| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Cloxacillin (sodium) perturbation in NCI-H661 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Cloxacillin (sodium)_NCI-H661 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| TSC22D2 | TSC22 domain family, member 2 | 0.0754099 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0549072 |
| PEG10 | paternally expressed 10 | 0.0543667 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | 0.0524031 |
| SUPT5H | suppressor of Ty 5 homolog (S. cerevisiae) | 0.0483367 |
| PTK2 | protein tyrosine kinase 2 | 0.0477875 |
| APP | amyloid beta (A4) precursor protein | 0.0473542 |
| VAPA | VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa | 0.0473042 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0467038 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0462886 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0459723 |
| QKI | QKI, KH domain containing, RNA binding | 0.0459625 |
| PUM1 | pumilio RNA-binding family member 1 | 0.0456017 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0412806 |
| SRP54 | signal recognition particle 54kDa | 0.0406322 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0402132 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0390412 |
| TLK1 | tousled-like kinase 1 | 0.0381815 |
| CALR | calreticulin | 0.0378227 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0371434 |
| NCKAP1 | NCK-associated protein 1 | 0.0369227 |
| RLF | rearranged L-myc fusion | 0.0365207 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0362723 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0355921 |
| MEMO1 | mediator of cell motility 1 | 0.0355113 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0354219 |
| ZNF292 | zinc finger protein 292 | 0.0347341 |
| PPP4R1 | protein phosphatase 4, regulatory subunit 1 | 0.0343173 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0335266 |
| YAP1 | Yes-associated protein 1 | 0.0332082 |
| CECR2 | cat eye syndrome chromosome region, candidate 2 | 0.0331012 |
| FAF1 | Fas (TNFRSF6) associated factor 1 | 0.033032 |
| MYO10 | myosin X | 0.032248 |
| SOX5 | SRY (sex determining region Y)-box 5 | 0.0321297 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0312928 |
| DST | dystonin | 0.0308814 |
| TBC1D12 | TBC1 domain family, member 12 | 0.0305561 |
| CDC73 | cell division cycle 73 | 0.030385 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.030245 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0302361 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0298699 |
| FMNL2 | formin-like 2 | 0.0293937 |
| PUM2 | pumilio RNA-binding family member 2 | 0.029099 |
| MEF2A | myocyte enhancer factor 2A | 0.0289194 |
| JMJD1C | jumonji domain containing 1C | 0.0288757 |
| MRPS30 | mitochondrial ribosomal protein S30 | 0.0288717 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0284699 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0277608 |
| MED13L | mediator complex subunit 13-like | 0.0276892 |
| PARD3 | par-3 family cell polarity regulator | 0.0273071 |
| SRPK2 | SRSF protein kinase 2 | 0.0269686 |
| POLR2B | polymerase (RNA) II (DNA directed) polypeptide B, 140kDa | 0.0268929 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | 0.0263907 |
| USP3 | ubiquitin specific peptidase 3 | 0.0263799 |
| ACTR3 | ARP3 actin-related protein 3 homolog (yeast) | 0.026371 |
| NEK7 | NIMA-related kinase 7 | 0.0260799 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0258408 |
| RYBP | RING1 and YY1 binding protein | 0.025599 |
| H1-0 | H1.0 linker histone | 0.0255075 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | 0.0254695 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0247977 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0246271 |
| WDR43 | WD repeat domain 43 | 0.0242668 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.0240619 |
| ERBIN | erbb2 interacting protein | 0.0240484 |
| EVI5 | ecotropic viral integration site 5 | 0.0239558 |
| SBF2 | SET binding factor 2 | 0.0237122 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0235718 |
| SMG7 | SMG7 nonsense mediated mRNA decay factor | 0.0235539 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0234547 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | 0.0233193 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | 0.0231731 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | 0.0229539 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0229168 |
| PCBP2 | poly(rC) binding protein 2 | 0.0226639 |
| OPHN1 | oligophrenin 1 | 0.0226626 |
| CDC50A | cell division cycle 50 P4-ATPase accessory subunit A | 0.0225778 |
| TPM3 | tropomyosin 3 | 0.0225515 |
| RHEB | Ras homolog enriched in brain | 0.022546 |
| ADGRB3 | adhesion G protein-coupled receptor B3 | 0.0224984 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | 0.0224243 |
| YTHDC1 | YTH domain containing 1 | 0.0223474 |
| PPP1CB | protein phosphatase 1, catalytic subunit, beta isozyme | 0.0222398 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | 0.0221997 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0220251 |
| MATR3 | matrin 3 | 0.0219017 |
| WASL | Wiskott-Aldrich syndrome-like | 0.0218617 |
| CARD16 | caspase recruitment domain family, member 16 | 0.0217364 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0215207 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0210586 |
| HAPSTR1 | HUWE1 associated protein modifying stress responses | 0.020973 |
| MBIP | MAP3K12 binding inhibitory protein 1 | 0.0208515 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0208287 |
| TENT2 | terminal nucleotidyltransferase 2 | 0.0208278 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0207457 |
| FBXO11 | F-box protein 11 | 0.0207247 |
| PAPOLA | poly(A) polymerase alpha | 0.0207207 |
| RPL3 | ribosomal protein L3 | 0.0206993 |
| NOP58 | NOP58 ribonucleoprotein | 0.0206887 |
| EPB41L3 | erythrocyte membrane protein band 4.1-like 3 | 0.0206887 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.228759 |
| ERBB4 | erb-b2 receptor tyrosine kinase 4 | -0.179449 |
| CADM2 | cell adhesion molecule 2 | -0.134475 |
| COL5A2 | collagen, type V, alpha 2 | -0.133663 |
| CDH6 | cadherin 6, type 2, K-cadherin (fetal kidney) | -0.126335 |
| PCDH9 | protocadherin 9 | -0.11267 |
| CTNNA3 | catenin (cadherin-associated protein), alpha 3 | -0.112634 |
| TMSB10 | thymosin beta 10 | -0.105846 |
| COL11A1 | collagen, type XI, alpha 1 | -0.0985529 |
| PCLO | piccolo presynaptic cytomatrix protein | -0.095325 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0910425 |
| VIM | vimentin | -0.0906636 |
| ADGRL2 | adhesion G protein-coupled receptor L2 | -0.0899157 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0883738 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | -0.0764156 |
| HS3ST5 | heparan sulfate (glucosamine) 3-O-sulfotransferase 5 | -0.0740136 |
| NRG1 | neuregulin 1 | -0.0669778 |
| GPC3 | glypican 3 | -0.0662162 |
| SLIT2 | slit homolog 2 (Drosophila) | -0.0598804 |
| PLPP1 | phospholipid phosphatase 1 | -0.0577808 |
| RPS8 | ribosomal protein S8 | -0.0563693 |
| PCDH7 | protocadherin 7 | -0.0554876 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0545861 |
| ADGRV1 | adhesion G protein-coupled receptor V1 | -0.0529202 |
| CDH10 | cadherin 10, type 2 (T2-cadherin) | -0.050396 |
| CTNNA2 | catenin (cadherin-associated protein), alpha 2 | -0.0502247 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0496759 |
| TRPS1 | trichorhinophalangeal syndrome I | -0.0494997 |
| RAD51B | RAD51 paralog B | -0.0480304 |
| ADGRL3 | adhesion G protein-coupled receptor L3 | -0.0477395 |
| MKI67 | marker of proliferation Ki-67 | -0.0470695 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0460572 |
| BMPR1A | bone morphogenetic protein receptor, type IA | -0.0452168 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | -0.043499 |
| MPG | N-methylpurine-DNA glycosylase | -0.0428166 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | -0.0425808 |
| COLGALT2 | collagen beta(1-O)galactosyltransferase 2 | -0.0422769 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0420835 |
| ARHGAP15 | Rho GTPase activating protein 15 | -0.0420327 |
| METAP2 | methionyl aminopeptidase 2 | -0.039873 |
| NHSL1 | NHS-like 1 | -0.0395828 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0394063 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0385143 |
| CSMD3 | CUB and Sushi multiple domains 3 | -0.0384612 |
| COL1A2 | collagen, type I, alpha 2 | -0.038257 |
| ACTG1 | actin gamma 1 | -0.0377473 |
| PARD3B | par-3 family cell polarity regulator beta | -0.037694 |
| CENPF | centromere protein F, 350/400kDa | -0.0375153 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.037359 |
| PGAP1 | post-GPI attachment to proteins 1 | -0.0370679 |
| HCN1 | hyperpolarization activated cyclic nucleotide gated potassium channel 1 | -0.0370139 |
| MEIS2 | Meis homeobox 2 | -0.036871 |
| BACH2 | BTB and CNC homology 1, basic leucine zipper transcription factor 2 | -0.0362096 |
| DOCK5 | dedicator of cytokinesis 5 | -0.0360509 |
| TENM3 | teneurin transmembrane protein 3 | -0.0357488 |
| RPL35A | ribosomal protein L35a | -0.0346564 |
| PHIP | pleckstrin homology domain interacting protein | -0.0339721 |
| SCFD1 | sec1 family domain containing 1 | -0.0326749 |
| TEX11 | testis expressed 11 | -0.0323673 |
| NEBL | nebulette | -0.0318588 |
| CKAP2 | cytoskeleton associated protein 2 | -0.031782 |
| TPX2 | TPX2, microtubule-associated | -0.0314612 |
| HMCN1 | hemicentin 1 | -0.03132 |
| ZFPM2 | zinc finger protein, FOG family member 2 | -0.0311892 |
| DARS1 | aspartyl-tRNA synthetase 1 | -0.0311058 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0310383 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0308226 |
| FST | follistatin | -0.029516 |
| MDK | midkine (neurite growth-promoting factor 2) | -0.0290682 |
| HS6ST2 | heparan sulfate 6-O-sulfotransferase 2 | -0.0290448 |
| RPL19 | ribosomal protein L19 | -0.0287884 |
| MEF2C | myocyte enhancer factor 2C | -0.0283874 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0283426 |
| RPL23 | ribosomal protein L23 | -0.0279286 |
| HMGB1 | high mobility group box 1 | -0.0274724 |
| CENPE | centromere protein E, 312kDa | -0.0274386 |
| PRELID2 | PRELI domain containing 2 | -0.0268249 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | -0.0268181 |
| CDH19 | cadherin 19, type 2 | -0.0266359 |
| ITGAV | integrin, alpha V | -0.0262912 |
| RPS27A | ribosomal protein S27a | -0.0258347 |
| RPL31 | ribosomal protein L31 | -0.0257503 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0256545 |
| ZEB2 | zinc finger E-box binding homeobox 2 | -0.0249786 |
| ARHGAP24 | Rho GTPase activating protein 24 | -0.0249401 |
| SFRP4 | secreted frizzled-related protein 4 | -0.024675 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0244631 |
| SON | SON DNA binding protein | -0.0244598 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | -0.0244366 |
| FILIP1 | filamin A interacting protein 1 | -0.0240413 |
| RAI1 | retinoic acid induced 1 | -0.0239048 |
| SEMA3D | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D | -0.023663 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0235844 |
| NPAS3 | neuronal PAS domain protein 3 | -0.0234709 |
| FTL | ferritin, light polypeptide | -0.0234298 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein | -0.0230058 |
| SCMH1 | sex comb on midleg homolog 1 (Drosophila) | -0.0229143 |
| SGO2 | shugoshin 2 | -0.0228166 |
| PHACTR4 | phosphatase and actin regulator 4 | -0.0227732 |
| SHROOM3 | shroom family member 3 | -0.0227326 |
