Clozapine Gene Set

Dataset dbGAP Gene-Trait Associations
Category disease or phenotype associations
Type trait
Description A benzodiazepine that is 5H-dibenzo[b,e][1,4]diazepine substituted by a chloro group at position 8 and a 4-methylpiperazin-1-yl group at position 11. It is a second generation antipsychotic used in the treatment of psychiatric disorders like schizophrenia. (Chemical Entities of Biological Interest Ontology, CHEBI_3766)
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Genes

4 genes associated with the trait Clozapine in GWAS and other genetic association datasets from the dbGAP Gene-Trait Associations dataset.

Symbol Name Standardized Value
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta 0.67572
PPARD peroxisome proliferator-activated receptor delta 0.552134
CDH13 cadherin 13 0.50084
KIRREL3 kin of IRRE like 3 (Drosophila) 0.406869