Cloxacillin (sodium)_SNU-1 Gene Set

Dataset Tahoe Therapeutics Tahoe 100M Perturbation Atlas
Category transcriptomics
Type cell type
Description Cloxacillin (sodium) perturbation in SNU-1 cell line (Tahoe Therapeutics)
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Genes

200 genes differentially expressed following the Cloxacillin (sodium)_SNU-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.

increased expression

Symbol Name Standardized Value
AHNAK AHNAK nucleoprotein 0.04594
ZEB1 zinc finger E-box binding homeobox 1 0.0326435
CRIM1 cysteine rich transmembrane BMP regulator 1 (chordin-like) 0.0256765
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) 0.0232846
ZNF608 zinc finger protein 608 0.0223736
DSCAM Down syndrome cell adhesion molecule 0.0211379
PDE4D phosphodiesterase 4D, cAMP-specific 0.0209163
EEF1A1 eukaryotic translation elongation factor 1 alpha 1 0.0203575
CAMTA1 calmodulin binding transcription activator 1 0.0193024
ZFAND3 zinc finger, AN1-type domain 3 0.0189094
SOX6 SRY (sex determining region Y)-box 6 0.0187415
ERO1A endoplasmic reticulum oxidoreductase 1 alpha 0.0184965
PDGFC platelet derived growth factor C 0.0180177
BMP2K BMP2 inducible kinase 0.0178271
HDAC9 histone deacetylase 9 0.0176497
MYOF myoferlin 0.0173632
EML4 echinoderm microtubule associated protein like 4 0.0159695
UBR5 ubiquitin protein ligase E3 component n-recognin 5 0.0155824
TJP1 tight junction protein 1 0.015534
ADAM10 ADAM metallopeptidase domain 10 0.0152256
RBM39 RNA binding motif protein 39 0.0149339
EVI5 ecotropic viral integration site 5 0.0144037
GLS2 glutaminase 2 (liver, mitochondrial) 0.0143821
TBL1XR1 transducin (beta)-like 1 X-linked receptor 1 0.0142043
SSBP2 single-stranded DNA binding protein 2 0.0139868
ANXA1 annexin A1 0.0139251
HSPA8 heat shock 70kDa protein 8 0.0133724
ASCC3 activating signal cointegrator 1 complex subunit 3 0.0132926
OGA O-GlcNAcase 0.0131678
PPP6R3 protein phosphatase 6, regulatory subunit 3 0.0127364
KMT2E lysine (K)-specific methyltransferase 2E 0.0127007
JMJD1C jumonji domain containing 1C 0.0126966
YAP1 Yes-associated protein 1 0.0123414
PRELID2 PRELI domain containing 2 0.0123252
KDM3A lysine (K)-specific demethylase 3A 0.0120437
RTN4 reticulon 4 0.0118988
PUM2 pumilio RNA-binding family member 2 0.0117863
APP amyloid beta (A4) precursor protein 0.0116097
SCD stearoyl-CoA desaturase (delta-9-desaturase) 0.0113666
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa 0.0113445
HELZ helicase with zinc finger 0.0111428
RLF rearranged L-myc fusion 0.0110227
NCEH1 neutral cholesterol ester hydrolase 1 0.0107807
CNOT6L CCR4-NOT transcription complex, subunit 6-like 0.0106209
PPP2R2A protein phosphatase 2, regulatory subunit B, alpha 0.0105937
CDC73 cell division cycle 73 0.0105455
SPTAN1 spectrin, alpha, non-erythrocytic 1 0.0105038
ATOSA atos homolog A 0.0104271
MED13L mediator complex subunit 13-like 0.0103022
TRPM7 transient receptor potential cation channel, subfamily M, member 7 0.0102953
ARIH1 ariadne RBR E3 ubiquitin protein ligase 1 0.0102765
KMT2C lysine (K)-specific methyltransferase 2C 0.0102586
EPS8 epidermal growth factor receptor pathway substrate 8 0.0101937
LPP LIM domain containing preferred translocation partner in lipoma 0.0100929
DYRK1A dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A 0.0100668
NCOA3 nuclear receptor coactivator 3 0.0100655
NCKAP1 NCK-associated protein 1 0.0100552
MACF1 microtubule-actin crosslinking factor 1 0.00995359
TSC22D2 TSC22 domain family, member 2 0.00974219
EIF4A2 eukaryotic translation initiation factor 4A2 0.00958105
XKR6 XK, Kell blood group complex subunit-related family, member 6 0.00955298
SAMD4A sterile alpha motif domain containing 4A 0.0095019
TMEM65 transmembrane protein 65 0.00945113
HIVEP2 human immunodeficiency virus type I enhancer binding protein 2 0.00942928
PDE4B phosphodiesterase 4B, cAMP-specific 0.00938878
XPO1 exportin 1 0.00936716
ZFC3H1 zinc finger, C3H1-type containing 0.0093523
NUP153 nucleoporin 153kDa 0.00909819
EXT1 exostosin glycosyltransferase 1 0.00909338
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase 0.00907084
KAT6A K(lysine) acetyltransferase 6A 0.00902275
QKI QKI, KH domain containing, RNA binding 0.00899269
PCNX1 pecanex 1 0.00897798
USP34 ubiquitin specific peptidase 34 0.00895211
DIP2C DIP2 disco-interacting protein 2 homolog C (Drosophila) 0.00894641
FMNL2 formin-like 2 0.00890334
CRY1 cryptochrome circadian clock 1 0.00885089
FAT1 FAT atypical cadherin 1 0.00880547
DENND5A DENN/MADD domain containing 5A 0.00879937
USP3 ubiquitin specific peptidase 3 0.00877653
EGLN1 egl-9 family hypoxia-inducible factor 1 0.00861452
WAC WW domain containing adaptor with coiled-coil 0.00861323
TFG TRK-fused gene 0.0085615
RBM33 RNA binding motif protein 33 0.0084917
ZNF638 zinc finger protein 638 0.00844989
ARID1A AT rich interactive domain 1A (SWI-like) 0.00843994
OGT O-linked N-acetylglucosamine (GlcNAc) transferase 0.00841104
TGFBR3 transforming growth factor, beta receptor III 0.00836335
ATP2C1 ATPase, Ca++ transporting, type 2C, member 1 0.00834492
CEP95 centrosomal protein 95kDa 0.00830419
BTAF1 BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa 0.00825326
KDM6A lysine (K)-specific demethylase 6A 0.00824181
ABCA5 ATP-binding cassette, sub-family A (ABC1), member 5 0.00822183
IGF1R insulin-like growth factor 1 receptor 0.0081867
TRIO trio Rho guanine nucleotide exchange factor 0.00817903
CHD7 chromodomain helicase DNA binding protein 7 0.00817737
ERBIN erbb2 interacting protein 0.0081596
TOP2B topoisomerase (DNA) II beta 180kDa 0.00815351
AUH AU RNA binding protein/enoyl-CoA hydratase 0.00811275
CORO1C coronin, actin binding protein, 1C 0.00810028

decreased expression

Symbol Name Standardized Value
GAPDH glyceraldehyde-3-phosphate dehydrogenase -0.199313
PTMA prothymosin, alpha -0.181701
TPT1 tumor protein, translationally-controlled 1 -0.0605153
RPS6 ribosomal protein S6 -0.0600965
RPS8 ribosomal protein S8 -0.0584416
RPL35A ribosomal protein L35a -0.0492763
RPL31 ribosomal protein L31 -0.0412397
RPLP1 ribosomal protein, large, P1 -0.0386569
PKM pyruvate kinase, muscle -0.037656
S100A6 S100 calcium binding protein A6 -0.0373201
RPS23 ribosomal protein S23 -0.0363069
PFN1 profilin 1 -0.0362851
RPS19 ribosomal protein S19 -0.0362682
RPL37A ribosomal protein L37a -0.0361574
PABPC1 poly(A) binding protein, cytoplasmic 1 -0.0349181
RBMS3 RNA binding motif, single stranded interacting protein 3 -0.0348509
ACTG1 actin gamma 1 -0.0347667
RPL34 ribosomal protein L34 -0.0345567
RPL9 ribosomal protein L9 -0.0339966
RPLP0 ribosomal protein, large, P0 -0.033522
RPS12 ribosomal protein S12 -0.0327987
RPL19 ribosomal protein L19 -0.0324786
RPL12 ribosomal protein L12 -0.0314674
RPL11 ribosomal protein L11 -0.0312174
B2M beta-2-microglobulin -0.0312058
RPLP2 ribosomal protein, large, P2 -0.0307887
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1 -0.0307689
NUCKS1 nuclear casein kinase and cyclin-dependent kinase substrate 1 -0.0302515
RPS13 ribosomal protein S13 -0.0284497
RPL26 ribosomal protein L26 -0.0276726
ARL4C ADP-ribosylation factor-like 4C -0.0274716
RPL36 ribosomal protein L36 -0.0273986
S100A9 S100 calcium binding protein A9 -0.0273096
RPS3 ribosomal protein S3 -0.0273
TMSB10 thymosin beta 10 -0.0259818
TOP2A topoisomerase (DNA) II alpha 170kDa -0.0256732
EIF1 eukaryotic translation initiation factor 1 -0.0255252
MT2A metallothionein 2A -0.0252507
RPL23 ribosomal protein L23 -0.0252184
POTEF POTE ankyrin domain family, member F -0.0251047
RPL32 ribosomal protein L32 -0.0247743
FTL ferritin, light polypeptide -0.0242749
HSPB1 heat shock 27kDa protein 1 -0.0239176
RPL7A ribosomal protein L7a -0.0235442
ENO2 enolase 2 (gamma, neuronal) -0.0233404
ENO1 enolase 1, (alpha) -0.0231493
CENPF centromere protein F, 350/400kDa -0.0230491
RPL8 ribosomal protein L8 -0.0226548
RPS25 ribosomal protein S25 -0.0220961
PRDX2 peroxiredoxin 2 -0.0210973
RACK1 receptor for activated C kinase 1 -0.020744
S100A10 S100 calcium binding protein A10 -0.0205097
MKI67 marker of proliferation Ki-67 -0.0202456
LDHA lactate dehydrogenase A -0.0202144
RPS27A ribosomal protein S27a -0.0200692
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 -0.0199406
NBEA neurobeachin -0.0195911
CCND1 cyclin D1 -0.0194815
RPL27A ribosomal protein L27a -0.0190713
HSPD1 heat shock 60kDa protein 1 (chaperonin) -0.0186266
RPS16 ribosomal protein S16 -0.0186104
RPS17 ribosomal protein S17 -0.0185136
RPS11 ribosomal protein S11 -0.0185054
RPS14 ribosomal protein S14 -0.0183938
RPS21 ribosomal protein S21 -0.0182643
SMC4 structural maintenance of chromosomes 4 -0.0174818
RPL28 ribosomal protein L28 -0.017445
RPS29 ribosomal protein S29 -0.0171394
RPL5 ribosomal protein L5 -0.0170939
RPS5 ribosomal protein S5 -0.016892
TPI1 triosephosphate isomerase 1 -0.0167808
RPS27 ribosomal protein S27 -0.0167044
SERPINB1 serpin peptidase inhibitor, clade B (ovalbumin), member 1 -0.0166479
RPL13A ribosomal protein L13a -0.0166188
TXNRD1 thioredoxin reductase 1 -0.0165692
NAV2 neuron navigator 2 -0.0163745
RPS4X ribosomal protein S4, X-linked -0.0163247
FOXP1 forkhead box P1 -0.0162744
RPS2 ribosomal protein S2 -0.0162632
SMC3 structural maintenance of chromosomes 3 -0.0160851
RPL27 ribosomal protein L27 -0.015848
RPL7 ribosomal protein L7 -0.0156249
RPS10 ribosomal protein S10 -0.0155634
TUBB4B tubulin, beta 4B class IVb -0.0153678
RPS15 ribosomal protein S15 -0.0153549
CENPE centromere protein E, 312kDa -0.0148637
NACA nascent polypeptide-associated complex alpha subunit -0.0146103
RPL18 ribosomal protein L18 -0.0145654
RPS24 ribosomal protein S24 -0.0144578
RPL17-C18ORF32 RPL17-C18orf32 readthrough -0.0143922
RPL36A ribosomal protein L36a -0.0143784
S100A4 S100 calcium binding protein A4 -0.0139296
CCNI cyclin I -0.0139096
RPL37 ribosomal protein L37 -0.0138601
MYL12B myosin, light chain 12B, regulatory -0.0136491
TM4SF1 transmembrane 4 L six family member 1 -0.0134806
NQO1 NAD(P)H dehydrogenase, quinone 1 -0.0134588
GCLM glutamate-cysteine ligase, modifier subunit -0.0134489
TPX2 TPX2, microtubule-associated -0.0134016
ARL6IP1 ADP-ribosylation factor-like 6 interacting protein 1 -0.0133984