| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Crizotinib (hydrochloride) perturbation in C-33 A cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Crizotinib (hydrochloride)_C-33 A drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.102802 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0598664 |
| SEMA3D | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D | 0.0565695 |
| LDHA | lactate dehydrogenase A | 0.0505209 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0487523 |
| JMJD1C | jumonji domain containing 1C | 0.0446929 |
| DST | dystonin | 0.0438331 |
| ZNF608 | zinc finger protein 608 | 0.0428244 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0411676 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0406827 |
| SHROOM3 | shroom family member 3 | 0.0401393 |
| RPS4X | ribosomal protein S4, X-linked | 0.0401122 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | 0.0368717 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0336068 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0323654 |
| MAP3K14 | mitogen-activated protein kinase kinase kinase 14 | 0.031693 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0316084 |
| CABIN1 | calcineurin binding protein 1 | 0.0315396 |
| RTN4 | reticulon 4 | 0.0300513 |
| DHFR | dihydrofolate reductase | 0.029374 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.0292191 |
| NFIA | nuclear factor I/A | 0.0290841 |
| COL5A2 | collagen, type V, alpha 2 | 0.0285524 |
| GRID2 | glutamate receptor, ionotropic, delta 2 | 0.0285181 |
| PHLPP1 | PH domain and leucine rich repeat protein phosphatase 1 | 0.0283504 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0282348 |
| VCL | vinculin | 0.028156 |
| PHF21A | PHD finger protein 21A | 0.0278628 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0277599 |
| ALDH7A1 | aldehyde dehydrogenase 7 family, member A1 | 0.027127 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0269127 |
| TBC1D9B | TBC1 domain family, member 9B (with GRAM domain) | 0.0266952 |
| PGK1 | phosphoglycerate kinase 1 | 0.0264208 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0261882 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.0259228 |
| SRSF4 | serine/arginine-rich splicing factor 4 | 0.0259028 |
| SNCA | synuclein, alpha (non A4 component of amyloid precursor) | 0.0258972 |
| EFNA5 | ephrin-A5 | 0.0258472 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0255379 |
| RPL4 | ribosomal protein L4 | 0.0251327 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.0249501 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0247889 |
| DIDO1 | death inducer-obliterator 1 | 0.0246962 |
| ATP11A | ATPase, class VI, type 11A | 0.0242726 |
| ARID2 | AT rich interactive domain 2 (ARID, RFX-like) | 0.0241139 |
| MAGEA4 | melanoma antigen family A4 | 0.0239741 |
| WDR1 | WD repeat domain 1 | 0.02396 |
| ATRN | attractin | 0.0235774 |
| SEPTIN7 | septin 7 | 0.0235509 |
| TMEM41B | transmembrane protein 41B | 0.0234466 |
| EGR1 | early growth response 1 | 0.0234219 |
| DDX3X | DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked | 0.023289 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0232442 |
| HHIP | hedgehog interacting protein | 0.0229811 |
| HNRNPUL2 | heterogeneous nuclear ribonucleoprotein U-like 2 | 0.022895 |
| LPIN2 | lipin 2 | 0.0227629 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0226307 |
| UBC | ubiquitin C | 0.0225879 |
| HNRNPR | heterogeneous nuclear ribonucleoprotein R | 0.0224556 |
| KIAA1958 | KIAA1958 | 0.0224257 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | 0.0222982 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | 0.0220517 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.022041 |
| YES1 | YES proto-oncogene 1, Src family tyrosine kinase | 0.0218929 |
| NUP58 | nucleoporin 58 | 0.0216601 |
| HELZ | helicase with zinc finger | 0.0212938 |
| ARB2A | ARB2 cotranscriptional regulator A | 0.0209343 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | 0.0205945 |
| XPO1 | exportin 1 | 0.0205575 |
| PTCH1 | patched 1 | 0.0201054 |
| ACLY | ATP citrate lyase | 0.02008 |
| SMYD3 | SET and MYND domain containing 3 | 0.0200643 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0200369 |
| RNF145 | ring finger protein 145 | 0.0199278 |
| RPL3 | ribosomal protein L3 | 0.0196946 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0195183 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.0195101 |
| MAN1A2 | mannosidase, alpha, class 1A, member 2 | 0.019486 |
| MIMS1 | mitochondrial inner membrane scaffold 1 | 0.0192988 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0192047 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0190677 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0188508 |
| MAP1B | microtubule-associated protein 1B | 0.0185886 |
| ZFAND6 | zinc finger, AN1-type domain 6 | 0.0184668 |
| MKI67 | marker of proliferation Ki-67 | 0.0184587 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0181413 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0180418 |
| ADAR | adenosine deaminase, RNA-specific | 0.0180278 |
| FADS2 | fatty acid desaturase 2 | 0.0179593 |
| RNF130 | ring finger protein 130 | 0.0179309 |
| ZNF544 | zinc finger protein 544 | 0.0178178 |
| TAC4 | tachykinin 4 (hemokinin) | 0.0176486 |
| MATR3 | matrin 3 | 0.0176052 |
| CNN2 | calponin 2 | 0.0175346 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0174935 |
| RPL13A | ribosomal protein L13a | 0.0172475 |
| GYS1 | glycogen synthase 1 (muscle) | 0.017109 |
| NR2F1 | nuclear receptor subfamily 2, group F, member 1 | 0.0170957 |
| ELF2 | E74-like factor 2 (ets domain transcription factor) | 0.0170321 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0169731 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CTNNA2 | catenin (cadherin-associated protein), alpha 2 | -0.166772 |
| ERBB4 | erb-b2 receptor tyrosine kinase 4 | -0.139004 |
| TENM3 | teneurin transmembrane protein 3 | -0.138755 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.115287 |
| CTNNA3 | catenin (cadherin-associated protein), alpha 3 | -0.0937635 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0901732 |
| NEBL | nebulette | -0.0836338 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0588124 |
| ARHGAP32 | Rho GTPase activating protein 32 | -0.0587279 |
| SLIT2 | slit homolog 2 (Drosophila) | -0.0583736 |
| BACH2 | BTB and CNC homology 1, basic leucine zipper transcription factor 2 | -0.0543485 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0505415 |
| PTMA | prothymosin, alpha | -0.0494547 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0476109 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0458444 |
| TMSB10 | thymosin beta 10 | -0.0416649 |
| CELF2 | CUGBP, Elav-like family member 2 | -0.0388658 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.0358505 |
| CCSER1 | coiled-coil serine-rich protein 1 | -0.0357742 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0342828 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | -0.0326099 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.032474 |
| RCC1 | regulator of chromosome condensation 1 | -0.0301711 |
| MAP4 | microtubule-associated protein 4 | -0.0299724 |
| HMGB1 | high mobility group box 1 | -0.0297627 |
| DENND1A | DENN/MADD domain containing 1A | -0.0294099 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0293936 |
| EXOC4 | exocyst complex component 4 | -0.028573 |
| HMGA1 | high mobility group AT-hook 1 | -0.0268538 |
| SERBP1 | SERPINE1 mRNA binding protein 1 | -0.0238465 |
| ACTG1 | actin gamma 1 | -0.023719 |
| EIF5B | eukaryotic translation initiation factor 5B | -0.0232711 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0232641 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0231707 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0231021 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0226734 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0226096 |
| EMP1 | epithelial membrane protein 1 | -0.0221562 |
| SALL4 | spalt-like transcription factor 4 | -0.0214235 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0213753 |
| UBAP2 | ubiquitin associated protein 2 | -0.0213112 |
| BCAS3 | breast carcinoma amplified sequence 3 | -0.0205185 |
| WWOX | WW domain containing oxidoreductase | -0.0202843 |
| PRH1 | proline-rich protein HaeIII subfamily 1 | -0.0202446 |
| JUN | jun proto-oncogene | -0.0196997 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0192674 |
| MLIP | muscular LMNA-interacting protein | -0.0191121 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | -0.0190518 |
| SF3B2 | splicing factor 3b, subunit 2, 145kDa | -0.0190045 |
| ANKRD17 | ankyrin repeat domain 17 | -0.0188336 |
| PHF3 | PHD finger protein 3 | -0.0187598 |
| HNRNPM | heterogeneous nuclear ribonucleoprotein M | -0.0185842 |
| NF1 | neurofibromin 1 | -0.0185045 |
| TTC17 | tetratricopeptide repeat domain 17 | -0.0181972 |
| RIGI | RNA sensor RIG-I | -0.0181881 |
| BPTF | bromodomain PHD finger transcription factor | -0.018075 |
| ANXA2 | annexin A2 | -0.0180453 |
| TRMT11 | tRNA methyltransferase 11 homolog (S. cerevisiae) | -0.0179857 |
| NR6A1 | nuclear receptor subfamily 6, group A, member 1 | -0.0178404 |
| NAP1L4 | nucleosome assembly protein 1-like 4 | -0.0175812 |
| LYST | lysosomal trafficking regulator | -0.0173379 |
| RPL12 | ribosomal protein L12 | -0.0171366 |
| FTL | ferritin, light polypeptide | -0.0171029 |
| ZRANB3 | zinc finger, RAN-binding domain containing 3 | -0.017074 |
| NEDD4 | neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase | -0.0170267 |
| MSH4 | mutS homolog 4 | -0.0168345 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | -0.0167571 |
| RBM25 | RNA binding motif protein 25 | -0.0165833 |
| PNPT1 | polyribonucleotide nucleotidyltransferase 1 | -0.016488 |
| MIPOL1 | mirror-image polydactyly 1 | -0.0164098 |
| THOC2 | THO complex 2 | -0.0163983 |
| RNF213 | ring finger protein 213 | -0.0163514 |
| EHBP1 | EH domain binding protein 1 | -0.0162697 |
| TBC1D5 | TBC1 domain family, member 5 | -0.0160364 |
| RANBP17 | RAN binding protein 17 | -0.0157495 |
| RPS25 | ribosomal protein S25 | -0.0157485 |
| TBC1D32 | TBC1 domain family, member 32 | -0.0157425 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | -0.0157294 |
| PFN1 | profilin 1 | -0.0155638 |
| HELLS | helicase, lymphoid-specific | -0.0155518 |
| SYNE1 | spectrin repeat containing, nuclear envelope 1 | -0.0154328 |
| ANKRD1 | ankyrin repeat domain 1 (cardiac muscle) | -0.0153861 |
| PARD3 | par-3 family cell polarity regulator | -0.0153457 |
| RPL18 | ribosomal protein L18 | -0.0151758 |
| VIM | vimentin | -0.0151593 |
| BDP1 | B double prime 1, subunit of RNA polymerase III transcription initiation factor IIIB | -0.0151292 |
| STC1 | stanniocalcin 1 | -0.0148553 |
| AEBP2 | AE binding protein 2 | -0.0148253 |
| CDH18 | cadherin 18, type 2 | -0.0148124 |
| SUPT16H | suppressor of Ty 16 homolog (S. cerevisiae) | -0.014713 |
| ID3 | inhibitor of DNA binding 3, dominant negative helix-loop-helix protein | -0.014681 |
| PKP4 | plakophilin 4 | -0.0146803 |
| PTK2 | protein tyrosine kinase 2 | -0.0146754 |
| PA2G4 | proliferation-associated 2G4, 38kDa | -0.0146493 |
| LARS1 | leucyl-tRNA synthetase 1 | -0.0146255 |
| KLF6 | Kruppel-like factor 6 | -0.0145626 |
| RPL37A | ribosomal protein L37a | -0.014469 |
| WDR27 | WD repeat domain 27 | -0.0144354 |
| SHPRH | SNF2 histone linker PHD RING helicase, E3 ubiquitin protein ligase | -0.0142935 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | -0.0142024 |
