| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Cloxacillin (sodium) perturbation in MIA PaCa-2 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Cloxacillin (sodium)_MIA PaCa-2 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.149068 |
| DST | dystonin | 0.100257 |
| CAPRIN2 | caprin family member 2 | 0.0927506 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0708545 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0701039 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0655952 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0575836 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0566036 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0561286 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0523953 |
| INTS6 | integrator complex subunit 6 | 0.048084 |
| TSC22D1 | TSC22 domain family, member 1 | 0.0478137 |
| ZDHHC14 | zinc finger, DHHC-type containing 14 | 0.0474991 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0472162 |
| MYOF | myoferlin | 0.0468265 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0468 |
| CSMD3 | CUB and Sushi multiple domains 3 | 0.0460216 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0445512 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0444984 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0426891 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.0424986 |
| RPS6 | ribosomal protein S6 | 0.0413714 |
| LYST | lysosomal trafficking regulator | 0.0399529 |
| CADM2 | cell adhesion molecule 2 | 0.0399295 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0389023 |
| OSBPL8 | oxysterol binding protein-like 8 | 0.0388606 |
| TXNIP | thioredoxin interacting protein | 0.0383906 |
| EPHA4 | EPH receptor A4 | 0.0380118 |
| CD44 | CD44 molecule (Indian blood group) | 0.0380099 |
| HOMER1 | homer scaffolding protein 1 | 0.0377883 |
| AHNAK | AHNAK nucleoprotein | 0.0367794 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0356394 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0342391 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.0333773 |
| NAV2 | neuron navigator 2 | 0.0332094 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0331254 |
| HDAC9 | histone deacetylase 9 | 0.0327121 |
| SQSTM1 | sequestosome 1 | 0.0326247 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | 0.0310373 |
| HLA-B | major histocompatibility complex, class I, B | 0.0308881 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0299666 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | 0.02991 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | 0.0296184 |
| GOLGB1 | golgin B1 | 0.029518 |
| ALG13 | ALG13, UDP-N-acetylglucosaminyltransferase subunit | 0.0292 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0281673 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0280861 |
| GOLGA3 | golgin A3 | 0.0272247 |
| NR2F1 | nuclear receptor subfamily 2, group F, member 1 | 0.0268574 |
| AHI1 | Abelson helper integration site 1 | 0.0266403 |
| TRIM56 | tripartite motif containing 56 | 0.0263633 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | 0.0263264 |
| RPL37 | ribosomal protein L37 | 0.0261985 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.0255108 |
| KDM4C | lysine (K)-specific demethylase 4C | 0.0253548 |
| VEGFA | vascular endothelial growth factor A | 0.0249012 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0246009 |
| RPL19 | ribosomal protein L19 | 0.0245413 |
| GPATCH2 | G patch domain containing 2 | 0.0244982 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0241348 |
| ZKSCAN1 | zinc finger with KRAB and SCAN domains 1 | 0.0231581 |
| SEC24A | SEC24 family member A | 0.0231382 |
| ARHGAP12 | Rho GTPase activating protein 12 | 0.023045 |
| IARS1 | isoleucyl-tRNA synthetase 1 | 0.0230439 |
| TP63 | tumor protein p63 | 0.0228176 |
| EGFR | epidermal growth factor receptor | 0.0223328 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0222616 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) | 0.0222231 |
| HLA-A | major histocompatibility complex, class I, A | 0.0221639 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | 0.0220206 |
| CFLAR | CASP8 and FADD-like apoptosis regulator | 0.0220071 |
| ZBTB1 | zinc finger and BTB domain containing 1 | 0.0217056 |
| PHF10 | PHD finger protein 10 | 0.0216796 |
| SFTPA2 | surfactant protein A2 | 0.0213511 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | 0.0211624 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.021157 |
| PGM3 | phosphoglucomutase 3 | 0.0211163 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0210849 |
| RPL37A | ribosomal protein L37a | 0.0208712 |
| PDE10A | phosphodiesterase 10A | 0.0205123 |
| PDXK | pyridoxal (pyridoxine, vitamin B6) kinase | 0.0205097 |
| RAPH1 | Ras association (RalGDS/AF-6) and pleckstrin homology domains 1 | 0.0203856 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0201314 |
| RPL27 | ribosomal protein L27 | 0.0200352 |
| OAS3 | 2'-5'-oligoadenylate synthetase 3, 100kDa | 0.02003 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.019793 |
| EFNA5 | ephrin-A5 | 0.0197492 |
| ZBTB38 | zinc finger and BTB domain containing 38 | 0.0197121 |
| EPB41 | erythrocyte membrane protein band 4.1 | 0.0196762 |
| SLC38A1 | solute carrier family 38, member 1 | 0.0194716 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0193565 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0192505 |
| ADAM10 | ADAM metallopeptidase domain 10 | 0.019218 |
| ASNS | asparagine synthetase (glutamine-hydrolyzing) | 0.0192165 |
| KIAA1671 | KIAA1671 | 0.018932 |
| CCNL1 | cyclin L1 | 0.018618 |
| VMP1 | vacuole membrane protein 1 | 0.0185205 |
| PLIN2 | perilipin 2 | 0.0184189 |
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 | 0.0184112 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.0183922 |
| Symbol | Name | Standardized Value |
|---|---|---|
| MT2A | metallothionein 2A | -0.153304 |
| VIM | vimentin | -0.0830721 |
| RAD51B | RAD51 paralog B | -0.0830465 |
| TXNRD1 | thioredoxin reductase 1 | -0.0819473 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.071398 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0663599 |
| CENPF | centromere protein F, 350/400kDa | -0.0656931 |
| PTMA | prothymosin, alpha | -0.0563257 |
| SRPK2 | SRSF protein kinase 2 | -0.0557143 |
| TMSB4X | thymosin beta 4, X-linked | -0.053403 |
| EXOC4 | exocyst complex component 4 | -0.0515853 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0514899 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0513723 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0502504 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0498295 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | -0.0458521 |
| DIAPH3 | diaphanous-related formin 3 | -0.0455174 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0449597 |
| ACTG1 | actin gamma 1 | -0.0447464 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0432822 |
| RBM25 | RNA binding motif protein 25 | -0.0431265 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | -0.0397348 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0383726 |
| FLNB | filamin B, beta | -0.0381636 |
| SMAD3 | SMAD family member 3 | -0.0376767 |
| BRWD1 | bromodomain and WD repeat domain containing 1 | -0.0370961 |
| ETNK1 | ethanolamine kinase 1 | -0.0369167 |
| XPO1 | exportin 1 | -0.0369087 |
| RAI1 | retinoic acid induced 1 | -0.036167 |
| ZNF292 | zinc finger protein 292 | -0.0352109 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0338725 |
| USP9X | ubiquitin specific peptidase 9, X-linked | -0.033779 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0337326 |
| ANLN | anillin, actin binding protein | -0.0334666 |
| SBF2 | SET binding factor 2 | -0.0334198 |
| AFF4 | AF4/FMR2 family, member 4 | -0.0333269 |
| OLA1 | Obg-like ATPase 1 | -0.0333221 |
| LDHA | lactate dehydrogenase A | -0.0331291 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.0330827 |
| PRELID2 | PRELI domain containing 2 | -0.0328398 |
| ZNF217 | zinc finger protein 217 | -0.0327608 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0327547 |
| PGK1 | phosphoglycerate kinase 1 | -0.0320437 |
| SEPTIN7 | septin 7 | -0.0320112 |
| NSD2 | nuclear receptor binding SET domain protein 2 | -0.0317683 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0310635 |
| TMSB10 | thymosin beta 10 | -0.0308384 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0308014 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | -0.0307087 |
| SON | SON DNA binding protein | -0.0306068 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.030227 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0300897 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0300526 |
| MATR3 | matrin 3 | -0.0295504 |
| SYNCRIP | synaptotagmin binding, cytoplasmic RNA interacting protein | -0.0293361 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | -0.0292796 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | -0.029222 |
| GCLM | glutamate-cysteine ligase, modifier subunit | -0.0287555 |
| H1-0 | H1.0 linker histone | -0.0287502 |
| ACBD6 | acyl-CoA binding domain containing 6 | -0.0287327 |
| SINHCAF | SIN3-HDAC complex associated factor | -0.0286344 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | -0.0283124 |
| MKI67 | marker of proliferation Ki-67 | -0.0281228 |
| ACTN4 | actinin, alpha 4 | -0.028047 |
| PKM | pyruvate kinase, muscle | -0.0280307 |
| SPAG9 | sperm associated antigen 9 | -0.0277775 |
| RTTN | rotatin | -0.0277032 |
| PRRC2B | proline-rich coiled-coil 2B | -0.0276333 |
| PHIP | pleckstrin homology domain interacting protein | -0.0274755 |
| NUP153 | nucleoporin 153kDa | -0.0273067 |
| TNPO1 | transportin 1 | -0.0263587 |
| LUC7L2 | LUC7-like 2 (S. cerevisiae) | -0.0263547 |
| BMERB1 | bMERB domain containing 1 | -0.0262335 |
| RPL23 | ribosomal protein L23 | -0.0261893 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | -0.0261763 |
| KCMF1 | potassium channel modulatory factor 1 | -0.0261056 |
| POU2F1 | POU class 2 homeobox 1 | -0.0260033 |
| TCERG1 | transcription elongation regulator 1 | -0.0258385 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.025799 |
| CMSS1 | cms1 ribosomal small subunit homolog (yeast) | -0.0257899 |
| ACACA | acetyl-CoA carboxylase alpha | -0.0257234 |
| RBM26 | RNA binding motif protein 26 | -0.0256783 |
| WAC | WW domain containing adaptor with coiled-coil | -0.0255669 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | -0.0254175 |
| ATP9B | ATPase, class II, type 9B | -0.025389 |
| DPH6 | diphthamine biosynthesis 6 | -0.0251207 |
| NOP58 | NOP58 ribonucleoprotein | -0.0251048 |
| AHCTF1 | AT hook containing transcription factor 1 | -0.0250249 |
| XPO6 | exportin 6 | -0.0250078 |
| CHD1 | chromodomain helicase DNA binding protein 1 | -0.0247996 |
| SGO2 | shugoshin 2 | -0.0247617 |
| STRN3 | striatin, calmodulin binding protein 3 | -0.0245894 |
| QKI | QKI, KH domain containing, RNA binding | -0.0245782 |
| RRM2 | ribonucleotide reductase M2 | -0.0245688 |
| YBX1 | Y box binding protein 1 | -0.0245015 |
| SRGN | serglycin | -0.0244977 |
| RSRC1 | arginine/serine-rich coiled-coil 1 | -0.0244731 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | -0.0244586 |
| KMT2A | lysine (K)-specific methyltransferase 2A | -0.0243198 |
| KIAA1958 | KIAA1958 | -0.024279 |
