| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Cloxacillin (sodium) perturbation in NCI-H1792 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Cloxacillin (sodium)_NCI-H1792 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NAV2 | neuron navigator 2 | 0.0867427 |
| GRB10 | growth factor receptor-bound protein 10 | 0.083311 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | 0.0729854 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0711365 |
| FAM13A | family with sequence similarity 13, member A | 0.0702663 |
| SMAD3 | SMAD family member 3 | 0.0676547 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0652894 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0605251 |
| MEF2A | myocyte enhancer factor 2A | 0.0604151 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.0603701 |
| NGLY1 | N-glycanase 1 | 0.0530609 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0511739 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0498748 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | 0.0489112 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0478797 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0465458 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.045016 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0438906 |
| LOXL2 | lysyl oxidase-like 2 | 0.0434863 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.042128 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0419596 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0408956 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0408225 |
| RUNX1 | runt-related transcription factor 1 | 0.0381045 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0373935 |
| PIAS2 | protein inhibitor of activated STAT, 2 | 0.0364856 |
| ZNF638 | zinc finger protein 638 | 0.0359895 |
| EFNA5 | ephrin-A5 | 0.0351391 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0335507 |
| AMPD3 | adenosine monophosphate deaminase 3 | 0.0333312 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0321429 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.0319725 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0315822 |
| PARP8 | poly (ADP-ribose) polymerase family, member 8 | 0.0313633 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0312942 |
| RAI14 | retinoic acid induced 14 | 0.0308178 |
| PRELID2 | PRELI domain containing 2 | 0.0298472 |
| PDK3 | pyruvate dehydrogenase kinase, isozyme 3 | 0.0293082 |
| NFATC2 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 | 0.0292892 |
| DPYSL3 | dihydropyrimidinase-like 3 | 0.028186 |
| PYGL | phosphorylase, glycogen, liver | 0.0275535 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0275192 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.027054 |
| ZNRF1 | zinc and ring finger 1, E3 ubiquitin protein ligase | 0.0266639 |
| ANO6 | anoctamin 6 | 0.0265027 |
| VEGFA | vascular endothelial growth factor A | 0.0264812 |
| CA12 | carbonic anhydrase XII | 0.0263669 |
| LRRC8C | leucine rich repeat containing 8 family, member C | 0.0260411 |
| PFKP | phosphofructokinase, platelet | 0.0259819 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | 0.0256085 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.0251572 |
| DOCK5 | dedicator of cytokinesis 5 | 0.024903 |
| FAM107B | family with sequence similarity 107, member B | 0.0247249 |
| FAM219A | family with sequence similarity 219, member A | 0.0243741 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0242812 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | 0.0241154 |
| CDH13 | cadherin 13 | 0.0239707 |
| DTNA | dystrobrevin, alpha | 0.0238831 |
| ANKRD36 | ankyrin repeat domain 36 | 0.0238029 |
| GALNT18 | polypeptide N-acetylgalactosaminyltransferase 18 | 0.0234341 |
| DIP2C | DIP2 disco-interacting protein 2 homolog C (Drosophila) | 0.0234329 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0231652 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0226319 |
| GOLGA4 | golgin A4 | 0.0225821 |
| CEP250 | centrosomal protein 250kDa | 0.0225052 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0222619 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0222442 |
| ANKH | ANKH inorganic pyrophosphate transport regulator | 0.0221424 |
| SEPTIN9 | septin 9 | 0.0221003 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0218553 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0217656 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0216479 |
| KANSL1 | KAT8 regulatory NSL complex subunit 1 | 0.0214489 |
| MARCHF3 | membrane associated ring-CH-type finger 3 | 0.0213758 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0213664 |
| ADAMTS14 | ADAM metallopeptidase with thrombospondin type 1 motif, 14 | 0.0211839 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0209637 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0209287 |
| MTSS1 | metastasis suppressor 1 | 0.0209093 |
| TENT5A | terminal nucleotidyltransferase 5A | 0.020861 |
| GYS1 | glycogen synthase 1 (muscle) | 0.0208277 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | 0.020431 |
| FNIP1 | folliculin interacting protein 1 | 0.0204156 |
| TNS1 | tensin 1 | 0.0203536 |
| IGF1R | insulin-like growth factor 1 receptor | 0.0202081 |
| TPD52 | tumor protein D52 | 0.0201721 |
| ARFGEF3 | ARFGEF family member 3 | 0.0200115 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0199489 |
| ANKRD28 | ankyrin repeat domain 28 | 0.0199149 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | 0.019879 |
| MYO1E | myosin IE | 0.0198564 |
| PFKFB3 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 | 0.0198037 |
| EZR | ezrin | 0.0196564 |
| MAP2K1 | mitogen-activated protein kinase kinase 1 | 0.0195741 |
| TENT4A | terminal nucleotidyltransferase 4A | 0.0193871 |
| COL7A1 | collagen, type VII, alpha 1 | 0.0193666 |
| CRYBG3 | beta-gamma crystallin domain containing 3 | 0.0193449 |
| RARB | retinoic acid receptor, beta | 0.0192288 |
| SEC24A | SEC24 family member A | 0.0191221 |
| AHNAK | AHNAK nucleoprotein | 0.0190988 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TMSB10 | thymosin beta 10 | -0.235616 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.218675 |
| VIM | vimentin | -0.189125 |
| GLCCI1 | glucocorticoid induced 1 | -0.117847 |
| FTL | ferritin, light polypeptide | -0.104544 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0961227 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0800924 |
| CD44 | CD44 molecule (Indian blood group) | -0.0800343 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0732533 |
| PTMA | prothymosin, alpha | -0.0722731 |
| S100A6 | S100 calcium binding protein A6 | -0.0708896 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0670827 |
| MT2A | metallothionein 2A | -0.064031 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.062228 |
| OSMR | oncostatin M receptor | -0.056203 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0558848 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.0548371 |
| STC1 | stanniocalcin 1 | -0.0543047 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0526114 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0516936 |
| HMGA2 | high mobility group AT-hook 2 | -0.0508801 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0496873 |
| NRP1 | neuropilin 1 | -0.0475616 |
| NTN4 | netrin 4 | -0.04726 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0465776 |
| RPS21 | ribosomal protein S21 | -0.0463895 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0434613 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.043144 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0428823 |
| EGR1 | early growth response 1 | -0.041464 |
| RPL35A | ribosomal protein L35a | -0.0413685 |
| HMGA1 | high mobility group AT-hook 1 | -0.041016 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0407747 |
| VCL | vinculin | -0.0398993 |
| RPLP2 | ribosomal protein, large, P2 | -0.0397048 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | -0.0395135 |
| B2M | beta-2-microglobulin | -0.0393423 |
| RPS19 | ribosomal protein S19 | -0.0385994 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0384651 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0384517 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0383699 |
| HLA-B | major histocompatibility complex, class I, B | -0.038349 |
| TNNC1 | troponin C type 1 (slow) | -0.0379674 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0369003 |
| POTEF | POTE ankyrin domain family, member F | -0.036376 |
| S100A10 | S100 calcium binding protein A10 | -0.0357164 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0344796 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | -0.0341013 |
| RBMS1 | RNA binding motif, single stranded interacting protein 1 | -0.0336952 |
| RPL34 | ribosomal protein L34 | -0.0335141 |
| VRK2 | vaccinia related kinase 2 | -0.0330674 |
| RPS24 | ribosomal protein S24 | -0.0329681 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0325094 |
| RAP1B | RAP1B, member of RAS oncogene family | -0.0324544 |
| NCOA7 | nuclear receptor coactivator 7 | -0.03236 |
| LOX | lysyl oxidase | -0.0322905 |
| RPLP1 | ribosomal protein, large, P1 | -0.0318693 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0314377 |
| NUMB | numb homolog (Drosophila) | -0.0312339 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0312333 |
| RAB27B | RAB27B, member RAS oncogene family | -0.0311695 |
| SAMD9 | sterile alpha motif domain containing 9 | -0.0309994 |
| PRSS23 | protease, serine, 23 | -0.0309956 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0308963 |
| C15ORF48 | chromosome 15 open reading frame 48 | -0.0300052 |
| NF1 | neurofibromin 1 | -0.0291349 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0290431 |
| ACTG1 | actin gamma 1 | -0.0284047 |
| RPL37A | ribosomal protein L37a | -0.0282092 |
| TMEM131 | transmembrane protein 131 | -0.0278746 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | -0.0276205 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0273571 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | -0.0271415 |
| SP100 | SP100 nuclear antigen | -0.0268956 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0264647 |
| RPL36 | ribosomal protein L36 | -0.0262093 |
| ZBTB7A | zinc finger and BTB domain containing 7A | -0.0261854 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0260228 |
| ZNF804A | zinc finger protein 804A | -0.0259817 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0259397 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0256913 |
| CCNI | cyclin I | -0.0256542 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0254451 |
| MAP1B | microtubule-associated protein 1B | -0.0253519 |
| GLIS3 | GLIS family zinc finger 3 | -0.0253469 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0252444 |
| KYNU | kynureninase | -0.0251613 |
| PID1 | phosphotyrosine interaction domain containing 1 | -0.0251307 |
| RPS8 | ribosomal protein S8 | -0.0249123 |
| COL12A1 | collagen, type XII, alpha 1 | -0.0248548 |
| IER3 | immediate early response 3 | -0.0248141 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0246797 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0246405 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0245373 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0244768 |
| RPL32 | ribosomal protein L32 | -0.0243807 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0242594 |
| THBD | thrombomodulin | -0.0242144 |
| TMSB4X | thymosin beta 4, X-linked | -0.0241186 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0237526 |