| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Cloxacillin (sodium) perturbation in NCI-H2030 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Cloxacillin (sodium)_NCI-H2030 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| KTN1 | kinectin 1 (kinesin receptor) | 0.0681064 |
| RBM25 | RNA binding motif protein 25 | 0.0635319 |
| COPA | coatomer protein complex, subunit alpha | 0.0619703 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0612664 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0602171 |
| FMNL2 | formin-like 2 | 0.059721 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0585423 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0574909 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0559459 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0533788 |
| SMOC1 | SPARC related modular calcium binding 1 | 0.0526515 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0509511 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0507141 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0476098 |
| BRD2 | bromodomain containing 2 | 0.0472705 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0467818 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | 0.0458239 |
| TPM3 | tropomyosin 3 | 0.0455502 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.044825 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0448053 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0446873 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0442799 |
| CCNL1 | cyclin L1 | 0.0441959 |
| GOLGA4 | golgin A4 | 0.0440425 |
| FAM107B | family with sequence similarity 107, member B | 0.0425448 |
| CUL3 | cullin 3 | 0.0422958 |
| MCL1 | myeloid cell leukemia 1 | 0.0421471 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0392786 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0390711 |
| USP36 | ubiquitin specific peptidase 36 | 0.0378556 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0372724 |
| PCBP2 | poly(rC) binding protein 2 | 0.0369534 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0368597 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0358153 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0357989 |
| TOP1 | topoisomerase (DNA) I | 0.0357538 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0356029 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0353852 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0353356 |
| WDR43 | WD repeat domain 43 | 0.0353176 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0343254 |
| NOP58 | NOP58 ribonucleoprotein | 0.0338862 |
| FLNB | filamin B, beta | 0.0335241 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0335227 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0335193 |
| RNF145 | ring finger protein 145 | 0.0334295 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | 0.0331094 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0328918 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.0318815 |
| HELZ | helicase with zinc finger | 0.0317862 |
| RBM39 | RNA binding motif protein 39 | 0.0314628 |
| DOCK4 | dedicator of cytokinesis 4 | 0.0312162 |
| ZNF207 | zinc finger protein 207 | 0.0311229 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0308247 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.030548 |
| MSN | moesin | 0.0302365 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0301186 |
| SLMAP | sarcolemma associated protein | 0.0300739 |
| EIF5 | eukaryotic translation initiation factor 5 | 0.0300088 |
| ACTN1 | actinin, alpha 1 | 0.0298627 |
| KIF5B | kinesin family member 5B | 0.0297303 |
| SPAG9 | sperm associated antigen 9 | 0.0294644 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.0294397 |
| PARD3 | par-3 family cell polarity regulator | 0.0291105 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | 0.0290288 |
| CTBP2 | C-terminal binding protein 2 | 0.0290062 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.028842 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 | 0.0288276 |
| NDRG1 | N-myc downstream regulated 1 | 0.0283186 |
| TFG | TRK-fused gene | 0.02819 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0281715 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0279726 |
| MED13 | mediator complex subunit 13 | 0.027655 |
| EPG5 | ectopic P-granules autophagy protein 5 homolog (C. elegans) | 0.0274452 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0271267 |
| PSMD14 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 | 0.0269259 |
| SRP54 | signal recognition particle 54kDa | 0.0267409 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0266792 |
| KDM5B | lysine (K)-specific demethylase 5B | 0.0266684 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.026125 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0258179 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 0.0257879 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0256692 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0255999 |
| TLK1 | tousled-like kinase 1 | 0.0252335 |
| ARHGAP26 | Rho GTPase activating protein 26 | 0.0252272 |
| HNRNPM | heterogeneous nuclear ribonucleoprotein M | 0.0249732 |
| PUM1 | pumilio RNA-binding family member 1 | 0.0247951 |
| FBXO11 | F-box protein 11 | 0.0245758 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0243531 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.024311 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0238955 |
| UBAP2L | ubiquitin associated protein 2-like | 0.0238393 |
| GLG1 | golgi glycoprotein 1 | 0.023739 |
| POTEF | POTE ankyrin domain family, member F | 0.0237337 |
| SUCO | SUN domain containing ossification factor | 0.0234992 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0234629 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0233478 |
| BRD4 | bromodomain containing 4 | 0.0233392 |
| PRPF40A | PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae) | 0.0232826 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.266324 |
| TMSB10 | thymosin beta 10 | -0.159525 |
| FTL | ferritin, light polypeptide | -0.152447 |
| GRAMD1B | GRAM domain containing 1B | -0.142882 |
| TXNRD1 | thioredoxin reductase 1 | -0.133662 |
| MT2A | metallothionein 2A | -0.121702 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.104145 |
| PM20D1 | peptidase M20 domain containing 1 | -0.0982161 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0968186 |
| VIM | vimentin | -0.0963201 |
| RPL19 | ribosomal protein L19 | -0.0745483 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0658907 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0633117 |
| RPL23 | ribosomal protein L23 | -0.0584469 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.053368 |
| S100A6 | S100 calcium binding protein A6 | -0.0508082 |
| RPS21 | ribosomal protein S21 | -0.0501384 |
| S100A10 | S100 calcium binding protein A10 | -0.0471645 |
| PTMA | prothymosin, alpha | -0.0470201 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0469865 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0468064 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0467031 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.0461438 |
| RPS25 | ribosomal protein S25 | -0.0449314 |
| RPLP0 | ribosomal protein, large, P0 | -0.0427605 |
| RPLP1 | ribosomal protein, large, P1 | -0.0426991 |
| OSMR | oncostatin M receptor | -0.0414672 |
| C15ORF48 | chromosome 15 open reading frame 48 | -0.0407052 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0389989 |
| BICC1 | BicC family RNA binding protein 1 | -0.0367941 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0367322 |
| CFLAR | CASP8 and FADD-like apoptosis regulator | -0.0367091 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0365837 |
| IER3 | immediate early response 3 | -0.0361354 |
| RPS5 | ribosomal protein S5 | -0.0358905 |
| EFNA5 | ephrin-A5 | -0.0356943 |
| NQO1 | NAD(P)H dehydrogenase, quinone 1 | -0.0356546 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0352342 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0351051 |
| LANCL1 | LanC lantibiotic synthetase component C-like 1 (bacterial) | -0.0341233 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0339188 |
| RPL35A | ribosomal protein L35a | -0.0330904 |
| RPS16 | ribosomal protein S16 | -0.032289 |
| RPS23 | ribosomal protein S23 | -0.0316979 |
| RPL8 | ribosomal protein L8 | -0.0307878 |
| RPS24 | ribosomal protein S24 | -0.0307043 |
| KLF6 | Kruppel-like factor 6 | -0.0305622 |
| HDAC9 | histone deacetylase 9 | -0.0304809 |
| AHNAK | AHNAK nucleoprotein | -0.0298083 |
| RPS15 | ribosomal protein S15 | -0.029556 |
| RPS19 | ribosomal protein S19 | -0.0291092 |
| S100A9 | S100 calcium binding protein A9 | -0.0290043 |
| RPL36 | ribosomal protein L36 | -0.0289361 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0288583 |
| RPS20 | ribosomal protein S20 | -0.0285518 |
| SERF2 | small EDRK-rich factor 2 | -0.0281245 |
| RPS27A | ribosomal protein S27a | -0.0278591 |
| RPL34 | ribosomal protein L34 | -0.027382 |
| RPS29 | ribosomal protein S29 | -0.0273012 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0271437 |
| NNMT | nicotinamide N-methyltransferase | -0.026645 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0264701 |
| ANXA2 | annexin A2 | -0.0264072 |
| RPL37 | ribosomal protein L37 | -0.0263782 |
| RPL7 | ribosomal protein L7 | -0.0255155 |
| FGB | fibrinogen beta chain | -0.0254808 |
| PTP4A1 | protein tyrosine phosphatase type IVA, member 1 | -0.025181 |
| RPL31 | ribosomal protein L31 | -0.0248943 |
| RHOA | ras homolog family member A | -0.0245343 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0244457 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0244317 |
| RPL4 | ribosomal protein L4 | -0.0242384 |
| RPS8 | ribosomal protein S8 | -0.0239619 |
| TMEM123 | transmembrane protein 123 | -0.0238305 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.0236185 |
| RPL30 | ribosomal protein L30 | -0.023615 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | -0.0233623 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0233456 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0232351 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | -0.0224562 |
| CAVIN1 | caveolae associated protein 1 | -0.0223296 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0222936 |
| IGF1R | insulin-like growth factor 1 receptor | -0.0219721 |
| PFDN2 | prefoldin subunit 2 | -0.021787 |
| SVIL | supervillin | -0.0216826 |
| ITFG1 | integrin alpha FG-GAP repeat containing 1 | -0.0215695 |
| RPS14 | ribosomal protein S14 | -0.0210056 |
| AHR | aryl hydrocarbon receptor | -0.0209027 |
| NPC1 | Niemann-Pick disease, type C1 | -0.0207261 |
| SRP14 | signal recognition particle 14kDa (homologous Alu RNA binding protein) | -0.0206639 |
| RPL26 | ribosomal protein L26 | -0.0203856 |
| RPL11 | ribosomal protein L11 | -0.0201293 |
| RPL38 | ribosomal protein L38 | -0.0200353 |
| MAP3K20 | mitogen-activated protein kinase kinase kinase 20 | -0.0200261 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0196539 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.0192793 |
| FDPS | farnesyl diphosphate synthase | -0.0192103 |
| BHLHE40 | basic helix-loop-helix family, member e40 | -0.0191887 |
| RPS27 | ribosomal protein S27 | -0.0190216 |
| PYGL | phosphorylase, glycogen, liver | -0.0188289 |
