Craniosynostosis Gene Set

Dataset DISEASES Text-mining Gene-Disease Association Evidence Scores 2025
Category disease or phenotype associations
Type disease
Description A synostosis that results_in premature fusion located_in skull. (Human Disease Ontology, DOID_2340)
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Genes

597 genes co-occuring with the disease Craniosynostosis in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores 2025 dataset.

Symbol Name Standardized Value
FGFR2 fibroblast growth factor receptor 2 3.682
FGFR3 fibroblast growth factor receptor 3 3.354
MSX2 msh homeobox 2 3.192
FGFR1 fibroblast growth factor receptor 1 3.113
TWIST1 twist family bHLH transcription factor 1 3.02
EFNB1 ephrin-B1 2.969
RUNX2 runt-related transcription factor 2 2.817
TCF12 transcription factor 12 2.777
NELL1 NEL-like 1 (chicken) 2.654
RAB23 RAB23, member RAS oncogene family 2.634
IL11RA interleukin 11 receptor, alpha 2.626
ALX4 ALX homeobox 4 2.614
FGF8 fibroblast growth factor 8 (androgen-induced) 2.568
IHH indian hedgehog 2.559
POR P450 (cytochrome) oxidoreductase 2.553
FGF10 fibroblast growth factor 10 2.532
SMAD6 SMAD family member 6 2.52
ALPL alkaline phosphatase, liver/bone/kidney 2.504
FGF9 fibroblast growth factor 9 2.484
FGF13 fibroblast growth factor 13 2.454
PHEX phosphate regulating endopeptidase homolog, X-linked 2.45
FGF3 fibroblast growth factor 3 2.449
ARID1B AT rich interactive domain 1B (SWI1-like) 2.444
FGF18 fibroblast growth factor 18 2.441
FGF4 fibroblast growth factor 4 2.433
MSX1 msh homeobox 1 2.432
GLI3 GLI family zinc finger 3 2.415
CYP26B1 cytochrome P450, family 26, subfamily B, polypeptide 1 2.411
FGF7 fibroblast growth factor 7 2.407
SP7 Sp7 transcription factor 2.384
BMP2 bone morphogenetic protein 2 2.382
EFNA4 ephrin-A4 2.357
FGF2 fibroblast growth factor 2 (basic) 2.356
IFT43 intraflagellar transport 43 2.347
FGF20 fibroblast growth factor 20 2.342
FGF16 fibroblast growth factor 16 2.342
FGF6 fibroblast growth factor 6 2.339
FGF22 fibroblast growth factor 22 2.338
FGF17 fibroblast growth factor 17 2.337
RECQL4 RecQ protein-like 4 2.33
FREM1 FRAS1 related extracellular matrix 1 2.318
BGLAP bone gamma-carboxyglutamate (gla) protein 2.315
FGF5 fibroblast growth factor 5 2.314
WDR19 WD repeat domain 19 2.309
WDR35 WD repeat domain 35 2.306
AXIN2 axin 2 2.299
GLI1 GLI family zinc finger 1 2.273
FBN1 fibrillin 1 2.273
BBS9 Bardet-Biedl syndrome 9 2.27
IFT122 intraflagellar transport 122 2.241
BMP4 bone morphogenetic protein 4 2.233
FGFR4 fibroblast growth factor receptor 4 2.233
FGF23 fibroblast growth factor 23 2.231
NOG noggin 2.229
ZIC1 Zic family member 1 2.225
SOX9 SRY (sex determining region Y)-box 9 2.217
SHH sonic hedgehog 2.213
TGFBR1 transforming growth factor, beta receptor 1 2.201
TGFBR2 transforming growth factor, beta receptor II (70/80kDa) 2.175
DLX5 distal-less homeobox 5 2.167
IBSP integrin-binding sialoprotein 2.16
FGFRL1 fibroblast growth factor receptor-like 1 2.155
CYP21A2 cytochrome P450, family 21, subfamily A, polypeptide 2 2.142
TWIST2 twist family bHLH transcription factor 2 2.108
TGFB3 transforming growth factor, beta 3 2.1
CDC45 cell division cycle 45 2.099
FGF1 fibroblast growth factor 1 (acidic) 2.07
ALX3 ALX homeobox 3 2.069
VPREB1 pre-B lymphocyte 1 2.068
COL2A1 collagen, type II, alpha 1 2.067
CYP17A1 cytochrome P450, family 17, subfamily A, polypeptide 1 2.066
ERF Ets2 repressor factor 2.066
TGFB1 transforming growth factor, beta 1 2.064
PRRX1 paired related homeobox 1 2.057
AHDC1 AT hook, DNA binding motif, containing 1 2.051
CYP51A1 cytochrome P450, family 51, subfamily A, polypeptide 1 2.023
PTCH1 patched 1 2.017
EPHA4 EPH receptor A4 2.015
SPP1 secreted phosphoprotein 1 2.001
FAM20C family with sequence similarity 20, member C 1.956
EPHA1 EPH receptor A1 1.953
IL11 interleukin 11 1.952
SLC25A24 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 24 1.943
LRIT3 leucine-rich repeat, immunoglobulin-like and transmembrane domains 3 1.943
COL1A1 collagen, type I, alpha 1 1.936
CTSK cathepsin K 1.935
TGFB2 transforming growth factor, beta 2 1.932
IFT140 intraflagellar transport 140 1.924
SOST sclerostin 1.922
IRF6 interferon regulatory factor 6 1.919
FRS2 fibroblast growth factor receptor substrate 2 1.917
GDF6 growth differentiation factor 6 1.908
BMPR1A bone morphogenetic protein receptor, type IA 1.905
SPECC1L sperm antigen with calponin homology and coiled-coil domains 1-like 1.902
PTH parathyroid hormone 1.902
COLEC11 collectin sub-family member 11 1.9
TCOF1 Treacher Collins-Franceschetti syndrome 1 1.895
BMP7 bone morphogenetic protein 7 1.893
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa 1.88
ALX1 ALX homeobox 1 1.873
MEGF8 multiple EGF-like-domains 8 1.846
CYP26A1 cytochrome P450, family 26, subfamily A, polypeptide 1 1.845
BMP3 bone morphogenetic protein 3 1.837
DMP1 dentin matrix acidic phosphoprotein 1 1.82
LRP5 low density lipoprotein receptor-related protein 5 1.798
TNFSF11 tumor necrosis factor (ligand) superfamily, member 11 1.782
IFT52 intraflagellar transport 52 1.778
DUSP6 dual specificity phosphatase 6 1.778
DLX6 distal-less homeobox 6 1.777
PTPN11 protein tyrosine phosphatase, non-receptor type 11 1.776
WNT1 wingless-type MMTV integration site family, member 1 1.761
SOX6 SRY (sex determining region Y)-box 6 1.756
HAND2 heart and neural crest derivatives expressed 2 1.752
ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1 1.748
EFNA2 ephrin-A2 1.746
PTHLH parathyroid hormone-like hormone 1.738
COL1A2 collagen, type I, alpha 2 1.732
MAPK3 mitogen-activated protein kinase 3 1.731
TTC21B tetratricopeptide repeat domain 21B 1.723
CYB5A cytochrome b5 type A (microsomal) 1.713
JAG1 jagged 1 1.712
GDF5 growth differentiation factor 5 1.701
GLI2 GLI family zinc finger 2 1.691
MEPE matrix extracellular phosphoglycoprotein 1.688
LMX1B LIM homeobox transcription factor 1, beta 1.684
PTH1R parathyroid hormone 1 receptor 1.679
EVC2 Ellis van Creveld syndrome 2 1.679
IL6ST interleukin 6 signal transducer 1.673
SMAD3 SMAD family member 3 1.673
EMP1 epithelial membrane protein 1 1.665
SLC34A3 solute carrier family 34 (type II sodium/phosphate cotransporter), member 3 1.664
ZNF462 zinc finger protein 462 1.658
ZNF341 zinc finger protein 341 1.655
EN1 engrailed homeobox 1 1.654
WNT3A wingless-type MMTV integration site family, member 3A 1.652
CRTAP cartilage associated protein 1.648
DYNC2H1 dynein, cytoplasmic 2, heavy chain 1 1.644
BCL11B B-cell CLL/lymphoma 11B (zinc finger protein) 1.642
ACAN aggrecan 1.641
CHRD chordin 1.639
CHD7 chromodomain helicase DNA binding protein 7 1.634
ORC4 origin recognition complex, subunit 4 1.625
COL10A1 collagen, type X, alpha 1 1.624
B3GAT3 beta-1,3-glucuronyltransferase 3 1.622
ACVR1 activin A receptor, type I 1.619
IGF1 insulin-like growth factor 1 (somatomedin C) 1.619
CYP19A1 cytochrome P450, family 19, subfamily A, polypeptide 1 1.616
SIX2 SIX homeobox 2 1.614
SEC24D SEC24 family member D 1.612
SPRY2 sprouty homolog 2 (Drosophila) 1.612
DLX2 distal-less homeobox 2 1.608
EFNB2 ephrin-B2 1.607
PAX9 paired box 9 1.604
KIF3A kinesin family member 3A 1.6
KL klotho 1.598
KAT6A K(lysine) acetyltransferase 6A 1.597
SMAD2 SMAD family member 2 1.596
ADAMTSL4 ADAMTS-like 4 1.596
AXIN1 axin 1 1.584
SMO smoothened, frizzled class receptor 1.584
TBX6 T-box 6 1.574
GPC3 glypican 3 1.57
NKX3-2 NK3 homeobox 2 1.567
MASP1 mannan-binding lectin serine peptidase 1 (C4/C2 activating component of Ra-reactive factor) 1.564
IFT80 intraflagellar transport 80 1.563
TBX1 T-box 1 1.556
SMAD9 SMAD family member 9 1.554
NSD1 nuclear receptor binding SET domain protein 1 1.546
COLEC10 collectin sub-family member 10 (C-type lectin) 1.545
SMAD4 SMAD family member 4 1.545
FLNA filamin A, alpha 1.541
KAT6B K(lysine) acetyltransferase 6B 1.539
CYB5B cytochrome b5 type B (outer mitochondrial membrane) 1.539
SKI SKI proto-oncogene 1.533
PDGFRA platelet-derived growth factor receptor, alpha polypeptide 1.53
TRIM8 tripartite motif containing 8 1.528
PAX3 paired box 3 1.528
FUZ fuzzy planar cell polarity protein 1.522
AKT1 v-akt murine thymoma viral oncogene homolog 1 1.516
MAP2K1 mitogen-activated protein kinase kinase 1 1.513
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b 1.508
NPPC natriuretic peptide C 1.506
GNAS GNAS complex locus 1.503
KMT2D lysine (K)-specific methyltransferase 2D 1.502
SHOC2 soc-2 suppressor of clear homolog (C. elegans) 1.501
DHCR7 7-dehydrocholesterol reductase 1.499
PPIG peptidylprolyl isomerase G (cyclophilin G) 1.496
SLC34A1 solute carrier family 34 (type II sodium/phosphate cotransporter), member 1 1.493
CYP26C1 cytochrome P450, family 26, subfamily C, polypeptide 1 1.492
SOS1 son of sevenless homolog 1 (Drosophila) 1.492
EXT2 exostosin glycosyltransferase 2 1.49
ACP5 acid phosphatase 5, tartrate resistant 1.49
SPRY1 sprouty homolog 1, antagonist of FGF signaling (Drosophila) 1.486
SQLE squalene epoxidase 1.484
BMPR1B bone morphogenetic protein receptor, type IB 1.484
KIF7 kinesin family member 7 1.479
PITX2 paired-like homeodomain 2 1.471
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 1.47
ZP2 zona pellucida glycoprotein 2 (sperm receptor) 1.468
GMNN geminin, DNA replication inhibitor 1.468
NFIX nuclear factor I/X (CCAAT-binding transcription factor) 1.464
EBP emopamil binding protein (sterol isomerase) 1.463
DOCK8 dedicator of cytokinesis 8 1.462
FN1 fibronectin 1 1.461
NFIA nuclear factor I/A 1.461
GRHL3 grainyhead-like 3 (Drosophila) 1.457
RECQL5 RecQ protein-like 5 1.454
SUFU suppressor of fused homolog (Drosophila) 1.453
BARX2 BARX homeobox 2 1.453
RSPRY1 ring finger and SPRY domain containing 1 1.443
DKK1 dickkopf WNT signaling pathway inhibitor 1 1.443
MMP23B matrix metallopeptidase 23B 1.442
SMURF1 SMAD specific E3 ubiquitin protein ligase 1 1.438
IGF1R insulin-like growth factor 1 receptor 1.438
EGF epidermal growth factor 1.436
EFTUD2 elongation factor Tu GTP binding domain containing 2 1.432
DHH desert hedgehog 1.431
WNT5A wingless-type MMTV integration site family, member 5A 1.428
P4HB prolyl 4-hydroxylase, beta polypeptide 1.427
BMP6 bone morphogenetic protein 6 1.427
LTBP3 latent transforming growth factor beta binding protein 3 1.427
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha) 1.426
HSD3B2 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2 1.426
GAPDH glyceraldehyde-3-phosphate dehydrogenase 1.425
TFAP2B transcription factor AP-2 beta (activating enhancer binding protein 2 beta) 1.425
ANKH ANKH inorganic pyrophosphate transport regulator 1.414
C2CD3 C2 calcium-dependent domain containing 3 1.409
ALPP alkaline phosphatase, placental 1.405
TSHR thyroid stimulating hormone receptor 1.403
EVC Ellis van Creveld protein 1.402
IFT172 intraflagellar transport 172 1.402
IFITM5 interferon induced transmembrane protein 5 1.4
SFRP4 secreted frizzled-related protein 4 1.399
OFD1 oral-facial-digital syndrome 1 1.398
LTBP2 latent transforming growth factor beta binding protein 2 1.398
POMC proopiomelanocortin 1.397
PGM3 phosphoglucomutase 3 1.397
POLR1D polymerase (RNA) I polypeptide D, 16kDa 1.394
GRB2 growth factor receptor-bound protein 2 1.394
GPC1 glypican 1 1.393
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha 1.393
FREM2 FRAS1 related extracellular matrix protein 2 1.392
PJA1 praja ring finger 1, E3 ubiquitin protein ligase 1.391
BMP1 bone morphogenetic protein 1 1.383
SOX10 SRY (sex determining region Y)-box 10 1.381
GDF2 growth differentiation factor 2 1.38
SOX5 SRY (sex determining region Y)-box 5 1.379
SCARF2 scavenger receptor class F, member 2 1.379
FKBP10 FK506 binding protein 10, 65 kDa 1.378
NOTCH2 notch 2 1.378
SPRY3 sprouty homolog 3 (Drosophila) 1.378
RECQL RecQ helicase-like 1.376
OSM oncostatin M 1.375
DVL1 dishevelled segment polarity protein 1 1.373
LRP6 low density lipoprotein receptor-related protein 6 1.373
PAX6 paired box 6 1.372
SPRY4 sprouty homolog 4 (Drosophila) 1.372
POSTN periostin, osteoblast specific factor 1.372
MYO1H myosin IH 1.371
IFT88 intraflagellar transport 88 1.368
GALNT3 polypeptide N-acetylgalactosaminyltransferase 3 1.368
HRAS Harvey rat sarcoma viral oncogene homolog 1.368
CDK13 cyclin-dependent kinase 13 1.363
ORC6 origin recognition complex, subunit 6 1.362
ACTB actin, beta 1.356
WNT10B wingless-type MMTV integration site family, member 10B 1.355
CTF1 cardiotrophin 1 1.355
VANGL2 VANGL planar cell polarity protein 2 1.353
FAM20B family with sequence similarity 20, member B 1.352
NPR2 natriuretic peptide receptor 2 1.352
SHOX2 short stature homeobox 2 1.349
PHOSPHO1 phosphatase, orphan 1 1.347
EPHB3 EPH receptor B3 1.346
KIAA0586 KIAA0586 1.346
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4 1.344
TCIRG1 T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 subunit A3 1.339
EPHB1 EPH receptor B1 1.339
PTH2R parathyroid hormone 2 receptor 1.336
MAF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog 1.333
PLS3 plastin 3 1.332
ALPG alkaline phosphatase, germ cell 1.332
IL6 interleukin 6 1.331
INTU inturned planar cell polarity protein 1.33
ELN elastin 1.328
SRY sex determining region Y 1.328
PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma 1.327
FGF12 fibroblast growth factor 12 1.324
OSR2 odd-skipped related transciption factor 2 1.323
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta 1.323
PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta 1.322
WNT9A wingless-type MMTV integration site family, member 9A 1.32
DLX3 distal-less homeobox 3 1.319
WIF1 WNT inhibitory factor 1 1.318
AMER1 APC membrane recruitment protein 1 1.318
ACTA2 actin, alpha 2, smooth muscle, aorta 1.318
NTRK1 neurotrophic tyrosine kinase, receptor, type 1 1.315
SIX3 SIX homeobox 3 1.315
MMP13 matrix metallopeptidase 13 1.313
LEF1 lymphoid enhancer-binding factor 1 1.312
BARX1 BARX homeobox 1 1.31
FRAS1 Fraser extracellular matrix complex subunit 1 1.309
LEMD3 LEM domain containing 3 1.308
RDH10 retinol dehydrogenase 10 (all-trans) 1.305
FOXP2 forkhead box P2 1.301
SMAD5 SMAD family member 5 1.298
CEP120 centrosomal protein 120kDa 1.297
STRA6 stimulated by retinoic acid 6 1.296
SPARC secreted protein, acidic, cysteine-rich (osteonectin) 1.29
SOX11 SRY (sex determining region Y)-box 11 1.289
COL3A1 collagen, type III, alpha 1 1.285
KDM6A lysine (K)-specific demethylase 6A 1.283
NF1 neurofibromin 1 1.283
SALL1 spalt-like transcription factor 1 1.28
ZIC2 Zic family member 2 1.277
SH3PXD2B SH3 and PX domains 2B 1.274
SATB2 SATB homeobox 2 1.273
ETV5 ets variant 5 1.273
NIPBL Nipped-B homolog (Drosophila) 1.273
MYH11 myosin, heavy chain 11, smooth muscle 1.272
DKK2 dickkopf WNT signaling pathway inhibitor 2 1.272
CYP27B1 cytochrome P450, family 27, subfamily B, polypeptide 1 1.267
ANKRD11 ankyrin repeat domain 11 1.266
HUWE1 HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase 1.265
LIF leukemia inhibitory factor 1.265
CLCN7 chloride channel, voltage-sensitive 7 1.263
INS insulin 1.263
WDPCP WD repeat containing planar cell polarity effector 1.262
STAR steroidogenic acute regulatory protein 1.261
ZIC4 Zic family member 4 1.261
FOXC1 forkhead box C1 1.259
WLS wntless Wnt ligand secretion mediator 1.258
WNT9B wingless-type MMTV integration site family, member 9B 1.257
CNTF ciliary neurotrophic factor 1.256
DONSON downstream neighbor of SON 1.254
TSPEAR thrombospondin-type laminin G domain and EAR repeats 1.253
WNT4 wingless-type MMTV integration site family, member 4 1.252
TP53 tumor protein p53 1.251
P3H1 prolyl 3-hydroxylase 1 1.251
RET ret proto-oncogene 1.247
HSD17B3 hydroxysteroid (17-beta) dehydrogenase 3 1.245
COL11A1 collagen, type XI, alpha 1 1.244
HNF4A hepatocyte nuclear factor 4, alpha 1.244
GREM2 gremlin 2, DAN family BMP antagonist 1.241
FDXR ferredoxin reductase 1.241
SHOX short stature homeobox 1.238
EP300 E1A binding protein p300 1.236
EXT1 exostosin glycosyltransferase 1 1.235
PLOD2 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 1.235
CYP11B1 cytochrome P450, family 11, subfamily B, polypeptide 1 1.234
ALPI alkaline phosphatase, intestinal 1.234
GAGE12C G antigen 12C 1.233
LMBR1 limb development membrane protein 1 1.232
HOXD13 homeobox D13 1.231
EFNB3 ephrin-B3 1.229
ZIC3 Zic family member 3 1.228
PITX1 paired-like homeodomain 1 1.224
FERD3L Fer3-like bHLH transcription factor 1.223
ALB albumin 1.223
TGIF2LX TGFB-induced factor homeobox 2-like, X-linked 1.222
FBN2 fibrillin 2 1.222
CYP1A2 cytochrome P450, family 1, subfamily A, polypeptide 2 1.221
BSX brain-specific homeobox 1.22
GLB1 galactosidase, beta 1 1.218
HS6ST1 heparan sulfate 6-O-sulfotransferase 1 1.218
BGN biglycan 1.217
TBX5 T-box 5 1.214
CYP11A1 cytochrome P450, family 11, subfamily A, polypeptide 1 1.213
MSMO1 methylsterol monooxygenase 1 1.211
TRAF7 TNF receptor-associated factor 7, E3 ubiquitin protein ligase 1.21
NEK1 NIMA-related kinase 1 1.205
AMBN ameloblastin (enamel matrix protein) 1.205
KRAS Kirsten rat sarcoma viral oncogene homolog 1.205
WNT6 wingless-type MMTV integration site family, member 6 1.205
WNT7B wingless-type MMTV integration site family, member 7B 1.204
HOXA2 homeobox A2 1.201
GSK3B glycogen synthase kinase 3 beta 1.199
WNT3 wingless-type MMTV integration site family, member 3 1.199
VAX1 ventral anterior homeobox 1 1.197
EPHA7 EPH receptor A7 1.196
IDUA iduronidase, alpha-L- 1.196
WNT16 wingless-type MMTV integration site family, member 16 1.192
SMAD7 SMAD family member 7 1.192
MESP2 mesoderm posterior basic helix-loop-helix transcription factor 2 1.19
B3GALT6 UDP-Gal:betaGal beta 1,3-galactosyltransferase polypeptide 6 1.189
WRN Werner syndrome, RecQ helicase-like 1.185
SLC25A41 solute carrier family 25, member 41 1.185
SLC2A10 solute carrier family 2 (facilitated glucose transporter), member 10 1.183
FOXE1 forkhead box E1 1.18
ALDH1A2 aldehyde dehydrogenase 1 family, member A2 1.177
GREM1 gremlin 1, DAN family BMP antagonist 1.175
TMEM11 transmembrane protein 11 1.174
SOX2 SRY (sex determining region Y)-box 2 1.174
EFNA5 ephrin-A5 1.174
EXTL3 exostosin-like glycosyltransferase 3 1.171
LHX8 LIM homeobox 8 1.17
H3-3B H3.3 histone B 1.167
KLB klotho beta 1.166
CC2D2A coiled-coil and C2 domain containing 2A 1.165
SRC SRC proto-oncogene, non-receptor tyrosine kinase 1.165
CREBBP CREB binding protein 1.165
FGF11 fibroblast growth factor 11 1.163
ETV4 ets variant 4 1.16
POLR1A polymerase (RNA) I polypeptide A, 194kDa 1.16
IFT81 intraflagellar transport 81 1.159
PPP3CA protein phosphatase 3, catalytic subunit, alpha isozyme 1.158
AP3S2 adaptor-related protein complex 3, sigma 2 subunit 1.156
MECP2 methyl CpG binding protein 2 1.155
EFNA3 ephrin-A3 1.155
CTCF CCCTC-binding factor (zinc finger protein) 1.155
PDGFRB platelet-derived growth factor receptor, beta polypeptide 1.155
CDON cell adhesion associated, oncogene regulated 1.153
EPHB2 EPH receptor B2 1.153
AZIN1 antizyme inhibitor 1 1.152
IL6R interleukin 6 receptor 1.147
TNFRSF11A tumor necrosis factor receptor superfamily, member 11a, NFKB activator 1.147
ANOS1 anosmin 1 1.145
B4GALT7 xylosylprotein beta 1,4-galactosyltransferase, polypeptide 7 1.145
FOXG1 forkhead box G1 1.144
TM4SF20 transmembrane 4 L six family member 20 1.143
FRZB frizzled-related protein 1.142
NOTCH1 notch 1 1.14
CNTLN centlein, centrosomal protein 1.136
MMP21 matrix metallopeptidase 21 1.134
FGF19 fibroblast growth factor 19 1.134
ARSB arylsulfatase B 1.133
SHROOM3 shroom family member 3 1.133
BBS1 Bardet-Biedl syndrome 1 1.133
ESCO2 establishment of sister chromatid cohesion N-acetyltransferase 2 1.132
PCNT pericentrin 1.132
WNT10A wingless-type MMTV integration site family, member 10A 1.131
LZTR1 leucine-zipper-like transcription regulator 1 1.129
IGF2 insulin-like growth factor 2 1.128
H3-4 H3.4 histone, cluster member 1.127
TGFBR3 transforming growth factor, beta receptor III 1.125
BBIP1 BBSome interacting protein 1 1.124
STAT1 signal transducer and activator of transcription 1, 91kDa 1.12
H3-5 H3.5 histone 1.119
H3C13 H3 clustered histone 13 1.119
MEF2C myocyte enhancer factor 2C 1.119
LOX lysyl oxidase 1.117
MYO7A myosin VIIA 1.117
IRX1 iroquois homeobox 1 1.117
H3C12 H3 clustered histone 12 1.116
IFT27 intraflagellar transport 27 1.116
SNAI2 snail family zinc finger 2 1.115
DCN decorin 1.114
CD200 CD200 molecule 1.113
JUN jun proto-oncogene 1.112
TBX22 T-box 22 1.111
CCDC160 coiled-coil domain containing 160 1.111
PAX7 paired box 7 1.111
MAP2K2 mitogen-activated protein kinase kinase 2 1.111
CHD8 chromodomain helicase DNA binding protein 8 1.111
GLIS3 GLIS family zinc finger 3 1.109
BMPER BMP binding endothelial regulator 1.109
TMEM145 transmembrane protein 145 1.109
GAGE12E G antigen 12E 1.109
PTGES3L-AARSD1 PTGES3L-AARSD1 readthrough 1.108
BBS2 Bardet-Biedl syndrome 2 1.108
SH3BP4 SH3-domain binding protein 4 1.106
AMZ1 archaelysin family metallopeptidase 1 1.106
NES nestin 1.105
PRR32 proline rich 32 1.105
SNAI1 snail family zinc finger 1 1.104
FAM111A family with sequence similarity 111, member A 1.103
TMEM67 transmembrane protein 67 1.103
SOS2 son of sevenless homolog 2 (Drosophila) 1.102
CYP2R1 cytochrome P450, family 2, subfamily R, polypeptide 1 1.102
ZBTB18 zinc finger and BTB domain containing 18 1.102
PTCH2 patched 2 1.101
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit 1.101
OMD osteomodulin 1.1
BRWD3 bromodomain and WD repeat domain containing 3 1.099
IGFBP3 insulin-like growth factor binding protein 3 1.099
DSPP dentin sialophosphoprotein 1.099
EFNA1 ephrin-A1 1.098
LIFR leukemia inhibitory factor receptor alpha 1.097
TMEM216 transmembrane protein 216 1.096
PRR19 proline rich 19 1.096
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase 1.096
ENG endoglin 1.096
GBX2 gastrulation brain homeobox 2 1.096
DVL2 dishevelled segment polarity protein 2 1.095
ALDH1A3 aldehyde dehydrogenase 1 family, member A3 1.092
EYA1 EYA transcriptional coactivator and phosphatase 1 1.092
AARSD1 alanyl-tRNA synthetase domain containing 1 1.092
MTOR mechanistic target of rapamycin (serine/threonine kinase) 1.089
CD44 CD44 molecule (Indian blood group) 1.089
RAB39B RAB39B, member RAS oncogene family 1.089
PKD1 polycystic kidney disease 1 (autosomal dominant) 1.088
HSD3B1 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 1.088
PKD2 polycystic kidney disease 2 (autosomal dominant) 1.087
CACNA1E calcium channel, voltage-dependent, R type, alpha 1E subunit 1.086
DLX4 distal-less homeobox 4 1.084
GDF3 growth differentiation factor 3 1.084
PAPSS2 3'-phosphoadenosine 5'-phosphosulfate synthase 2 1.083
EFEMP2 EGF containing fibulin-like extracellular matrix protein 2 1.083
MED12 mediator complex subunit 12 1.082
DHCR24 24-dehydrocholesterol reductase 1.081
GNRH1 gonadotropin-releasing hormone 1 (luteinizing-releasing hormone) 1.079
MED13L mediator complex subunit 13-like 1.078
EGFR epidermal growth factor receptor 1.078
GDF7 growth differentiation factor 7 1.076
CCN2 cellular communication network factor 2 1.076
FMOD fibromodulin 1.074
CDH17 cadherin 17, LI cadherin (liver-intestine) 1.074
NR5A1 nuclear receptor subfamily 5, group A, member 1 1.071
TULP4 tubby like protein 4 1.067
HNRNPK heterogeneous nuclear ribonucleoprotein K 1.066
ACVR2A activin A receptor, type IIA 1.065
MYOD1 myogenic differentiation 1 1.065
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2) 1.065
FLNB filamin B, beta 1.063
ARL13B ADP-ribosylation factor-like 13B 1.063
NFATC1 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1 1.061
MKS1 Meckel syndrome, type 1 1.061
CDT1 chromatin licensing and DNA replication factor 1 1.06
BRAF B-Raf proto-oncogene, serine/threonine kinase 1.059
TCTN2 tectonic family member 2 1.059
OTX2 orthodenticle homeobox 2 1.058
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 1.058
BBS4 Bardet-Biedl syndrome 4 1.058
TYK2 tyrosine kinase 2 1.057
CELSR1 cadherin, EGF LAG seven-pass G-type receptor 1 1.055
STARD8 StAR-related lipid transfer (START) domain containing 8 1.055
CYP2C19 cytochrome P450, family 2, subfamily C, polypeptide 19 1.055
ADAMTSL2 ADAMTS-like 2 1.055
MYLK myosin light chain kinase 1.054
ZEB2 zinc finger E-box binding homeobox 2 1.054
SOX3 SRY (sex determining region Y)-box 3 1.054
FOXD3 forkhead box D3 1.053
MBTPS1 membrane-bound transcription factor peptidase, site 1 1.052
IL1B interleukin 1, beta 1.051
PCDH11X protocadherin 11 X-linked 1.051
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3 1.051
PXDN peroxidasin 1.051
MYH3 myosin, heavy chain 3, skeletal muscle, embryonic 1.049
PRKACG protein kinase, cAMP-dependent, catalytic, gamma 1.048
PIEZO1 piezo-type mechanosensitive ion channel component 1 1.047
MEIS2 Meis homeobox 2 1.046
TRPS1 trichorhinophalangeal syndrome I 1.043
PRKACA protein kinase, cAMP-dependent, catalytic, alpha 1.042
GNPTAB N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits 1.042
DAND5 DAN domain family member 5, BMP antagonist 1.041
POTEF POTE ankyrin domain family, member F 1.041
COL11A2 collagen, type XI, alpha 2 1.041
GATA4 GATA binding protein 4 1.041
SFRP2 secreted frizzled-related protein 2 1.04
MYC v-myc avian myelocytomatosis viral oncogene homolog 1.04
BMPR2 bone morphogenetic protein receptor, type II (serine/threonine kinase) 1.039
PXDNL peroxidasin-like 1.039
CDC6 cell division cycle 6 1.039
ETS2 v-ets avian erythroblastosis virus E26 oncogene homolog 2 1.039
PRKACB protein kinase, cAMP-dependent, catalytic, beta 1.038
ARHGAP29 Rho GTPase activating protein 29 1.038
MCPH1 microcephalin 1 1.038
ASPM asp (abnormal spindle) homolog, microcephaly associated (Drosophila) 1.037
DNAH8 dynein, axonemal, heavy chain 8 1.035
HEATR5A HEAT repeat containing 5A 1.034
PCNA proliferating cell nuclear antigen 1.033
HHIP hedgehog interacting protein 1.032
SMOC2 SPARC related modular calcium binding 2 1.032
CYP24A1 cytochrome P450, family 24, subfamily A, polypeptide 1 1.031
PRKAR1A protein kinase, cAMP-dependent, regulatory, type I, alpha 1.028
F2 coagulation factor II (thrombin) 1.028
CPXM2 carboxypeptidase X (M14 family), member 2 1.026
GJA1 gap junction protein, alpha 1, 43kDa 1.025
OCRL oculocerebrorenal syndrome of Lowe 1.025
CRKL v-crk avian sarcoma virus CT10 oncogene homolog-like 1.025
FOXF1 forkhead box F1 1.022
PRKG2 protein kinase, cGMP-dependent, type II 1.022
PAX2 paired box 2 1.021
TK1 thymidine kinase 1, soluble 1.02
RPGRIP1L RPGRIP1-like 1.02
DISP1 dispatched homolog 1 (Drosophila) 1.018
TBX4 T-box 4 1.017
DYNC2LI1 dynein, cytoplasmic 2, light intermediate chain 1 1.017
SNAP29 synaptosomal-associated protein, 29kDa 1.016
ACVR2B activin A receptor, type IIB 1.016
GINS1 GINS complex subunit 1 (Psf1 homolog) 1.015
SFRP1 secreted frizzled-related protein 1 1.014
PROKR2 prokineticin receptor 2 1.014
CSF1 colony stimulating factor 1 (macrophage) 1.013
CHSY3 chondroitin sulfate synthase 3 1.013
SMIM23 small integral membrane protein 23 1.012
SOX8 SRY (sex determining region Y)-box 8 1.011
GP1BB glycoprotein Ib (platelet), beta polypeptide 1.011
PIGO phosphatidylinositol glycan anchor biosynthesis, class O 1.011
SMCHD1 structural maintenance of chromosomes flexible hinge domain containing 1 1.011
HOXA11 homeobox A11 1.007
MCM5 minichromosome maintenance complex component 5 1.007
FANCC Fanconi anemia, complementation group C 1.007
DVL3 dishevelled segment polarity protein 3 1.006
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) 1.003
FANCL Fanconi anemia, complementation group L 1.003
TGFA transforming growth factor, alpha 1.001
PQBP1 polyglutamine binding protein 1 1.0