Complement cascade Gene Set

Dataset Reactome Pathways 2024
Category structural or functional annotations
Type pathway
External Link https://reactome.org/PathwayBrowser/#/R-HSA-166658
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Genes

61 proteins participating in the Complement cascade pathway from the Reactome Pathways 2024 dataset.

Symbol Name
C1QA complement component 1, q subcomponent, A chain
C1QB complement component 1, q subcomponent, B chain
C1QC complement component 1, q subcomponent, C chain
C1R complement component 1, r subcomponent
C1S complement component 1, s subcomponent
C2 complement component 2
C3 complement component 3
C3AR1 complement component 3a receptor 1
C4A complement component 4A (Rodgers blood group)
C4B complement component 4B (Chido blood group)
C4BPA complement component 4 binding protein, alpha
C4BPB complement component 4 binding protein, beta
C5 complement component 5
C5AR1 complement component 5a receptor 1
C5AR2 complement component 5a receptor 2
C6 complement component 6
C7 complement component 7
C8A complement component 8, alpha polypeptide
C8B complement component 8, beta polypeptide
C8G complement component 8, gamma polypeptide
C9 complement component 9
CD19 CD19 molecule
CD46 CD46 molecule, complement regulatory protein
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group)
CD59 CD59 molecule, complement regulatory protein
CD81 CD81 molecule
CFB complement factor B
CFD complement factor D (adipsin)
CFH complement factor H
CFHR1 complement factor H-related 1
CFHR2 complement factor H-related 2
CFHR3 complement factor H-related 3
CFHR4 complement factor H-related 4
CFHR5 complement factor H-related 5
CFI complement factor I
CFP complement factor properdin
CLU clusterin
COLEC10 collectin sub-family member 10 (C-type lectin)
COLEC11 collectin sub-family member 11
CPB2 carboxypeptidase B2 (plasma)
CPN1 carboxypeptidase N, polypeptide 1
CPN2 carboxypeptidase N, polypeptide 2
CR1 complement component (3b/4b) receptor 1 (Knops blood group)
CR2 complement component (3d/Epstein Barr virus) receptor 2
CRP C-reactive protein, pentraxin-related
ELANE elastase, neutrophil expressed
F2 coagulation factor II (thrombin)
FCN1 ficolin (collagen/fibrinogen domain containing) 1
FCN2 ficolin (collagen/fibrinogen domain containing lectin) 2
FCN3 ficolin (collagen/fibrinogen domain containing) 3
GZMM granzyme M (lymphocyte met-ase 1)
IGH immunoglobulin heavy locus
IGL immunoglobulin lambda locus
IGLL5 immunoglobulin lambda-like polypeptide 5
LOC102723407 putative V-set and immunoglobulin domain-containing-like protein IGHV4OR15-8
MASP1 mannan-binding lectin serine peptidase 1 (C4/C2 activating component of Ra-reactive factor)
MASP2 mannan-binding lectin serine peptidase 2
MBL2 mannose-binding lectin (protein C) 2, soluble
PROS1 protein S (alpha)
SERPING1 serpin peptidase inhibitor, clade G (C1 inhibitor), member 1
VTN vitronectin