| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Cloxacillin (sodium) perturbation in NCI-H460 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Cloxacillin (sodium)_NCI-H460 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0773595 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0568653 |
| DST | dystonin | 0.0515302 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0472922 |
| MT2A | metallothionein 2A | 0.042901 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0381424 |
| GRAMD1B | GRAM domain containing 1B | 0.0380614 |
| MAML3 | mastermind-like 3 (Drosophila) | 0.0362803 |
| SMOC1 | SPARC related modular calcium binding 1 | 0.0353065 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0335349 |
| PRELID2 | PRELI domain containing 2 | 0.0322591 |
| HDAC4 | histone deacetylase 4 | 0.0320087 |
| AUTS2 | autism susceptibility candidate 2 | 0.0301967 |
| PDE10A | phosphodiesterase 10A | 0.0296726 |
| INTS6 | integrator complex subunit 6 | 0.0287496 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0281702 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0275567 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0274621 |
| SMAD2 | SMAD family member 2 | 0.0274198 |
| DENND1A | DENN/MADD domain containing 1A | 0.0262184 |
| CTBP2 | C-terminal binding protein 2 | 0.024947 |
| OXSR1 | oxidative stress responsive 1 | 0.0244429 |
| FLNB | filamin B, beta | 0.0243629 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0243018 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | 0.0239239 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0238172 |
| CHL1 | cell adhesion molecule L1-like | 0.0237229 |
| FMNL2 | formin-like 2 | 0.0221205 |
| CTIF | CBP80/20-dependent translation initiation factor | 0.0216162 |
| MT1X | metallothionein 1X | 0.021144 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.0211242 |
| EZR | ezrin | 0.0209964 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0208334 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0193946 |
| ZNF638 | zinc finger protein 638 | 0.0192145 |
| GLRX | glutaredoxin (thioltransferase) | 0.0181792 |
| FAM219A | family with sequence similarity 219, member A | 0.0176191 |
| FNIP1 | folliculin interacting protein 1 | 0.0170429 |
| FBXL17 | F-box and leucine-rich repeat protein 17 | 0.0167098 |
| PYGL | phosphorylase, glycogen, liver | 0.0165605 |
| ARHGEF10 | Rho guanine nucleotide exchange factor (GEF) 10 | 0.0163145 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0161986 |
| PRKCA | protein kinase C, alpha | 0.0157468 |
| EXOC6B | exocyst complex component 6B | 0.0152841 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0151516 |
| CREB3L2 | cAMP responsive element binding protein 3-like 2 | 0.0149292 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0149008 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | 0.0148416 |
| MAP7 | microtubule-associated protein 7 | 0.0145241 |
| PDIA4 | protein disulfide isomerase family A, member 4 | 0.0144884 |
| RASAL2 | RAS protein activator like 2 | 0.0143946 |
| ADGRD1 | adhesion G protein-coupled receptor D1 | 0.0141857 |
| ABL1 | ABL proto-oncogene 1, non-receptor tyrosine kinase | 0.0141678 |
| PDGFA | platelet-derived growth factor alpha polypeptide | 0.0140116 |
| BMP6 | bone morphogenetic protein 6 | 0.0138137 |
| AHNAK | AHNAK nucleoprotein | 0.0137043 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0136753 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0133492 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0131595 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0131197 |
| ACVR1 | activin A receptor, type I | 0.0130695 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0128825 |
| ANKRD36 | ankyrin repeat domain 36 | 0.0127455 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.0127122 |
| PPFIA4 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4 | 0.0123818 |
| DTNA | dystrobrevin, alpha | 0.0121252 |
| AGTPBP1 | ATP/GTP binding protein 1 | 0.0120888 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0120704 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | 0.0119611 |
| GPC5 | glypican 5 | 0.0118124 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0117513 |
| PCSK5 | proprotein convertase subtilisin/kexin type 5 | 0.0115412 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0114665 |
| GMDS | GDP-mannose 4,6-dehydratase | 0.011397 |
| TUT7 | terminal uridylyl transferase 7 | 0.0113941 |
| MAFK | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog K | 0.0112919 |
| NBEAL1 | neurobeachin-like 1 | 0.0112706 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0112246 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0112076 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0111802 |
| ATXN2 | ataxin 2 | 0.0111034 |
| SVIL | supervillin | 0.0110871 |
| UHMK1 | U2AF homology motif (UHM) kinase 1 | 0.0108103 |
| ARB2A | ARB2 cotranscriptional regulator A | 0.0108038 |
| CYTH1 | cytohesin 1 | 0.0106054 |
| DIP2C | DIP2 disco-interacting protein 2 homolog C (Drosophila) | 0.0105834 |
| DISP1 | dispatched homolog 1 (Drosophila) | 0.0104914 |
| BTBD9 | BTB (POZ) domain containing 9 | 0.0103621 |
| NPAS2 | neuronal PAS domain protein 2 | 0.010155 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0101481 |
| GALNT2 | polypeptide N-acetylgalactosaminyltransferase 2 | 0.010057 |
| XYLT1 | xylosyltransferase I | 0.0100248 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0100232 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.00997103 |
| FAM117B | family with sequence similarity 117, member B | 0.00992046 |
| CACNA2D3 | calcium channel, voltage-dependent, alpha 2/delta subunit 3 | 0.00990538 |
| ATP9B | ATPase, class II, type 9B | 0.0097981 |
| KDM4C | lysine (K)-specific demethylase 4C | 0.00977258 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0097007 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | 0.00968392 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | -0.12931 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.112308 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.107694 |
| COL5A2 | collagen, type V, alpha 2 | -0.099879 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0883531 |
| VIM | vimentin | -0.0860696 |
| NRCAM | neuronal cell adhesion molecule | -0.0795302 |
| ASPH | aspartate beta-hydroxylase | -0.0741717 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0724539 |
| PTMA | prothymosin, alpha | -0.0717841 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0639459 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0631026 |
| SLC7A2 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 | -0.062043 |
| SLC39A8 | solute carrier family 39 (zinc transporter), member 8 | -0.0587996 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0577249 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0575584 |
| SMYD3 | SET and MYND domain containing 3 | -0.0548283 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.052654 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0515632 |
| PGK1 | phosphoglycerate kinase 1 | -0.048725 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0480414 |
| CD109 | CD109 molecule | -0.0479589 |
| CENPF | centromere protein F, 350/400kDa | -0.0473318 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.046404 |
| HLA-B | major histocompatibility complex, class I, B | -0.044558 |
| RPS24 | ribosomal protein S24 | -0.044486 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0431756 |
| B2M | beta-2-microglobulin | -0.0419926 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | -0.0406393 |
| ENO1 | enolase 1, (alpha) | -0.0402726 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0399635 |
| RPS8 | ribosomal protein S8 | -0.0394712 |
| TXNRD1 | thioredoxin reductase 1 | -0.0394303 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0389367 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0386079 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0384361 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.038387 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | -0.0383694 |
| RPL37A | ribosomal protein L37a | -0.0378138 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0367867 |
| SPAG9 | sperm associated antigen 9 | -0.0364169 |
| GDA | guanine deaminase | -0.0358349 |
| DPP10 | dipeptidyl-peptidase 10 (non-functional) | -0.033588 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | -0.0335495 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0329062 |
| RPL9 | ribosomal protein L9 | -0.0328776 |
| GNAS | GNAS complex locus | -0.0328574 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | -0.0308075 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0307877 |
| RPL35A | ribosomal protein L35a | -0.0305728 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | -0.0304516 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | -0.0299865 |
| RPS12 | ribosomal protein S12 | -0.0294866 |
| SRGN | serglycin | -0.0293084 |
| RPS3 | ribosomal protein S3 | -0.0292897 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | -0.0291118 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0289644 |
| LDHA | lactate dehydrogenase A | -0.0284579 |
| RPS27A | ribosomal protein S27a | -0.0284168 |
| STC1 | stanniocalcin 1 | -0.0281729 |
| RPL34 | ribosomal protein L34 | -0.0279734 |
| PRSS23 | protease, serine, 23 | -0.0278159 |
| TMSB10 | thymosin beta 10 | -0.0277676 |
| CTSC | cathepsin C | -0.0276838 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0271924 |
| RPL26 | ribosomal protein L26 | -0.02647 |
| CDH13 | cadherin 13 | -0.0264397 |
| BZW1 | basic leucine zipper and W2 domains 1 | -0.0260863 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0259783 |
| COL8A1 | collagen, type VIII, alpha 1 | -0.0259714 |
| SCN3A | sodium channel, voltage gated, type III alpha subunit | -0.0257263 |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 | -0.0256788 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0255617 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0254689 |
| OASL | 2'-5'-oligoadenylate synthetase-like | -0.0253364 |
| TPI1 | triosephosphate isomerase 1 | -0.0253116 |
| CTSL | cathepsin L | -0.0247423 |
| ATAD1 | ATPase family, AAA domain containing 1 | -0.024435 |
| PALLD | palladin, cytoskeletal associated protein | -0.0243379 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0241255 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0240131 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.023997 |
| RPL11 | ribosomal protein L11 | -0.0238616 |
| RPL36A | ribosomal protein L36a | -0.0235933 |
| PRKD3 | protein kinase D3 | -0.0235327 |
| ANK3 | ankyrin 3, node of Ranvier (ankyrin G) | -0.0234179 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0233774 |
| RGS2 | regulator of G-protein signaling 2 | -0.0232906 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0232504 |
| HLA-A | major histocompatibility complex, class I, A | -0.0231698 |
| RPL31 | ribosomal protein L31 | -0.0230608 |
| SLC2A13 | solute carrier family 2 (facilitated glucose transporter), member 13 | -0.0229679 |
| MKI67 | marker of proliferation Ki-67 | -0.0229339 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0228941 |
| S100A6 | S100 calcium binding protein A6 | -0.0222618 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.022062 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0215491 |
| PCBP3 | poly(rC) binding protein 3 | -0.0213153 |
| ZEB2 | zinc finger E-box binding homeobox 2 | -0.0211562 |
| ANXA2 | annexin A2 | -0.0205816 |
