| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Crizotinib (hydrochloride) perturbation in C32 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Crizotinib (hydrochloride)_C32 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | 0.132731 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0573664 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0467632 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0457049 |
| NAV2 | neuron navigator 2 | 0.0416727 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0415892 |
| COPA | coatomer protein complex, subunit alpha | 0.0352496 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0331828 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0327133 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0316248 |
| VGF | VGF nerve growth factor inducible | 0.0312141 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0286717 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0286653 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0277392 |
| CABIN1 | calcineurin binding protein 1 | 0.0270582 |
| FLNA | filamin A, alpha | 0.0266031 |
| MT2A | metallothionein 2A | 0.0265888 |
| APP | amyloid beta (A4) precursor protein | 0.026269 |
| VEGFA | vascular endothelial growth factor A | 0.0259858 |
| NUP58 | nucleoporin 58 | 0.0254683 |
| TAC4 | tachykinin 4 (hemokinin) | 0.0253618 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0252309 |
| RNF145 | ring finger protein 145 | 0.02517 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.024577 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | 0.0239703 |
| FYN | FYN proto-oncogene, Src family tyrosine kinase | 0.0238629 |
| PTMA | prothymosin, alpha | 0.0231536 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0227415 |
| INSIG1 | insulin induced gene 1 | 0.0226815 |
| GDF15 | growth differentiation factor 15 | 0.0226466 |
| CDC73 | cell division cycle 73 | 0.021904 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0212847 |
| ICAM1 | intercellular adhesion molecule 1 | 0.0204865 |
| SMAD3 | SMAD family member 3 | 0.0201567 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0199492 |
| HELZ | helicase with zinc finger | 0.019741 |
| WDR43 | WD repeat domain 43 | 0.0196373 |
| ADM | adrenomedullin | 0.0194913 |
| SETD5 | SET domain containing 5 | 0.0194497 |
| CALR | calreticulin | 0.0192213 |
| MIDEAS | mitotic deacetylase associated SANT domain protein | 0.018832 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0187861 |
| ARRDC3 | arrestin domain containing 3 | 0.0186562 |
| RYBP | RING1 and YY1 binding protein | 0.0184918 |
| RGS2 | regulator of G-protein signaling 2 | 0.0184606 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0184526 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0183437 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0180428 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.017819 |
| DDX3Y | DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked | 0.0176477 |
| MATR3 | matrin 3 | 0.0175882 |
| CD109 | CD109 molecule | 0.0174277 |
| BRD2 | bromodomain containing 2 | 0.017367 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0172715 |
| PACSIN2 | protein kinase C and casein kinase substrate in neurons 2 | 0.0171615 |
| MRTFA | myocardin related transcription factor A | 0.0166864 |
| HNRNPM | heterogeneous nuclear ribonucleoprotein M | 0.016677 |
| PRPF8 | pre-mRNA processing factor 8 | 0.0166328 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0163992 |
| SF3B2 | splicing factor 3b, subunit 2, 145kDa | 0.0163103 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0162748 |
| IFRD1 | interferon-related developmental regulator 1 | 0.0162422 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0161592 |
| CCNL1 | cyclin L1 | 0.0161457 |
| TRA2B | transformer 2 beta homolog (Drosophila) | 0.0161127 |
| UBC | ubiquitin C | 0.0159819 |
| SSBP3 | single stranded DNA binding protein 3 | 0.0159587 |
| LMNA | lamin A/C | 0.0158688 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | 0.0155922 |
| RPS3 | ribosomal protein S3 | 0.015454 |
| SLC4A2 | solute carrier family 4 (anion exchanger), member 2 | 0.0154283 |
| UBA2 | ubiquitin-like modifier activating enzyme 2 | 0.0154264 |
| SND1 | staphylococcal nuclease and tudor domain containing 1 | 0.0154065 |
| RBM33 | RNA binding motif protein 33 | 0.015345 |
| CUL3 | cullin 3 | 0.0152814 |
| CENPF | centromere protein F, 350/400kDa | 0.0152229 |
| RPL11 | ribosomal protein L11 | 0.0152128 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.0149848 |
| KIRREL1 | kirre like nephrin family adhesion molecule 1 | 0.0149756 |
| FLNB | filamin B, beta | 0.0148794 |
| ACTN4 | actinin, alpha 4 | 0.0148371 |
| PCBP2 | poly(rC) binding protein 2 | 0.0147413 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | 0.0145184 |
| FOSL1 | FOS-like antigen 1 | 0.0144086 |
| HMGB2 | high mobility group box 2 | 0.0144005 |
| MKRN1 | makorin ring finger protein 1 | 0.0143433 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0142788 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0142052 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0141579 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 0.0140885 |
| CALU | calumenin | 0.0140283 |
| RPL3 | ribosomal protein L3 | 0.0140262 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0139444 |
| IRS2 | insulin receptor substrate 2 | 0.0138341 |
| RPS12 | ribosomal protein S12 | 0.0136283 |
| RPL7 | ribosomal protein L7 | 0.0135756 |
| DDX6 | DEAD (Asp-Glu-Ala-Asp) box helicase 6 | 0.0135396 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.0135089 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | 0.013479 |
| SRRT | serrate, RNA effector molecule | 0.0134194 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.279371 |
| GPC6 | glypican 6 | -0.269538 |
| FN1 | fibronectin 1 | -0.23952 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | -0.19408 |
| NLGN1 | neuroligin 1 | -0.126569 |
| MDGA2 | MAM domain containing glycosylphosphatidylinositol anchor 2 | -0.113007 |
| FMN1 | formin 1 | -0.112059 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0976657 |
| FRMD4A | FERM domain containing 4A | -0.0938587 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0893553 |
| COL19A1 | collagen, type XIX, alpha 1 | -0.0832454 |
| EHBP1 | EH domain binding protein 1 | -0.0747625 |
| MACROD2 | MACRO domain containing 2 | -0.0738887 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0708231 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0702498 |
| RUNX1 | runt-related transcription factor 1 | -0.0689852 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | -0.0666809 |
| EXOC4 | exocyst complex component 4 | -0.0664124 |
| OXR1 | oxidation resistance 1 | -0.0650636 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | -0.0640391 |
| IGFBP5 | insulin-like growth factor binding protein 5 | -0.0618924 |
| TNNC1 | troponin C type 1 (slow) | -0.0610552 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0544001 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0542981 |
| NAV3 | neuron navigator 3 | -0.0518544 |
| LRMDA | leucine rich melanocyte differentiation associated | -0.0510713 |
| PRELID2 | PRELI domain containing 2 | -0.0493859 |
| DST | dystonin | -0.0485214 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | -0.0481063 |
| HMCN1 | hemicentin 1 | -0.0478905 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0476391 |
| NPC1 | Niemann-Pick disease, type C1 | -0.0450199 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | -0.0438527 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0428326 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.0425036 |
| SOX5 | SRY (sex determining region Y)-box 5 | -0.0412572 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0410767 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0393934 |
| MMP16 | matrix metallopeptidase 16 (membrane-inserted) | -0.0385876 |
| CDK14 | cyclin-dependent kinase 14 | -0.038154 |
| SCFD2 | sec1 family domain containing 2 | -0.0379444 |
| RAD51B | RAD51 paralog B | -0.0371131 |
| PCDH7 | protocadherin 7 | -0.0371012 |
| NBEA | neurobeachin | -0.0356376 |
| PRKD1 | protein kinase D1 | -0.0353175 |
| LINGO2 | leucine rich repeat and Ig domain containing 2 | -0.0347412 |
| CPED1 | cadherin-like and PC-esterase domain containing 1 | -0.0345522 |
| PDE10A | phosphodiesterase 10A | -0.0341908 |
| ASPH | aspartate beta-hydroxylase | -0.034167 |
| OSMR | oncostatin M receptor | -0.033467 |
| ITGB8 | integrin, beta 8 | -0.0323177 |
| ACTG1 | actin gamma 1 | -0.0316468 |
| EGR1 | early growth response 1 | -0.0315986 |
| SMYD3 | SET and MYND domain containing 3 | -0.0315431 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0314139 |
| NRCAM | neuronal cell adhesion molecule | -0.0312579 |
| ST6GALNAC3 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3 | -0.0310411 |
| TNFRSF19 | tumor necrosis factor receptor superfamily, member 19 | -0.030814 |
| LEF1 | lymphoid enhancer-binding factor 1 | -0.0305811 |
| C10ORF90 | chromosome 10 open reading frame 90 | -0.0303793 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0302706 |
| SETBP1 | SET binding protein 1 | -0.0302675 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) | -0.0299218 |
| FBXL17 | F-box and leucine-rich repeat protein 17 | -0.0295218 |
| FRMD5 | FERM domain containing 5 | -0.0290973 |
| GHR | growth hormone receptor | -0.0287412 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0287082 |
| BABAM2 | BRISC and BRCA1 A complex member 2 | -0.0281835 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | -0.0280559 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | -0.027553 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0275328 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.02733 |
| PHC2 | polyhomeotic homolog 2 (Drosophila) | -0.0264904 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0264613 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | -0.0262681 |
| LRAT | lecithin retinol acyltransferase (phosphatidylcholine--retinol O-acyltransferase) | -0.0257427 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0255673 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0255504 |
| MITF | microphthalmia-associated transcription factor | -0.0255072 |
| FHIT | fragile histidine triad | -0.0254883 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0254674 |
| NEGR1 | neuronal growth regulator 1 | -0.0250567 |
| TBC1D22A | TBC1 domain family, member 22A | -0.025029 |
| AHCYL2 | adenosylhomocysteinase-like 2 | -0.0249324 |
| SHROOM4 | shroom family member 4 | -0.0247401 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.0247179 |
| ANKRD28 | ankyrin repeat domain 28 | -0.024476 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | -0.0244385 |
| ANK2 | ankyrin 2, neuronal | -0.0244151 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0242947 |
| PLA2G4A | phospholipase A2, group IVA (cytosolic, calcium-dependent) | -0.0241515 |
| CTTNBP2 | cortactin binding protein 2 | -0.0241221 |
| RANBP17 | RAN binding protein 17 | -0.023547 |
| NAALADL2 | N-acetylated alpha-linked acidic dipeptidase-like 2 | -0.0235154 |
| PTPRD | protein tyrosine phosphatase, receptor type, D | -0.0235137 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.023386 |
| NHSL1 | NHS-like 1 | -0.023356 |
| ATXN7L1 | ataxin 7-like 1 | -0.0231374 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 | -0.023126 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | -0.0231162 |
