosomal protein S23 | -0.0327408 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0327363 |
| MCL1 | myeloid cell leukemia 1 | -0.0325583 |
| RPS15 | ribosomal protein S15 | -0.0322549 |
| SERBP1 | SERPINE1 mRNA binding protein 1 | -0.0321965 |
| RPL26 | ribosomal protein L26 | -0.0321143 |
| SON | SON DNA binding protein | -0.0318963 |
| RPL37A | ribosomal protein L37a | -0.0318671 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0317723 |
| RPS25 | ribosomal protein S25 | -0.0316653 |
| SPIDR | scaffolding protein involved in DNA repair | -0.0316372 |
| LARP1B | La ribonucleoprotein domain family, member 1B | -0.0315393 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | -0.0314772 |
| ATP1B3 | ATPase, Na+/K+ transporting, beta 3 polypeptide | -0.0313247 |
| TPM4 | tropomyosin 4 | -0.0313078 |
| FRAS1 | Fraser extracellular matrix complex subunit 1 | -0.0312293 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0309465 |
| RPL18 | ribosomal protein L18 | -0.0304282 |
| MKI67 | marker of proliferation Ki-67 | -0.0303527 |
| HNRNPD | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) | -0.0303172 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0302163 |
| RPS11 | ribosomal protein S11 | -0.0300947 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | -0.0297702 |
| PABPN1 | poly(A) binding protein, nuclear 1 | -0.0297536 |
| BAZ1B | bromodomain adjacent to zinc finger domain, 1B | -0.0296353 |
| DDX46 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 | -0.0295965 |
| RPL27A | ribosomal protein L27a | -0.029589 |
| VTI1A | vesicle transport through interaction with t-SNAREs 1A | -0.029546 |
| RPL12 | ribosomal protein L12 | -0.0292328 |
| NASP | nuclear autoantigenic sperm protein (histone-binding) | -0.0292253 |
| RPL11 | ribosomal protein L11 | -0.0290324 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0290013 |
| ZNRF3 | zinc and ring finger 3 | -0.0287606 |
| RPL32 | ribosomal protein L32 | -0.0284429 |
| RPS29 | ribosomal protein S29 | -0.0283378 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0282449 |
| FUS | FUS RNA binding protein | -0.0277729 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0277018 |
| RPLP0 | ribosomal protein, large, P0 | -0.0276921 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | -0.0275691 |
| FRMD5 | FERM domain containing 5 | -0.0272072 |
| SMARCA4 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 | -0.0271711 |
| MORC4 | MORC family CW-type zinc finger 4 | -0.02694 |
| DIAPH2 | diaphanous-related formin 2 | -0.0267749 |
| SMARCC1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 | -0.0266766 |
