| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Crizotinib (hydrochloride) perturbation in H4 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Crizotinib (hydrochloride)_H4 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| COL6A3 | collagen, type VI, alpha 3 | 0.251933 |
| VIM | vimentin | 0.167723 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.143728 |
| CANX | calnexin | 0.133399 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.109787 |
| CALR | calreticulin | 0.0959042 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0858354 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0822596 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0735423 |
| FLNA | filamin A, alpha | 0.0613875 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.061218 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0583744 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0577616 |
| PGK1 | phosphoglycerate kinase 1 | 0.0573395 |
| STC1 | stanniocalcin 1 | 0.0550348 |
| INHBA | inhibin, beta A | 0.0543697 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0530472 |
| FN1 | fibronectin 1 | 0.049362 |
| PDIA4 | protein disulfide isomerase family A, member 4 | 0.0492415 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0487801 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0483178 |
| APP | amyloid beta (A4) precursor protein | 0.0482007 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0480093 |
| MT2A | metallothionein 2A | 0.0468155 |
| MAD1L1 | MAD1 mitotic arrest deficient-like 1 (yeast) | 0.0464792 |
| COPA | coatomer protein complex, subunit alpha | 0.0457654 |
| ARHGEF2 | Rho/Rac guanine nucleotide exchange factor (GEF) 2 | 0.0456421 |
| HDAC9 | histone deacetylase 9 | 0.0444984 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0437492 |
| COL5A1 | collagen, type V, alpha 1 | 0.0436488 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0417711 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.040335 |
| TLN1 | talin 1 | 0.0395687 |
| PLEC | plectin | 0.0387298 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0385343 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | 0.0380351 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0379267 |
| RPL13A | ribosomal protein L13a | 0.0356601 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0356505 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0348621 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0340577 |
| GOLGA3 | golgin A3 | 0.033789 |
| PHF3 | PHD finger protein 3 | 0.0324833 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0322679 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0320627 |
| RPL27A | ribosomal protein L27a | 0.0319687 |
| HDLBP | high density lipoprotein binding protein | 0.0319128 |
| SUPT5H | suppressor of Ty 5 homolog (S. cerevisiae) | 0.0314146 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0308537 |
| TMF1 | TATA element modulatory factor 1 | 0.0306352 |
| LOXL2 | lysyl oxidase-like 2 | 0.0304064 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0300251 |
| SUCO | SUN domain containing ossification factor | 0.0298914 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0298151 |
| HYOU1 | hypoxia up-regulated 1 | 0.0295283 |
| IGFBP5 | insulin-like growth factor binding protein 5 | 0.0289466 |
| RPS4X | ribosomal protein S4, X-linked | 0.0286118 |
| UBC | ubiquitin C | 0.0284507 |
| ELP2 | elongator acetyltransferase complex subunit 2 | 0.028296 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0280913 |
| GPR107 | G protein-coupled receptor 107 | 0.028085 |
| ZNF146 | zinc finger protein 146 | 0.0280657 |
| GOLGA4 | golgin A4 | 0.027779 |
| CALU | calumenin | 0.0275464 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | 0.0275009 |
| CDPF1 | cysteine-rich, DPF motif domain containing 1 | 0.027189 |
| FNIP1 | folliculin interacting protein 1 | 0.0271396 |
| COPB1 | coatomer protein complex, subunit beta 1 | 0.0269322 |
| PMM2 | phosphomannomutase 2 | 0.0268388 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0266021 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0265981 |
| LDHA | lactate dehydrogenase A | 0.0265806 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0262536 |
| SEC23A | Sec23 homolog A (S. cerevisiae) | 0.0261513 |
| ZKSCAN1 | zinc finger with KRAB and SCAN domains 1 | 0.0258476 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0250851 |
| CD109 | CD109 molecule | 0.0249858 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0249158 |
| DGKD | diacylglycerol kinase, delta 130kDa | 0.024596 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0245637 |
| RARS1 | arginyl-tRNA synthetase 1 | 0.024512 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0243847 |
| TPM3 | tropomyosin 3 | 0.024122 |
| CCDC47 | coiled-coil domain containing 47 | 0.0241016 |
| ZNF395 | zinc finger protein 395 | 0.0240321 |
| TNNC1 | troponin C type 1 (slow) | 0.0236263 |
| ZC3H11A | zinc finger CCCH-type containing 11A | 0.0234206 |
| RLIM | ring finger protein, LIM domain interacting | 0.0231957 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0231887 |
| PLAUR | plasminogen activator, urokinase receptor | 0.0231093 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | 0.0230179 |
| GDF15 | growth differentiation factor 15 | 0.0230124 |
| SUPT6H | suppressor of Ty 6 homolog (S. cerevisiae) | 0.0228786 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0226087 |
| TNRC18 | trinucleotide repeat containing 18 | 0.0225655 |
| MCL1 | myeloid cell leukemia 1 | 0.0225532 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0225349 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0224469 |
| HELZ | helicase with zinc finger | 0.0221828 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0220376 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.133121 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0819113 |
| FTL | ferritin, light polypeptide | -0.0819028 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0716988 |
| EGR1 | early growth response 1 | -0.0669042 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0627972 |
| GLIS3 | GLIS family zinc finger 3 | -0.0596641 |
| POTEF | POTE ankyrin domain family, member F | -0.0543836 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0536874 |
| NLGN1 | neuroligin 1 | -0.0515666 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0512294 |
| CD44 | CD44 molecule (Indian blood group) | -0.0480969 |
| GRB10 | growth factor receptor-bound protein 10 | -0.047881 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0466415 |
| TMSB10 | thymosin beta 10 | -0.0453509 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0443979 |
| RPS6 | ribosomal protein S6 | -0.0422778 |
| MAP1B | microtubule-associated protein 1B | -0.0417666 |
| OSMR | oncostatin M receptor | -0.0402539 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0400752 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0377082 |
| GPC6 | glypican 6 | -0.0372126 |
| RTN4 | reticulon 4 | -0.0363933 |
| HIBADH | 3-hydroxyisobutyrate dehydrogenase | -0.0358674 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | -0.0346839 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0342095 |
| ATXN1 | ataxin 1 | -0.0340095 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0334977 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | -0.0334369 |
| PTK2 | protein tyrosine kinase 2 | -0.0319213 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.0314113 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0308698 |
| AHR | aryl hydrocarbon receptor | -0.028879 |
| IL6ST | interleukin 6 signal transducer | -0.0288729 |
| IER3 | immediate early response 3 | -0.0285988 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0280648 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | -0.0271424 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | -0.0271113 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0262902 |
| ANXA2 | annexin A2 | -0.0259743 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0258502 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0258033 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0254566 |
| FBXO11 | F-box protein 11 | -0.0253695 |
| TAPBP | TAP binding protein (tapasin) | -0.025353 |
| PHIP | pleckstrin homology domain interacting protein | -0.0252212 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | -0.025149 |
| CBX3 | chromobox homolog 3 | -0.024886 |
| HMGA1 | high mobility group AT-hook 1 | -0.024839 |
| TXNRD1 | thioredoxin reductase 1 | -0.0246889 |
| RPL35A | ribosomal protein L35a | -0.0241615 |
| CADM1 | cell adhesion molecule 1 | -0.0241008 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0239225 |
| PKM | pyruvate kinase, muscle | -0.0237374 |
| SEPTIN7 | septin 7 | -0.0237243 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | -0.0234115 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0225779 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0225351 |
| TUSC3 | tumor suppressor candidate 3 | -0.0224475 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0221637 |
| ALPK1 | alpha-kinase 1 | -0.02169 |
| BZW2 | basic leucine zipper and W2 domains 2 | -0.0215798 |
| TENM3 | teneurin transmembrane protein 3 | -0.0215274 |
| PTPRD | protein tyrosine phosphatase, receptor type, D | -0.0211281 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | -0.0208125 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0207791 |
| RPL28 | ribosomal protein L28 | -0.0206928 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0204853 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0204848 |
| SENP6 | SUMO1/sentrin specific peptidase 6 | -0.0204337 |
| LOX | lysyl oxidase | -0.0203212 |
| RBMS1 | RNA binding motif, single stranded interacting protein 1 | -0.0202822 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0202324 |
| ASTN2 | astrotactin 2 | -0.0202019 |
| SRPK2 | SRSF protein kinase 2 | -0.0200425 |
| FBXL17 | F-box and leucine-rich repeat protein 17 | -0.0200061 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0199379 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0196491 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0195239 |
| EYA4 | EYA transcriptional coactivator and phosphatase 4 | -0.0195058 |
| JMJD1C | jumonji domain containing 1C | -0.0191935 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0191487 |
| GPHN | gephyrin | -0.0188278 |
| TENT4A | terminal nucleotidyltransferase 4A | -0.0187958 |
| CCNL1 | cyclin L1 | -0.0187904 |
| ATF7IP | activating transcription factor 7 interacting protein | -0.0187564 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0186692 |
| CENPE | centromere protein E, 312kDa | -0.0186053 |
| RPL30 | ribosomal protein L30 | -0.018374 |
| PCNX1 | pecanex 1 | -0.0182913 |
| RUNX1 | runt-related transcription factor 1 | -0.0182299 |
| RPS19 | ribosomal protein S19 | -0.0181091 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0180769 |
| TMOD3 | tropomodulin 3 (ubiquitous) | -0.0180303 |
| FOSL1 | FOS-like antigen 1 | -0.0179883 |
| CUX1 | cut-like homeobox 1 | -0.0178935 |
| RPS20 | ribosomal protein S20 | -0.0178529 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0177149 |
| CREB3L2 | cAMP responsive element binding protein 3-like 2 | -0.0176858 |
| TPST1 | tyrosylprotein sulfotransferase 1 | -0.0176615 |
