| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Cloxacillin (sodium) perturbation in KATO III cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Cloxacillin (sodium)_KATO III drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.10726 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0933085 |
| ANXA1 | annexin A1 | 0.0866732 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0860493 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0752942 |
| PGK1 | phosphoglycerate kinase 1 | 0.072404 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0659634 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0631781 |
| GOLGA4 | golgin A4 | 0.0630362 |
| EZR | ezrin | 0.0624311 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0621196 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0616834 |
| NEDD9 | neural precursor cell expressed, developmentally down-regulated 9 | 0.0607322 |
| ENO1 | enolase 1, (alpha) | 0.0527834 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0503239 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0488815 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0487402 |
| EEPD1 | endonuclease/exonuclease/phosphatase family domain containing 1 | 0.0486372 |
| NDRG1 | N-myc downstream regulated 1 | 0.0475983 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0470661 |
| ITGA6 | integrin, alpha 6 | 0.0465 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.04496 |
| FTL | ferritin, light polypeptide | 0.0436655 |
| CANX | calnexin | 0.0430649 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0426573 |
| RTN4 | reticulon 4 | 0.0421017 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.0410847 |
| B2M | beta-2-microglobulin | 0.0410487 |
| VEGFA | vascular endothelial growth factor A | 0.0394607 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0391438 |
| PKM | pyruvate kinase, muscle | 0.0388755 |
| TXNRD1 | thioredoxin reductase 1 | 0.0383799 |
| EMP1 | epithelial membrane protein 1 | 0.0383585 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0379098 |
| FAM13A | family with sequence similarity 13, member A | 0.0378486 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0377365 |
| ASPH | aspartate beta-hydroxylase | 0.0371474 |
| RPS6 | ribosomal protein S6 | 0.0361202 |
| TES | testin LIM domain protein | 0.0359262 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0359138 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0358659 |
| SFTPA2 | surfactant protein A2 | 0.035666 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0354889 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.035336 |
| TPM3 | tropomyosin 3 | 0.0351705 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0351316 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0349359 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.033937 |
| CDK6 | cyclin-dependent kinase 6 | 0.0327695 |
| TPD52 | tumor protein D52 | 0.0317959 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0313219 |
| AGR3 | anterior gradient 3 | 0.0312694 |
| LCN2 | lipocalin 2 | 0.0311924 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0310534 |
| YEATS2 | YEATS domain containing 2 | 0.0309585 |
| ZNF292 | zinc finger protein 292 | 0.0307656 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0307549 |
| WDR45B | WD repeat domain 45B | 0.030317 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0302775 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | 0.0298698 |
| CCNY | cyclin Y | 0.0295936 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | 0.0291542 |
| ANXA2 | annexin A2 | 0.0289195 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.028886 |
| ARF4 | ADP-ribosylation factor 4 | 0.0288349 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0286497 |
| HYOU1 | hypoxia up-regulated 1 | 0.027902 |
| PFKFB3 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 | 0.0278802 |
| PFKP | phosphofructokinase, platelet | 0.027378 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | 0.0273068 |
| TMF1 | TATA element modulatory factor 1 | 0.0268606 |
| JMJD1C | jumonji domain containing 1C | 0.0268434 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0265892 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0263623 |
| BRD4 | bromodomain containing 4 | 0.0262207 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0261091 |
| DSTN | destrin (actin depolymerizing factor) | 0.0260782 |
| DYNLT3 | dynein, light chain, Tctex-type 3 | 0.0259675 |
| ARHGAP12 | Rho GTPase activating protein 12 | 0.0259329 |
| FNDC3B | fibronectin type III domain containing 3B | 0.02565 |
| DSPP | dentin sialophosphoprotein | 0.025556 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0255321 |
| FAT1 | FAT atypical cadherin 1 | 0.0255173 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0252865 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0252005 |
| CALU | calumenin | 0.0251214 |
| RIN2 | Ras and Rab interactor 2 | 0.0250192 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 | 0.0247136 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0244928 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0243988 |
| TNIK | TRAF2 and NCK interacting kinase | 0.0241003 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0236841 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0236423 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0233721 |
| USP34 | ubiquitin specific peptidase 34 | 0.0229967 |
| H1-0 | H1.0 linker histone | 0.0227605 |
| PDS5A | PDS5 cohesin associated factor A | 0.0223096 |
| HM13 | histocompatibility (minor) 13 | 0.0221693 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0219836 |
| SMARCC1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 | 0.021699 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TMSB10 | thymosin beta 10 | -0.0851668 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0773102 |
| RRBP1 | ribosome binding protein 1 | -0.0610185 |
| S100A10 | S100 calcium binding protein A10 | -0.0472166 |
| RPL23 | ribosomal protein L23 | -0.0428285 |
| RPS24 | ribosomal protein S24 | -0.0422284 |
| RPLP1 | ribosomal protein, large, P1 | -0.0408361 |
| ACTG1 | actin gamma 1 | -0.0406754 |
| SH3RF1 | SH3 domain containing ring finger 1 | -0.0403936 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.040278 |
| ZC3H12B | zinc finger CCCH-type containing 12B | -0.0396931 |
| MUC17 | mucin 17, cell surface associated | -0.0393681 |
| S100A9 | S100 calcium binding protein A9 | -0.0389995 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.038907 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0383498 |
| KRT18 | keratin 18, type I | -0.0359662 |
| HLA-C | major histocompatibility complex, class I, C | -0.0354211 |
| S100A6 | S100 calcium binding protein A6 | -0.0353514 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | -0.0349815 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | -0.0349017 |
| ACTN4 | actinin, alpha 4 | -0.0348253 |
| EPB41L1 | erythrocyte membrane protein band 4.1-like 1 | -0.0347277 |
| JUP | junction plakoglobin | -0.0346371 |
| VCL | vinculin | -0.0320446 |
| C6ORF62 | chromosome 6 open reading frame 62 | -0.0316533 |
| PRSS3 | protease, serine, 3 | -0.0315737 |
| PTMA | prothymosin, alpha | -0.031333 |
| LMO7 | LIM domain 7 | -0.0311456 |
| RPS19 | ribosomal protein S19 | -0.0310626 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0298171 |
| KLF5 | Kruppel-like factor 5 (intestinal) | -0.0298019 |
| SLCO1B3-SLCO1B7 | SLCO1B3-SLCO1B7 readthrough | -0.0292594 |
| PLSCR1 | phospholipid scramblase 1 | -0.0291936 |
| PHF14 | PHD finger protein 14 | -0.0290239 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0279467 |
| HLA-E | major histocompatibility complex, class I, E | -0.0278651 |
| KLF6 | Kruppel-like factor 6 | -0.0277968 |
| H3-3B | H3.3 histone B | -0.0277391 |
| ATF7IP2 | activating transcription factor 7 interacting protein 2 | -0.0276181 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0275311 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0274935 |
| RPL35A | ribosomal protein L35a | -0.0273904 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.027238 |
| RPS21 | ribosomal protein S21 | -0.0272123 |
| INTS6 | integrator complex subunit 6 | -0.0269817 |
| CAPN8 | calpain 8 | -0.0266192 |
| RPLP2 | ribosomal protein, large, P2 | -0.0260522 |
| MYOF | myoferlin | -0.0257974 |
| RPL8 | ribosomal protein L8 | -0.0255062 |
| SLC20A2 | solute carrier family 20 (phosphate transporter), member 2 | -0.025496 |
| RPL28 | ribosomal protein L28 | -0.0252757 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0252727 |
| TMEM45B | transmembrane protein 45B | -0.0250396 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0249266 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0241071 |
| ARPC1B | actin related protein 2/3 complex, subunit 1B, 41kDa | -0.0236147 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.023388 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0233708 |
| BPTF | bromodomain PHD finger transcription factor | -0.0230845 |
| CDK12 | cyclin-dependent kinase 12 | -0.0230764 |
| HMGA1 | high mobility group AT-hook 1 | -0.0230139 |
| ATF5 | activating transcription factor 5 | -0.0226669 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.02257 |
| ZBTB7A | zinc finger and BTB domain containing 7A | -0.0224851 |
| CATSPERB | catsper channel auxiliary subunit beta | -0.0222413 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0221014 |
| GSTP1 | glutathione S-transferase pi 1 | -0.0220606 |
| TNRC18 | trinucleotide repeat containing 18 | -0.0219141 |
| OSBPL10 | oxysterol binding protein-like 10 | -0.0218898 |
| ZFP36L2 | ZFP36 ring finger protein-like 2 | -0.0218218 |
| KRT17 | keratin 17, type I | -0.0216197 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0215328 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0213988 |
| LURAP1L | leucine rich adaptor protein 1-like | -0.0211864 |
| RB1CC1 | RB1-inducible coiled-coil 1 | -0.0209579 |
| ITFG1 | integrin alpha FG-GAP repeat containing 1 | -0.0208222 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0203836 |
| NDUFA4 | NDUFA4, mitochondrial complex associated | -0.0203054 |
| POF1B | premature ovarian failure, 1B | -0.020186 |
| FDFT1 | farnesyl-diphosphate farnesyltransferase 1 | -0.0199681 |
| LHFPL2 | lipoma HMGIC fusion partner-like 2 | -0.0199677 |
| SH3D19 | SH3 domain containing 19 | -0.0198903 |
| CLTA | clathrin, light chain A | -0.0198575 |
| MED13L | mediator complex subunit 13-like | -0.0197622 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0195614 |
| ALDOC | aldolase C, fructose-bisphosphate | -0.0192289 |
| IER3 | immediate early response 3 | -0.0191479 |
| HMGB1 | high mobility group box 1 | -0.0190525 |
| RBBP6 | retinoblastoma binding protein 6 | -0.0189076 |
| FBXW7 | F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase | -0.0187058 |
| RPL32 | ribosomal protein L32 | -0.0186031 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0185652 |
| LAMB3 | laminin, beta 3 | -0.0185222 |
| ADAM32 | ADAM metallopeptidase domain 32 | -0.018447 |
| CTBP2 | C-terminal binding protein 2 | -0.0183994 |
| LASP1 | LIM and SH3 protein 1 | -0.0182267 |
| CFAP44 | cilia and flagella associated protein 44 | -0.0182008 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | -0.0181776 |
| TUBB4B | tubulin, beta 4B class IVb | -0.0181207 |
| RASAL2 | RAS protein activator like 2 | -0.0180762 |
