Cloxacillin (sodium)_HT-29 Gene Set

Dataset Tahoe Therapeutics Tahoe 100M Perturbation Atlas
Category transcriptomics
Type cell type
Description Cloxacillin (sodium) perturbation in HT-29 cell line (Tahoe Therapeutics)
Similar Terms
Downloads & Tools

Genes

200 genes differentially expressed following the Cloxacillin (sodium)_HT-29 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.

increased expression

Symbol Name Standardized Value
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) 0.174276
AHNAK AHNAK nucleoprotein 0.124398
SLC12A2 solute carrier family 12 (sodium/potassium/chloride transporter), member 2 0.110667
KRT20 keratin 20, type I 0.109478
EZR ezrin 0.107895
FTH1 ferritin, heavy polypeptide 1 0.1077
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group) 0.0933622
SNTB1 syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) 0.0796771
LMO7 LIM domain 7 0.0794604
PGK1 phosphoglycerate kinase 1 0.0784487
KRT8 keratin 8, type II 0.0691522
FAM13A family with sequence similarity 13, member A 0.0621848
ATXN1 ataxin 1 0.0534763
FRY furry homolog (Drosophila) 0.051535
PLOD2 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 0.0512822
MAML3 mastermind-like 3 (Drosophila) 0.0501462
SLC45A4 solute carrier family 45, member 4 0.0483352
ATF3 activating transcription factor 3 0.0472945
HDLBP high density lipoprotein binding protein 0.0468215
FNDC3B fibronectin type III domain containing 3B 0.0456996
ATP1B1 ATPase, Na+/K+ transporting, beta 1 polypeptide 0.0441757
H1-0 H1.0 linker histone 0.0435441
POF1B premature ovarian failure, 1B 0.0422743
PTPRK protein tyrosine phosphatase, receptor type, K 0.0421693
EMP1 epithelial membrane protein 1 0.0418012
BAIAP2L1 BAI1-associated protein 2-like 1 0.0416412
ERO1A endoplasmic reticulum oxidoreductase 1 alpha 0.0411353
FOSB FBJ murine osteosarcoma viral oncogene homolog B 0.0406471
JUN jun proto-oncogene 0.0402628
FBXO32 F-box protein 32 0.0399522
PDE4D phosphodiesterase 4D, cAMP-specific 0.0395193
PPP1R15A protein phosphatase 1, regulatory subunit 15A 0.0393089
PDIA4 protein disulfide isomerase family A, member 4 0.0388108
ENO1 enolase 1, (alpha) 0.0375488
FOS FBJ murine osteosarcoma viral oncogene homolog 0.0351896
CCSER1 coiled-coil serine-rich protein 1 0.034572
GAPDH glyceraldehyde-3-phosphate dehydrogenase 0.0341769
KDM3A lysine (K)-specific demethylase 3A 0.0341167
PITPNC1 phosphatidylinositol transfer protein, cytoplasmic 1 0.0334149
SCD stearoyl-CoA desaturase (delta-9-desaturase) 0.0329444
NT5DC3 5'-nucleotidase domain containing 3 0.0328847
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b 0.0313565
P4HA1 prolyl 4-hydroxylase, alpha polypeptide I 0.0305882
AGR2 anterior gradient 2 0.029837
MYH14 myosin, heavy chain 14, non-muscle 0.0295518
CANX calnexin 0.0284216
TNS1 tensin 1 0.0275793
RHPN2 rhophilin, Rho GTPase binding protein 2 0.0275415
KRT18 keratin 18, type I 0.0262354
PAPSS2 3'-phosphoadenosine 5'-phosphosulfate synthase 2 0.0259371
EPB41L5 erythrocyte membrane protein band 4.1 like 5 0.0257487
WDR45B WD repeat domain 45B 0.025478
NT5C2 5'-nucleotidase, cytosolic II 0.0249316
SORL1 sortilin-related receptor, L(DLR class) A repeats containing 0.024861
NAALADL2 N-acetylated alpha-linked acidic dipeptidase-like 2 0.0243284
PRKN parkin RBR E3 ubiquitin protein ligase 0.0242424
AFF1 AF4/FMR2 family, member 1 0.0239588
GMDS GDP-mannose 4,6-dehydratase 0.0239011
PRELID2 PRELI domain containing 2 0.0237969
GNGT1 guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1 0.0237532
LPIN2 lipin 2 0.0234426
CTBP2 C-terminal binding protein 2 0.0230919
VIM vimentin 0.0230319
BACE2 beta-site APP-cleaving enzyme 2 0.0228998
UGDH UDP-glucose 6-dehydrogenase 0.0226721
EXOC4 exocyst complex component 4 0.0225588
LPP LIM domain containing preferred translocation partner in lipoma 0.0224589
SPDYA speedy/RINGO cell cycle regulator family member A 0.0220609
ANXA1 annexin A1 0.0214725
HSD17B2 hydroxysteroid (17-beta) dehydrogenase 2 0.021294
TRIB1 tribbles pseudokinase 1 0.0210707
ACTN4 actinin, alpha 4 0.0204174
PMM2 phosphomannomutase 2 0.0202846
OXSR1 oxidative stress responsive 1 0.0201557
ANXA2 annexin A2 0.0200651
TLE4 transducin-like enhancer of split 4 0.0199639
CXCL8 chemokine (C-X-C motif) ligand 8 0.0198153
BTBD9 BTB (POZ) domain containing 9 0.0194599
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1 0.0192415
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3 0.0189421
LSR lipolysis stimulated lipoprotein receptor 0.0188747
FOXO3 forkhead box O3 0.0187387
B4GALNT3 beta-1,4-N-acetyl-galactosaminyl transferase 3 0.0185906
KLF6 Kruppel-like factor 6 0.0185805
ZMYND8 zinc finger, MYND-type containing 8 0.01852
ARHGAP32 Rho GTPase activating protein 32 0.0184116
PIP5K1B phosphatidylinositol-4-phosphate 5-kinase, type I, beta 0.0183893
ITGA1 integrin, alpha 1 0.0183062
MECOM MDS1 and EVI1 complex locus 0.018233
DUSP16 dual specificity phosphatase 16 0.018186
PDE10A phosphodiesterase 10A 0.0181747
TOX3 TOX high mobility group box family member 3 0.0179849
HKDC1 hexokinase domain containing 1 0.0179118
UTRN utrophin 0.0178677
CYSTM1 cysteine-rich transmembrane module containing 1 0.0178351
ABTB2 ankyrin repeat and BTB (POZ) domain containing 2 0.0177497
CCNYL1 cyclin Y-like 1 0.0175717
STXBP5 syntaxin binding protein 5 (tomosyn) 0.0174899
MGLL monoglyceride lipase 0.0174885
SLC38A1 solute carrier family 38, member 1 0.017411

decreased expression

Symbol Name Standardized Value
TXNRD1 thioredoxin reductase 1 -0.129545
RPS2 ribosomal protein S2 -0.113541
RPL21 ribosomal protein L21 -0.0881372
ADARB1 adenosine deaminase, RNA-specific, B1 -0.0793142
MBNL1 muscleblind-like splicing regulator 1 -0.0766071
RPS12 ribosomal protein S12 -0.0754432
ANKRD12 ankyrin repeat domain 12 -0.0709322
PABPC1 poly(A) binding protein, cytoplasmic 1 -0.0660014
PDZD8 PDZ domain containing 8 -0.065266
ARHGEF12 Rho guanine nucleotide exchange factor (GEF) 12 -0.0629203
TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa -0.0613789
RPL37A ribosomal protein L37a -0.0585606
ATAD2 ATPase family, AAA domain containing 2 -0.0574396
RPS6 ribosomal protein S6 -0.0568169
PLAUR plasminogen activator, urokinase receptor -0.0566275
DSCAM Down syndrome cell adhesion molecule -0.0564127
GOLGA4 golgin A4 -0.0558797
RPS3 ribosomal protein S3 -0.0540042
LIMA1 LIM domain and actin binding 1 -0.0538648
KMT2C lysine (K)-specific methyltransferase 2C -0.0538044
RBM39 RNA binding motif protein 39 -0.0517792
CTNND1 catenin (cadherin-associated protein), delta 1 -0.0514901
RPS19 ribosomal protein S19 -0.0507168
RPL7 ribosomal protein L7 -0.0503579
PHF20L1 PHD finger protein 20-like 1 -0.0498974
GSK3B glycogen synthase kinase 3 beta -0.0497799
LUC7L3 LUC7-like 3 (S. cerevisiae) -0.0497307
HNRNPA2B1 heterogeneous nuclear ribonucleoprotein A2/B1 -0.0496072
FAM135A family with sequence similarity 135, member A -0.0495918
KDM6A lysine (K)-specific demethylase 6A -0.049129
RPL9 ribosomal protein L9 -0.0484049
PRRC2C proline-rich coiled-coil 2C -0.0453771
SAMD12 sterile alpha motif domain containing 12 -0.044416
ERBIN erbb2 interacting protein -0.0442508
RPL11 ribosomal protein L11 -0.0436857
TAF1D TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa -0.0435013
MYO6 myosin VI -0.0434243
AKAP9 A kinase (PRKA) anchor protein 9 -0.0431719
UACA uveal autoantigen with coiled-coil domains and ankyrin repeats -0.04254
ANKRD17 ankyrin repeat domain 17 -0.0416469
PPP6R3 protein phosphatase 6, regulatory subunit 3 -0.0415421
RB1CC1 RB1-inducible coiled-coil 1 -0.0413816
NFKBIZ nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta -0.0410705
TOP2A topoisomerase (DNA) II alpha 170kDa -0.040497
ANKRD11 ankyrin repeat domain 11 -0.0401491
EIF4G2 eukaryotic translation initiation factor 4 gamma, 2 -0.0401297
SPAG9 sperm associated antigen 9 -0.0399701
TEAD1 TEA domain family member 1 (SV40 transcriptional enhancer factor) -0.0397819
RPL5 ribosomal protein L5 -0.0396991
B2M beta-2-microglobulin -0.0391937
CNBP CCHC-type zinc finger, nucleic acid binding protein -0.039142
SMG1 SMG1 phosphatidylinositol 3-kinase-related kinase -0.0385683
TAF2 TAF2 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 150kDa -0.0384154
NIPBL Nipped-B homolog (Drosophila) -0.0380143
WWC1 WW and C2 domain containing 1 -0.0378833
RPL23 ribosomal protein L23 -0.0378204
EIF3H eukaryotic translation initiation factor 3, subunit H -0.0377852
ZNF207 zinc finger protein 207 -0.0377292
RSF1 remodeling and spacing factor 1 -0.0377053
ASAP1 ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 -0.0374195
COG5 component of oligomeric golgi complex 5 -0.0372048
IPO7 importin 7 -0.0371855
PTEN phosphatase and tensin homolog -0.0368148
CSNK1A1 casein kinase 1, alpha 1 -0.0365109
RPS11 ribosomal protein S11 -0.0364242
CLTC clathrin, heavy chain (Hc) -0.0361049
NUFIP2 nuclear fragile X mental retardation protein interacting protein 2 -0.0359326
RPS17 ribosomal protein S17 -0.0358787
ACTR2 ARP2 actin-related protein 2 homolog (yeast) -0.0358334
UBR5 ubiquitin protein ligase E3 component n-recognin 5 -0.0356077
ARGLU1 arginine and glutamate rich 1 -0.0352399
ANKHD1 ankyrin repeat and KH domain containing 1 -0.0351794
CCNL1 cyclin L1 -0.0350815
PIK3C2A phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha -0.0350525
EFR3A EFR3 homolog A (S. cerevisiae) -0.0348373
NSMCE2 non-SMC element 2, MMS21 homolog (S. cerevisiae) -0.0348229
RPL37 ribosomal protein L37 -0.0347908
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin) -0.0347045
MACF1 microtubule-actin crosslinking factor 1 -0.0346325
POTEF POTE ankyrin domain family, member F -0.0345704
RPS16 ribosomal protein S16 -0.034546
MUC5AC mucin 5AC, oligomeric mucus/gel-forming -0.0344287
HERC1 HECT and RLD domain containing E3 ubiquitin protein ligase family member 1 -0.034422
RPLP2 ribosomal protein, large, P2 -0.0341522
DSTN destrin (actin depolymerizing factor) -0.034116
KDM2A lysine (K)-specific demethylase 2A -0.0340896
EIF3A eukaryotic translation initiation factor 3, subunit A -0.0339854
JMJD1C jumonji domain containing 1C -0.033953
ARID4B AT rich interactive domain 4B (RBP1-like) -0.0336046
KMT2E lysine (K)-specific methyltransferase 2E -0.0335414
PPP1R12A protein phosphatase 1, regulatory subunit 12A -0.0332151
CKAP5 cytoskeleton associated protein 5 -0.0330256
PCBP2 poly(rC) binding protein 2 -0.0329318
DIAPH3 diaphanous-related formin 3 -0.0328055
NCKAP1 NCK-associated protein 1 -0.0328051
ELF3 E74-like factor 3 (ets domain transcription factor, epithelial-specific ) -0.0327278
ZDHHC20 zinc finger, DHHC-type containing 20 -0.032369
PNISR PNN-interacting serine/arginine-rich protein -0.0322284
MSN moesin -0.0321974
CEP350 centrosomal protein 350kDa -0.0320689