Clubfoot Gene Set

Dataset DISEASES Text-mining Gene-Disease Association Evidence Scores 2025
Category disease or phenotype associations
Type disease
Description OMIM mapping confirmed by DO. [SN]. (Human Disease Ontology, DOID_11836)
Similar Terms
Downloads & Tools

Genes

281 genes co-occuring with the disease Clubfoot in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores 2025 dataset.

Symbol Name Standardized Value
CHST14 carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 14 2.941
PITX1 paired-like homeodomain 1 2.921
TBX4 T-box 4 2.851
SLC26A2 solute carrier family 26 (anion exchanger), member 2 2.621
MYH3 myosin, heavy chain 3, skeletal muscle, embryonic 2.594
TPM2 tropomyosin 2 (beta) 2.459
ZNF664 zinc finger protein 664 2.418
COL9A1 collagen, type IX, alpha 1 2.402
TNNI2 troponin I type 2 (skeletal, fast) 2.361
TNNT3 troponin T type 3 (skeletal, fast) 2.355
MYH8 myosin, heavy chain 8, skeletal muscle, perinatal 2.26
ECEL1 endothelin converting enzyme-like 1 2.246
MYBPC1 myosin binding protein C, slow type 2.238
COG4 component of oligomeric golgi complex 4 2.234
CHST3 carbohydrate (chondroitin 6) sulfotransferase 3 2.225
FLNB filamin B, beta 2.223
ZC4H2 zinc finger, C4H2 domain containing 2.175
COL9A3 collagen, type IX, alpha 3 2.091
HOXD12 homeobox D12 2.068
DSE dermatan sulfate epimerase 2.067
COL9A2 collagen, type IX, alpha 2 2.049
TNNC2 troponin C type 2 (fast) 2.015
HOXD13 homeobox D13 2.002
COL3A1 collagen, type III, alpha 1 1.992
HOXC13 homeobox C13 1.968
HOXD10 homeobox D10 1.958
HOXC12 homeobox C12 1.941
HOXC11 homeobox C11 1.932
PIEZO2 piezo-type mechanosensitive ion channel component 2 1.906
RBM10 RNA binding motif protein 10 1.862
SULT1C3 sulfotransferase family, cytosolic, 1C, member 3 1.859
SULT1C4 sulfotransferase family, cytosolic, 1C, member 4 1.843
FBN2 fibrillin 2 1.841
SULT1B1 sulfotransferase family, cytosolic, 1B, member 1 1.827
CAND2 cullin-associated and neddylation-dissociated 2 (putative) 1.813
CHRNG cholinergic receptor, nicotinic, gamma (muscle) 1.813
COL2A1 collagen, type II, alpha 1 1.806
MYBPC2 myosin binding protein C, fast type 1.805
TPM1 tropomyosin 1 (alpha) 1.79
SORCS1 sortilin-related VPS10 domain containing receptor 1 1.786
CHST8 carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8 1.783
TGDS TDP-glucose 4,6-dehydratase 1.764
GLI3 GLI family zinc finger 3 1.718
GDAP1 ganglioside induced differentiation associated protein 1 1.717
MATN3 matrilin 3 1.709
SOX9 SRY (sex determining region Y)-box 9 1.708
KLHL40 kelch-like family member 40 1.699
FOXN3 forkhead box N3 1.688
B4GALT7 xylosylprotein beta 1,4-galactosyltransferase, polypeptide 7 1.662
GDF5 growth differentiation factor 5 1.654
FBN1 fibrillin 1 1.649
MYH14 myosin, heavy chain 14, non-muscle 1.635
COL1A1 collagen, type I, alpha 1 1.62
CHSY1 chondroitin sulfate synthase 1 1.611
GMPPB GDP-mannose pyrophosphorylase B 1.608
DCN decorin 1.589
SCN4A sodium channel, voltage gated, type IV alpha subunit 1.581
PEX26 peroxisomal biogenesis factor 26 1.58
MTHFR methylenetetrahydrofolate reductase (NAD(P)H) 1.575
LMX1B LIM homeobox transcription factor 1, beta 1.573
SHOX short stature homeobox 1.538
CHRND cholinergic receptor, nicotinic, delta (muscle) 1.527
KIF1A kinesin family member 1A 1.523
PLOD1 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1 1.523
SMAD9 SMAD family member 9 1.521
ZBED5 zinc finger, BED-type containing 5 1.514
RYR1 ryanodine receptor 1 (skeletal) 1.512
CHD7 chromodomain helicase DNA binding protein 7 1.51
FKBP10 FK506 binding protein 10, 65 kDa 1.506
COL1A2 collagen, type I, alpha 2 1.498
CKM creatine kinase, muscle 1.497
TGFBR1 transforming growth factor, beta receptor 1 1.493
TBX1 T-box 1 1.493
CKMT2 creatine kinase, mitochondrial 2 (sarcomeric) 1.483
CKMT1B creatine kinase, mitochondrial 1B 1.482
BICD2 bicaudal D homolog 2 (Drosophila) 1.48
CKB creatine kinase, brain 1.479
TGFBR2 transforming growth factor, beta receptor II (70/80kDa) 1.47
DIS3L2 DIS3 like 3'-5' exoribonuclease 2 1.468
ACTA1 actin, alpha 1, skeletal muscle 1.468
CANT1 calcium activated nucleotidase 1 1.464
TCAP titin-cap 1.46
FLNA filamin A, alpha 1.46
SHH sonic hedgehog 1.452
NCOR2 nuclear receptor corepressor 2 1.442
MYH2 myosin, heavy chain 2, skeletal muscle, adult 1.435
MTM1 myotubularin 1 1.434
RAPSN receptor-associated protein of the synapse 1.429
HOXC10 homeobox C10 1.429
FSTL5 follistatin-like 5 1.426
COL5A2 collagen, type V, alpha 2 1.405
MED13L mediator complex subunit 13-like 1.404
PAPPA pregnancy-associated plasma protein A, pappalysin 1 1.403
KAT6B K(lysine) acetyltransferase 6B 1.402
SCARF2 scavenger receptor class F, member 2 1.401
SF3B4 splicing factor 3b, subunit 4, 49kDa 1.4
HOXC5 homeobox C5 1.389
MTMR2 myotubularin related protein 2 1.386
MAGEL2 melanoma antigen family L2 1.385
IRF6 interferon regulatory factor 6 1.384
SLC39A13 solute carrier family 39 (zinc transporter), member 13 1.381
FKBP14 FK506 binding protein 14, 22 kDa 1.374
SLC2A10 solute carrier family 2 (facilitated glucose transporter), member 10 1.373
FGD4 FYVE, RhoGEF and PH domain containing 4 1.373
TRPV4 transient receptor potential cation channel, subfamily V, member 4 1.371
TNNT1 troponin T type 1 (skeletal, slow) 1.365
TGFB3 transforming growth factor, beta 3 1.364
STAC3 SH3 and cysteine rich domain 3 1.357
GLRA1 glycine receptor, alpha 1 1.354
TGFB2 transforming growth factor, beta 2 1.354
CHRNA1 cholinergic receptor, nicotinic, alpha 1 (muscle) 1.352
SMAD3 SMAD family member 3 1.345
ACTA2 actin, alpha 2, smooth muscle, aorta 1.343
KLHL41 kelch-like family member 41 1.342
FAM50A family with sequence similarity 50, member A 1.339
B3GAT3 beta-1,3-glucuronyltransferase 3 1.338
PLOD2 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 1.336
AFP alpha-fetoprotein 1.334
ALG12 ALG12, alpha-1,6-mannosyltransferase 1.328
MSX1 msh homeobox 1 1.326
FHL1 four and a half LIM domains 1 1.326
CHST11 carbohydrate (chondroitin 4) sulfotransferase 11 1.322
RIPPLY2 ripply transcriptional repressor 2 1.315
KIF7 kinesin family member 7 1.31
TMEM262 transmembrane protein 262 1.31
POMT2 protein-O-mannosyltransferase 2 1.304
TBX5 T-box 5 1.296
GSC goosecoid homeobox 1.295
FRAS1 Fraser extracellular matrix complex subunit 1 1.293
TMEM216 transmembrane protein 216 1.292
FGFR3 fibroblast growth factor receptor 3 1.291
CHPF2 chondroitin polymerizing factor 2 1.291
MACROH2A1 macroH2A.1 histone 1.291
COL5A1 collagen, type V, alpha 1 1.29
KBTBD13 kelch repeat and BTB (POZ) domain containing 13 1.289
NEB nebulin 1.289
SNX24 sorting nexin 24 1.287
SELENON selenoprotein N 1.28
ASPN asporin 1.279
TGFB1 transforming growth factor, beta 1 1.279
TPM3 tropomyosin 3 1.279
MYH13 myosin, heavy chain 13, skeletal muscle 1.278
ZFYVE27 zinc finger, FYVE domain containing 27 1.277
TSSK3 testis-specific serine kinase 3 1.274
COL6A1 collagen, type VI, alpha 1 1.26
XYLT1 xylosyltransferase I 1.258
POMT1 protein-O-mannosyltransferase 1 1.257
ADAMTS6 ADAM metallopeptidase with thrombospondin type 1 motif, 6 1.256
B3GALT6 UDP-Gal:betaGal beta 1,3-galactosyltransferase polypeptide 6 1.253
TMEM67 transmembrane protein 67 1.248
HOXA9 homeobox A9 1.247
ACAN aggrecan 1.246
CPA6 carboxypeptidase A6 1.241
ZP2 zona pellucida glycoprotein 2 (sperm receptor) 1.241
COL6A2 collagen, type VI, alpha 2 1.238
TANC1 tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1 1.237
BGN biglycan 1.235
MNX1 motor neuron and pancreas homeobox 1 1.233
LMOD3 leiomodin 3 (fetal) 1.232
CSGALNACT1 chondroitin sulfate N-acetylgalactosaminyltransferase 1 1.231
EFEMP2 EGF containing fibulin-like extracellular matrix protein 2 1.227
FKRP fukutin related protein 1.224
LAMA2 laminin, alpha 2 1.224
DOK7 docking protein 7 1.222
MAF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog 1.221
SMN1 survival of motor neuron 1, telomeric 1.219
SEC24D SEC24 family member D 1.217
HOXC9 homeobox C9 1.213
SLC35D1 solute carrier family 35 (UDP-GlcA/UDP-GalNAc transporter), member D1 1.213
FKTN fukutin 1.211
ZIC2 Zic family member 2 1.205
YIPF7 Yip1 domain family, member 7 1.203
MKX mohawk homeobox 1.202
MKS1 Meckel syndrome, type 1 1.2
MYPN myopalladin 1.199
DAG1 dystroglycan 1 (dystrophin-associated glycoprotein 1) 1.196
CSGALNACT2 chondroitin sulfate N-acetylgalactosaminyltransferase 2 1.196
SALL1 spalt-like transcription factor 1 1.188
HNF1B HNF1 homeobox B 1.187
MYH1 myosin, heavy chain 1, skeletal muscle, adult 1.185
TANC2 tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 1.185
TMTC3 transmembrane and tetratricopeptide repeat containing 3 1.177
TCOF1 Treacher Collins-Franceschetti syndrome 1 1.171
TNXB tenascin XB 1.168
BHLHA9 basic helix-loop-helix family, member a9 1.167
MYH11 myosin, heavy chain 11, smooth muscle 1.161
ARFIP2 ADP-ribosylation factor interacting protein 2 1.161
HOXD9 homeobox D9 1.158
CHRNB1 cholinergic receptor, nicotinic, beta 1 (muscle) 1.156
HOXA13 homeobox A13 1.146
SMN2 survival of motor neuron 2, centromeric 1.14
FLNC filamin C, gamma 1.138
HS2ST1 heparan sulfate 2-O-sulfotransferase 1 1.138
PITX2 paired-like homeodomain 2 1.137
MED12 mediator complex subunit 12 1.136
DSEL dermatan sulfate epimerase-like 1.135
COL6A3 collagen, type VI, alpha 3 1.134
TM4SF20 transmembrane 4 L six family member 20 1.134
HOXD11 homeobox D11 1.134
CLCN1 chloride channel, voltage-sensitive 1 1.132
NALCN sodium leak channel, non selective 1.132
RXYLT1 ribitol xylosyltransferase 1 1.131
SYNE1 spectrin repeat containing, nuclear envelope 1 1.131
MUSTN1 musculoskeletal, embryonic nuclear protein 1 1.131
DGCR2 DiGeorge syndrome critical region gene 2 1.125
TTN titin 1.125
CHPF chondroitin polymerizing factor 1.122
TRIP11 thyroid hormone receptor interactor 11 1.121
MYBPC3 myosin binding protein C, cardiac 1.121
GLDN gliomedin 1.12
RBM8A RNA binding motif protein 8A 1.119
LMNA lamin A/C 1.118
ANKRD17 ankyrin repeat domain 17 1.114
PIK3C2A phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha 1.112
BRAT1 BRCA1-associated ATM activator 1 1.111
CRISPLD1 cysteine-rich secretory protein LCCL domain containing 1 1.111
ELN elastin 1.109
RPGRIP1L RPGRIP1-like 1.108
DYNC1H1 dynein, cytoplasmic 1, heavy chain 1 1.108
MYH7 myosin, heavy chain 7, cardiac muscle, beta 1.106
KPTN kaptin (actin binding protein) 1.105
MYH6 myosin, heavy chain 6, cardiac muscle, alpha 1.105
FAM50B family with sequence similarity 50, member B 1.104
MYLK myosin light chain kinase 1.103
SBF2 SET binding factor 2 1.103
XYLT2 xylosyltransferase II 1.101
CHST15 carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15 1.098
FAM20B family with sequence similarity 20, member B 1.096
ZSWIM6 zinc finger, SWIM-type containing 6 1.095
TBX2 T-box 2 1.093
SCAF4 SR-related CTD-associated factor 4 1.093
WNT7A wingless-type MMTV integration site family, member 7A 1.092
PRRX1 paired related homeobox 1 1.091
DISP1 dispatched homolog 1 (Drosophila) 1.091
POMGNT1 protein O-linked mannose N-acetylglucosaminyltransferase 1 (beta 1,2-) 1.08
ALG3 ALG3, alpha-1,3- mannosyltransferase 1.075
MYH4 myosin, heavy chain 4, skeletal muscle 1.074
VIPAS39 VPS33B interacting protein, apical-basolateral polarity regulator, spe-39 homolog 1.074
COMP cartilage oligomeric matrix protein 1.072
SNIP1 Smad nuclear interacting protein 1 1.067
HAPLN1 hyaluronan and proteoglycan link protein 1 1.065
TBX6 T-box 6 1.065
DBX2 developing brain homeobox 2 1.064
TMEM11 transmembrane protein 11 1.063
BBS9 Bardet-Biedl syndrome 9 1.062
PKHD1 polycystic kidney and hepatic disease 1 (autosomal recessive) 1.061
FREM2 FRAS1 related extracellular matrix protein 2 1.059
PRUNE1 prune exopolyphosphatase 1 1.057
ADGRG6 adhesion G protein-coupled receptor G6 1.054
TXNL4A thioredoxin-like 4A 1.054
MEGF10 multiple EGF-like-domains 10 1.054
LDB3 LIM domain binding 3 1.052
COG1 component of oligomeric golgi complex 1 1.049
DMD dystrophin 1.048
EPHA4 EPH receptor A4 1.048
FILIP1 filamin A interacting protein 1 1.047
SPECC1L sperm antigen with calponin homology and coiled-coil domains 1-like 1.046
MECOM MDS1 and EVI1 complex locus 1.046
TMEM38B transmembrane protein 38B 1.046
EYA1 EYA transcriptional coactivator and phosphatase 1 1.046
BRPF1 bromodomain and PHD finger containing, 1 1.043
LIMK1 LIM domain kinase 1 1.041
VPS33B vacuolar protein sorting 33 homolog B (yeast) 1.04
SH3TC2 SH3 domain and tetratricopeptide repeats 2 1.038
PAFAH1B1 platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) 1.037
FMOD fibromodulin 1.036
BMP4 bone morphogenetic protein 4 1.033
DOLK dolichol kinase 1.033
PUF60 poly-U binding splicing factor 60KDa 1.029
GMPPA GDP-mannose pyrophosphorylase A 1.027
DNM2 dynamin 2 1.022
SRY sex determining region Y 1.022
MYOD1 myogenic differentiation 1 1.021
VANGL1 VANGL planar cell polarity protein 1 1.02
NF1 neurofibromin 1 1.017
ADAMTS2 ADAM metallopeptidase with thrombospondin type 1 motif, 2 1.014
ARHGAP24 Rho GTPase activating protein 24 1.013
CHST5 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 5 1.005
C20ORF96 chromosome 20 open reading frame 96 1.005
SIX3 SIX homeobox 3 1.003
COL14A1 collagen, type XIV, alpha 1 1.001