Craniopharyngioma Gene Set

Dataset DISEASES Text-mining Gene-Disease Association Evidence Scores 2025
Category disease or phenotype associations
Type disease
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Genes

252 genes co-occuring with the disease Craniopharyngioma in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores 2025 dataset.

Symbol Name Standardized Value
POMC proopiomelanocortin 2.907
PRL prolactin 2.733
BRAF B-Raf proto-oncogene, serine/threonine kinase 2.709
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa 2.611
AVP arginine vasopressin 2.6
IGF1 insulin-like growth factor 1 (somatomedin C) 2.549
PROP1 PROP paired-like homeobox 1 2.427
TBX19 T-box 19 2.394
GH1 growth hormone 1 2.308
HESX1 HESX homeobox 1 2.2
GH2 growth hormone 2 2.199
SHH sonic hedgehog 2.124
TRH thyrotropin-releasing hormone 2.121
CSH1 chorionic somatomammotropin hormone 1 (placental lactogen) 2.12
GHRH growth hormone releasing hormone 2.103
CSH2 chorionic somatomammotropin hormone 2 2.096
INS insulin 2.079
KIAA1549 KIAA1549 2.076
OXT oxytocin/neurophysin I prepropeptide 2.064
ESX1 ESX homeobox 1 2.045
POU1F1 POU class 1 homeobox 1 2.044
LEP leptin 2.04
GHRL ghrelin/obestatin prepropeptide 1.991
SYP synaptophysin 1.962
LHX3 LIM homeobox 3 1.904
NF1 neurofibromin 1 1.879
IGFBP3 insulin-like growth factor binding protein 3 1.867
SST somatostatin 1.862
IDH1 isocitrate dehydrogenase 1 (NADP+), soluble 1.846
TP53 tumor protein p53 1.838
SMARCB1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1 1.832
GHR growth hormone receptor 1.829
MC4R melanocortin 4 receptor 1.744
LHX4 LIM homeobox 4 1.724
GFAP glial fibrillary acidic protein 1.724
EGFR epidermal growth factor receptor 1.71
SOX2 SRY (sex determining region Y)-box 2 1.708
NKX2-1 NK2 homeobox 1 1.696
GNRH1 gonadotropin-releasing hormone 1 (luteinizing-releasing hormone) 1.694
USP8 ubiquitin specific peptidase 8 1.685
CRH corticotropin releasing hormone 1.678
FAM131B family with sequence similarity 131, member B 1.678
HCRT hypocretin (orexin) neuropeptide precursor 1.674
GCG glucagon 1.673
AGRP agouti related neuropeptide 1.671
IFNA2 interferon, alpha 2 1.666
IFNA16 interferon, alpha 16 1.655
IFNA10 interferon, alpha 10 1.654
IFNA21 interferon, alpha 21 1.654
IFNA14 interferon, alpha 14 1.654
IFNA7 interferon, alpha 7 1.654
IFNA6 interferon, alpha 6 1.653
IFNA8 interferon, alpha 8 1.653
IFNA5 interferon, alpha 5 1.652
IFNA13 interferon, alpha 13 1.651
IFNA4 interferon, alpha 4 1.649
IFNA17 interferon, alpha 17 1.645
IFNA1 interferon, alpha 1 1.625
MGMT O-6-methylguanine-DNA methyltransferase 1.618
H3-3A H3.3 histone A 1.614
RPH3A rabphilin 3A 1.613
NR5A1 nuclear receptor subfamily 5, group A, member 1 1.608
AIP aryl hydrocarbon receptor interacting protein 1.581
PTCH1 patched 1 1.579
USP48 ubiquitin specific peptidase 48 1.57
PYY peptide YY 1.561
SIM1 single-minded family bHLH transcription factor 1 1.556
CDKN2A cyclin-dependent kinase inhibitor 2A 1.527
NF2 neurofibromin 2 (merlin) 1.516
NPY neuropeptide Y 1.504
KRT7 keratin 7, type II 1.497
AFP alpha-fetoprotein 1.492
GPR101 G protein-coupled receptor 101 1.491
KRT8 keratin 8, type II 1.485
GHSR growth hormone secretagogue receptor 1.482
ATRX alpha thalassemia/mental retardation syndrome X-linked 1.475
CD274 CD274 molecule 1.465
GFRA2 GDNF family receptor alpha 2 1.464
LEPR leptin receptor 1.456
IL6 interleukin 6 1.45
IDH2 isocitrate dehydrogenase 2 (NADP+), mitochondrial 1.449
MEN1 multiple endocrine neoplasia I 1.446
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha 1.442
AKT1 v-akt murine thymoma viral oncogene homolog 1 1.441
AXIN2 axin 2 1.44
SOX9 SRY (sex determining region Y)-box 9 1.438
WDR89 WD repeat domain 89 1.438
PDGFRA platelet-derived growth factor receptor, alpha polypeptide 1.427
CD276 CD276 molecule 1.412
CD68 CD68 molecule 1.412
LEF1 lymphoid enhancer-binding factor 1 1.406
TSHB thyroid stimulating hormone, beta 1.397
GHRHR growth hormone releasing hormone receptor 1.382
GNAS GNAS complex locus 1.379
FSHB follicle stimulating hormone, beta polypeptide 1.373
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A 1.37
ODAM odontogenic, ameloblast asssociated 1.356
H3-3B H3.3 histone B 1.354
RNF130 ring finger protein 130 1.351
ENAM enamelin 1.346
CHGA chromogranin A 1.344
MYCN v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog 1.344
BMP4 bone morphogenetic protein 4 1.34
CD1A CD1a molecule 1.339
SSTR2 somatostatin receptor 2 1.338
CD1B CD1b molecule 1.332
H3C3 H3 clustered histone 3 1.325
CD34 CD34 molecule 1.322
FGFR1 fibroblast growth factor receptor 1 1.32
CTLA4 cytotoxic T-lymphocyte-associated protein 4 1.318
CD1E CD1e molecule 1.317
MAP2K1 mitogen-activated protein kinase kinase 1 1.31
CABLES1 Cdk5 and Abl enzyme substrate 1 1.309
GLI2 GLI family zinc finger 2 1.304
KRT20 keratin 20, type I 1.303
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1) 1.301
PITX1 paired-like homeodomain 1 1.299
MYC v-myc avian myelocytomatosis viral oncogene homolog 1.293
ENO2 enolase 2 (gamma, neuronal) 1.289
KBTBD4 kelch repeat and BTB (POZ) domain containing 4 1.287
SMARCA4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 1.284
GLI1 GLI family zinc finger 1 1.284
KRT5 keratin 5, type II 1.28
MTOR mechanistic target of rapamycin (serine/threonine kinase) 1.279
SSTR5 somatostatin receptor 5 1.279
ADAMDEC1 ADAM-like, decysin 1 1.278
POU5F1 POU class 5 homeobox 1 1.272
PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma 1.267
TGFB1 transforming growth factor, beta 1 1.264
FGF8 fibroblast growth factor 8 (androgen-induced) 1.255
EWSR1 EWS RNA-binding protein 1 1.247
H3C6 H3 clustered histone 6 1.246
MCM6 minichromosome maintenance complex component 6 1.246
GFRA3 GDNF family receptor alpha 3 1.241
SOX3 SRY (sex determining region Y)-box 3 1.239
ALB albumin 1.238
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta 1.238
TERT telomerase reverse transcriptase 1.237
PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta 1.235
PRKAR1A protein kinase, cAMP-dependent, regulatory, type I, alpha 1.233
COL8A1 collagen, type VIII, alpha 1 1.233
CDH1 cadherin 1, type 1, E-cadherin (epithelial) 1.233
PROM1 prominin 1 1.23
H3C2 H3 clustered histone 2 1.227
PTEN phosphatase and tensin homolog 1.226
FDCSP follicular dendritic cell secreted protein 1.223
CD1C CD1c molecule 1.218
RAX retina and anterior neural fold homeobox 1.214
GNRHR gonadotropin-releasing hormone receptor 1.208
WNT4 wingless-type MMTV integration site family, member 4 1.206
KISS1 KiSS-1 metastasis-suppressor 1.205
MMP20 matrix metallopeptidase 20 1.2
HNF4A hepatocyte nuclear factor 4, alpha 1.2
EGF epidermal growth factor 1.197
PCSK1 proprotein convertase subtilisin/kexin type 1 1.192
OLIG2 oligodendrocyte lineage transcription factor 2 1.191
CD1D CD1d molecule 1.188
OTX2 orthodenticle homeobox 2 1.186
CD207 CD207 molecule, langerin 1.184
CRP C-reactive protein, pentraxin-related 1.183
H3C12 H3 clustered histone 12 1.181
ERBB2 erb-b2 receptor tyrosine kinase 2 1.181
FGF4 fibroblast growth factor 4 1.181
RIMS1 regulating synaptic membrane exocytosis 1 1.179
FSCN1 fascin actin-bundling protein 1 1.173
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) 1.173
CD8A CD8a molecule 1.169
S100A2 S100 calcium binding protein A2 1.165
SUFU suppressor of fused homolog (Drosophila) 1.164
ACVR1 activin A receptor, type I 1.157
MC3R melanocortin 3 receptor 1.155
RTRAF RNA transcription, translation and transport factor 1.152
AMELX amelogenin, X-linked 1.152
FGF10 fibroblast growth factor 10 1.15
NTSR1 neurotensin receptor 1 (high affinity) 1.148
COL6A2 collagen, type VI, alpha 2 1.145
PDCD1 programmed cell death 1 1.145
NRAS neuroblastoma RAS viral (v-ras) oncogene homolog 1.141
CARTPT CART prepropeptide 1.139
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) 1.133
CD99L2 CD99 molecule-like 2 1.129
HSD11B1 hydroxysteroid (11-beta) dehydrogenase 1 1.128
COL6A3 collagen, type VI, alpha 3 1.128
S100B S100 calcium binding protein B 1.124
PITX2 paired-like homeodomain 2 1.122
TRAF7 TNF receptor-associated factor 7, E3 ubiquitin protein ligase 1.12
CD44 CD44 molecule (Indian blood group) 1.118
CXCL12 chemokine (C-X-C motif) ligand 12 1.118
IGSF1 immunoglobulin superfamily, member 1 1.117
WNT5A wingless-type MMTV integration site family, member 5A 1.117
NCAM1 neural cell adhesion molecule 1 1.115
MYBL1 v-myb avian myeloblastosis viral oncogene homolog-like 1 1.115
CRYM crystallin, mu 1.113
ANOS1 anosmin 1 1.108
IGF2 insulin-like growth factor 2 1.104
YAP1 Yes-associated protein 1 1.101
GLI3 GLI family zinc finger 3 1.1
FGF18 fibroblast growth factor 18 1.098
LGALS3 lectin, galactoside-binding, soluble, 3 1.097
FGF3 fibroblast growth factor 3 1.093
KRT19 keratin 19, type I 1.091
CLCN6 chloride channel, voltage-sensitive 6 1.09
FGF9 fibroblast growth factor 9 1.089
GAN gigaxonin 1.089
VIT vitrin 1.085
ALK anaplastic lymphoma receptor tyrosine kinase 1.085
CD99 CD99 molecule 1.084
NES nestin 1.084
AXIN1 axin 1 1.084
MMP12 matrix metallopeptidase 12 1.081
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) 1.079
GLP1R glucagon-like peptide 1 receptor 1.074
SIRAL1 SIR2 antiphage like 1 1.073
PXDNL peroxidasin-like 1.072
PXDN peroxidasin 1.07
CXCR4 chemokine (C-X-C motif) receptor 4 1.068
ALPP alkaline phosphatase, placental 1.068
RET ret proto-oncogene 1.062
AMER3 APC membrane recruitment protein 3 1.062
FGF20 fibroblast growth factor 20 1.056
BCL2 B-cell CLL/lymphoma 2 1.055
FGF17 fibroblast growth factor 17 1.054
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 1.054
CLDN1 claudin 1 1.053
QKI QKI, KH domain containing, RNA binding 1.051
TBC1D32 TBC1 domain family, member 32 1.049
SRGAP3 SLIT-ROBO Rho GTPase activating protein 3 1.048
SHBG sex hormone-binding globulin 1.044
NAB2 NGFI-A binding protein 2 (EGR1 binding protein 2) 1.044
TNF tumor necrosis factor 1.044
KRAS Kirsten rat sarcoma viral oncogene homolog 1.044
MMP9 matrix metallopeptidase 9 1.043
FGF6 fibroblast growth factor 6 1.042
FOXR2 forkhead box R2 1.038
KRT14 keratin 14, type I 1.035
ESR1 estrogen receptor 1 1.033
ARAF A-Raf proto-oncogene, serine/threonine kinase 1.029
KRT13 keratin 13, type I 1.028
FGF22 fibroblast growth factor 22 1.026
FGF16 fibroblast growth factor 16 1.025
GPT glutamic-pyruvate transaminase (alanine aminotransferase) 1.019
IGF1R insulin-like growth factor 1 receptor 1.019
IGFBP1 insulin-like growth factor binding protein 1 1.018
FGF5 fibroblast growth factor 5 1.017
ATRNL1 attractin-like 1 1.011
EPCAM epithelial cell adhesion molecule 1.011
CCND1 cyclin D1 1.009
CD4 CD4 molecule 1.008
TMSB4X thymosin beta 4, X-linked 1.006
IL1A interleukin 1, alpha 1.005
IFNG interferon, gamma 1.0
CDK4 cyclin-dependent kinase 4 1.0