Constitutive Signaling by AKT1 E17K in Cancer Gene Set

Dataset Reactome Pathways 2024
Category structural or functional annotations
Type pathway
External Link https://reactome.org/PathwayBrowser/#/R-HSA-5674400
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Genes

26 proteins participating in the Constitutive Signaling by AKT1 E17K in Cancer pathway from the Reactome Pathways 2024 dataset.

Symbol Name
AKT1 v-akt murine thymoma viral oncogene homolog 1
AKT1S1 AKT1 substrate 1 (proline-rich)
AKT2 v-akt murine thymoma viral oncogene homolog 2
AKT3 v-akt murine thymoma viral oncogene homolog 3
BAD BCL2-associated agonist of cell death
CASP9 caspase 9, apoptosis-related cysteine peptidase
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CHUK conserved helix-loop-helix ubiquitous kinase
CREB1 cAMP responsive element binding protein 1
FOXO1 forkhead box O1
FOXO3 forkhead box O3
FOXO4 forkhead box O4
FOXO6 forkhead box O6
GSK3A glycogen synthase kinase 3 alpha
GSK3B glycogen synthase kinase 3 beta
MAPKAP1 mitogen-activated protein kinase associated protein 1
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MLST8 MTOR associated protein, LST8 homolog (S. cerevisiae)
MTOR mechanistic target of rapamycin (serine/threonine kinase)
NR4A1 nuclear receptor subfamily 4, group A, member 1
PDPK1 3-phosphoinositide dependent protein kinase 1
PRR5 proline rich 5 (renal)
RICTOR RPTOR independent companion of MTOR, complex 2
RPS6KB2 ribosomal protein S6 kinase, 70kDa, polypeptide 2
TSC2 tuberous sclerosis 2