Coccidioidomycosis Gene Set

Dataset DISEASES Text-mining Gene-Disease Association Evidence Scores 2025
Category disease or phenotype associations
Type disease
Description A primary systemic mycosis that results_in systemic fungal infection, has_material_basis_in Coccidioides immitis, transmitted_by airborne spores and has_symptom conjunctivitis, has_symptom arthritis, has_symptom chest pain and results_in_formation_of skin nodules. (Human Disease Ontology, DOID_13450)
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Genes

121 genes co-occuring with the disease Coccidioidomycosis in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores 2025 dataset.

Symbol Name Standardized Value
CLEC7A C-type lectin domain family 7, member A 2.6
CLEC6A C-type lectin domain family 6, member A 2.465
IFNG interferon, gamma 2.423
CD4 CD4 molecule 2.422
CARD9 caspase recruitment domain family, member 9 2.409
AMN1 antagonist of mitotic exit network 1 homolog (S. cerevisiae) 2.37
CYP51A1 cytochrome P450, family 51, subfamily A, polypeptide 1 2.297
IL12RB1 interleukin 12 receptor, beta 1 2.292
PEX19 peroxisomal biogenesis factor 19 2.271
PIGW phosphatidylinositol glycan anchor biosynthesis, class W 2.257
STAT1 signal transducer and activator of transcription 1, 91kDa 2.182
IL17A interleukin 17A 2.167
IFNGR1 interferon gamma receptor 1 2.085
TNF tumor necrosis factor 2.082
CHIT1 chitinase 1 (chitotriosidase) 2.072
CLEC4E C-type lectin domain family 4, member E 1.896
CD8A CD8a molecule 1.89
CRP C-reactive protein, pentraxin-related 1.852
IL10 interleukin 10 1.848
IL17RA interleukin 17 receptor A 1.795
CD101 CD101 molecule 1.778
IL4 interleukin 4 1.775
CLEC4D C-type lectin domain family 4, member D 1.765
CSF2 colony stimulating factor 2 (granulocyte-macrophage) 1.753
IL22 interleukin 22 1.744
IL6 interleukin 6 1.741
CHIA chitinase, acidic 1.702
DHODH dihydroorotate dehydrogenase (quinone) 1.697
IL2 interleukin 2 1.696
ALB albumin 1.684
TLR2 toll-like receptor 2 1.674
IL1B interleukin 1, beta 1.669
IL17F interleukin 17F 1.653
DOCK8 dedicator of cytokinesis 8 1.644
IFNGR2 interferon gamma receptor 2 (interferon gamma transducer 1) 1.644
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 1.634
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4 1.619
IL5 interleukin 5 1.592
MYD88 myeloid differentiation primary response 88 1.577
ZNF341 zinc finger protein 341 1.549
RABAC1 Rab acceptor 1 (prenylated) 1.533
CABP1 calcium binding protein 1 1.515
IL17RC interleukin 17 receptor C 1.514
IL1A interleukin 1, alpha 1.507
DUOXA1 dual oxidase maturation factor 1 1.495
NELFCD negative elongation factor complex member C/D 1.494
TYK2 tyrosine kinase 2 1.48
IL1R1 interleukin 1 receptor, type I 1.458
CYBB cytochrome b-245, beta polypeptide 1.458
RORC RAR-related orphan receptor C 1.456
CD209 CD209 molecule 1.429
CYP2C19 cytochrome P450, family 2, subfamily C, polypeptide 19 1.423
IFNA1 interferon, alpha 1 1.42
AIRE autoimmune regulator 1.416
TLR4 toll-like receptor 4 1.4
SYK spleen tyrosine kinase 1.399
PPIG peptidylprolyl isomerase G (cyclophilin G) 1.39
ACE angiotensin I converting enzyme 1.39
GATA2 GATA binding protein 2 1.38
JAK1 Janus kinase 1 1.375
HTN3 histatin 3 1.371
IL13 interleukin 13 1.365
EMB embigin 1.364
NCF4 neutrophil cytosolic factor 4, 40kDa 1.358
CLEC1A C-type lectin domain family 1, member A 1.333
CD40LG CD40 ligand 1.329
CSF3 colony stimulating factor 3 (granulocyte) 1.329
MBL2 mannose-binding lectin (protein C) 2, soluble 1.307
MALT1 MALT1 paracaspase 1.297
PLB1 phospholipase B1 1.284
PRTN3 proteinase 3 1.28
IL23A interleukin 23, alpha subunit p19 1.271
GPT glutamic-pyruvate transaminase (alanine aminotransferase) 1.264
MPO myeloperoxidase 1.26
ADA adenosine deaminase 1.258
CD40 CD40 molecule, TNF receptor superfamily member 5 1.256
BCL10 B-cell CLL/lymphoma 10 1.253
KCNB1 potassium channel, voltage gated Shab related subfamily B, member 1 1.237
GBA2 glucosidase, beta (bile acid) 2 1.224
RAG2 recombination activating gene 2 1.215
TRAF3IP2 TRAF3 interacting protein 2 1.208
NCF2 neutrophil cytosolic factor 2 1.206
GPR85 G protein-coupled receptor 85 1.196
PTX3 pentraxin 3, long 1.195
CTPS1 CTP synthase 1 1.195
CFP complement factor properdin 1.185
ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit) 1.18
ICAM3 intercellular adhesion molecule 3 1.173
HSPD1 heat shock 60kDa protein 1 (chaperonin) 1.172
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9 1.171
IRF8 interferon regulatory factor 8 1.16
CYBA cytochrome b-245, alpha polypeptide 1.158
JAK2 Janus kinase 2 1.157
CANX calnexin 1.155
CXCL8 chemokine (C-X-C motif) ligand 8 1.146
NCF1 neutrophil cytosolic factor 1 1.141
PLCG2 phospholipase C, gamma 2 (phosphatidylinositol-specific) 1.124
JAK3 Janus kinase 3 1.122
STAT4 signal transducer and activator of transcription 4 1.12
TLR9 toll-like receptor 9 1.12
ATP12A ATPase, H+/K+ transporting, nongastric, alpha polypeptide 1.112
BTK Bruton agammaglobulinemia tyrosine kinase 1.112
ATP4A ATPase, H+/K+ exchanging, alpha polypeptide 1.111
PGM3 phosphoglucomutase 3 1.111
FIBCD1 fibrinogen C domain containing 1 1.109
ITGAX integrin, alpha X (complement component 3 receptor 4 subunit) 1.103
TNFRSF10A tumor necrosis factor receptor superfamily, member 10a 1.101
POMC proopiomelanocortin 1.096
PTH parathyroid hormone 1.09
TGFB1 transforming growth factor, beta 1 1.084
CD80 CD80 molecule 1.084
DMAP1 DNA methyltransferase 1 associated protein 1 1.054
POLR2B polymerase (RNA) II (DNA directed) polypeptide B, 140kDa 1.045
FOXP3 forkhead box P3 1.035
CD19 CD19 molecule 1.023
ZNF2 zinc finger protein 2 1.022
PTPRC protein tyrosine phosphatase, receptor type, C 1.02
PNRC1 proline-rich nuclear receptor coactivator 1 1.015
HPD 4-hydroxyphenylpyruvate dioxygenase 1.012
CCL2 chemokine (C-C motif) ligand 2 1.0
IFNB1 interferon, beta 1, fibroblast 1.0