Complicated Malaria Gene Set

Dataset DisGeNET Gene-Disease Associations
Category disease or phenotype associations
Type disease
External Link https://www.disgenet.org/browser/0/1/0/C2747816
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Genes

160 genes associated with the disease Complicated Malaria in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.

Symbol Name
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1
ABO ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase)
ACKR1 atypical chemokine receptor 1 (Duffy blood group)
ADCY9 adenylate cyclase 9
ADGRE1 adhesion G protein-coupled receptor E1
ADORA2A adenosine A2a receptor
ADORA2B adenosine A2b receptor
AIF1 allograft inflammatory factor 1
ALB albumin
AMPD1 adenosine monophosphate deaminase 1
ANGPT1 angiopoietin 1
ANGPT2 angiopoietin 2
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2
ATAD1 ATPase family, AAA domain containing 1
ATP2B4 ATPase, Ca++ transporting, plasma membrane 4
BCL6 B-cell CLL/lymphoma 6
BDNF brain-derived neurotrophic factor
BSG basigin (Ok blood group)
C1ORF228 chromosome 1 open reading frame 228
CA11 carbonic anhydrase XI
CCL3L1 chemokine (C-C motif) ligand 3-like 1
CCL5 chemokine (C-C motif) ligand 5
CD14 CD14 molecule
CD2 CD2 molecule
CD36 CD36 molecule (thrombospondin receptor)
CD40LG CD40 ligand
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CMC2 C-x(9)-C motif containing 2
CR1 complement component (3b/4b) receptor 1 (Knops blood group)
CRP C-reactive protein, pentraxin-related
CXCL10 chemokine (C-X-C motif) ligand 10
CXCL8 chemokine (C-X-C motif) ligand 8
CXCL9 chemokine (C-X-C motif) ligand 9
CXCR3 chemokine (C-X-C motif) receptor 3
CYBB cytochrome b-245, beta polypeptide
DDC dopa decarboxylase (aromatic L-amino acid decarboxylase)
DDX39B DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B
DECR1 2,4-dienoyl CoA reductase 1, mitochondrial
DHPS deoxyhypusine synthase
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
EBNA1BP2 EBNA1 binding protein 2
EIF5A eukaryotic translation initiation factor 5A
ELANE elastase, neutrophil expressed
ENOSF1 enolase superfamily member 1
EPCAM epithelial cell adhesion molecule
FCGR2A Fc fragment of IgG, low affinity IIa, receptor (CD32)
FCGR2B Fc fragment of IgG, low affinity IIb, receptor (CD32)
FCGR2C Fc fragment of IgG, low affinity IIc, receptor for (CD32) (gene/pseudogene)
FCGR3A Fc fragment of IgG, low affinity IIIa, receptor (CD16a)
FCGR3B Fc fragment of IgG, low affinity IIIb, receptor (CD16b)
FCN2 ficolin (collagen/fibrinogen domain containing lectin) 2
FOXO3 forkhead box O3
FREM3 FRAS1 related extracellular matrix 3
FTH1 ferritin, heavy polypeptide 1
G6PD glucose-6-phosphate dehydrogenase
GABPA GA binding protein transcription factor, alpha subunit 60kDa
GEM GTP binding protein overexpressed in skeletal muscle
GNB3 guanine nucleotide binding protein (G protein), beta polypeptide 3
GRK2 G protein-coupled receptor kinase 2
GSTP1 glutathione S-transferase pi 1
GSTT1 glutathione S-transferase theta 1
GYPA glycophorin A (MNS blood group)
GYPB glycophorin B (MNS blood group)
GYPE glycophorin E (MNS blood group)
GZMB granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)
HAMP hepcidin antimicrobial peptide
HBA1 hemoglobin, alpha 1
HBA2 hemoglobin, alpha 2
HDGFL2 HDGF like 2
HLA-A major histocompatibility complex, class I, A
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
HMGB1 high mobility group box 1
HMOX1 heme oxygenase 1
HP haptoglobin
HSPA4 heat shock 70kDa protein 4
ICAM1 intercellular adhesion molecule 1
IFNAR1 interferon (alpha, beta and omega) receptor 1
IFNB1 interferon, beta 1, fibroblast
IFNG interferon, gamma
IFNGR1 interferon gamma receptor 1
IL10 interleukin 10
IL10RA interleukin 10 receptor, alpha
IL12B interleukin 12B
IL13 interleukin 13
IL1A interleukin 1, alpha
IL1B interleukin 1, beta
IL1RN interleukin 1 receptor antagonist
IL2 interleukin 2
IL22 interleukin 22
IL23R interleukin 23 receptor
IL3 interleukin 3
IL4 interleukin 4
IL6 interleukin 6
IL9 interleukin 9
IRAK4 interleukin-1 receptor-associated kinase 4
IRF1 interferon regulatory factor 1
ISYNA1 inositol-3-phosphate synthase 1
KIR2DL1 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 1
KIR2DL3 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 3
KIR2DS2 killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 2
KIR3DL1 killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 1
LAIR1 leukocyte-associated immunoglobulin-like receptor 1
LANCL1 LanC lantibiotic synthetase component C-like 1 (bacterial)
LGALS2 lectin, galactoside-binding, soluble, 2
LILRB1 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1
LMLN leishmanolysin-like (metallopeptidase M8 family)
LTA lymphotoxin alpha
MAPK1 mitogen-activated protein kinase 1
MBL2 mannose-binding lectin (protein C) 2, soluble
MCCC1 methylcrotonoyl-CoA carboxylase 1 (alpha)
MECP2 methyl CpG binding protein 2
MIF macrophage migration inhibitory factor (glycosylation-inhibiting factor)
MIP major intrinsic protein of lens fiber
MSMB microseminoprotein, beta-
MST1 macrophage stimulating 1
MXD1 MAX dimerization protein 1
NFE2L2 nuclear factor, erythroid 2-like 2
NOS2 nitric oxide synthase 2, inducible
OR10A4 olfactory receptor, family 10, subfamily A, member 4
PCSK9 proprotein convertase subtilisin/kexin type 9
PECAM1 platelet/endothelial cell adhesion molecule 1
POU2F1 POU class 2 homeobox 1
PPARG peroxisome proliferator-activated receptor gamma
PROCR protein C receptor, endothelial
PRRC2A proline-rich coiled-coil 2A
PSMB9 proteasome (prosome, macropain) subunit, beta type, 9
PSMD7 proteasome (prosome, macropain) 26S subunit, non-ATPase, 7
RABEPK Rab9 effector protein with kelch motifs
RBM45 RNA binding motif protein 45
RECQL4 RecQ protein-like 4
RGS2 regulator of G-protein signaling 2
RHOF ras homolog family member F (in filopodia)
RNASE3 ribonuclease, RNase A family, 3
RNF34 ring finger protein 34, E3 ubiquitin protein ligase
RPSA ribosomal protein SA
RTN3 reticulon 3
SDC1 syndecan 1
SELE selectin E
SLC22A1 solute carrier family 22 (organic cation transporter), member 1
SLC4A1 solute carrier family 4 (anion exchanger), member 1 (Diego blood group)
SMN1 survival of motor neuron 1, telomeric
SMN2 survival of motor neuron 2, centromeric
SOD1 superoxide dismutase 1, soluble
TAC1 tachykinin, precursor 1
TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
TGFB1 transforming growth factor, beta 1
TIRAP toll-interleukin 1 receptor (TIR) domain containing adaptor protein
TLR1 toll-like receptor 1
TLR2 toll-like receptor 2
TLR4 toll-like receptor 4
TLR6 toll-like receptor 6
TLR9 toll-like receptor 9
TMPRSS13 transmembrane protease, serine 13
TNF tumor necrosis factor
TP63 tumor protein p63
TPT1 tumor protein, translationally-controlled 1
TREM1 triggering receptor expressed on myeloid cells 1
USP38 ubiquitin specific peptidase 38
VCAM1 vascular cell adhesion molecule 1