| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Cloxacillin (sodium) perturbation in J82 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Cloxacillin (sodium)_J82 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.290154 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.213474 |
| AHNAK | AHNAK nucleoprotein | 0.115763 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.100836 |
| NAV2 | neuron navigator 2 | 0.0725005 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0689645 |
| RAI14 | retinoic acid induced 14 | 0.055913 |
| DTNA | dystrobrevin, alpha | 0.0552143 |
| PHACTR1 | phosphatase and actin regulator 1 | 0.0534587 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0528896 |
| ASPH | aspartate beta-hydroxylase | 0.0524634 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0515151 |
| MSN | moesin | 0.0514804 |
| DST | dystonin | 0.0499514 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0460529 |
| CANX | calnexin | 0.0454612 |
| ANXA2 | annexin A2 | 0.0440823 |
| ERBIN | erbb2 interacting protein | 0.0429949 |
| PTK2 | protein tyrosine kinase 2 | 0.0413483 |
| ZNF841 | zinc finger protein 841 | 0.0390827 |
| TPD52 | tumor protein D52 | 0.0388258 |
| ANXA1 | annexin A1 | 0.038272 |
| TPM3 | tropomyosin 3 | 0.0381608 |
| AFF1 | AF4/FMR2 family, member 1 | 0.0375624 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.0358557 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.0346917 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0345428 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0340456 |
| MKI67 | marker of proliferation Ki-67 | 0.0339173 |
| EPB41L2 | erythrocyte membrane protein band 4.1-like 2 | 0.0337164 |
| SET | SET nuclear proto-oncogene | 0.0336924 |
| PACS1 | phosphofurin acidic cluster sorting protein 1 | 0.032987 |
| YEATS2 | YEATS domain containing 2 | 0.0329206 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0324735 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0314611 |
| STK4 | serine/threonine kinase 4 | 0.0314207 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0313392 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0309081 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | 0.03039 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0301556 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0298156 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0293549 |
| EGFR | epidermal growth factor receptor | 0.0290984 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0286435 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0283057 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 | 0.0282776 |
| CORO1C | coronin, actin binding protein, 1C | 0.0278443 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.0276831 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0275039 |
| PDS5B | PDS5 cohesin associated factor B | 0.0272916 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0270046 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0269646 |
| SMYD3 | SET and MYND domain containing 3 | 0.0269558 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0268635 |
| PBX3 | pre-B-cell leukemia homeobox 3 | 0.026647 |
| NAV1 | neuron navigator 1 | 0.0265937 |
| FAM219A | family with sequence similarity 219, member A | 0.0263717 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0262906 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0261437 |
| ATAD2 | ATPase family, AAA domain containing 2 | 0.0260535 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0258707 |
| PODXL | podocalyxin-like | 0.0257398 |
| JUN | jun proto-oncogene | 0.025658 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0255685 |
| C1ORF21 | chromosome 1 open reading frame 21 | 0.0255626 |
| FMNL2 | formin-like 2 | 0.0253991 |
| CLIC4 | chloride intracellular channel 4 | 0.0253145 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0252536 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0252367 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0250824 |
| CEP250 | centrosomal protein 250kDa | 0.0247942 |
| ZNF292 | zinc finger protein 292 | 0.0246094 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0245955 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 | 0.0239859 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | 0.0238392 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0237504 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0237053 |
| ZNF638 | zinc finger protein 638 | 0.0235576 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0235416 |
| PTMA | prothymosin, alpha | 0.0231042 |
| RND3 | Rho family GTPase 3 | 0.0228252 |
| PDE10A | phosphodiesterase 10A | 0.0227522 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0227375 |
| FCHSD2 | FCH and double SH3 domains 2 | 0.0226819 |
| GMDS | GDP-mannose 4,6-dehydratase | 0.0226547 |
| RLF | rearranged L-myc fusion | 0.0226527 |
| ACTR3 | ARP3 actin-related protein 3 homolog (yeast) | 0.0226473 |
| ANO6 | anoctamin 6 | 0.0226398 |
| ADM | adrenomedullin | 0.0225617 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0224565 |
| MYCBP2 | MYC binding protein 2, E3 ubiquitin protein ligase | 0.0222449 |
| MYO10 | myosin X | 0.0222278 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0220584 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0218824 |
| FN1 | fibronectin 1 | 0.0218195 |
| KIF13A | kinesin family member 13A | 0.0217186 |
| MED13L | mediator complex subunit 13-like | 0.0215387 |
| MMP12 | matrix metallopeptidase 12 | 0.0214951 |
| FLNB | filamin B, beta | 0.0214638 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | 0.0214533 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HLA-B | major histocompatibility complex, class I, B | -0.25074 |
| MT2A | metallothionein 2A | -0.177244 |
| FTL | ferritin, light polypeptide | -0.120712 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0871737 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0846377 |
| TMSB10 | thymosin beta 10 | -0.0693332 |
| MT1X | metallothionein 1X | -0.0632107 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0581228 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.048989 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0482566 |
| B2M | beta-2-microglobulin | -0.0476394 |
| PFN1 | profilin 1 | -0.0467893 |
| SEC61A1 | Sec61 alpha 1 subunit (S. cerevisiae) | -0.045169 |
| CTSD | cathepsin D | -0.0450288 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0421009 |
| HLA-A | major histocompatibility complex, class I, A | -0.0419566 |
| HLA-C | major histocompatibility complex, class I, C | -0.0404066 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0398569 |
| ACTG1 | actin gamma 1 | -0.0398182 |
| RPLP2 | ribosomal protein, large, P2 | -0.0376671 |
| DEK | DEK proto-oncogene | -0.0330106 |
| OSMR | oncostatin M receptor | -0.0318918 |
| POSTN | periostin, osteoblast specific factor | -0.0318566 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0314798 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0311148 |
| RHOBTB3 | Rho-related BTB domain containing 3 | -0.0310532 |
| SULF1 | sulfatase 1 | -0.0293701 |
| RPL23 | ribosomal protein L23 | -0.028967 |
| RPL35A | ribosomal protein L35a | -0.0288154 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0287092 |
| GNAS | GNAS complex locus | -0.0281261 |
| TPI1 | triosephosphate isomerase 1 | -0.0280834 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0278515 |
| S100A6 | S100 calcium binding protein A6 | -0.0275636 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.0271532 |
| TUBB | tubulin, beta class I | -0.0259864 |
| TUBB4B | tubulin, beta 4B class IVb | -0.0258472 |
| SLC16A3 | solute carrier family 16 (monocarboxylate transporter), member 3 | -0.0256534 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0252207 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.025218 |
| VCL | vinculin | -0.024951 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0248609 |
| RPL37 | ribosomal protein L37 | -0.0247433 |
| HMGA1 | high mobility group AT-hook 1 | -0.0246256 |
| ZXDC | ZXD family zinc finger C | -0.0241142 |
| TGFB2 | transforming growth factor, beta 2 | -0.0231266 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0229489 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0225774 |
| RPS21 | ribosomal protein S21 | -0.0222445 |
| INTS6 | integrator complex subunit 6 | -0.022144 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | -0.0217973 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0210857 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0210612 |
| UQCRB | ubiquinol-cytochrome c reductase binding protein | -0.0206951 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0203254 |
| LMNA | lamin A/C | -0.0202737 |
| C6ORF62 | chromosome 6 open reading frame 62 | -0.0201889 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0200418 |
| CAP1 | CAP, adenylate cyclase-associated protein 1 (yeast) | -0.019983 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0198504 |
| TPM1 | tropomyosin 1 (alpha) | -0.0197661 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | -0.0195707 |
| ACTN4 | actinin, alpha 4 | -0.0195155 |
| TXNRD1 | thioredoxin reductase 1 | -0.0194857 |
| GANAB | glucosidase, alpha; neutral AB | -0.0194106 |
| SLC25A5 | solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5 | -0.0193303 |
| SEC22B | SEC22 vesicle trafficking protein homolog B (S. cerevisiae) (gene/pseudogene) | -0.0192539 |
| GNAI2 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2 | -0.0191564 |
| S100A10 | S100 calcium binding protein A10 | -0.0189696 |
| RPS13 | ribosomal protein S13 | -0.0187784 |
| HMGB1 | high mobility group box 1 | -0.0187192 |
| LAMP1 | lysosomal-associated membrane protein 1 | -0.0184333 |
| SQSTM1 | sequestosome 1 | -0.018374 |
| RPS19 | ribosomal protein S19 | -0.0182254 |
| CBX3 | chromobox homolog 3 | -0.0181271 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | -0.0177498 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0176425 |
| RPL11 | ribosomal protein L11 | -0.0175835 |
| UBE2V1 | ubiquitin-conjugating enzyme E2 variant 1 | -0.0174654 |
| SENP5 | SUMO1/sentrin specific peptidase 5 | -0.017414 |
| RPL30 | ribosomal protein L30 | -0.017253 |
| RAP1B | RAP1B, member of RAS oncogene family | -0.0171861 |
| RPL28 | ribosomal protein L28 | -0.0169223 |
| PSMA7 | proteasome (prosome, macropain) subunit, alpha type, 7 | -0.0167926 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0166783 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0166652 |
| B4GALT1 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1 | -0.0166249 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0165779 |
| SEC62 | SEC62 homolog (S. cerevisiae) | -0.0162619 |
| RBM25 | RNA binding motif protein 25 | -0.016213 |
| DIAPH3 | diaphanous-related formin 3 | -0.0161926 |
| RPL37A | ribosomal protein L37a | -0.0160578 |
| TBCA | tubulin folding cofactor A | -0.0160371 |
| NDRG1 | N-myc downstream regulated 1 | -0.0159769 |
| TUBA1C | tubulin, alpha 1c | -0.015872 |
| RPS24 | ribosomal protein S24 | -0.0158535 |
| EDF1 | endothelial differentiation-related factor 1 | -0.0158345 |
| SFPQ | splicing factor proline/glutamine-rich | -0.0157032 |
| SURF4 | surfeit 4 | -0.0155964 |
| ANKRD17 | ankyrin repeat domain 17 | -0.015586 |
