| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Cloxacillin (sodium) perturbation in NCI-H23 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Cloxacillin (sodium)_NCI-H23 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.175037 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | 0.106166 |
| MCL1 | myeloid cell leukemia 1 | 0.105141 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0798579 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0789291 |
| MDGA2 | MAM domain containing glycosylphosphatidylinositol anchor 2 | 0.0705307 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0653963 |
| COPA | coatomer protein complex, subunit alpha | 0.0650751 |
| AFF3 | AF4/FMR2 family, member 3 | 0.0639058 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0578666 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.054741 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0533079 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0529717 |
| INTS6 | integrator complex subunit 6 | 0.0517286 |
| AEBP2 | AE binding protein 2 | 0.0480251 |
| GOLGB1 | golgin B1 | 0.0478928 |
| PRELID2 | PRELI domain containing 2 | 0.0473402 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0468583 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0465181 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | 0.0431774 |
| YBX3 | Y box binding protein 3 | 0.0427856 |
| BRD2 | bromodomain containing 2 | 0.0411261 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0401228 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0395748 |
| PDE10A | phosphodiesterase 10A | 0.0393594 |
| PRKCE | protein kinase C, epsilon | 0.0390875 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0376599 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | 0.0371263 |
| FMNL2 | formin-like 2 | 0.0371083 |
| TPM3 | tropomyosin 3 | 0.0360959 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0359991 |
| SND1 | staphylococcal nuclease and tudor domain containing 1 | 0.0356197 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0355651 |
| VMP1 | vacuole membrane protein 1 | 0.0353083 |
| CCNL1 | cyclin L1 | 0.0352086 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0338558 |
| MCTP1 | multiple C2 domains, transmembrane 1 | 0.0337052 |
| MBD5 | methyl-CpG binding domain protein 5 | 0.0333006 |
| WNT2B | wingless-type MMTV integration site family, member 2B | 0.0317465 |
| TLN1 | talin 1 | 0.0316137 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0314858 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0312918 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0305958 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0303602 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0302028 |
| EGR1 | early growth response 1 | 0.0299377 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | 0.029594 |
| PRH1 | proline-rich protein HaeIII subfamily 1 | 0.029577 |
| HOMER1 | homer scaffolding protein 1 | 0.0293498 |
| ATXN1 | ataxin 1 | 0.0293292 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0290805 |
| OSMR | oncostatin M receptor | 0.0279912 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0273231 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.027222 |
| ATP2A2 | ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 | 0.0272212 |
| EIF2AK3 | eukaryotic translation initiation factor 2-alpha kinase 3 | 0.0264601 |
| CNOT4 | CCR4-NOT transcription complex, subunit 4 | 0.0262347 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0256611 |
| OGA | O-GlcNAcase | 0.0254005 |
| NEK10 | NIMA-related kinase 10 | 0.0253733 |
| ZBTB1 | zinc finger and BTB domain containing 1 | 0.0250757 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0249381 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0248842 |
| WNK1 | WNK lysine deficient protein kinase 1 | 0.0244575 |
| RBM39 | RNA binding motif protein 39 | 0.0244418 |
| DCAF8 | DDB1 and CUL4 associated factor 8 | 0.0244193 |
| GPATCH2L | G patch domain containing 2-like | 0.0244094 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0242031 |
| ANO6 | anoctamin 6 | 0.0241309 |
| NABP1 | nucleic acid binding protein 1 | 0.0241121 |
| JMJD1C | jumonji domain containing 1C | 0.0240608 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0240561 |
| WWOX | WW domain containing oxidoreductase | 0.0239962 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0236253 |
| YAP1 | Yes-associated protein 1 | 0.0228783 |
| USP34 | ubiquitin specific peptidase 34 | 0.0227366 |
| UMAD1 | UBAP1-MVB12-associated (UMA) domain containing 1 | 0.0225575 |
| PYGL | phosphorylase, glycogen, liver | 0.0225226 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0224568 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0224259 |
| SETX | senataxin | 0.0224259 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0223705 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0218462 |
| HDAC4 | histone deacetylase 4 | 0.0218129 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.021779 |
| SVIL | supervillin | 0.0215243 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0214294 |
| SLC9A1 | solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1 | 0.0213056 |
| TRIP12 | thyroid hormone receptor interactor 12 | 0.0213048 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | 0.0212947 |
| NDEL1 | nudE neurodevelopment protein 1-like 1 | 0.0212147 |
| VCL | vinculin | 0.0210728 |
| AGO3 | argonaute RISC catalytic component 3 | 0.0210013 |
| EPC2 | enhancer of polycomb homolog 2 (Drosophila) | 0.0208155 |
| ATP11A | ATPase, class VI, type 11A | 0.0207548 |
| ATF6 | activating transcription factor 6 | 0.0202548 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0200011 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.0199652 |
| FNIP1 | folliculin interacting protein 1 | 0.0199531 |
| ZNF638 | zinc finger protein 638 | 0.0198858 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.195245 |
| TXNRD1 | thioredoxin reductase 1 | -0.10634 |
| VIM | vimentin | -0.104068 |
| PTMA | prothymosin, alpha | -0.102941 |
| TMSB10 | thymosin beta 10 | -0.101889 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.101119 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0718687 |
| TPI1 | triosephosphate isomerase 1 | -0.0622852 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0583454 |
| RPS21 | ribosomal protein S21 | -0.0561275 |
| GRAMD1B | GRAM domain containing 1B | -0.055415 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0480457 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0472872 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0420977 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0413779 |
| CENPF | centromere protein F, 350/400kDa | -0.0411073 |
| RPL35A | ribosomal protein L35a | -0.0405487 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0401945 |
| RPL23 | ribosomal protein L23 | -0.0400189 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.0397016 |
| RPL12 | ribosomal protein L12 | -0.0389084 |
| PHF20 | PHD finger protein 20 | -0.0375913 |
| MT2A | metallothionein 2A | -0.0375285 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | -0.0365732 |
| RPLP0 | ribosomal protein, large, P0 | -0.0364522 |
| RPS8 | ribosomal protein S8 | -0.0361793 |
| MKI67 | marker of proliferation Ki-67 | -0.0360043 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0357888 |
| RPL26 | ribosomal protein L26 | -0.035508 |
| RPL32 | ribosomal protein L32 | -0.0352063 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0331334 |
| CBX3 | chromobox homolog 3 | -0.0331103 |
| RPL19 | ribosomal protein L19 | -0.0328129 |
| RPLP1 | ribosomal protein, large, P1 | -0.0327423 |
| DEK | DEK proto-oncogene | -0.0327139 |
| RPLP2 | ribosomal protein, large, P2 | -0.0326007 |
| CSDE1 | cold shock domain containing E1, RNA-binding | -0.0323958 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0321303 |
| HMGA1 | high mobility group AT-hook 1 | -0.0315103 |
| ZFR | zinc finger RNA binding protein | -0.0312658 |
| RPS27A | ribosomal protein S27a | -0.030955 |
| XPO1 | exportin 1 | -0.0307995 |
| RPS3 | ribosomal protein S3 | -0.0307432 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0304467 |
| RPS24 | ribosomal protein S24 | -0.0303746 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.030333 |
| LDHB | lactate dehydrogenase B | -0.0298195 |
| FTL | ferritin, light polypeptide | -0.0293877 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0291128 |
| RPS27 | ribosomal protein S27 | -0.0291116 |
| PPP2R5E | protein phosphatase 2, regulatory subunit B', epsilon isoform | -0.0290382 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0289496 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0288638 |
| RPL8 | ribosomal protein L8 | -0.0288462 |
| CAVIN1 | caveolae associated protein 1 | -0.0284476 |
| SINHCAF | SIN3-HDAC complex associated factor | -0.0273895 |
| RPL38 | ribosomal protein L38 | -0.0273699 |
| RPL36A | ribosomal protein L36a | -0.0273108 |
| RPL34 | ribosomal protein L34 | -0.0272129 |
| RPS29 | ribosomal protein S29 | -0.0267493 |
| GATAD2B | GATA zinc finger domain containing 2B | -0.026644 |
| TPX2 | TPX2, microtubule-associated | -0.0265202 |
| S100A6 | S100 calcium binding protein A6 | -0.0264829 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | -0.0264334 |
| PFN1 | profilin 1 | -0.0263767 |
| RPS4X | ribosomal protein S4, X-linked | -0.0260494 |
| KLF6 | Kruppel-like factor 6 | -0.0260078 |
| PHIP | pleckstrin homology domain interacting protein | -0.025812 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0254479 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.025284 |
| CAP1 | CAP, adenylate cyclase-associated protein 1 (yeast) | -0.0248382 |
| THOC2 | THO complex 2 | -0.0246746 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0243966 |
| RPL37 | ribosomal protein L37 | -0.0241532 |
| NCAPD2 | non-SMC condensin I complex, subunit D2 | -0.0241067 |
| RPL11 | ribosomal protein L11 | -0.0239084 |
| KIF18B | kinesin family member 18B | -0.023648 |
| IGF2BP1 | insulin-like growth factor 2 mRNA binding protein 1 | -0.0235443 |
| EML4 | echinoderm microtubule associated protein like 4 | -0.02353 |
| RPS15 | ribosomal protein S15 | -0.0234885 |
| RPL31 | ribosomal protein L31 | -0.0234849 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0233368 |
| SSB | Sjogren syndrome antigen B (autoantigen La) | -0.0230849 |
| GNAS | GNAS complex locus | -0.0230112 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0229635 |
| NR6A1 | nuclear receptor subfamily 6, group A, member 1 | -0.0228929 |
| RPL5 | ribosomal protein L5 | -0.0228831 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0227999 |
| KRT18 | keratin 18, type I | -0.0227602 |
| CCND1 | cyclin D1 | -0.0227464 |
| SGO2 | shugoshin 2 | -0.0227307 |
| DENND5B | DENN/MADD domain containing 5B | -0.0226189 |
| WASF2 | WAS protein family, member 2 | -0.022555 |
| SRPK2 | SRSF protein kinase 2 | -0.0224439 |
| SBNO1 | strawberry notch homolog 1 (Drosophila) | -0.0223714 |
| CDC27 | cell division cycle 27 | -0.0223564 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.022312 |
| RPS19 | ribosomal protein S19 | -0.0223105 |
| ACTG1 | actin gamma 1 | -0.022246 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0222142 |
