Cor Pulmonale Gene Set

Dataset DisGeNET Gene-Disease Associations
Category disease or phenotype associations
Type disease
Description A congestive heart failure that involves a failure of the right side of the heart and is characterized by an enlargement of the right ventricle of the heart as a response to increased resistance or high blood pressure in the lungs. (Human Disease Ontology, DOID_8515)
External Link https://www.disgenet.org/browser/0/1/0/C0034072
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Genes

23 genes associated with the disease Cor Pulmonale in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.

Symbol Name
ACE2 angiotensin I converting enzyme 2
AGTR1 angiotensin II receptor, type 1
AHSP alpha hemoglobin stabilizing protein
AKT1 v-akt murine thymoma viral oncogene homolog 1
ANGPT2 angiopoietin 2
BTK Bruton agammaglobulinemia tyrosine kinase
CA5A carbonic anhydrase VA, mitochondrial
CAV1 caveolin 1, caveolae protein, 22kDa
CAV2 caveolin 2
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)
CHRNA3 cholinergic receptor, nicotinic, alpha 3 (neuronal)
CHRNA5 cholinergic receptor, nicotinic, alpha 5 (neuronal)
CHRNB4 cholinergic receptor, nicotinic, beta 4 (neuronal)
CRP C-reactive protein, pentraxin-related
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
ELANE elastase, neutrophil expressed
FCGR2A Fc fragment of IgG, low affinity IIa, receptor (CD32)
FLNA filamin A, alpha
IL6 interleukin 6
NOS3 nitric oxide synthase 3 (endothelial cell)
SELENON selenoprotein N
TGFB1 transforming growth factor, beta 1
VPS51 vacuolar protein sorting 51 homolog (S. cerevisiae)