| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Cloxacillin (sodium) perturbation in Panc 03.27 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Cloxacillin (sodium)_Panc 03.27 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FNDC3B | fibronectin type III domain containing 3B | 0.0962696 |
| EZR | ezrin | 0.0823773 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0740386 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.072607 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0670219 |
| RPS6 | ribosomal protein S6 | 0.0666481 |
| NDRG1 | N-myc downstream regulated 1 | 0.0659753 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0656576 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0651215 |
| VEGFA | vascular endothelial growth factor A | 0.0619042 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.061577 |
| LMO7 | LIM domain 7 | 0.061066 |
| AHNAK | AHNAK nucleoprotein | 0.060703 |
| SQSTM1 | sequestosome 1 | 0.0584822 |
| CANX | calnexin | 0.0564988 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 | 0.0555073 |
| TXNIP | thioredoxin interacting protein | 0.0549787 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0541913 |
| FMNL2 | formin-like 2 | 0.0538376 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0527534 |
| PTMA | prothymosin, alpha | 0.0527376 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0527132 |
| DSPP | dentin sialophosphoprotein | 0.0525851 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0519292 |
| BRD2 | bromodomain containing 2 | 0.0512961 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0508217 |
| KDM5B | lysine (K)-specific demethylase 5B | 0.0499453 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0493255 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | 0.0491249 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | 0.0478953 |
| TMSB4X | thymosin beta 4, X-linked | 0.0470548 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0467365 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0458345 |
| PTK2 | protein tyrosine kinase 2 | 0.0456281 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0453991 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0449562 |
| ATF3 | activating transcription factor 3 | 0.0449243 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0445369 |
| NEDD9 | neural precursor cell expressed, developmentally down-regulated 9 | 0.0441056 |
| MYO5B | myosin VB | 0.0439194 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.043526 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0431038 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0422773 |
| NAV2 | neuron navigator 2 | 0.0421031 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.042099 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0420651 |
| ARHGEF3 | Rho guanine nucleotide exchange factor (GEF) 3 | 0.0419566 |
| RIMKLB | ribosomal modification protein rimK-like family member B | 0.0419459 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0413378 |
| PCBP2 | poly(rC) binding protein 2 | 0.0409871 |
| OXSR1 | oxidative stress responsive 1 | 0.0389844 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0388877 |
| LAMB3 | laminin, beta 3 | 0.038596 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0384047 |
| RNF213 | ring finger protein 213 | 0.0382553 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.0382151 |
| SDC4 | syndecan 4 | 0.0379404 |
| FN1 | fibronectin 1 | 0.0376574 |
| CD47 | CD47 molecule | 0.037524 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | 0.0365472 |
| FOXO3 | forkhead box O3 | 0.0362203 |
| H1-0 | H1.0 linker histone | 0.0355623 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0354293 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0353466 |
| TPM4 | tropomyosin 4 | 0.0351575 |
| PLAUR | plasminogen activator, urokinase receptor | 0.0348816 |
| CDYL | chromodomain protein, Y-like | 0.034791 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | 0.0347233 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.034669 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0344763 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.034429 |
| PKM | pyruvate kinase, muscle | 0.0343887 |
| OGA | O-GlcNAcase | 0.0341139 |
| BTBD9 | BTB (POZ) domain containing 9 | 0.0338455 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0338233 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0337661 |
| SET | SET nuclear proto-oncogene | 0.0334124 |
| SMAD3 | SMAD family member 3 | 0.0332853 |
| JMJD1C | jumonji domain containing 1C | 0.0329324 |
| XPO1 | exportin 1 | 0.032443 |
| KIAA1671 | KIAA1671 | 0.0321475 |
| RBM39 | RNA binding motif protein 39 | 0.0317437 |
| YAP1 | Yes-associated protein 1 | 0.0316507 |
| BBX | bobby sox homolog (Drosophila) | 0.0316248 |
| RPS12 | ribosomal protein S12 | 0.0314359 |
| TPM3 | tropomyosin 3 | 0.0313213 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | 0.03082 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | 0.0307049 |
| MYO6 | myosin VI | 0.0306684 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0305943 |
| AFDN | afadin, adherens junction formation factor | 0.0305466 |
| H2AC6 | H2A clustered histone 6 | 0.030534 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0303741 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0300128 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0299812 |
| ITGA6 | integrin, alpha 6 | 0.0299054 |
| CCNL1 | cyclin L1 | 0.0297622 |
| TMF1 | TATA element modulatory factor 1 | 0.0297529 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0295677 |
| SKAP2 | src kinase associated phosphoprotein 2 | 0.0294209 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.187948 |
| LAMA4 | laminin, alpha 4 | -0.117654 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0840211 |
| MUC4 | mucin 4, cell surface associated | -0.0783562 |
| VCL | vinculin | -0.072895 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0691002 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0668771 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | -0.0666708 |
| DIAPH3 | diaphanous-related formin 3 | -0.0605197 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0567477 |
| RASAL2 | RAS protein activator like 2 | -0.0543772 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0514283 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | -0.0486117 |
| WWC1 | WW and C2 domain containing 1 | -0.0480269 |
| TMSB10 | thymosin beta 10 | -0.0474601 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0459524 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | -0.0458788 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | -0.0456718 |
| OSMR | oncostatin M receptor | -0.0448188 |
| EGFR | epidermal growth factor receptor | -0.0445443 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0421429 |
| ARHGAP29 | Rho GTPase activating protein 29 | -0.0415477 |
| ECT2 | epithelial cell transforming 2 | -0.0404319 |
| SLC20A2 | solute carrier family 20 (phosphate transporter), member 2 | -0.0384503 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | -0.0381305 |
| DLC1 | DLC1 Rho GTPase activating protein | -0.0378746 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | -0.037426 |
| THBS1 | thrombospondin 1 | -0.037335 |
| EGR1 | early growth response 1 | -0.0360114 |
| MYOF | myoferlin | -0.0357309 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.0346551 |
| BCL2L1 | BCL2-like 1 | -0.0343868 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | -0.0335598 |
| MKI67 | marker of proliferation Ki-67 | -0.0320107 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0316775 |
| KRT18 | keratin 18, type I | -0.031138 |
| ANLN | anillin, actin binding protein | -0.0308954 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0298215 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0292697 |
| MT2A | metallothionein 2A | -0.0291762 |
| LDHA | lactate dehydrogenase A | -0.0284336 |
| PCLO | piccolo presynaptic cytomatrix protein | -0.0279386 |
| MUC16 | mucin 16, cell surface associated | -0.0274654 |
| MELTF | melanotransferrin | -0.0270776 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0268259 |
| RBMS2 | RNA binding motif, single stranded interacting protein 2 | -0.0264319 |
| ANKRD33B | ankyrin repeat domain 33B | -0.026362 |
| PLAT | plasminogen activator, tissue | -0.0258524 |
| RPS24 | ribosomal protein S24 | -0.0255054 |
| C6ORF132 | chromosome 6 open reading frame 132 | -0.0253528 |
| INHBA | inhibin, beta A | -0.0247849 |
| OSBPL3 | oxysterol binding protein-like 3 | -0.0244874 |
| ANXA3 | annexin A3 | -0.0244006 |
| S100A6 | S100 calcium binding protein A6 | -0.0235893 |
| TGFB2 | transforming growth factor, beta 2 | -0.0231517 |
| HS3ST1 | heparan sulfate (glucosamine) 3-O-sulfotransferase 1 | -0.0230589 |
| CENPF | centromere protein F, 350/400kDa | -0.0229062 |
| ENC1 | ectodermal-neural cortex 1 (with BTB domain) | -0.0228483 |
| HMGA1 | high mobility group AT-hook 1 | -0.0227968 |
| SPIDR | scaffolding protein involved in DNA repair | -0.022149 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | -0.0220969 |
| SHROOM3 | shroom family member 3 | -0.0219855 |
| ACTN4 | actinin, alpha 4 | -0.0218894 |
| TMEM123 | transmembrane protein 123 | -0.0217022 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.0216576 |
| H3-3B | H3.3 histone B | -0.0216152 |
| ANXA2 | annexin A2 | -0.0214216 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0213588 |
| MAL2 | mal, T-cell differentiation protein 2 (gene/pseudogene) | -0.0212584 |
| MIS18BP1 | MIS18 binding protein 1 | -0.0212526 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0208818 |
| IL1RAP | interleukin 1 receptor accessory protein | -0.0206487 |
| ADAMTS12 | ADAM metallopeptidase with thrombospondin type 1 motif, 12 | -0.0204422 |
| INTS6 | integrator complex subunit 6 | -0.020362 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | -0.0203172 |
| SENP5 | SUMO1/sentrin specific peptidase 5 | -0.0203089 |
| LY6E | lymphocyte antigen 6 complex, locus E | -0.0202862 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0202859 |
| UBASH3B | ubiquitin associated and SH3 domain containing B | -0.0201407 |
| FRMD6 | FERM domain containing 6 | -0.020095 |
| CDK6 | cyclin-dependent kinase 6 | -0.0200353 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0199724 |
| HLA-B | major histocompatibility complex, class I, B | -0.0196203 |
| NFIB | nuclear factor I/B | -0.0195468 |
| RHEB | Ras homolog enriched in brain | -0.0193202 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0186998 |
| STARD13 | StAR-related lipid transfer (START) domain containing 13 | -0.0186614 |
| NF1 | neurofibromin 1 | -0.018572 |
| SON | SON DNA binding protein | -0.0182013 |
| PRRG1 | proline rich Gla (G-carboxyglutamic acid) 1 | -0.0181249 |
| TACSTD2 | tumor-associated calcium signal transducer 2 | -0.0179913 |
| SCLT1 | sodium channel and clathrin linker 1 | -0.0179871 |
| HLA-C | major histocompatibility complex, class I, C | -0.017871 |
| ANKRD1 | ankyrin repeat domain 1 (cardiac muscle) | -0.0178063 |
| GRHL2 | grainyhead-like 2 (Drosophila) | -0.0173635 |
| PITPNB | phosphatidylinositol transfer protein, beta | -0.0173277 |
| METTL15 | methyltransferase like 15 | -0.0172194 |
| BRAF | B-Raf proto-oncogene, serine/threonine kinase | -0.0171616 |
| TUBB | tubulin, beta class I | -0.0170862 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0169114 |