| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Crizotinib (hydrochloride) perturbation in CFPAC-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Crizotinib (hydrochloride)_CFPAC-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.120333 |
| VIM | vimentin | 0.111276 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.100926 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0895162 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0868141 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0807922 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0765409 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0716719 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0698633 |
| FLNA | filamin A, alpha | 0.0534485 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0483394 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0481402 |
| SPAG9 | sperm associated antigen 9 | 0.047563 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0473864 |
| KRT18 | keratin 18, type I | 0.044582 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0434278 |
| VEGFA | vascular endothelial growth factor A | 0.0429707 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0402149 |
| EZR | ezrin | 0.0401086 |
| CCNY | cyclin Y | 0.0379511 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.037523 |
| CALR | calreticulin | 0.0359515 |
| FAM13A | family with sequence similarity 13, member A | 0.035819 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0341765 |
| CANX | calnexin | 0.0339659 |
| G0S2 | G0/G1 switch 2 | 0.0333884 |
| FLNB | filamin B, beta | 0.0327028 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0325884 |
| ATF4 | activating transcription factor 4 | 0.0323419 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0308326 |
| YTHDC1 | YTH domain containing 1 | 0.0305854 |
| TMSB4X | thymosin beta 4, X-linked | 0.030369 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0296462 |
| CIB1 | calcium and integrin binding 1 (calmyrin) | 0.0281673 |
| APP | amyloid beta (A4) precursor protein | 0.0277649 |
| NUP58 | nucleoporin 58 | 0.0274628 |
| ARRDC3 | arrestin domain containing 3 | 0.0273285 |
| CASC3 | cancer susceptibility candidate 3 | 0.0271213 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0265169 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0262798 |
| MATR3 | matrin 3 | 0.0261409 |
| USP3 | ubiquitin specific peptidase 3 | 0.025411 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0253862 |
| MEF2A | myocyte enhancer factor 2A | 0.0248616 |
| RAP2B | RAP2B, member of RAS oncogene family | 0.0245861 |
| PCBP2 | poly(rC) binding protein 2 | 0.024527 |
| DIAPH1 | diaphanous-related formin 1 | 0.0243863 |
| PLAU | plasminogen activator, urokinase | 0.0243396 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | 0.024317 |
| YME1L1 | YME1-like 1 ATPase | 0.0241924 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0241489 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0237019 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0227812 |
| BTAF1 | BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa | 0.0225835 |
| CCNL1 | cyclin L1 | 0.0223325 |
| ANXA1 | annexin A1 | 0.0222407 |
| COPA | coatomer protein complex, subunit alpha | 0.0219805 |
| YBX1 | Y box binding protein 1 | 0.0219341 |
| TOP1 | topoisomerase (DNA) I | 0.0218219 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0217822 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0213087 |
| ACIN1 | apoptotic chromatin condensation inducer 1 | 0.0212734 |
| MYO5B | myosin VB | 0.0211936 |
| OGA | O-GlcNAcase | 0.0211857 |
| ABI1 | abl-interactor 1 | 0.0210331 |
| FNBP1L | formin binding protein 1-like | 0.0207676 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0205827 |
| RPL4 | ribosomal protein L4 | 0.0205392 |
| RAB8B | RAB8B, member RAS oncogene family | 0.0199091 |
| BRD2 | bromodomain containing 2 | 0.0198521 |
| RPS4X | ribosomal protein S4, X-linked | 0.0197353 |
| PNN | pinin, desmosome associated protein | 0.019701 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | 0.0196151 |
| RNF149 | ring finger protein 149 | 0.0195618 |
| PDIA4 | protein disulfide isomerase family A, member 4 | 0.0194598 |
| MYO1B | myosin IB | 0.0194187 |
| ACTN4 | actinin, alpha 4 | 0.0185515 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0184275 |
| RIOK3 | RIO kinase 3 | 0.0181389 |
| KLF6 | Kruppel-like factor 6 | 0.0181256 |
| IRF6 | interferon regulatory factor 6 | 0.0180678 |
| KIRREL1 | kirre like nephrin family adhesion molecule 1 | 0.0180378 |
| ARHGEF2 | Rho/Rac guanine nucleotide exchange factor (GEF) 2 | 0.0180265 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0178048 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0174651 |
| NPTN | neuroplastin | 0.0173669 |
| HDGF | hepatoma-derived growth factor | 0.0171356 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0168957 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0168689 |
| SMG7 | SMG7 nonsense mediated mRNA decay factor | 0.0168276 |
| SUPT5H | suppressor of Ty 5 homolog (S. cerevisiae) | 0.0168245 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.016734 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0167144 |
| IRS2 | insulin receptor substrate 2 | 0.0166017 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.016422 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | 0.0162785 |
| CAPZA2 | capping protein (actin filament) muscle Z-line, alpha 2 | 0.0162238 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.0160545 |
| SPCS2 | signal peptidase complex subunit 2 homolog (S. cerevisiae) | 0.0158803 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | 0.0157274 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.246445 |
| HLA-B | major histocompatibility complex, class I, B | -0.182334 |
| CP | ceruloplasmin (ferroxidase) | -0.114229 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.112405 |
| MMP7 | matrix metallopeptidase 7 | -0.111887 |
| APOL1 | apolipoprotein L, 1 | -0.110465 |
| MT2A | metallothionein 2A | -0.0972818 |
| B2M | beta-2-microglobulin | -0.0943266 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0925717 |
| ASPH | aspartate beta-hydroxylase | -0.0886128 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0824829 |
| ACTG1 | actin gamma 1 | -0.0724677 |
| RPL35A | ribosomal protein L35a | -0.0714141 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.0698781 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.06869 |
| EFNA5 | ephrin-A5 | -0.0674308 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0623576 |
| RPL34 | ribosomal protein L34 | -0.0594615 |
| NDRG1 | N-myc downstream regulated 1 | -0.058497 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0582928 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0558481 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0555677 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0552914 |
| RPS29 | ribosomal protein S29 | -0.0546522 |
| RAD51B | RAD51 paralog B | -0.0540248 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0537424 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0528207 |
| SP100 | SP100 nuclear antigen | -0.0520764 |
| S100A10 | S100 calcium binding protein A10 | -0.0520294 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0510586 |
| RPS8 | ribosomal protein S8 | -0.0497186 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0486223 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0463711 |
| RPS24 | ribosomal protein S24 | -0.0460662 |
| CD2AP | CD2-associated protein | -0.0456651 |
| PLAT | plasminogen activator, tissue | -0.0455038 |
| MX2 | MX dynamin-like GTPase 2 | -0.0453597 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | -0.0450828 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0449478 |
| POTEF | POTE ankyrin domain family, member F | -0.044423 |
| RPS21 | ribosomal protein S21 | -0.0440237 |
| NABP1 | nucleic acid binding protein 1 | -0.0436786 |
| ENO1 | enolase 1, (alpha) | -0.0436739 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0431302 |
| RPLP1 | ribosomal protein, large, P1 | -0.0431145 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0423911 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0422836 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | -0.0420785 |
| OSMR | oncostatin M receptor | -0.0419724 |
| CSTB | cystatin B (stefin B) | -0.0418183 |
| DSG2 | desmoglein 2 | -0.0417119 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | -0.041694 |
| LCN2 | lipocalin 2 | -0.0416181 |
| EHBP1 | EH domain binding protein 1 | -0.0413883 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0410713 |
| TMSB10 | thymosin beta 10 | -0.0410174 |
| RNF213 | ring finger protein 213 | -0.0410019 |
| NT5C2 | 5'-nucleotidase, cytosolic II | -0.0404964 |
| BPTF | bromodomain PHD finger transcription factor | -0.0404001 |
| PRKCA | protein kinase C, alpha | -0.0402051 |
| PMP22 | peripheral myelin protein 22 | -0.0399925 |
| RPL37A | ribosomal protein L37a | -0.0399669 |
| DOCK5 | dedicator of cytokinesis 5 | -0.0399003 |
| TBC1D22A | TBC1 domain family, member 22A | -0.0394378 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0387755 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0386205 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0380365 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0379583 |
| RPL31 | ribosomal protein L31 | -0.0378014 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0376195 |
| NUMB | numb homolog (Drosophila) | -0.0370106 |
| PCDH7 | protocadherin 7 | -0.0369209 |
| DST | dystonin | -0.0364653 |
| S100A6 | S100 calcium binding protein A6 | -0.036324 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0362076 |
| ANXA2 | annexin A2 | -0.0362037 |
| RPL9 | ribosomal protein L9 | -0.036056 |
| SMYD3 | SET and MYND domain containing 3 | -0.035998 |
| ANXA4 | annexin A4 | -0.0358283 |
| EGR1 | early growth response 1 | -0.0355272 |
| MT1E | metallothionein 1E | -0.0350769 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | -0.0350463 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0348451 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0346471 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0345951 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0338896 |
| MUC4 | mucin 4, cell surface associated | -0.0338776 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0337692 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.033472 |
| ST8SIA6 | ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 6 | -0.0330316 |
| RIGI | RNA sensor RIG-I | -0.0328716 |
| ANKRD1 | ankyrin repeat domain 1 (cardiac muscle) | -0.0327298 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0325408 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.0322891 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0321195 |
| MX1 | MX dynamin-like GTPase 1 | -0.0319414 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | -0.0316201 |
| ATXN1 | ataxin 1 | -0.0314274 |
| RRBP1 | ribosome binding protein 1 | -0.031171 |
| C15ORF48 | chromosome 15 open reading frame 48 | -0.0310684 |
