| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Cloxacillin (sodium) perturbation in NCI-H2347 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Cloxacillin (sodium)_NCI-H2347 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.227242 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.153046 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.148123 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.103844 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.102579 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0857165 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0796189 |
| POTEF | POTE ankyrin domain family, member F | 0.0674545 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0653607 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0645549 |
| MSN | moesin | 0.0639555 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0609505 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.059611 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0587465 |
| VEGFA | vascular endothelial growth factor A | 0.057782 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0567851 |
| CCNL1 | cyclin L1 | 0.0567225 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0565566 |
| BRD2 | bromodomain containing 2 | 0.055077 |
| PCBP2 | poly(rC) binding protein 2 | 0.0549821 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0533871 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0532937 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0521654 |
| FAM13A | family with sequence similarity 13, member A | 0.0518372 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0516061 |
| TPM3 | tropomyosin 3 | 0.050779 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0499487 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0479125 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0470414 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0465319 |
| PPARD | peroxisome proliferator-activated receptor delta | 0.0462612 |
| CANX | calnexin | 0.045793 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0452314 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0451513 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0442691 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0420695 |
| DUSP10 | dual specificity phosphatase 10 | 0.041465 |
| PAPOLA | poly(A) polymerase alpha | 0.0408447 |
| EZR | ezrin | 0.0394662 |
| PTK2 | protein tyrosine kinase 2 | 0.0386718 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.037513 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0371479 |
| TUFT1 | tuftelin 1 | 0.0363673 |
| NDRG1 | N-myc downstream regulated 1 | 0.036307 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0362438 |
| TMF1 | TATA element modulatory factor 1 | 0.0358571 |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like | 0.0358308 |
| RNF145 | ring finger protein 145 | 0.0355535 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.034635 |
| MCL1 | myeloid cell leukemia 1 | 0.034442 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0339565 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | 0.0338037 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0337959 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0337333 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0335236 |
| EGR1 | early growth response 1 | 0.0334727 |
| PPP1R13B | protein phosphatase 1, regulatory subunit 13B | 0.0329725 |
| KHDRBS3 | KH domain containing, RNA binding, signal transduction associated 3 | 0.0325292 |
| RPL3 | ribosomal protein L3 | 0.0324826 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0323395 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0322988 |
| DSPP | dentin sialophosphoprotein | 0.0320532 |
| YBX1 | Y box binding protein 1 | 0.0319784 |
| EIF5 | eukaryotic translation initiation factor 5 | 0.0317608 |
| RYBP | RING1 and YY1 binding protein | 0.0313125 |
| SET | SET nuclear proto-oncogene | 0.0310067 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0309305 |
| COPA | coatomer protein complex, subunit alpha | 0.0303503 |
| RCOR1 | REST corepressor 1 | 0.0298299 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0296854 |
| USP53 | ubiquitin specific peptidase 53 | 0.0295256 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.029099 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0290811 |
| DIAPH1 | diaphanous-related formin 1 | 0.0288633 |
| PLEC | plectin | 0.0286786 |
| GOLGB1 | golgin B1 | 0.0286541 |
| PCM1 | pericentriolar material 1 | 0.0282242 |
| MED13 | mediator complex subunit 13 | 0.0281162 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0280323 |
| YAP1 | Yes-associated protein 1 | 0.0277342 |
| SDC4 | syndecan 4 | 0.0273833 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0272469 |
| NPTN | neuroplastin | 0.0272419 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0265213 |
| MYO5B | myosin VB | 0.0265211 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.026088 |
| HNRNPM | heterogeneous nuclear ribonucleoprotein M | 0.0259832 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0258939 |
| SGMS2 | sphingomyelin synthase 2 | 0.0255693 |
| RPS2 | ribosomal protein S2 | 0.0253169 |
| ANXA5 | annexin A5 | 0.0248948 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0247538 |
| IFRD1 | interferon-related developmental regulator 1 | 0.0247362 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.0245317 |
| ZNF654 | zinc finger protein 654 | 0.0245015 |
| TRA2B | transformer 2 beta homolog (Drosophila) | 0.0244858 |
| SPSB1 | splA/ryanodine receptor domain and SOCS box containing 1 | 0.0243756 |
| RBM25 | RNA binding motif protein 25 | 0.0243088 |
| ATP2A2 | ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 | 0.0242243 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | 0.0242186 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TMSB10 | thymosin beta 10 | -0.19223 |
| PTMA | prothymosin, alpha | -0.16018 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.150311 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.135891 |
| FTL | ferritin, light polypeptide | -0.120239 |
| S100A6 | S100 calcium binding protein A6 | -0.107293 |
| S100A10 | S100 calcium binding protein A10 | -0.0975013 |
| RPL35A | ribosomal protein L35a | -0.0854744 |
| ACTG1 | actin gamma 1 | -0.0838683 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0791887 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0756409 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0751898 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0743329 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0723649 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0723647 |
| TMSB4X | thymosin beta 4, X-linked | -0.0718626 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0706756 |
| CCND1 | cyclin D1 | -0.0639124 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0633492 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0625725 |
| RPL34 | ribosomal protein L34 | -0.0611556 |
| LAMB3 | laminin, beta 3 | -0.0602018 |
| CD2AP | CD2-associated protein | -0.0598449 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0596365 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0592505 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.0582652 |
| RPL23 | ribosomal protein L23 | -0.055627 |
| CSTB | cystatin B (stefin B) | -0.0533684 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0481109 |
| TMEM123 | transmembrane protein 123 | -0.0480945 |
| GNAS | GNAS complex locus | -0.0476244 |
| RPS24 | ribosomal protein S24 | -0.0476008 |
| C15ORF48 | chromosome 15 open reading frame 48 | -0.0472305 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0465808 |
| RPLP1 | ribosomal protein, large, P1 | -0.0458221 |
| LMO7 | LIM domain 7 | -0.0444946 |
| MT2A | metallothionein 2A | -0.0440041 |
| RPLP2 | ribosomal protein, large, P2 | -0.0439382 |
| FN1 | fibronectin 1 | -0.0426047 |
| PGK1 | phosphoglycerate kinase 1 | -0.0422722 |
| LY6E | lymphocyte antigen 6 complex, locus E | -0.0418171 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0408303 |
| RPS19 | ribosomal protein S19 | -0.0406573 |
| FBXO32 | F-box protein 32 | -0.0400357 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.0397461 |
| VIM | vimentin | -0.0395579 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.0383153 |
| RPS13 | ribosomal protein S13 | -0.0371359 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0364891 |
| CD63 | CD63 molecule | -0.0360435 |
| RPLP0 | ribosomal protein, large, P0 | -0.0355453 |
| RPS25 | ribosomal protein S25 | -0.0353512 |
| FAM162A | family with sequence similarity 162, member A | -0.0351791 |
| KRT7 | keratin 7, type II | -0.0351212 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0350957 |
| LAMC2 | laminin, gamma 2 | -0.034485 |
| RPS23 | ribosomal protein S23 | -0.0340986 |
| MDK | midkine (neurite growth-promoting factor 2) | -0.0336192 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0331015 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0330937 |
| ARF1 | ADP-ribosylation factor 1 | -0.0330699 |
| RPL8 | ribosomal protein L8 | -0.0327406 |
| H1-0 | H1.0 linker histone | -0.0323436 |
| RPS21 | ribosomal protein S21 | -0.0316191 |
| CAVIN1 | caveolae associated protein 1 | -0.031521 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0314079 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0310954 |
| RPS14 | ribosomal protein S14 | -0.031076 |
| KRT18 | keratin 18, type I | -0.0307481 |
| RPL12 | ribosomal protein L12 | -0.0305852 |
| CTSB | cathepsin B | -0.030271 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0302168 |
| RPS29 | ribosomal protein S29 | -0.0301026 |
| ANXA2 | annexin A2 | -0.0300438 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0298019 |
| HLA-E | major histocompatibility complex, class I, E | -0.0293668 |
| RPL32 | ribosomal protein L32 | -0.0291713 |
| BZW1 | basic leucine zipper and W2 domains 1 | -0.0291236 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0291236 |
| NPC2 | Niemann-Pick disease, type C2 | -0.0288714 |
| TPM4 | tropomyosin 4 | -0.0288121 |
| SACK1A | scaffolding CK1 anchoring protein A | -0.0286813 |
| RPL19 | ribosomal protein L19 | -0.0282789 |
| RPS8 | ribosomal protein S8 | -0.0279137 |
| HLA-B | major histocompatibility complex, class I, B | -0.0276939 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | -0.0276283 |
| H3-3B | H3.3 histone B | -0.0275702 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | -0.0271686 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0271595 |
| MYL12B | myosin, light chain 12B, regulatory | -0.027133 |
| CTSD | cathepsin D | -0.0270625 |
| HMGA1 | high mobility group AT-hook 1 | -0.02679 |
| RPL36A | ribosomal protein L36a | -0.026756 |
| ZNF217 | zinc finger protein 217 | -0.0266073 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0259826 |
| RPS27A | ribosomal protein S27a | -0.0259746 |
| KRT19 | keratin 19, type I | -0.025906 |
| RPL38 | ribosomal protein L38 | -0.0256403 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0254803 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0254611 |
