Colitis, Ulcerative Gene Set

Dataset HuGE Navigator Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
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Genes

352 genes associated with the Colitis, Ulcerative phenotype by text-mining GWAS publications from the HuGE Navigator Gene-Phenotype Associations dataset.

Symbol Name
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4
ACE angiotensin I converting enzyme
ADAD1 adenosine deaminase domain containing 1 (testis-specific)
ADRA2A adrenoceptor alpha 2A
AGER advanced glycosylation end product-specific receptor
AGR2 anterior gradient 2
AOC1 amine oxidase, copper containing 1
APC adenomatous polyposis coli
APEX1 APEX nuclease (multifunctional DNA repair enzyme) 1
APOE apolipoprotein E
ARPC2 actin related protein 2/3 complex, subunit 2, 34kDa
ATG16L1 autophagy related 16-like 1 (S. cerevisiae)
BANK1 B-cell scaffold protein with ankyrin repeats 1
BPI bactericidal/permeability-increasing protein
BRAF B-Raf proto-oncogene, serine/threonine kinase
BSN bassoon presynaptic cytomatrix protein
BTNL2 butyrophilin-like 2
C10ORF67 chromosome 10 open reading frame 67
C11ORF30 chromosome 11 open reading frame 30
C5ORF56 chromosome 5 open reading frame 56
CADM2 cell adhesion molecule 2
CALCOCO2 calcium binding and coiled-coil domain 2
CARD8 caspase recruitment domain family, member 8
CARD9 caspase recruitment domain family, member 9
CAT catalase
CCL11 chemokine (C-C motif) ligand 11
CCL2 chemokine (C-C motif) ligand 2
CCL24 chemokine (C-C motif) ligand 24
CCL26 chemokine (C-C motif) ligand 26
CCL3 chemokine (C-C motif) ligand 3
CCL5 chemokine (C-C motif) ligand 5
CCND1 cyclin D1
CCNY cyclin Y
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene)
CCR6 chemokine (C-C motif) receptor 6
CD14 CD14 molecule
CD209 CD209 molecule
CD24 CD24 molecule
CD40 CD40 molecule, TNF receptor superfamily member 5
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CDH3 cadherin 3, type 1, P-cadherin (placental)
CDKAL1 CDK5 regulatory subunit associated protein 1-like 1
CEP72 centrosomal protein 72kDa
CHRNA3 cholinergic receptor, nicotinic, alpha 3 (neuronal)
CIITA class II, major histocompatibility complex, transactivator
CLDN1 claudin 1
CLDN2 claudin 2
CLDN4 claudin 4
CLEC10A C-type lectin domain family 10, member A
CLEC2D C-type lectin domain family 2, member D
CLEC4A C-type lectin domain family 4, member A
CLIC1 chloride intracellular channel 1
CLSTN2 calsyntenin 2
CNR1 cannabinoid receptor 1 (brain)
CREM cAMP responsive element modulator
CTLA4 cytotoxic T-lymphocyte-associated protein 4
CUL2 cullin 2
CXCL12 chemokine (C-X-C motif) ligand 12
CXCL8 chemokine (C-X-C motif) ligand 8
CXCL9 chemokine (C-X-C motif) ligand 9
CXCR1 chemokine (C-X-C motif) receptor 1
CXCR2 chemokine (C-X-C motif) receptor 2
CXCR4 chemokine (C-X-C motif) receptor 4
CYBA cytochrome b-245, alpha polypeptide
CYP2A6 cytochrome P450, family 2, subfamily A, polypeptide 6
CYP2D6 cytochrome P450, family 2, subfamily D, polypeptide 6
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4
CYP3A5 cytochrome P450, family 3, subfamily A, polypeptide 5
DAGLB diacylglycerol lipase, beta
DAP death-associated protein
DCC DCC netrin 1 receptor
DEFA5 defensin, alpha 5, Paneth cell-specific
DEFB1 defensin, beta 1
DLD dihydrolipoamide dehydrogenase
DLG5 discs, large homolog 5 (Drosophila)
DRD2 dopamine receptor D2
ECM1 extracellular matrix protein 1
EED embryonic ectoderm development
ELMO1 engulfment and cell motility 1
EPX eosinophil peroxidase
F13A1 coagulation factor XIII, A1 polypeptide
F2 coagulation factor II (thrombin)
F5 coagulation factor V (proaccelerin, labile factor)
FAF1 Fas (TNFRSF6) associated factor 1
FAM92B family with sequence similarity 92, member B
FAS Fas cell surface death receptor
FCGR2A Fc fragment of IgG, low affinity IIa, receptor (CD32)
FCGR3A Fc fragment of IgG, low affinity IIIa, receptor (CD16a)
FCGR3B Fc fragment of IgG, low affinity IIIb, receptor (CD16b)
FGFR1OP FGFR1 oncogene partner
FIS1 fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae)
FKBP5 FK506 binding protein 5
FOS FBJ murine osteosarcoma viral oncogene homolog
FUT2 fucosyltransferase 2 (secretor status included)
GALNT2 polypeptide N-acetylgalactosaminyltransferase 2
GAS7 growth arrest-specific 7
GCKR glucokinase (hexokinase 4) regulator
GGH gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase)
GLP2R glucagon-like peptide 2 receptor
GNA12 guanine nucleotide binding protein (G protein) alpha 12
GPBAR1 G protein-coupled bile acid receptor 1
GPC5 glypican 5
GPSM3 G-protein signaling modulator 3
GRM8 glutamate receptor, metabotropic 8
GSDMB gasdermin B
GSTM1 glutathione S-transferase mu 1
GSTP1 glutathione S-transferase pi 1
GSTT1 glutathione S-transferase theta 1
GTF2E2 general transcription factor IIE, polypeptide 2, beta 34kDa
HERC2 HECT and RLD domain containing E3 ubiquitin protein ligase 2
HLA-A major histocompatibility complex, class I, A
HLA-B major histocompatibility complex, class I, B
HLA-C major histocompatibility complex, class I, C
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
HLA-DRA major histocompatibility complex, class II, DR alpha
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
HLA-DRB4 major histocompatibility complex, class II, DR beta 4
HLA-G major histocompatibility complex, class I, G
HMOX1 heme oxygenase 1
HNF4A hepatocyte nuclear factor 4, alpha
HNF4G hepatocyte nuclear factor 4, gamma
HNMT histamine N-methyltransferase
HNRNPA1P70 heterogeneous nuclear ribonucleoprotein A1 pseudogene 70
HP haptoglobin
HPRT1 hypoxanthine phosphoribosyltransferase 1
HSPA1B heat shock 70kDa protein 1B
HSPA1L heat shock 70kDa protein 1-like
HSPA2 heat shock 70kDa protein 2
HTATIP2 HIV-1 Tat interactive protein 2, 30kDa
IBD2 inflammatory bowel disease 2
IBD5 inflammatory bowel disease 5
ICAM1 intercellular adhesion molecule 1
ICOSLG inducible T-cell co-stimulator ligand
IFITM1 interferon induced transmembrane protein 1
IFITM3 interferon induced transmembrane protein 3
IFNG interferon, gamma
IGSF6 immunoglobulin superfamily, member 6
IL10 interleukin 10
IL10RA interleukin 10 receptor, alpha
IL10RB interleukin 10 receptor, beta
IL11 interleukin 11
IL12B interleukin 12B
IL13 interleukin 13
IL17A interleukin 17A
IL17F interleukin 17F
IL17REL interleukin 17 receptor E-like
IL18 interleukin 18
IL18RAP interleukin 18 receptor accessory protein
IL19 interleukin 19
IL1A interleukin 1, alpha
IL1B interleukin 1, beta
IL1F10 interleukin 1 family, member 10 (theta)
IL1R1 interleukin 1 receptor, type I
IL1R2 interleukin 1 receptor, type II
IL1RL1 interleukin 1 receptor-like 1
IL1RN interleukin 1 receptor antagonist
IL2 interleukin 2
IL20 interleukin 20
IL21 interleukin 21
IL22 interleukin 22
IL23R interleukin 23 receptor
IL26 interleukin 26
IL27 interleukin 27
IL2RA interleukin 2 receptor, alpha
IL2RB interleukin 2 receptor, beta
IL33 interleukin 33
IL4 interleukin 4
IL5 interleukin 5
IL6 interleukin 6
IL6STP1 interleukin 6 signal transducer (gp130, oncostatin M receptor) pseudogene 1
IL7R interleukin 7 receptor
IRAK3 interleukin-1 receptor-associated kinase 3
IRF5 interferon regulatory factor 5
IRGM immunity-related GTPase family, M
ITGB6 integrin, beta 6
ITLN1 intelectin 1 (galactofuranose binding)
ITPA inosine triphosphatase (nucleoside triphosphate pyrophosphatase)
JAK2 Janus kinase 2
KIAA1109 KIAA1109
KIF21B kinesin family member 21B
KIR2DL2 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 2
KIR2DL3 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 3
KLRC4 killer cell lectin-like receptor subfamily C, member 4
KRAS Kirsten rat sarcoma viral oncogene homolog
LACC1 laccase (multicopper oxidoreductase) domain containing 1
LAMB1 laminin, beta 1
LCT lactase
LMAN1 lectin, mannose-binding, 1
LOC400867 uncharacterized LOC400867
LPL lipoprotein lipase
LRRK2 leucine-rich repeat kinase 2
LSP1 lymphocyte-specific protein 1
LTA lymphotoxin alpha
LYRM4 LYR motif containing 4
MAGI2 membrane associated guanylate kinase, WW and PDZ domain containing 2
MAP3K1 mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
MBL2 mannose-binding lectin (protein C) 2, soluble
MEFV Mediterranean fever
MEP1A meprin A, alpha (PABA peptide hydrolase)
MICB MHC class I polypeptide-related sequence B
MIF macrophage migration inhibitory factor (glycosylation-inhibiting factor)
MIR146A microRNA 146a
MIR196A2 microRNA 196a-2
MIR499A microRNA 499a
MLH1 mutL homolog 1
MMP1 matrix metallopeptidase 1
MMP10 matrix metallopeptidase 10
MMP12 matrix metallopeptidase 12
MMP13 matrix metallopeptidase 13
MMP14 matrix metallopeptidase 14 (membrane-inserted)
MMP2 matrix metallopeptidase 2
MMP3 matrix metallopeptidase 3
MMP7 matrix metallopeptidase 7
MMP8 matrix metallopeptidase 8
MMP9 matrix metallopeptidase 9
MORC4 MORC family CW-type zinc finger 4
MST1 macrophage stimulating 1
MST1R macrophage stimulating 1 receptor
MT-TS1 tRNA
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
MTMR3 myotubularin related protein 3
MTR 5-methyltetrahydrofolate-homocysteine methyltransferase
MTRR 5-methyltetrahydrofolate-homocysteine methyltransferase reductase
MUC19 mucin 19, oligomeric
MYD88 myeloid differentiation primary response 88
MYO9B myosin IXB
NAT1 N-acetyltransferase 1 (arylamine N-acetyltransferase)
NAT2 N-acetyltransferase 2 (arylamine N-acetyltransferase)
NCF4 neutrophil cytosolic factor 4, 40kDa
NELL1 NEL-like 1 (chicken)
NFE2L2 nuclear factor, erythroid 2-like 2
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NFKBIL1 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
NKX2-3 NK2 homeobox 3
NLRP3 NLR family, pyrin domain containing 3
NM neutrophil migration
NOD1 nucleotide-binding oligomerization domain containing 1
NOD2 nucleotide-binding oligomerization domain containing 2
NOS1 nitric oxide synthase 1 (neuronal)
NOS2 nitric oxide synthase 2, inducible
NOS3 nitric oxide synthase 3 (endothelial cell)
NOTCH4 notch 4
NOX3 NADPH oxidase 3
NPSR1 neuropeptide S receptor 1
NQO1 NAD(P)H dehydrogenase, quinone 1
NR1H2 nuclear receptor subfamily 1, group H, member 2
NR1H4 nuclear receptor subfamily 1, group H, member 4
NR1I2 nuclear receptor subfamily 1, group I, member 2
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
OCTN3 organic cation transporter 3
OLIG3 oligodendrocyte transcription factor 3
OR5V1 olfactory receptor, family 5, subfamily V, member 1
ORMDL3 ORMDL sphingolipid biosynthesis regulator 3
OTUD3 OTU deubiquitinase 3
PADI4 peptidyl arginine deiminase, type IV
PARD3 par-3 family cell polarity regulator
PBX2 pre-B-cell leukemia homeobox 2
PDCD1 programmed cell death 1
PER3 period circadian clock 3
PHOX2B paired-like homeobox 2b
PLA2G2E phospholipase A2, group IIE
PLA2G7 phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma)
POU2F1 POU class 2 homeobox 1
PPARG peroxisome proliferator-activated receptor gamma
PPP2R5E protein phosphatase 2, regulatory subunit B', epsilon isoform
PPP3R2 protein phosphatase 3, regulatory subunit B, beta
PRDM1 PR domain containing 1, with ZNF domain
PRRC2A proline-rich coiled-coil 2A
PSMG1 proteasome (prosome, macropain) assembly chaperone 1
PTGER4 prostaglandin E receptor 4 (subtype EP4)
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PTPN11 protein tyrosine phosphatase, non-receptor type 11
PTPN2 protein tyrosine phosphatase, non-receptor type 2
PTPN22 protein tyrosine phosphatase, non-receptor type 22 (lymphoid)
PTPN6 protein tyrosine phosphatase, non-receptor type 6
PTRF polymerase I and transcript release factor
PUS10 pseudouridylate synthase 10
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
RAVER2 ribonucleoprotein, PTB-binding 2
REEP6 receptor accessory protein 6
REL v-rel avian reticuloendotheliosis viral oncogene homolog
RFC1 replication factor C (activator 1) 1, 145kDa
RNASE3 ribonuclease, RNase A family, 3
RNF186 ring finger protein 186
RUNX1 runt-related transcription factor 1
RUNX3 runt-related transcription factor 3
S100Z S100 calcium binding protein Z
SBNO2 strawberry notch homolog 2 (Drosophila)
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SFTPD surfactant protein D
SLC11A1 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1
SLC15A1 solute carrier family 15 (oligopeptide transporter), member 1
SLC22A23 solute carrier family 22, member 23
SLC22A4 solute carrier family 22 (organic cation/zwitterion transporter), member 4
SLC22A5 solute carrier family 22 (organic cation/carnitine transporter), member 5
SLC23A1 solute carrier family 23 (ascorbic acid transporter), member 1
SLC25A38P1 solute carrier family 25, member 38 pseudogene 1
SLC26A3 solute carrier family 26 (anion exchanger), member 3
SMAD2 SMAD family member 2
SOD2 superoxide dismutase 2, mitochondrial
SPP1 secreted phosphoprotein 1
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
STAT4 signal transducer and activator of transcription 4
STAT6 signal transducer and activator of transcription 6, interleukin-4 induced
STX8 syntaxin 8
TAB2 TGF-beta activated kinase 1/MAP3K7 binding protein 2
TCN2 transcobalamin II
TF transferrin
TGFB1 transforming growth factor, beta 1
TIMP1 TIMP metallopeptidase inhibitor 1
TIMP2 TIMP metallopeptidase inhibitor 2
TIMP3 TIMP metallopeptidase inhibitor 3
TIMP4 TIMP metallopeptidase inhibitor 4
TLE1 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
TLR1 toll-like receptor 1
TLR2 toll-like receptor 2
TLR4 toll-like receptor 4
TLR6 toll-like receptor 6
TLR9 toll-like receptor 9
TNF tumor necrosis factor
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TNFRSF14 tumor necrosis factor receptor superfamily, member 14
TNFRSF17 tumor necrosis factor receptor superfamily, member 17
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A
TNFRSF1B tumor necrosis factor receptor superfamily, member 1B
TNFRSF6B tumor necrosis factor receptor superfamily, member 6b, decoy
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TNFSF15 tumor necrosis factor (ligand) superfamily, member 15
TP53 tumor protein p53
TPMT thiopurine S-methyltransferase
TRAF3IP2 TRAF3 interacting protein 2
TRAF6 TNF receptor-associated factor 6, E3 ubiquitin protein ligase
TRIB1 tribbles pseudokinase 1
TRIM66 tripartite motif containing 66
UBE2L3 ubiquitin-conjugating enzyme E2L 3
UCP2 uncoupling protein 2 (mitochondrial, proton carrier)
UGT1A7 UDP glucuronosyltransferase 1 family, polypeptide A7
ULK1 unc-51 like autophagy activating kinase 1
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor
VIM vimentin
VIMP VCP-interacting membrane selenoprotein
VTCN1 V-set domain containing T cell activation inhibitor 1
XBP1 X-box binding protein 1
XRCC1 X-ray repair complementing defective repair in Chinese hamster cells 1
ZAP70 zeta-chain (TCR) associated protein kinase 70kDa
ZMIZ1 zinc finger, MIZ-type containing 1
ZNF365 zinc finger protein 365
ZPBP zona pellucida binding protein
ZPBP2 zona pellucida binding protein 2