| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Crizotinib (hydrochloride) perturbation in CHP-212 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Crizotinib (hydrochloride)_CHP-212 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.137262 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0841968 |
| VCL | vinculin | 0.081743 |
| CRH | corticotropin releasing hormone | 0.0533785 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.048673 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0477094 |
| FLNA | filamin A, alpha | 0.0465757 |
| FMN1 | formin 1 | 0.0463318 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0458901 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0428054 |
| GPC5 | glypican 5 | 0.0407583 |
| LGR5 | leucine-rich repeat containing G protein-coupled receptor 5 | 0.0407105 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0403676 |
| SEPTIN9 | septin 9 | 0.0402997 |
| SLITRK6 | SLIT and NTRK-like family, member 6 | 0.0386926 |
| VIM | vimentin | 0.0383175 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0368555 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0365371 |
| VGF | VGF nerve growth factor inducible | 0.0355918 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0353044 |
| ACLY | ATP citrate lyase | 0.0327204 |
| COL6A1 | collagen, type VI, alpha 1 | 0.0284563 |
| RSL1D1 | ribosomal L1 domain containing 1 | 0.0284047 |
| AFF4 | AF4/FMR2 family, member 4 | 0.0279852 |
| VEGFA | vascular endothelial growth factor A | 0.0276338 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0275598 |
| MAP1B | microtubule-associated protein 1B | 0.0269013 |
| RPS4X | ribosomal protein S4, X-linked | 0.0263412 |
| NUMA1 | nuclear mitotic apparatus protein 1 | 0.0253989 |
| ANGPT1 | angiopoietin 1 | 0.025268 |
| EGR1 | early growth response 1 | 0.0247712 |
| AHR | aryl hydrocarbon receptor | 0.0247236 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0244694 |
| XPR1 | xenotropic and polytropic retrovirus receptor 1 | 0.0243138 |
| CDPF1 | cysteine-rich, DPF motif domain containing 1 | 0.0241374 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.024027 |
| RPL19 | ribosomal protein L19 | 0.0235746 |
| KLF6 | Kruppel-like factor 6 | 0.0235615 |
| RGS4 | regulator of G-protein signaling 4 | 0.0235422 |
| PRPF3 | pre-mRNA processing factor 3 | 0.0234143 |
| ANK2 | ankyrin 2, neuronal | 0.0231944 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.022623 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0222709 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0222009 |
| PTPN13 | protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase) | 0.0220628 |
| TOB1 | transducer of ERBB2, 1 | 0.021906 |
| SSBP3 | single stranded DNA binding protein 3 | 0.0218665 |
| DBN1 | drebrin 1 | 0.0217082 |
| HMBOX1 | homeobox containing 1 | 0.0214867 |
| SLC2A13 | solute carrier family 2 (facilitated glucose transporter), member 13 | 0.0213603 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0211937 |
| RPL7 | ribosomal protein L7 | 0.0209554 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | 0.0205273 |
| SRP68 | signal recognition particle 68kDa | 0.0204404 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | 0.0202765 |
| SHC1 | SHC (Src homology 2 domain containing) transforming protein 1 | 0.0202756 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0200897 |
| NES | nestin | 0.0200127 |
| DKK2 | dickkopf WNT signaling pathway inhibitor 2 | 0.020011 |
| RPL4 | ribosomal protein L4 | 0.0196791 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0196434 |
| SNRNP200 | small nuclear ribonucleoprotein 200kDa (U5) | 0.0194849 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | 0.0194184 |
| ARRDC3 | arrestin domain containing 3 | 0.0193217 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | 0.019013 |
| SF3A1 | splicing factor 3a, subunit 1, 120kDa | 0.0189238 |
| FHL2 | four and a half LIM domains 2 | 0.0188909 |
| PRKAR1A | protein kinase, cAMP-dependent, regulatory, type I, alpha | 0.0187447 |
| ZBTB41 | zinc finger and BTB domain containing 41 | 0.0187369 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0187268 |
| KRT18 | keratin 18, type I | 0.0187265 |
| DCUN1D5 | DCN1, defective in cullin neddylation 1, domain containing 5 | 0.0186249 |
| CDK19 | cyclin-dependent kinase 19 | 0.0186064 |
| ADAMTS1 | ADAM metallopeptidase with thrombospondin type 1 motif, 1 | 0.018553 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.018395 |
| ACTN4 | actinin, alpha 4 | 0.018363 |
| AFDN | afadin, adherens junction formation factor | 0.0183045 |
| RAD21 | RAD21 homolog (S. pombe) | 0.0182254 |
| RGS2 | regulator of G-protein signaling 2 | 0.0181124 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | 0.0180851 |
| ATRNL1 | attractin-like 1 | 0.0180791 |
| PLAT | plasminogen activator, tissue | 0.0179986 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0179799 |
| EHD2 | EH-domain containing 2 | 0.0179622 |
| DDX3Y | DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked | 0.0175687 |
| PTGES3 | prostaglandin E synthase 3 (cytosolic) | 0.0174994 |
| SCG2 | secretogranin II | 0.0174801 |
| ATP1A4 | ATPase, Na+/K+ transporting, alpha 4 polypeptide | 0.0173963 |
| SNAP25 | synaptosomal-associated protein, 25kDa | 0.017066 |
| FAM168B | family with sequence similarity 168, member B | 0.0169764 |
| EPC2 | enhancer of polycomb homolog 2 (Drosophila) | 0.0168972 |
| RNF145 | ring finger protein 145 | 0.0167498 |
| HEY1 | hes-related family bHLH transcription factor with YRPW motif 1 | 0.0166136 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | 0.016603 |
| TMF1 | TATA element modulatory factor 1 | 0.0163706 |
| NUP98 | nucleoporin 98kDa | 0.0163328 |
| IER2 | immediate early response 2 | 0.0161909 |
| SPRED1 | sprouty-related, EVH1 domain containing 1 | 0.0161364 |
| HOMER1 | homer scaffolding protein 1 | 0.0160632 |
| ZFC3H1 | zinc finger, C3H1-type containing | 0.0159464 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IGF2 | insulin-like growth factor 2 | -0.378048 |
| DDX1 | DEAD (Asp-Glu-Ala-Asp) box helicase 1 | -0.262199 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.12362 |
| NRG1 | neuregulin 1 | -0.113106 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.110448 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0963621 |
| COL1A1 | collagen, type I, alpha 1 | -0.0861384 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0784483 |
| MEIS2 | Meis homeobox 2 | -0.0767811 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0726778 |
| CDH10 | cadherin 10, type 2 (T2-cadherin) | -0.0670285 |
| CENPF | centromere protein F, 350/400kDa | -0.0630844 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.0623592 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | -0.0590151 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.057767 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0566076 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0566013 |
| NDRG1 | N-myc downstream regulated 1 | -0.0558186 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0550978 |
| LPIN1 | lipin 1 | -0.0535613 |
| MSI2 | musashi RNA-binding protein 2 | -0.0530531 |
| NFIB | nuclear factor I/B | -0.0528414 |
| LRFN5 | leucine rich repeat and fibronectin type III domain containing 5 | -0.0508494 |
| RPS6 | ribosomal protein S6 | -0.0499223 |
| GOLGA4 | golgin A4 | -0.0492761 |
| HELZ | helicase with zinc finger | -0.0491315 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0486606 |
| ACTG1 | actin gamma 1 | -0.0482038 |
| BCAS3 | breast carcinoma amplified sequence 3 | -0.0477051 |
| COL4A5 | collagen, type IV, alpha 5 | -0.0475417 |
| ANTXR1 | anthrax toxin receptor 1 | -0.0472586 |
| B2M | beta-2-microglobulin | -0.0467428 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0467252 |
| RPL35A | ribosomal protein L35a | -0.0465512 |
| ZNF292 | zinc finger protein 292 | -0.0461821 |
| FN1 | fibronectin 1 | -0.0445692 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0443775 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0441338 |
| RPLP1 | ribosomal protein, large, P1 | -0.043941 |
| BPTF | bromodomain PHD finger transcription factor | -0.0436381 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0432761 |
| TPR | translocated promoter region, nuclear basket protein | -0.0429403 |
| CD36 | CD36 molecule (thrombospondin receptor) | -0.0424744 |
| PTEN | phosphatase and tensin homolog | -0.0423596 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0420774 |
| RPL38 | ribosomal protein L38 | -0.0418575 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0407901 |
| WDR45B | WD repeat domain 45B | -0.039405 |
| TMSB10 | thymosin beta 10 | -0.0390611 |
| FBXO11 | F-box protein 11 | -0.0384281 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | -0.0383403 |
| SMYD3 | SET and MYND domain containing 3 | -0.0379822 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.037973 |
| ZNF638 | zinc finger protein 638 | -0.0379658 |
| NRP1 | neuropilin 1 | -0.0378102 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0377337 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0377257 |
| POTEF | POTE ankyrin domain family, member F | -0.03764 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0375288 |
| RPS27A | ribosomal protein S27a | -0.0375087 |
| RBM39 | RNA binding motif protein 39 | -0.0374445 |
| MED13 | mediator complex subunit 13 | -0.0371333 |
| USP34 | ubiquitin specific peptidase 34 | -0.0368349 |
| NREP | neuronal regeneration related protein | -0.0364929 |
| RFX7 | regulatory factor X, 7 | -0.0364724 |
| MED13L | mediator complex subunit 13-like | -0.0363403 |
| SRPK2 | SRSF protein kinase 2 | -0.0362235 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0362054 |
| AHNAK | AHNAK nucleoprotein | -0.0361637 |
| PCBP2 | poly(rC) binding protein 2 | -0.0361128 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | -0.0359614 |
| EPAS1 | endothelial PAS domain protein 1 | -0.0358042 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0357391 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0349525 |
| RPTOR | regulatory associated protein of MTOR, complex 1 | -0.034804 |
| RPL34 | ribosomal protein L34 | -0.0345408 |
| ARID1B | AT rich interactive domain 1B (SWI1-like) | -0.0344491 |
| RBM25 | RNA binding motif protein 25 | -0.0342484 |
| LMAN1 | lectin, mannose-binding, 1 | -0.034105 |
| GLG1 | golgi glycoprotein 1 | -0.0335866 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0335677 |
| CCDC88A | coiled-coil domain containing 88A | -0.0333301 |
| MEF2A | myocyte enhancer factor 2A | -0.0331366 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0329332 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | -0.0327956 |
| ANKRD11 | ankyrin repeat domain 11 | -0.032784 |
| VMP1 | vacuole membrane protein 1 | -0.0326861 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.031828 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0316578 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | -0.0316239 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0312546 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | -0.0311924 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0311894 |
| BRWD1 | bromodomain and WD repeat domain containing 1 | -0.031153 |
| CHD9 | chromodomain helicase DNA binding protein 9 | -0.0309254 |
| RPL37A | ribosomal protein L37a | -0.030924 |
| ATXN2 | ataxin 2 | -0.0308625 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0307235 |
| TRIP12 | thyroid hormone receptor interactor 12 | -0.0305625 |
| HMGB2 | high mobility group box 2 | -0.0304996 |
