| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Cloxacillin (sodium) perturbation in RPMI-7951 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Cloxacillin (sodium)_RPMI-7951 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0986513 |
| ASPH | aspartate beta-hydroxylase | 0.0836202 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0627954 |
| HMGA2 | high mobility group AT-hook 2 | 0.0422046 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0366804 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0366091 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0339683 |
| MCTP2 | multiple C2 domains, transmembrane 2 | 0.0330342 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0317505 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0297988 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.027266 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0272081 |
| PDE10A | phosphodiesterase 10A | 0.0267224 |
| CLIP4 | CAP-GLY domain containing linker protein family, member 4 | 0.0256566 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0254416 |
| BBS9 | Bardet-Biedl syndrome 9 | 0.0246182 |
| MMP12 | matrix metallopeptidase 12 | 0.0230982 |
| COL7A1 | collagen, type VII, alpha 1 | 0.0229139 |
| FNIP1 | folliculin interacting protein 1 | 0.022377 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0220507 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0215451 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0211431 |
| HPCAL1 | hippocalcin-like 1 | 0.0205756 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | 0.0203197 |
| LHFPL2 | lipoma HMGIC fusion partner-like 2 | 0.0200292 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | 0.0196576 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0193593 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0190655 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0187546 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0187504 |
| SKAP2 | src kinase associated phosphoprotein 2 | 0.0185341 |
| PLEKHA4 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 4 | 0.0184825 |
| SETBP1 | SET binding protein 1 | 0.0184728 |
| MMP24OS | MMP24 opposite strand | 0.0183318 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0179509 |
| HOOK3 | hook microtubule-tethering protein 3 | 0.0178275 |
| TRPC1 | transient receptor potential cation channel, subfamily C, member 1 | 0.0174114 |
| NBEA | neurobeachin | 0.0172211 |
| DDR2 | discoidin domain receptor tyrosine kinase 2 | 0.0171621 |
| ARHGAP22 | Rho GTPase activating protein 22 | 0.0167384 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | 0.0164448 |
| SEC61A1 | Sec61 alpha 1 subunit (S. cerevisiae) | 0.0163904 |
| TMEM178B | transmembrane protein 178B | 0.016274 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0162354 |
| TMEM14B | transmembrane protein 14B | 0.016084 |
| PAG1 | phosphoprotein membrane anchor with glycosphingolipid microdomains 1 | 0.0160439 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0159661 |
| ATM | ATM serine/threonine kinase | 0.0159611 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.015916 |
| FBXL2 | F-box and leucine-rich repeat protein 2 | 0.0157377 |
| PHC2 | polyhomeotic homolog 2 (Drosophila) | 0.0156155 |
| MYO1E | myosin IE | 0.015519 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | 0.0154591 |
| AEBP2 | AE binding protein 2 | 0.0153005 |
| EGFR | epidermal growth factor receptor | 0.014992 |
| INTS6 | integrator complex subunit 6 | 0.0149566 |
| RANBP2 | RAN binding protein 2 | 0.0148393 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0148256 |
| MAGED1 | melanoma antigen family D1 | 0.0147836 |
| KYNU | kynureninase | 0.0146449 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | 0.0146305 |
| AFF3 | AF4/FMR2 family, member 3 | 0.0145478 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | 0.0144067 |
| ZNF780B | zinc finger protein 780B | 0.0141091 |
| HDAC4 | histone deacetylase 4 | 0.0140725 |
| KIRREL1 | kirre like nephrin family adhesion molecule 1 | 0.0140507 |
| EIF2S2 | eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa | 0.0140332 |
| NCOA3 | nuclear receptor coactivator 3 | 0.0139274 |
| DIP2C | DIP2 disco-interacting protein 2 homolog C (Drosophila) | 0.0138738 |
| SHOC2 | soc-2 suppressor of clear homolog (C. elegans) | 0.0137603 |
| GPATCH2L | G patch domain containing 2-like | 0.013729 |
| RNF217 | ring finger protein 217 | 0.0135571 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0135384 |
| SHISA5 | shisa family member 5 | 0.0134787 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.0134111 |
| BPTF | bromodomain PHD finger transcription factor | 0.0133754 |
| FERMT2 | fermitin family member 2 | 0.0130938 |
| SUPT6H | suppressor of Ty 6 homolog (S. cerevisiae) | 0.0130692 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0129941 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.0129754 |
| PHF14 | PHD finger protein 14 | 0.0129722 |
| ST3GAL6 | ST3 beta-galactoside alpha-2,3-sialyltransferase 6 | 0.012908 |
| PER3 | period circadian clock 3 | 0.0128039 |
| EXOC4 | exocyst complex component 4 | 0.0127827 |
| AHNAK | AHNAK nucleoprotein | 0.0127427 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0126767 |
| LCORL | ligand dependent nuclear receptor corepressor-like | 0.0124308 |
| MNMIP1 | manchette microtubule inner protein 1 | 0.0123565 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | 0.0121995 |
| ZFYVE28 | zinc finger, FYVE domain containing 28 | 0.0121049 |
| OGDH | oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide) | 0.0120619 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | 0.0119724 |
| ARHGAP12 | Rho GTPase activating protein 12 | 0.0119048 |
| FBN1 | fibrillin 1 | 0.0119045 |
| SMAD2 | SMAD family member 2 | 0.0118835 |
| OGA | O-GlcNAcase | 0.0118272 |
| FAM177A1 | family with sequence similarity 177, member A1 | 0.0118108 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0117533 |
| GPR173 | G protein-coupled receptor 173 | 0.0116302 |
| CADM1 | cell adhesion molecule 1 | 0.0116271 |
| Symbol | Name | Standardized Value |
|---|---|---|
| COL1A1 | collagen, type I, alpha 1 | -0.178031 |
| FN1 | fibronectin 1 | -0.16695 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.165108 |
| STC1 | stanniocalcin 1 | -0.157737 |
| HLA-B | major histocompatibility complex, class I, B | -0.140493 |
| B2M | beta-2-microglobulin | -0.139852 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.137211 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.133511 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.13201 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.113408 |
| COL6A1 | collagen, type VI, alpha 1 | -0.108603 |
| NDRG1 | N-myc downstream regulated 1 | -0.103165 |
| CD44 | CD44 molecule (Indian blood group) | -0.0902844 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.0875836 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0875669 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0820968 |
| MT2A | metallothionein 2A | -0.0792238 |
| ZEB1 | zinc finger E-box binding homeobox 1 | -0.0762795 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0741923 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0704921 |
| COL6A2 | collagen, type VI, alpha 2 | -0.066477 |
| POTEF | POTE ankyrin domain family, member F | -0.063389 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.062648 |
| TNNC1 | troponin C type 1 (slow) | -0.0574509 |
| ZNF292 | zinc finger protein 292 | -0.0564558 |
| FRMD4A | FERM domain containing 4A | -0.0562555 |
| COL1A2 | collagen, type I, alpha 2 | -0.0527749 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.052353 |
| PTMA | prothymosin, alpha | -0.052319 |
| HLA-C | major histocompatibility complex, class I, C | -0.051888 |
| VIM | vimentin | -0.0483272 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0477787 |
| RBM39 | RNA binding motif protein 39 | -0.0474669 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0473374 |
| XPO1 | exportin 1 | -0.046914 |
| MYH9 | myosin, heavy chain 9, non-muscle | -0.0465268 |
| TMSB10 | thymosin beta 10 | -0.0460709 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | -0.045069 |
| ANXA2 | annexin A2 | -0.0442948 |
| CDH13 | cadherin 13 | -0.0442545 |
| CALU | calumenin | -0.0441076 |
| COL4A2 | collagen, type IV, alpha 2 | -0.043967 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | -0.0430581 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0421772 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0420005 |
| SP100 | SP100 nuclear antigen | -0.0418355 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | -0.0416844 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0414406 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0413921 |
| IER3 | immediate early response 3 | -0.0411308 |
| SEPTIN7 | septin 7 | -0.0401558 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0394714 |
| TPM4 | tropomyosin 4 | -0.0393572 |
| SAMD9 | sterile alpha motif domain containing 9 | -0.0377375 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0375937 |
| HLA-A | major histocompatibility complex, class I, A | -0.0373103 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0371647 |
| SPAG9 | sperm associated antigen 9 | -0.0370084 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0367312 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0366968 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0365546 |
| COL5A1 | collagen, type V, alpha 1 | -0.0362162 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.035978 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | -0.035749 |
| RPS6 | ribosomal protein S6 | -0.0355579 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0355516 |
| MX1 | MX dynamin-like GTPase 1 | -0.0354271 |
| ZBTB38 | zinc finger and BTB domain containing 38 | -0.0353494 |
| GOLGA4 | golgin A4 | -0.0350239 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0347985 |
| RYBP | RING1 and YY1 binding protein | -0.0347445 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0338323 |
| VCAN | versican | -0.0331902 |
| KIF5B | kinesin family member 5B | -0.0331139 |
| CTSB | cathepsin B | -0.0328224 |
| DDIT4 | DNA-damage-inducible transcript 4 | -0.0326856 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0323166 |
| ANGPTL4 | angiopoietin-like 4 | -0.032079 |
| MED13L | mediator complex subunit 13-like | -0.0319478 |
| IL1B | interleukin 1, beta | -0.0316468 |
| PKM | pyruvate kinase, muscle | -0.0315754 |
| LDHA | lactate dehydrogenase A | -0.031426 |
| TPM1 | tropomyosin 1 (alpha) | -0.0314176 |
| ANLN | anillin, actin binding protein | -0.0313037 |
| CDCP1 | CUB domain containing protein 1 | -0.0308591 |
| ADAR | adenosine deaminase, RNA-specific | -0.0308518 |
| TGM2 | transglutaminase 2 | -0.0306506 |
| TNS3 | tensin 3 | -0.0304187 |
| PTK2 | protein tyrosine kinase 2 | -0.0301689 |
| RPS2 | ribosomal protein S2 | -0.0300379 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0299372 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0298872 |
| DSTN | destrin (actin depolymerizing factor) | -0.0295654 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | -0.0294726 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0290988 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0290903 |
| RUNX1 | runt-related transcription factor 1 | -0.0290455 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0289636 |
| NCKAP1 | NCK-associated protein 1 | -0.0288441 |
| PEAK1 | pseudopodium-enriched atypical kinase 1 | -0.0288155 |