| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Cloxacillin (sodium) perturbation in PANC-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Cloxacillin (sodium)_PANC-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.133718 |
| SUPT5H | suppressor of Ty 5 homolog (S. cerevisiae) | 0.122448 |
| FBL | fibrillarin | 0.110075 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.108986 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0943409 |
| ZFP36 | ZFP36 ring finger protein | 0.0897703 |
| SAMD4B | sterile alpha motif domain containing 4B | 0.0832011 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0800058 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.079469 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0761319 |
| AHNAK | AHNAK nucleoprotein | 0.072829 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0711526 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.067987 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0653367 |
| BRD2 | bromodomain containing 2 | 0.0635404 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.063175 |
| INTS6 | integrator complex subunit 6 | 0.0607071 |
| YBX1 | Y box binding protein 1 | 0.0606039 |
| AKT2 | v-akt murine thymoma viral oncogene homolog 2 | 0.0601508 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0570809 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0570428 |
| CTBP2 | C-terminal binding protein 2 | 0.0569788 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0546135 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0537294 |
| SEPTIN9 | septin 9 | 0.053242 |
| CANX | calnexin | 0.052833 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.052814 |
| VEGFA | vascular endothelial growth factor A | 0.0504033 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0499435 |
| PCBP2 | poly(rC) binding protein 2 | 0.0495159 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.049255 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0489386 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0479508 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0477743 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0466179 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.046585 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0456532 |
| ZNF638 | zinc finger protein 638 | 0.0451584 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0438281 |
| NUP98 | nucleoporin 98kDa | 0.0435611 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0426586 |
| ENO1 | enolase 1, (alpha) | 0.0424187 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0422226 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0416439 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0413218 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0403904 |
| UBC | ubiquitin C | 0.0390303 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0389456 |
| PTK2 | protein tyrosine kinase 2 | 0.038556 |
| COPA | coatomer protein complex, subunit alpha | 0.0381927 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0379495 |
| ADM | adrenomedullin | 0.0379007 |
| RPL3 | ribosomal protein L3 | 0.0376036 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | 0.0372515 |
| SET | SET nuclear proto-oncogene | 0.0366116 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0359745 |
| CARS1 | cysteinyl-tRNA synthetase 1 | 0.0359161 |
| MSN | moesin | 0.0355012 |
| PKM | pyruvate kinase, muscle | 0.0354443 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0350826 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | 0.0347068 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0343775 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.0342271 |
| TPM3 | tropomyosin 3 | 0.0340721 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0336566 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0332832 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0331091 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0330837 |
| H1-0 | H1.0 linker histone | 0.032819 |
| MTHFD2 | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase | 0.0327299 |
| ERBIN | erbb2 interacting protein | 0.0318014 |
| RPS2 | ribosomal protein S2 | 0.0317073 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0309256 |
| DENND5A | DENN/MADD domain containing 5A | 0.0306332 |
| GOLGB1 | golgin B1 | 0.0306278 |
| PUM1 | pumilio RNA-binding family member 1 | 0.030604 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.030596 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0304782 |
| WNK1 | WNK lysine deficient protein kinase 1 | 0.0304054 |
| HYOU1 | hypoxia up-regulated 1 | 0.0302969 |
| LARS1 | leucyl-tRNA synthetase 1 | 0.0298774 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0298695 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.029594 |
| CDK13 | cyclin-dependent kinase 13 | 0.0294759 |
| TLN1 | talin 1 | 0.0292758 |
| RAB3GAP1 | RAB3 GTPase activating protein subunit 1 (catalytic) | 0.0290473 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0289812 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0286354 |
| BRD4 | bromodomain containing 4 | 0.0285594 |
| SQSTM1 | sequestosome 1 | 0.028412 |
| CALR | calreticulin | 0.0279914 |
| ANO6 | anoctamin 6 | 0.0279882 |
| PAF1 | Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae) | 0.0279617 |
| MAP1B | microtubule-associated protein 1B | 0.0278863 |
| SFTPA2 | surfactant protein A2 | 0.0278415 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0278222 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0276909 |
| ATF3 | activating transcription factor 3 | 0.0276587 |
| PIK3R3 | phosphoinositide-3-kinase, regulatory subunit 3 (gamma) | 0.0276021 |
| FMNL2 | formin-like 2 | 0.027578 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.20797 |
| CD44 | CD44 molecule (Indian blood group) | -0.117398 |
| TMSB10 | thymosin beta 10 | -0.0855095 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0813793 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | -0.0811599 |
| RPS16 | ribosomal protein S16 | -0.0700682 |
| ACTN4 | actinin, alpha 4 | -0.0627461 |
| RPS24 | ribosomal protein S24 | -0.0611343 |
| TMEM123 | transmembrane protein 123 | -0.0598374 |
| ACTG1 | actin gamma 1 | -0.0581011 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0579894 |
| RTN4 | reticulon 4 | -0.0545725 |
| RPL35A | ribosomal protein L35a | -0.0528992 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0511538 |
| CARD18 | caspase recruitment domain family, member 18 | -0.0499669 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0484121 |
| MT2A | metallothionein 2A | -0.0459114 |
| KLF6 | Kruppel-like factor 6 | -0.0459076 |
| ANXA2 | annexin A2 | -0.0458999 |
| GCNT2 | glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group) | -0.0453192 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0417544 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0372842 |
| BMAL2 | basic helix-loop-helix ARNT like 2 | -0.0365479 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | -0.0355422 |
| TMEM41B | transmembrane protein 41B | -0.0355168 |
| DHX32 | DEAH (Asp-Glu-Ala-His) box polypeptide 32 | -0.035135 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.0339535 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0334064 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | -0.0331978 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0327297 |
| FHL2 | four and a half LIM domains 2 | -0.0324431 |
| WWTR1 | WW domain containing transcription regulator 1 | -0.0323987 |
| SLC35F3 | solute carrier family 35, member F3 | -0.0322094 |
| SLC16A3 | solute carrier family 16 (monocarboxylate transporter), member 3 | -0.0319241 |
| ARHGAP29 | Rho GTPase activating protein 29 | -0.0317704 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0314361 |
| KLHL5 | kelch-like family member 5 | -0.0311593 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0310447 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | -0.0306807 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | -0.0304134 |
| RPLP2 | ribosomal protein, large, P2 | -0.0301141 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | -0.0297843 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.0292853 |
| EGFR | epidermal growth factor receptor | -0.0283432 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | -0.0281388 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0280855 |
| ITGB5 | integrin, beta 5 | -0.0278646 |
| EIF3K | eukaryotic translation initiation factor 3, subunit K | -0.027839 |
| TUBB | tubulin, beta class I | -0.0277826 |
| DDAH1 | dimethylarginine dimethylaminohydrolase 1 | -0.0276128 |
| ABLIM1 | actin binding LIM protein 1 | -0.0267482 |
| ERGIC1 | endoplasmic reticulum-golgi intermediate compartment (ERGIC) 1 | -0.02659 |
| PERP | PERP, TP53 apoptosis effector | -0.0262937 |
| MCTP1 | multiple C2 domains, transmembrane 1 | -0.0262875 |
| RAP1B | RAP1B, member of RAS oncogene family | -0.0260522 |
| SMYD3 | SET and MYND domain containing 3 | -0.0258816 |
| RPL36A | ribosomal protein L36a | -0.0253661 |
| ZNF217 | zinc finger protein 217 | -0.0253632 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0251965 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0251008 |
| DSTN | destrin (actin depolymerizing factor) | -0.0250351 |
| OSMR | oncostatin M receptor | -0.0248749 |
| ODF2L | outer dense fiber of sperm tails 2-like | -0.0248224 |
| IL6ST | interleukin 6 signal transducer | -0.0246027 |
| CBX3 | chromobox homolog 3 | -0.0244923 |
| EFNA5 | ephrin-A5 | -0.0242893 |
| EGR1 | early growth response 1 | -0.0241087 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | -0.024035 |
| SPRY4 | sprouty homolog 4 (Drosophila) | -0.0236948 |
| VCL | vinculin | -0.0236336 |
| S100A10 | S100 calcium binding protein A10 | -0.0236335 |
| SLC25A5 | solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5 | -0.023431 |
| CD59 | CD59 molecule, complement regulatory protein | -0.0233898 |
| RPS21 | ribosomal protein S21 | -0.0231709 |
| RPLP0 | ribosomal protein, large, P0 | -0.0229715 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0228556 |
| SYTL2 | synaptotagmin-like 2 | -0.0223769 |
| PLAC8 | placenta-specific 8 | -0.0222292 |
| CMSS1 | cms1 ribosomal small subunit homolog (yeast) | -0.0220174 |
| SMAD3 | SMAD family member 3 | -0.0219544 |
| F2RL1 | coagulation factor II (thrombin) receptor-like 1 | -0.0215196 |
| ANGPTL4 | angiopoietin-like 4 | -0.0215128 |
| CDCP1 | CUB domain containing protein 1 | -0.0214037 |
| IER3 | immediate early response 3 | -0.0211775 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.0211505 |
| PYGB | phosphorylase, glycogen; brain | -0.0210686 |
| ZNF292 | zinc finger protein 292 | -0.021058 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | -0.0209193 |
| UBASH3B | ubiquitin associated and SH3 domain containing B | -0.0206034 |
| CRYBG1 | crystallin beta-gamma domain containing 1 | -0.0205456 |
| PRSS23 | protease, serine, 23 | -0.0205255 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0204964 |
| CAPZA1 | capping protein (actin filament) muscle Z-line, alpha 1 | -0.0203623 |
| FAM3C | family with sequence similarity 3, member C | -0.0202518 |
| DNMBP | dynamin binding protein | -0.0200486 |
| C15ORF48 | chromosome 15 open reading frame 48 | -0.0198444 |
| FOSL1 | FOS-like antigen 1 | -0.0197239 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0197155 |
| RPL38 | ribosomal protein L38 | -0.019611 |
| CHCHD2 | coiled-coil-helix-coiled-coil-helix domain containing 2 | -0.0194823 |
