Coloboma Gene Set

Dataset DISEASES Text-mining Gene-Disease Association Evidence Scores 2025
Category disease or phenotype associations
Type disease
Description An eye disease characterized by missing pieces of tissue in structures that form the eye, such as the iris, retina, choroid or optic disc. (Human Disease Ontology, DOID_12270)
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Genes

758 genes co-occuring with the disease Coloboma in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores 2025 dataset.

Symbol Name Standardized Value
CHD7 chromodomain helicase DNA binding protein 7 3.517
PAX2 paired box 2 3.125
PAX6 paired box 6 3.08
VAX2 ventral anterior homeobox 2 2.917
VSX2 visual system homeobox 2 2.899
OTX2 orthodenticle homeobox 2 2.842
TMEM67 transmembrane protein 67 2.795
VAX1 ventral anterior homeobox 1 2.78
FOXE3 forkhead box E3 2.738
MAB21L2 mab-21-like 2 (C. elegans) 2.703
GDF6 growth differentiation factor 6 2.69
TCOF1 Treacher Collins-Franceschetti syndrome 1 2.642
CC2D2A coiled-coil and C2 domain containing 2A 2.597
PIGL phosphatidylinositol glycan anchor biosynthesis, class L 2.561
STRA6 stimulated by retinoic acid 6 2.56
RPGRIP1L RPGRIP1-like 2.544
CEP290 centrosomal protein 290kDa 2.536
SHH sonic hedgehog 2.514
AHI1 Abelson helper integration site 1 2.496
TMEM216 transmembrane protein 216 2.487
PITX2 paired-like homeodomain 2 2.47
SIX3 SIX homeobox 3 2.466
NPHP1 nephronophthisis 1 (juvenile) 2.443
SRD5A3 steroid 5 alpha-reductase 3 2.412
ALDH1A3 aldehyde dehydrogenase 1 family, member A3 2.344
OFD1 oral-facial-digital syndrome 1 2.342
CPLANE1 ciliogenesis and planar polarity effector complex subunit 1 2.335
PROKR2 prokineticin receptor 2 2.312
FOXC1 forkhead box C1 2.304
ABCB6 ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group) 2.301
SOX2 SRY (sex determining region Y)-box 2 2.286
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha) 2.261
ACTG1 actin gamma 1 2.25
PUF60 poly-U binding splicing factor 60KDa 2.249
BMP4 bone morphogenetic protein 4 2.236
SIX6 SIX homeobox 6 2.233
ARL13B ADP-ribosylation factor-like 13B 2.224
PORCN porcupine homolog (Drosophila) 2.221
SEMA3E sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E 2.208
GDF3 growth differentiation factor 3 2.207
MKS1 Meckel syndrome, type 1 2.189
ATOH7 atonal homolog 7 (Drosophila) 2.182
KIAA0586 KIAA0586 2.178
TMEM237 transmembrane protein 237 2.168
SNAP25 synaptosomal-associated protein, 25kDa 2.157
POLR1D polymerase (RNA) I polypeptide D, 16kDa 2.147
TENM3 teneurin transmembrane protein 3 2.143
SMOC1 SPARC related modular calcium binding 1 2.14
ANOS1 anosmin 1 2.138
TCTN2 tectonic family member 2 2.106
MAB21L1 mab-21-like 1 (C. elegans) 2.1
CRYAA crystallin, alpha A 2.091
EYA1 EYA transcriptional coactivator and phosphatase 1 2.085
KIF7 kinesin family member 7 2.082
TCTN3 tectonic family member 3 2.074
SOX10 SRY (sex determining region Y)-box 10 2.071
PRDM13 PR domain containing 13 2.071
CRYBA4 crystallin, beta A4 2.07
CDON cell adhesion associated, oncogene regulated 2.068
FGF8 fibroblast growth factor 8 (androgen-induced) 2.058
IQCB1 IQ motif containing B1 2.051
FRAS1 Fraser extracellular matrix complex subunit 1 2.05
SALL2 spalt-like transcription factor 2 2.047
FREM1 FRAS1 related extracellular matrix 1 2.042
RAX retina and anterior neural fold homeobox 2.041
TBX1 T-box 1 2.039
BMP7 bone morphogenetic protein 7 2.032
CRX cone-rod homeobox 2.021
ZIC2 Zic family member 2 2.019
MITF microphthalmia-associated transcription factor 2.019
PITX3 paired-like homeodomain 3 2.018
HS6ST1 heparan sulfate 6-O-sulfotransferase 1 2.016
CDH7 cadherin 7, type 2 2.015
FZD5 frizzled class receptor 5 2.011
HESX1 HESX homeobox 1 2.001
FREM2 FRAS1 related extracellular matrix protein 2 1.998
SALL1 spalt-like transcription factor 1 1.995
TCTN1 tectonic family member 1 1.992
CDH20 cadherin 20, type 2 1.99
TMEM231 transmembrane protein 231 1.981
CLDN19 claudin 19 1.978
TBX5 T-box 5 1.978
GJA8 gap junction protein, alpha 8, 50kDa 1.973
B9D2 B9 protein domain 2 1.969
CRYBB2 crystallin, beta B2 1.961
PACS1 phosphofurin acidic cluster sorting protein 1 1.956
MAF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog 1.956
PIGV phosphatidylinositol glycan anchor biosynthesis, class V 1.953
TMEM138 transmembrane protein 138 1.952
KMT2D lysine (K)-specific methyltransferase 2D 1.949
CHD8 chromodomain helicase DNA binding protein 8 1.948
CRYGD crystallin, gamma D 1.947
ZNF503 zinc finger protein 503 1.947
RDH12 retinol dehydrogenase 12 (all-trans/9-cis/11-cis) 1.947
FGFR1 fibroblast growth factor receptor 1 1.942
EFTUD2 elongation factor Tu GTP binding domain containing 2 1.938
PROK2 prokineticin 2 1.935
NPHP4 nephronophthisis 4 1.933
CRYBB1 crystallin, beta B1 1.927
CDH19 cadherin 19, type 2 1.92
SOX11 SRY (sex determining region Y)-box 11 1.913
PTCH1 patched 1 1.907
TBC1D32 TBC1 domain family, member 32 1.907
PTCH2 patched 2 1.904
TTC21B tetratricopeptide repeat domain 21B 1.902
B9D1 B9 protein domain 1 1.899
WDR37 WD repeat domain 37 1.895
DHX38 DEAH (Asp-Glu-Ala-His) box polypeptide 38 1.889
RARB retinoic acid receptor, beta 1.887
LHX2 LIM homeobox 2 1.886
AIPL1 aryl hydrocarbon receptor interacting protein-like 1 1.883
VSX1 visual system homeobox 1 1.877
LCA5 Leber congenital amaurosis 5 1.876
ESX1 ESX homeobox 1 1.876
NSMF NMDA receptor synaptonuclear signaling and neuronal migration factor 1.873
PGAP2 post-GPI attachment to proteins 2 1.87
RPGRIP1 retinitis pigmentosa GTPase regulator interacting protein 1 1.869
GNRH1 gonadotropin-releasing hormone 1 (luteinizing-releasing hormone) 1.867
GLI3 GLI family zinc finger 3 1.861
SCLT1 sodium channel and clathrin linker 1 1.85
CHD9 chromodomain helicase DNA binding protein 9 1.848
HCCS holocytochrome c synthase 1.844
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1 1.841
HMX1 H6 family homeobox 1 1.836
PAX3 paired box 3 1.828
PRSS56 protease, serine, 56 1.826
GUCY2D guanylate cyclase 2D, membrane (retina-specific) 1.826
PAX1 paired box 1 1.824
SMARCA4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 1.821
RPE65 retinal pigment epithelium-specific protein 65kDa 1.82
BFSP1 beaded filament structural protein 1, filensin 1.811
PDE6D phosphodiesterase 6D, cGMP-specific, rod, delta 1.809
NMNAT1 nicotinamide nucleotide adenylyltransferase 1 1.809
CEP41 centrosomal protein 41kDa 1.804
RHO rhodopsin 1.799
ALX3 ALX homeobox 3 1.798
MSX1 msh homeobox 1 1.791
ALX1 ALX homeobox 1 1.791
PIGO phosphatidylinositol glycan anchor biosynthesis, class O 1.79
C5ORF52 chromosome 5 open reading frame 52 1.789
SIX1 SIX homeobox 1 1.789
TACR3 tachykinin receptor 3 1.784
FOXN1 forkhead box N1 1.784
ARMC9 armadillo repeat containing 9 1.781
PRR12 proline rich 12 1.78
C12ORF57 chromosome 12 open reading frame 57 1.778
FOXG1 forkhead box G1 1.778
RPGR retinitis pigmentosa GTPase regulator 1.777
PQBP1 polyglutamine binding protein 1 1.776
DOLK dolichol kinase 1.775
RERE arginine-glutamic acid dipeptide (RE) repeats 1.769
GLI2 GLI family zinc finger 2 1.765
NHEJ1 nonhomologous end-joining factor 1 1.754
GNRHR gonadotropin-releasing hormone receptor 1.748
SMARCA2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 1.747
PTK6 protein tyrosine kinase 6 1.746
IFT172 intraflagellar transport 172 1.746
CSPP1 centrosome and spindle pole associated protein 1 1.746
BEST1 bestrophin 1 1.744
YAP1 Yes-associated protein 1 1.743
SDCCAG8 serologically defined colon cancer antigen 8 1.741
B3GLCT beta 3-glucosyltransferase 1.74
TRIM8 tripartite motif containing 8 1.735
NPHP3 nephronophthisis 3 (adolescent) 1.734
CECR2 cat eye syndrome chromosome region, candidate 2 1.732
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa 1.728
CRYBA1 crystallin, beta A1 1.728
SEMA3A sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A 1.722
GJA3 gap junction protein, alpha 3, 46kDa 1.714
INVS inversin 1.712
FZD4 frizzled class receptor 4 1.712
SOX3 SRY (sex determining region Y)-box 3 1.71
OTX1 orthodenticle homeobox 1 1.709
SMAD9 SMAD family member 9 1.701
KISS1R KISS1 receptor 1.693
NR2E3 nuclear receptor subfamily 2, group E, member 3 1.691
ELP4 elongator acetyltransferase complex subunit 4 1.69
FOXD3 forkhead box D3 1.688
SOX9 SRY (sex determining region Y)-box 9 1.679
POU4F2 POU class 4 homeobox 2 1.678
CRYBB3 crystallin, beta B3 1.676
TBX2 T-box 2 1.667
FBN1 fibrillin 1 1.663
ZNF408 zinc finger protein 408 1.662
POLR1B polymerase (RNA) I polypeptide B, 128kDa 1.654
CNGB3 cyclic nucleotide gated channel beta 3 1.653
IL17RD interleukin 17 receptor D 1.653
C2CD3 C2 calcium-dependent domain containing 3 1.652
TULP1 tubby like protein 1 1.651
WT1 Wilms tumor 1 1.648
DCDC1 doublecortin domain containing 1 1.648
TAC3 tachykinin 3 1.641
CLDN16 claudin 16 1.639
GPR143 G protein-coupled receptor 143 1.632
HYLS1 hydrolethalus syndrome 1 1.631
PAX9 paired box 9 1.625
POLR1C polymerase (RNA) I polypeptide C, 30kDa 1.624
FLRT3 fibronectin leucine rich transmembrane protein 3 1.622
IFT80 intraflagellar transport 80 1.621
PDE6H phosphodiesterase 6H, cGMP-specific, cone, gamma 1.621
NR2F2 nuclear receptor subfamily 2, group F, member 2 1.619
IMMP1L IMP1 inner mitochondrial membrane peptidase-like (S. cerevisiae) 1.618
ABCA4 ATP-binding cassette, sub-family A (ABC1), member 4 1.618
CHD6 chromodomain helicase DNA binding protein 6 1.612
CYP26A1 cytochrome P450, family 26, subfamily A, polypeptide 1 1.607
FGFR2 fibroblast growth factor receptor 2 1.607
KDM6A lysine (K)-specific demethylase 6A 1.606
NR2F1 nuclear receptor subfamily 2, group F, member 1 1.605
SIX5 SIX homeobox 5 1.605
ZIC1 Zic family member 1 1.604
PRPH2 peripherin 2 (retinal degeneration, slow) 1.6
NDP Norrie disease (pseudoglioma) 1.596
FGF3 fibroblast growth factor 3 1.596
CRYGS crystallin, gamma S 1.595
FGF17 fibroblast growth factor 17 1.595
OCRL oculocerebrorenal syndrome of Lowe 1.593
ACTB actin, beta 1.591
GLI1 GLI family zinc finger 1 1.589
LRAT lecithin retinol acyltransferase (phosphatidylcholine--retinol O-acyltransferase) 1.586
PIGM phosphatidylinositol glycan anchor biosynthesis, class M 1.584
MPDU1 mannose-P-dolichol utilization defect 1 1.581
CELSR2 cadherin, EGF LAG seven-pass G-type receptor 2 1.581
FGF10 fibroblast growth factor 10 1.578
CRIM1 cysteine rich transmembrane BMP regulator 1 (chordin-like) 1.577
PIGW phosphatidylinositol glycan anchor biosynthesis, class W 1.577
DNAJC24 DnaJ (Hsp40) homolog, subfamily C, member 24 1.572
PTPN11 protein tyrosine phosphatase, non-receptor type 11 1.569
SF3B4 splicing factor 3b, subunit 4, 49kDa 1.569
NRBP2 nuclear receptor binding protein 2 1.568
ZIC3 Zic family member 3 1.567
FGF9 fibroblast growth factor 9 1.566
EYA2 EYA transcriptional coactivator and phosphatase 2 1.566
CRYGC crystallin, gamma C 1.565
SMARCA5 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5 1.56
CEP120 centrosomal protein 120kDa 1.56
EMX2 empty spiracles homeobox 2 1.556
ISL1 ISL LIM homeobox 1 1.556
SMO smoothened, frizzled class receptor 1.551
BFSP2 beaded filament structural protein 2, phakinin 1.549
POTEF POTE ankyrin domain family, member F 1.549
CNTLN centlein, centrosomal protein 1.548
IFT88 intraflagellar transport 88 1.548
GBX2 gastrulation brain homeobox 2 1.546
BBS1 Bardet-Biedl syndrome 1 1.544
BAZ1A bromodomain adjacent to zinc finger domain, 1A 1.542
ARL3 ADP-ribosylation factor-like 3 1.538
DNAH8 dynein, axonemal, heavy chain 8 1.538
IFT140 intraflagellar transport 140 1.537
PRCD progressive rod-cone degeneration 1.537
FGF4 fibroblast growth factor 4 1.537
DPM3 dolichyl-phosphate mannosyltransferase polypeptide 3 1.536
PIBF1 progesterone immunomodulatory binding factor 1 1.533
PRPF31 pre-mRNA processing factor 31 1.532
NTN1 netrin 1 1.532
PHC3 polyhomeotic homolog 3 (Drosophila) 1.53
WDR19 WD repeat domain 19 1.529
DPM1 dolichyl-phosphate mannosyltransferase polypeptide 1, catalytic subunit 1.529
FOXF1 forkhead box F1 1.529
MSX2 msh homeobox 2 1.528
USH2A Usher syndrome 2A (autosomal recessive, mild) 1.528
LMX1B LIM homeobox transcription factor 1, beta 1.526
ADAMTS16 ADAM metallopeptidase with thrombospondin type 1 motif, 16 1.525
SRY sex determining region Y 1.525
WDR35 WD repeat domain 35 1.524
SALL4 spalt-like transcription factor 4 1.521
PIGT phosphatidylinositol glycan anchor biosynthesis, class T 1.516
PIGA phosphatidylinositol glycan anchor biosynthesis, class A 1.516
H3-5 H3.5 histone 1.502
H3C13 H3 clustered histone 13 1.502
H3-4 H3.4 histone, cluster member 1.501
SLC6A3 solute carrier family 6 (neurotransmitter transporter), member 3 1.499
FAM161A family with sequence similarity 161, member A 1.499
CHD4 chromodomain helicase DNA binding protein 4 1.496
H3C12 H3 clustered histone 12 1.495
H3-3B H3.3 histone B 1.493
CHD1 chromodomain helicase DNA binding protein 1 1.493
SLC38A8 solute carrier family 38, member 8 1.492
FGF5 fibroblast growth factor 5 1.49
TMEM107 transmembrane protein 107 1.489
ZNF462 zinc finger protein 462 1.487
SMCHD1 structural maintenance of chromosomes flexible hinge domain containing 1 1.486
WNT9B wingless-type MMTV integration site family, member 9B 1.485
BRPF1 bromodomain and PHD finger containing, 1 1.484
MAB21L3 mab-21-like 3 (C. elegans) 1.484
FBN2 fibrillin 2 1.478
TMEM98 transmembrane protein 98 1.478
KIAA0753 KIAA0753 1.474
BBS2 Bardet-Biedl syndrome 2 1.474
TGFB1 transforming growth factor, beta 1 1.473
JAG1 jagged 1 1.472
FGF20 fibroblast growth factor 20 1.47
RARG retinoic acid receptor, gamma 1.469
ZNF703 zinc finger protein 703 1.468
POMT1 protein-O-mannosyltransferase 1 1.468
TBX3 T-box 3 1.468
FGF16 fibroblast growth factor 16 1.465
FGF6 fibroblast growth factor 6 1.465
FGF18 fibroblast growth factor 18 1.464
PIGG phosphatidylinositol glycan anchor biosynthesis, class G 1.462
FGF22 fibroblast growth factor 22 1.46
PGAP3 post-GPI attachment to proteins 3 1.458
ALG3 ALG3, alpha-1,3- mannosyltransferase 1.458
SUFU suppressor of fused homolog (Drosophila) 1.451
SHOC2 soc-2 suppressor of clear homolog (C. elegans) 1.45
KISS1 KiSS-1 metastasis-suppressor 1.449
SPATA7 spermatogenesis associated 7 1.448
ALDH1A2 aldehyde dehydrogenase 1 family, member A2 1.446
FGF7 fibroblast growth factor 7 1.446
SCRIB scribbled planar cell polarity protein 1.446
PDE6C phosphodiesterase 6C, cGMP-specific, cone, alpha prime 1.446
TP53 tumor protein p53 1.445
CYP26C1 cytochrome P450, family 26, subfamily C, polypeptide 1 1.445
OLFM2 olfactomedin 2 1.443
TFAP2B transcription factor AP-2 beta (activating enhancer binding protein 2 beta) 1.442
CDH4 cadherin 4, type 1, R-cadherin (retinal) 1.441
BBS4 Bardet-Biedl syndrome 4 1.441
PGAP1 post-GPI attachment to proteins 1 1.44
MFRP membrane frizzled-related protein 1.436
TBX6 T-box 6 1.435
FOXI3 forkhead box I3 1.435
ZDBF2 zinc finger, DBF-type containing 2 1.432
PIGK phosphatidylinositol glycan anchor biosynthesis, class K 1.431
WNT2B wingless-type MMTV integration site family, member 2B 1.43
CNNM4 cyclin and CBS domain divalent metal cation transport mediator 4 1.429
KDM2B lysine (K)-specific demethylase 2B 1.427
FEZF1 FEZ family zinc finger 1 1.426
HOXB1 homeobox B1 1.426
SMARCA1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1 1.426
NKX2-5 NK2 homeobox 5 1.424
PIGB phosphatidylinositol glycan anchor biosynthesis, class B 1.423
FRMD7 FERM domain containing 7 1.423
ZEB2 zinc finger E-box binding homeobox 2 1.421
PCARE photoreceptor cilium actin regulator 1.42
PDE6B phosphodiesterase 6B, cGMP-specific, rod, beta 1.42
MPDZ multiple PDZ domain protein 1.419
MEIS2 Meis homeobox 2 1.419
CHRD chordin 1.418
CFC1 cripto, FRL-1, cryptic family 1 1.417
COL9A3 collagen, type IX, alpha 3 1.416
TEAD1 TEA domain family member 1 (SV40 transcriptional enhancer factor) 1.413
GATA4 GATA binding protein 4 1.41
POC1B POC1 centriolar protein B 1.407
CEP164 centrosomal protein 164kDa 1.407
CPAMD8 C3 and PZP-like, alpha-2-macroglobulin domain containing 8 1.405
CNGA3 cyclic nucleotide gated channel alpha 3 1.405
RD3 retinal degeneration 3 1.402
GNAT2 guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2 1.401
NEK8 NIMA-related kinase 8 1.4
RDH5 retinol dehydrogenase 5 (11-cis/9-cis) 1.399
RARS1 arginyl-tRNA synthetase 1 1.397
FLNA filamin A, alpha 1.397
TTC8 tetratricopeptide repeat domain 8 1.395
RBP4 retinol binding protein 4, plasma 1.394
POMT2 protein-O-mannosyltransferase 2 1.392
ATP6V1E1 ATPase, H+ transporting, lysosomal 31kDa, V1 subunit E1 1.39
WNT1 wingless-type MMTV integration site family, member 1 1.389
CREBBP CREB binding protein 1.389
USH1C Usher syndrome 1C (autosomal recessive, severe) 1.388
ANKEF1 ankyrin repeat and EF-hand domain containing 1 1.387
LTBP2 latent transforming growth factor beta binding protein 2 1.386
KIF3A kinesin family member 3A 1.384
HNF1B HNF1 homeobox B 1.384
SOX4 SRY (sex determining region Y)-box 4 1.382
FGFR3 fibroblast growth factor receptor 3 1.38
ALMS1 Alstrom syndrome protein 1 1.377
PDE6A phosphodiesterase 6A, cGMP-specific, rod, alpha 1.376
NIPBL Nipped-B homolog (Drosophila) 1.376
SPECC1L sperm antigen with calponin homology and coiled-coil domains 1-like 1.373
NODAL nodal growth differentiation factor 1.372
NEUROD1 neuronal differentiation 1 1.371
LHX4 LIM homeobox 4 1.371
PROP1 PROP paired-like homeobox 1 1.37
HS2ST1 heparan sulfate 2-O-sulfotransferase 1 1.368
LTBP3 latent transforming growth factor beta binding protein 3 1.367
DOLPP1 dolichyldiphosphatase 1 1.365
POU3F4 POU class 3 homeobox 4 1.365
CHD3 chromodomain helicase DNA binding protein 3 1.363
POMGNT1 protein O-linked mannose N-acetylglucosaminyltransferase 1 (beta 1,2-) 1.362
ADAMTS17 ADAM metallopeptidase with thrombospondin type 1 motif, 17 1.362
PEX26 peroxisomal biogenesis factor 26 1.354
GJB2 gap junction protein, beta 2, 26kDa 1.352
TUBB3 tubulin, beta 3 class III 1.351
EVC2 Ellis van Creveld syndrome 2 1.351
SOS1 son of sevenless homolog 1 (Drosophila) 1.349
ALX4 ALX homeobox 4 1.348
EFNB1 ephrin-B1 1.347
EP300 E1A binding protein p300 1.345
COL4A1 collagen, type IV, alpha 1 1.344
COL11A1 collagen, type XI, alpha 1 1.344
STXBP6 syntaxin binding protein 6 (amisyn) 1.343
DLX5 distal-less homeobox 5 1.343
POLR1A polymerase (RNA) I polypeptide A, 194kDa 1.342
PIGY phosphatidylinositol glycan anchor biosynthesis, class Y 1.34
LAMB1 laminin, beta 1 1.339
LRP5 low density lipoprotein receptor-related protein 5 1.337
SRCAP Snf2-related CREBBP activator protein 1.335
BBS10 Bardet-Biedl syndrome 10 1.334
CRYBA2 crystallin, beta A2 1.333
FSHB follicle stimulating hormone, beta polypeptide 1.332
NRL neural retina leucine zipper 1.332
LRP2 low density lipoprotein receptor-related protein 2 1.331
ZPR1 ZPR1 zinc finger 1.33
RARA retinoic acid receptor, alpha 1.328
COL9A2 collagen, type IX, alpha 2 1.327
BMPR1A bone morphogenetic protein receptor, type IA 1.326
CACNA1F calcium channel, voltage-dependent, L type, alpha 1F subunit 1.325
IHH indian hedgehog 1.322
ROBO2 roundabout, axon guidance receptor, homolog 2 (Drosophila) 1.321
TBX20 T-box 20 1.318
CNGB1 cyclic nucleotide gated channel beta 1 1.318
ROM1 retinal outer segment membrane protein 1 1.316
EYS eyes shut homolog (Drosophila) 1.316
SH3PXD2B SH3 and PX domains 2B 1.315
GAPDH glyceraldehyde-3-phosphate dehydrogenase 1.315
FAT1 FAT atypical cadherin 1 1.314
MECP2 methyl CpG binding protein 2 1.311
DPM2 dolichyl-phosphate mannosyltransferase polypeptide 2, regulatory subunit 1.307
EFNB2 ephrin-B2 1.307
OPN1LW opsin 1 (cone pigments), long-wave-sensitive 1.307
CERKL ceramide kinase-like 1.306
DMXL2 Dmx-like 2 1.306
WNT8B wingless-type MMTV integration site family, member 8B 1.305
NEK9 NIMA-related kinase 9 1.303
SLC26A4 solute carrier family 26 (anion exchanger), member 4 1.3
NEUROD4 neuronal differentiation 4 1.3
FOXD1 forkhead box D1 1.295
LHX1 LIM homeobox 1 1.292
LRP6 low density lipoprotein receptor-related protein 6 1.291
SIX2 SIX homeobox 2 1.29
TMEM17 transmembrane protein 17 1.29
COL2A1 collagen, type II, alpha 1 1.289
SMARCC1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 1.289
FKRP fukutin related protein 1.288
PKHD1 polycystic kidney and hepatic disease 1 (autosomal recessive) 1.285
TFEC transcription factor EC 1.285
ZNF423 zinc finger protein 423 1.284
COL4A5 collagen, type IV, alpha 5 1.284
PIGQ phosphatidylinositol glycan anchor biosynthesis, class Q 1.281
HOXA2 homeobox A2 1.281
HAND2 heart and neural crest derivatives expressed 2 1.28
TBL1X transducin (beta)-like 1X-linked 1.278
MYO7A myosin VIIA 1.276
DDX59 DEAD (Asp-Glu-Ala-Asp) box polypeptide 59 1.275
PACS2 phosphofurin acidic cluster sorting protein 2 1.274
COL4A4 collagen, type IV, alpha 4 1.269
GPR161 G protein-coupled receptor 161 1.266
PTF1A pancreas specific transcription factor, 1a 1.266
CAPN15 calpain 15 1.264
BBS12 Bardet-Biedl syndrome 12 1.264
PLXNA1 plexin A1 1.263
POMC proopiomelanocortin 1.259
AXIN2 axin 2 1.259
FOXI2 forkhead box I2 1.258
POU4F3 POU class 4 homeobox 3 1.258
LAMA1 laminin, alpha 1 1.257
DKK2 dickkopf WNT signaling pathway inhibitor 2 1.256
DHDDS dehydrodolichyl diphosphate synthase 1.255
IFT43 intraflagellar transport 43 1.252
MICAL3 microtubule associated monooxygenase, calponin and LIM domain containing 3 1.251
ALG1 ALG1, chitobiosyldiphosphodolichol beta-mannosyltransferase 1.251
NKX2-2 NK2 homeobox 2 1.251
NDST2 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 2 1.249
ARHGAP28 Rho GTPase activating protein 28 1.248
RAB28 RAB28, member RAS oncogene family 1.248
KIF26B kinesin family member 26B 1.248
FOXA2 forkhead box A2 1.244
DHODH dihydroorotate dehydrogenase (quinone) 1.242
RP1L1 retinitis pigmentosa 1-like 1 1.242
MYOC myocilin, trabecular meshwork inducible glucocorticoid response 1.24
ADAMTS10 ADAM metallopeptidase with thrombospondin type 1 motif, 10 1.239
GDF11 growth differentiation factor 11 1.238
SNAI2 snail family zinc finger 2 1.237
RYBP RING1 and YY1 binding protein 1.236
DYNC2H1 dynein, cytoplasmic 2, heavy chain 1 1.235
ARID1B AT rich interactive domain 1B (SWI1-like) 1.234
PGBD2 piggyBac transposable element derived 2 1.233
ALDH1A1 aldehyde dehydrogenase 1 family, member A1 1.233
NR0B1 nuclear receptor subfamily 0, group B, member 1 1.233
CDH23 cadherin-related 23 1.231
CDH2 cadherin 2, type 1, N-cadherin (neuronal) 1.228
FKTN fukutin 1.228
GAS1 growth arrest-specific 1 1.228
CRKL v-crk avian sarcoma virus CT10 oncogene homolog-like 1.227
COL4A3 collagen, type IV, alpha 3 (Goodpasture antigen) 1.223
MNX1 motor neuron and pancreas homeobox 1 1.222
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific) 1.22
HSF4 heat shock transcription factor 4 1.22
DLX6 distal-less homeobox 6 1.22
TMX3 thioredoxin-related transmembrane protein 3 1.22
RBP1 retinol binding protein 1, cellular 1.217
CRYAB crystallin, alpha B 1.215
CYP26B1 cytochrome P450, family 26, subfamily B, polypeptide 1 1.213
IFT122 intraflagellar transport 122 1.213
IGF1 insulin-like growth factor 1 (somatomedin C) 1.21
ASXL2 additional sex combs like transcriptional regulator 2 1.21
RLBP1 retinaldehyde binding protein 1 1.209
IMPDH1 IMP (inosine 5'-monophosphate) dehydrogenase 1 1.207
GFAP glial fibrillary acidic protein 1.204
CRYGA crystallin, gamma A 1.204
FOXC2 forkhead box C2 1.203
TBX22 T-box 22 1.203
FOXL2 forkhead box L2 1.202
DCT dopachrome tautomerase 1.201
TYR tyrosinase 1.199
TSPAN12 tetraspanin 12 1.199
BANF1 barrier to autointegration factor 1 1.197
HRAS Harvey rat sarcoma viral oncogene homolog 1.197
RDH10 retinol dehydrogenase 10 (all-trans) 1.196
LETM1 leucine zipper-EF-hand containing transmembrane protein 1 1.196
NAA10 N(alpha)-acetyltransferase 10, NatA catalytic subunit 1.194
BMP3 bone morphogenetic protein 3 1.194
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 1.193
INPP5E inositol polyphosphate-5-phosphatase, 72 kDa 1.192
RAX2 retina and anterior neural fold homeobox 2 1.191
VPS35L VPS35 endosomal protein sorting factor like 1.191
POU4F1 POU class 4 homeobox 1 1.19
ADAMTSL4 ADAMTS-like 4 1.189
PLXND1 plexin D1 1.189
SLC4A11 solute carrier family 4, sodium borate transporter, member 11 1.189
SLC24A5 solute carrier family 24 (sodium/potassium/calcium exchanger), member 5 1.188
PHACTR4 phosphatase and actin regulator 4 1.188
GLB1 galactosidase, beta 1 1.188
SEMA7A semaphorin 7A, GPI membrane anchor (John Milton Hagen blood group) 1.187
PIGC phosphatidylinositol glycan anchor biosynthesis, class C 1.186
RGR retinal G protein coupled receptor 1.185
EMX1 empty spiracles homeobox 1 1.185
CABP4 calcium binding protein 4 1.185
CCDC141 coiled-coil domain containing 141 1.185
WDR11 WD repeat domain 11 1.184
PIGH phosphatidylinositol glycan anchor biosynthesis, class H 1.183
ARR3 arrestin 3, retinal (X-arrestin) 1.18
ALB albumin 1.18
BBS9 Bardet-Biedl syndrome 9 1.179
FRS2 fibroblast growth factor receptor substrate 2 1.179
ALG6 ALG6, alpha-1,3-glucosyltransferase 1.179
CDH17 cadherin 17, LI cadherin (liver-intestine) 1.178
SMC1A structural maintenance of chromosomes 1A 1.177
TJP1 tight junction protein 1 1.175
NOG noggin 1.175
SLITRK5 SLIT and NTRK-like family, member 5 1.171
SPRY4 sprouty homolog 4 (Drosophila) 1.171
KERA keratocan 1.17
KCNV2 potassium channel, voltage gated modifier subfamily V, member 2 1.169
ALG12 ALG12, alpha-1,6-mannosyltransferase 1.169
CCNQ cyclin Q 1.168
COL11A2 collagen, type XI, alpha 2 1.167
DRD5 dopamine receptor D5 1.166
KIF21A kinesin family member 21A 1.165
SDR9C7 short chain dehydrogenase/reductase family 9C, member 7 1.165
DOCK8 dedicator of cytokinesis 8 1.164
FYCO1 FYVE and coiled-coil domain containing 1 1.163
NYX nyctalopin 1.162
KIFBP kinesin family binding protein 1.161
RFX4 regulatory factor X, 4 (influences HLA class II expression) 1.16
EXTL3 exostosin-like glycosyltransferase 3 1.16
MMP19 matrix metallopeptidase 19 1.159
MROH2A maestro heat-like repeat family member 2A 1.158
PAXIP1 PAX interacting (with transcription-activation domain) protein 1 1.158
EPYC epiphycan 1.155
OTUD4 OTU deubiquitinase 4 1.154
PMM2 phosphomannomutase 2 1.154
ALG2 ALG2, alpha-1,3/1,6-mannosyltransferase 1.153
TRPM3 transient receptor potential cation channel, subfamily M, member 3 1.149
RAB8A RAB8A, member RAS oncogene family 1.146
RCVRN recoverin 1.146
ZFPM1 zinc finger protein, FOG family member 1 1.145
RAB3GAP1 RAB3 GTPase activating protein subunit 1 (catalytic) 1.145
KAT6B K(lysine) acetyltransferase 6B 1.144
SOX1 SRY (sex determining region Y)-box 1 1.144
LHX3 LIM homeobox 3 1.142
TXNL4A thioredoxin-like 4A 1.142
BMPR1B bone morphogenetic protein receptor, type IB 1.141
DKK1 dickkopf WNT signaling pathway inhibitor 1 1.141
ADNP activity-dependent neuroprotector homeobox 1.139
LEF1 lymphoid enhancer-binding factor 1 1.139
PXDN peroxidasin 1.134
CHRDL1 chordin-like 1 1.133
GPAA1 glycosylphosphatidylinositol anchor attachment 1 1.13
SIX4 SIX homeobox 4 1.13
RDH8 retinol dehydrogenase 8 (all-trans) 1.129
IGSF10 immunoglobulin superfamily, member 10 1.128
SOX21 SRY (sex determining region Y)-box 21 1.128
IFT57 intraflagellar transport 57 1.128
TMEM114 transmembrane protein 114 1.128
LEFTY2 left-right determination factor 2 1.128
EGF epidermal growth factor 1.127
ARL6IP1 ADP-ribosylation factor-like 6 interacting protein 1 1.127
SMARCC2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2 1.127
TTLL5 tubulin tyrosine ligase-like family member 5 1.127
RELN reelin 1.126
RNF32 ring finger protein 32 1.124
GRHL3 grainyhead-like 3 (Drosophila) 1.124
HMGB3 high mobility group box 3 1.124
GLIS2 GLIS family zinc finger 2 1.122
MBTPS2 membrane-bound transcription factor peptidase, site 2 1.122
NEK1 NIMA-related kinase 1 1.121
DHCR7 7-dehydrocholesterol reductase 1.12
HOXA3 homeobox A3 1.12
TTLL10 tubulin tyrosine ligase-like family member 10 1.119
COL9A1 collagen, type IX, alpha 1 1.116
LNX1 ligand of numb-protein X 1, E3 ubiquitin protein ligase 1.116
SFRP2 secreted frizzled-related protein 2 1.115
FAM149B1 family with sequence similarity 149, member B1 1.112
P3H2 prolyl 3-hydroxylase 2 1.112
OPN4 opsin 4 1.111
WNT11 wingless-type MMTV integration site family, member 11 1.11
ALG11 ALG11, alpha-1,2-mannosyltransferase 1.11
H2BC21 H2B clustered histone 21 1.109
PKD2 polycystic kidney disease 2 (autosomal dominant) 1.108
RASA1 RAS p21 protein activator (GTPase activating protein) 1 1.108
ASCL1 achaete-scute family bHLH transcription factor 1 1.108
LLPH LLP homolog, long-term synaptic facilitation (Aplysia) 1.105
DRD4 dopamine receptor D4 1.103
NEUROG2 neurogenin 2 1.102
KIF3B kinesin family member 3B 1.102
ZNF718 zinc finger protein 718 1.102
MYRF myelin regulatory factor 1.102
POU5F1 POU class 5 homeobox 1 1.102
NF1 neurofibromin 1 1.101
WNT4 wingless-type MMTV integration site family, member 4 1.101
DLX2 distal-less homeobox 2 1.101
EFNA5 ephrin-A5 1.099
MYO10 myosin X 1.099
DISP1 dispatched homolog 1 (Drosophila) 1.098
ZFPM2 zinc finger protein, FOG family member 2 1.098
H2AZ2 H2A.Z variant histone 2 1.098
RBM8A RNA binding motif protein 8A 1.098
PRL prolactin 1.097
GDF1 growth differentiation factor 1 1.097
HNF4A hepatocyte nuclear factor 4, alpha 1.096
NRAS neuroblastoma RAS viral (v-ras) oncogene homolog 1.096
POMGNT2 protein O-linked mannose N-acetylglucosaminyltransferase 2 (beta 1,4-) 1.095
DAG1 dystroglycan 1 (dystrophin-associated glycoprotein 1) 1.095
ZNF672 zinc finger protein 672 1.095
WDPCP WD repeat containing planar cell polarity effector 1.094
H2AC20 H2A clustered histone 20 1.094
GDNF glial cell derived neurotrophic factor 1.093
H2AC18 H2A clustered histone 18 1.093
MTOR mechanistic target of rapamycin (serine/threonine kinase) 1.093
SOX8 SRY (sex determining region Y)-box 8 1.091
ZIC5 Zic family member 5 1.089
MAPK9 mitogen-activated protein kinase 9 1.087
CWC27 CWC27 spliceosome-associated protein homolog (S. cerevisiae) 1.087
NSD2 nuclear receptor binding SET domain protein 2 1.087
VPS13B vacuolar protein sorting 13 homolog B (yeast) 1.087
TWF1 twinfilin actin binding protein 1 1.086
PDGFRA platelet-derived growth factor receptor, alpha polypeptide 1.086
IRF6 interferon regulatory factor 6 1.086
TUBA1A tubulin, alpha 1a 1.086
CLDN10 claudin 10 1.086
SAXO2 stabilizer of axonemal microtubules 2 1.086
COQ8B coenzyme Q8B 1.085
MAMLD1 mastermind-like domain containing 1 1.084
RPS19 ribosomal protein S19 1.084
DICER1 dicer 1, ribonuclease type III 1.084
CNGA1 cyclic nucleotide gated channel alpha 1 1.083
TENM1 teneurin transmembrane protein 1 1.083
AFAP1L2 actin filament associated protein 1-like 2 1.083
DPY19L3 dpy-19-like 3 (C. elegans) 1.083
NOTCH1 notch 1 1.08
PAX8 paired box 8 1.08
FSCN2 fascin actin-bundling protein 2, retinal 1.079
BDP1 B double prime 1, subunit of RNA polymerase III transcription initiation factor IIIB 1.078
EHMT1 euchromatic histone-lysine N-methyltransferase 1 1.078
TP63 tumor protein p63 1.078
KRAS Kirsten rat sarcoma viral oncogene homolog 1.077
ATOH1 atonal homolog 1 (Drosophila) 1.077
TDRD7 tudor domain containing 7 1.077
OCA2 oculocutaneous albinism II 1.075
IMPG1 interphotoreceptor matrix proteoglycan 1 1.075
WDR5 WD repeat domain 5 1.073
ARL13A ADP-ribosylation factor-like 13A 1.072
KCNJ13 potassium channel, inwardly rectifying subfamily J, member 13 1.07
MPI mannose phosphate isomerase 1.07
BCOR BCL6 corepressor 1.069
BDNF brain-derived neurotrophic factor 1.069
PLCE1 phospholipase C, epsilon 1 1.069
GP1BB glycoprotein Ib (platelet), beta polypeptide 1.069
RAB3GAP2 RAB3 GTPase activating protein subunit 2 (non-catalytic) 1.069
TYRP1 tyrosinase-related protein 1 1.068
RAG1 recombination activating gene 1 1.068
LAMC1 laminin, gamma 1 (formerly LAMB2) 1.067
SLC16A12 solute carrier family 16, member 12 1.066
NDST1 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1 1.064
KIF11 kinesin family member 11 1.062
TUBA8 tubulin, alpha 8 1.061
POLR3B polymerase (RNA) III (DNA directed) polypeptide B 1.061
PROX1 prospero homeobox 1 1.061
RIMS1 regulating synaptic membrane exocytosis 1 1.06
PIGP phosphatidylinositol glycan anchor biosynthesis, class P 1.06
BBS5 Bardet-Biedl syndrome 5 1.058
SLIT3 slit homolog 3 (Drosophila) 1.058
COL8A2 collagen, type VIII, alpha 2 1.057
CHD2 chromodomain helicase DNA binding protein 2 1.057
ASH2L ash2 (absent, small, or homeotic)-like (Drosophila) 1.057
TULP3 tubby like protein 3 1.056
NXNL1 nucleoredoxin-like 1 1.054
FN1 fibronectin 1 1.054
ADAM9 ADAM metallopeptidase domain 9 1.053
MAB21L4 mab-21 like 4 1.053
DVL1 dishevelled segment polarity protein 1 1.051
EAPP E2F-associated phosphoprotein 1.051
CASP3 caspase 3, apoptosis-related cysteine peptidase 1.05
LGALS4 lectin, galactoside-binding, soluble, 4 1.05
CCDC13 coiled-coil domain containing 13 1.05
PAX7 paired box 7 1.049
CHST14 carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 14 1.049
RDH11 retinol dehydrogenase 11 (all-trans/9-cis/11-cis) 1.047
PCDH15 protocadherin-related 15 1.046
ZNF595 zinc finger protein 595 1.044
SETD1A SET domain containing 1A 1.044
BAZ1B bromodomain adjacent to zinc finger domain, 1B 1.042
MYC v-myc avian myelocytomatosis viral oncogene homolog 1.04
BBS7 Bardet-Biedl syndrome 7 1.035
CCDC22 coiled-coil domain containing 22 1.033
FEZ2 fasciculation and elongation protein zeta 2 (zygin II) 1.033
NPHS1 nephrosis 1, congenital, Finnish type (nephrin) 1.032
NSD1 nuclear receptor binding SET domain protein 1 1.029
SNAP29 synaptosomal-associated protein, 29kDa 1.029
PAX4 paired box 4 1.028
NEPRO nucleolus and neural progenitor protein 1.028
TGFB2 transforming growth factor, beta 2 1.027
SLC25A18 solute carrier family 25 (glutamate carrier), member 18 1.027
ALG8 ALG8, alpha-1,3-glucosyltransferase 1.027
SMARCD3 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3 1.026
WNT7B wingless-type MMTV integration site family, member 7B 1.024
MAPK8 mitogen-activated protein kinase 8 1.023
MYCN v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog 1.022
MESP2 mesoderm posterior basic helix-loop-helix transcription factor 2 1.022
WNT3A wingless-type MMTV integration site family, member 3A 1.02
TIMM8A translocase of inner mitochondrial membrane 8 homolog A (yeast) 1.019
SHISA2 shisa family member 2 1.019
SMARCE1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1 1.017
LHX8 LIM homeobox 8 1.016
CDX1 caudal type homeobox 1 1.016
CPLX1 complexin 1 1.014
CEP83 centrosomal protein 83kDa 1.014
MYH14 myosin, heavy chain 14, non-muscle 1.013
PHGDH phosphoglycerate dehydrogenase 1.013
CCER1 coiled-coil glutamate-rich protein 1 1.011
SLF2 SMC5-SMC6 complex localization factor 2 1.01
ISOC2 isochorismatase domain containing 2 1.01
UMOD uromodulin 1.01
TGIF1 TGFB-induced factor homeobox 1 1.009
RNF216 ring finger protein 216 1.009
PKD1 polycystic kidney disease 1 (autosomal dominant) 1.008
BMP2 bone morphogenetic protein 2 1.008
ACTC1 actin, alpha, cardiac muscle 1 1.004
TP53TG3B TP53 target 3B 1.004
B3GAT3 beta-1,3-glucuronyltransferase 3 1.003
IFT54 intraflagellar transport 54 1.003
FLVCR1 feline leukemia virus subgroup C cellular receptor 1 1.003
MMACHC methylmalonic aciduria (cobalamin deficiency) cblC type, with homocystinuria 1.002
COX7B cytochrome c oxidase subunit VIIb 1.002
CDHR1 cadherin-related family member 1 1.002
INS insulin 1.001
AKT1 v-akt murine thymoma viral oncogene homolog 1 1.0
DHH desert hedgehog 1.0