| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Cloxacillin (sodium) perturbation in HEC-1-A cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Cloxacillin (sodium)_HEC-1-A drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.197665 |
| GOLGA4 | golgin A4 | 0.116705 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0980948 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0907762 |
| CANX | calnexin | 0.0905724 |
| APP | amyloid beta (A4) precursor protein | 0.0869835 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0863026 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0828234 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0826247 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0794744 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0793866 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0783024 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0774072 |
| ENO1 | enolase 1, (alpha) | 0.0770313 |
| ZNF292 | zinc finger protein 292 | 0.0738406 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0699116 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0693998 |
| HELZ | helicase with zinc finger | 0.0688658 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0620533 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0615891 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0589913 |
| TPM4 | tropomyosin 4 | 0.058243 |
| ANXA2 | annexin A2 | 0.0579506 |
| SET | SET nuclear proto-oncogene | 0.0576681 |
| GOLGB1 | golgin B1 | 0.0575586 |
| JMJD1C | jumonji domain containing 1C | 0.0567121 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0563808 |
| YBX1 | Y box binding protein 1 | 0.0548804 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0547029 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.052147 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0511416 |
| CALR | calreticulin | 0.0508408 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0503084 |
| TPM3 | tropomyosin 3 | 0.0496498 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0492231 |
| RPL3 | ribosomal protein L3 | 0.0482702 |
| ANXA1 | annexin A1 | 0.0474737 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0472074 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0471039 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0468167 |
| PKM | pyruvate kinase, muscle | 0.0454635 |
| DSG2 | desmoglein 2 | 0.0449869 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0449213 |
| TMF1 | TATA element modulatory factor 1 | 0.0447075 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0427363 |
| POTEF | POTE ankyrin domain family, member F | 0.0426438 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0411978 |
| DSPP | dentin sialophosphoprotein | 0.0411604 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.0403905 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0403394 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0401923 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0397677 |
| EZR | ezrin | 0.0393241 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0391595 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0386888 |
| RPS2 | ribosomal protein S2 | 0.038339 |
| MATR3 | matrin 3 | 0.0382017 |
| VMP1 | vacuole membrane protein 1 | 0.0375648 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0375232 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0368779 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.036867 |
| YEATS2 | YEATS domain containing 2 | 0.0365951 |
| SBF2 | SET binding factor 2 | 0.0365799 |
| RPS6 | ribosomal protein S6 | 0.0365765 |
| LAMB3 | laminin, beta 3 | 0.0359874 |
| SPAG9 | sperm associated antigen 9 | 0.0358162 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.0356481 |
| FNIP1 | folliculin interacting protein 1 | 0.0356285 |
| SUPT5H | suppressor of Ty 5 homolog (S. cerevisiae) | 0.0351196 |
| LMAN1 | lectin, mannose-binding, 1 | 0.0349984 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0346126 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0345805 |
| TFG | TRK-fused gene | 0.0344787 |
| ARF4 | ADP-ribosylation factor 4 | 0.0343025 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0342857 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0342509 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0341973 |
| COPA | coatomer protein complex, subunit alpha | 0.0335149 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0332888 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0326737 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0326023 |
| BRD2 | bromodomain containing 2 | 0.032576 |
| TPD52 | tumor protein D52 | 0.03248 |
| ARFGEF3 | ARFGEF family member 3 | 0.0320432 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0317629 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0317065 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0316497 |
| SLMAP | sarcolemma associated protein | 0.0316298 |
| FNBP1L | formin binding protein 1-like | 0.0315954 |
| ZNF148 | zinc finger protein 148 | 0.0314646 |
| SMAD3 | SMAD family member 3 | 0.0314018 |
| CCNL1 | cyclin L1 | 0.0310874 |
| ANKRD36 | ankyrin repeat domain 36 | 0.0310298 |
| SEC24A | SEC24 family member A | 0.0309694 |
| RIOK3 | RIO kinase 3 | 0.0309348 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0303621 |
| RNF145 | ring finger protein 145 | 0.0303391 |
| RYBP | RING1 and YY1 binding protein | 0.0301247 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0300921 |
| SEC24D | SEC24 family member D | 0.0300888 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TMSB10 | thymosin beta 10 | -0.153794 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.111178 |
| MT2A | metallothionein 2A | -0.100802 |
| RHEX | regulator of hemoglobinization and erythroid cell expansion | -0.0981502 |
| RPL35A | ribosomal protein L35a | -0.0721673 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0694817 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0614181 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0564315 |
| RPS19 | ribosomal protein S19 | -0.0542428 |
| HMGA2 | high mobility group AT-hook 2 | -0.0538672 |
| WWOX | WW domain containing oxidoreductase | -0.0535594 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | -0.0515486 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0482453 |
| PRELID2 | PRELI domain containing 2 | -0.0454458 |
| RAD51B | RAD51 paralog B | -0.0452372 |
| DLC1 | DLC1 Rho GTPase activating protein | -0.0452232 |
| RPL31 | ribosomal protein L31 | -0.0450532 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | -0.0442769 |
| RPL32 | ribosomal protein L32 | -0.04391 |
| RPL23 | ribosomal protein L23 | -0.0435307 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.04303 |
| DSCAML1 | Down syndrome cell adhesion molecule like 1 | -0.0424172 |
| RFC3 | replication factor C (activator 1) 3, 38kDa | -0.0422699 |
| RPLP2 | ribosomal protein, large, P2 | -0.0422516 |
| FHIT | fragile histidine triad | -0.0401371 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0401186 |
| ATG7 | autophagy related 7 | -0.0395672 |
| RPS24 | ribosomal protein S24 | -0.0393812 |
| MT1X | metallothionein 1X | -0.0376144 |
| FLNA | filamin A, alpha | -0.035307 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0351119 |
| RPLP1 | ribosomal protein, large, P1 | -0.0349815 |
| PCED1B | PC-esterase domain containing 1B | -0.0330842 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0321708 |
| RPL9 | ribosomal protein L9 | -0.0319738 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -0.0315657 |
| ADAMTS9 | ADAM metallopeptidase with thrombospondin type 1 motif, 9 | -0.0311675 |
| NSD2 | nuclear receptor binding SET domain protein 2 | -0.0310862 |
| TUBB4B | tubulin, beta 4B class IVb | -0.03096 |
| RPS21 | ribosomal protein S21 | -0.0308805 |
| ACTG1 | actin gamma 1 | -0.0305072 |
| DEK | DEK proto-oncogene | -0.0301719 |
| HMGB1 | high mobility group box 1 | -0.0300049 |
| KAZN | kazrin, periplakin interacting protein | -0.0291874 |
| MACROD2 | MACRO domain containing 2 | -0.0287703 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0285542 |
| RPL34 | ribosomal protein L34 | -0.0282359 |
| AEBP2 | AE binding protein 2 | -0.0281032 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0279789 |
| KLF6 | Kruppel-like factor 6 | -0.0277832 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0271937 |
| DIAPH3 | diaphanous-related formin 3 | -0.0269224 |
| RPL35 | ribosomal protein L35 | -0.0265926 |
| S100A10 | S100 calcium binding protein A10 | -0.0265294 |
| SCLT1 | sodium channel and clathrin linker 1 | -0.0264297 |
| RPL36 | ribosomal protein L36 | -0.0263597 |
| CBX3 | chromobox homolog 3 | -0.0263549 |
| RPL38 | ribosomal protein L38 | -0.0263497 |
| NAALADL2 | N-acetylated alpha-linked acidic dipeptidase-like 2 | -0.0262114 |
| TUBB | tubulin, beta class I | -0.0258488 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0257714 |
| ABCC3 | ATP-binding cassette, sub-family C (CFTR/MRP), member 3 | -0.0256988 |
| RPS4X | ribosomal protein S4, X-linked | -0.0256213 |
| EIF5B | eukaryotic translation initiation factor 5B | -0.0255968 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0251443 |
| GPR39 | G protein-coupled receptor 39 | -0.0251379 |
| UQCRB | ubiquinol-cytochrome c reductase binding protein | -0.0251221 |
| BICC1 | BicC family RNA binding protein 1 | -0.0249251 |
| RPL28 | ribosomal protein L28 | -0.0248787 |
| RNF213 | ring finger protein 213 | -0.0245713 |
| MTAP | methylthioadenosine phosphorylase | -0.0242163 |
| SUMF1 | sulfatase modifying factor 1 | -0.0239059 |
| UBE2D2 | ubiquitin-conjugating enzyme E2D 2 | -0.0238627 |
| APOLD1 | apolipoprotein L domain containing 1 | -0.0235277 |
| ACTN4 | actinin, alpha 4 | -0.0234927 |
| POU5F1 | POU class 5 homeobox 1 | -0.0234105 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0233093 |
| S100A6 | S100 calcium binding protein A6 | -0.0230537 |
| SPATA13 | spermatogenesis associated 13 | -0.0230403 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0229716 |
| ENOSF1 | enolase superfamily member 1 | -0.0226262 |
| GSTP1 | glutathione S-transferase pi 1 | -0.0225604 |
| PAX8 | paired box 8 | -0.0225178 |
| VCL | vinculin | -0.0224851 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0218394 |
| HMGA1 | high mobility group AT-hook 1 | -0.0215938 |
| SH3TC2 | SH3 domain and tetratricopeptide repeats 2 | -0.021457 |
| RPS11 | ribosomal protein S11 | -0.0213469 |
| FTL | ferritin, light polypeptide | -0.0212754 |
| AIG1 | androgen-induced 1 | -0.0210596 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.021024 |
| ZBTB7A | zinc finger and BTB domain containing 7A | -0.0203481 |
| LMNA | lamin A/C | -0.0200606 |
| RPS14 | ribosomal protein S14 | -0.0199656 |
| RRM2 | ribonucleotide reductase M2 | -0.0199062 |
| CAPNS1 | calpain, small subunit 1 | -0.0198422 |
| EXOC4 | exocyst complex component 4 | -0.0197479 |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 | -0.0197062 |
| ERGIC1 | endoplasmic reticulum-golgi intermediate compartment (ERGIC) 1 | -0.0192427 |
| DOCK1 | dedicator of cytokinesis 1 | -0.0189759 |
