Complement activation Gene Set
Dataset
WikiPathways Pathways 2024
Category
structural or functional annotations
Type
pathway
Description
Any process involved in the activation of any of the steps of the complement cascade, which allows for the direct killing of microbes, the disposal of immune complexes, and the regulation of other immune processes; the initial steps of complement activation involve one of three pathways, the classical pathway, the alternative pathway, and the lectin pathway, all of which lead to the terminal complement pathway. (Gene Ontology , GO_0006956 )
External Link
https://www.wikipathways.org/pathways/WP545.html
Similar Terms
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Genes
23 proteins participating in the Complement activation pathway from the WikiPathways Pathways 2024 dataset.
Symbol
Name
C1QA
complement component 1, q subcomponent, A chain
C1QB
complement component 1, q subcomponent, B chain
C1QC
complement component 1, q subcomponent, C chain
C1R
complement component 1, r subcomponent
C1S
complement component 1, s subcomponent
C2
complement component 2
C3
complement component 3
C4A
complement component 4A (Rodgers blood group)
C4B
complement component 4B (Chido blood group)
C5
complement component 5
C6
complement component 6
C7
complement component 7
C8A
complement component 8, alpha polypeptide
C8B
complement component 8, beta polypeptide
C8G
complement component 8, gamma polypeptide
C9
complement component 9
CD55
CD55 molecule, decay accelerating factor for complement (Cromer blood group)
CFB
complement factor B
CFD
complement factor D (adipsin)
CFP
complement factor properdin
LOC107987478
cytochrome P450 2D6-like
MASP1
mannan-binding lectin serine peptidase 1 (C4/C2 activating component of Ra-reactive factor)
MASP2
mannan-binding lectin serine peptidase 2
