| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Crizotinib (hydrochloride) perturbation in HEC-1-A cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Crizotinib (hydrochloride)_HEC-1-A drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MYH9 | myosin, heavy chain 9, non-muscle | 0.128626 |
| FLNA | filamin A, alpha | 0.0853643 |
| APP | amyloid beta (A4) precursor protein | 0.0590888 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0402522 |
| PRELID2 | PRELI domain containing 2 | 0.0396074 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0391496 |
| PLEC | plectin | 0.0360434 |
| SMAD3 | SMAD family member 3 | 0.0352644 |
| VCL | vinculin | 0.0348006 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0303029 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0294554 |
| OGA | O-GlcNAcase | 0.0291167 |
| RPS4X | ribosomal protein S4, X-linked | 0.0245819 |
| TMSB4X | thymosin beta 4, X-linked | 0.0238992 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0234759 |
| ACTN4 | actinin, alpha 4 | 0.0227208 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0224512 |
| RPL14 | ribosomal protein L14 | 0.0222709 |
| ANXA11 | annexin A11 | 0.0221023 |
| TJP1 | tight junction protein 1 | 0.0218611 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0215386 |
| AFDN | afadin, adherens junction formation factor | 0.021167 |
| ARGLU1 | arginine and glutamate rich 1 | 0.0209446 |
| KRT18 | keratin 18, type I | 0.0209125 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0205962 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0204653 |
| DDX3X | DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked | 0.0203194 |
| PPL | periplakin | 0.0200799 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0196855 |
| RPL4 | ribosomal protein L4 | 0.0188076 |
| AHNAK | AHNAK nucleoprotein | 0.0187921 |
| RNF213 | ring finger protein 213 | 0.0187197 |
| AHNAK2 | AHNAK nucleoprotein 2 | 0.0184402 |
| DIAPH1 | diaphanous-related formin 1 | 0.0181009 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | 0.0175491 |
| DSPP | dentin sialophosphoprotein | 0.0174652 |
| NUMA1 | nuclear mitotic apparatus protein 1 | 0.0171059 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.01701 |
| POU5F1 | POU class 5 homeobox 1 | 0.0168973 |
| PHF3 | PHD finger protein 3 | 0.016703 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0162078 |
| LASP1 | LIM and SH3 protein 1 | 0.0160937 |
| CANX | calnexin | 0.0157511 |
| RPL7 | ribosomal protein L7 | 0.015631 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0151634 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0150211 |
| RPL13A | ribosomal protein L13a | 0.0149972 |
| CEP250 | centrosomal protein 250kDa | 0.0149271 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0148154 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0143718 |
| MKI67 | marker of proliferation Ki-67 | 0.014125 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.014118 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0136524 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0135327 |
| SPAG5 | sperm associated antigen 5 | 0.0135278 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0130219 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0129352 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | 0.0128441 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.0127638 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0127552 |
| SERINC1 | serine incorporator 1 | 0.0127287 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | 0.0126509 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0125718 |
| DPP4 | dipeptidyl-peptidase 4 | 0.0124811 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0123388 |
| TNFAIP2 | tumor necrosis factor, alpha-induced protein 2 | 0.0123298 |
| RPL3 | ribosomal protein L3 | 0.0122553 |
| KDM5C | lysine (K)-specific demethylase 5C | 0.0121537 |
| H1-4 | H1.4 linker histone, cluster member | 0.0121022 |
| CORO1C | coronin, actin binding protein, 1C | 0.0117978 |
| SCRN1 | secernin 1 | 0.0116344 |
| FDPS | farnesyl diphosphate synthase | 0.0116108 |
| H1-2 | H1.2 linker histone, cluster member | 0.0114207 |
| MACROD2 | MACRO domain containing 2 | 0.0113926 |
| WWOX | WW domain containing oxidoreductase | 0.0112921 |
| TBC1D9B | TBC1 domain family, member 9B (with GRAM domain) | 0.0112778 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0111972 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.011187 |
| JADE2 | jade family PHD finger 2 | 0.011091 |
| DHRS3 | dehydrogenase/reductase (SDR family) member 3 | 0.0110312 |
| HNRNPR | heterogeneous nuclear ribonucleoprotein R | 0.0110185 |
| SEPTIN9 | septin 9 | 0.0109849 |
| GYS1 | glycogen synthase 1 (muscle) | 0.0109607 |
| BAZ1B | bromodomain adjacent to zinc finger domain, 1B | 0.0108529 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0107364 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0106975 |
| PHC3 | polyhomeotic homolog 3 (Drosophila) | 0.0106735 |
| TGFBR1 | transforming growth factor, beta receptor 1 | 0.0106617 |
| PCLO | piccolo presynaptic cytomatrix protein | 0.0105853 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0105688 |
| ABCC3 | ATP-binding cassette, sub-family C (CFTR/MRP), member 3 | 0.0105483 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.010477 |
| ANKRD36 | ankyrin repeat domain 36 | 0.0104058 |
| TAB2 | TGF-beta activated kinase 1/MAP3K7 binding protein 2 | 0.0103027 |
| ZNF608 | zinc finger protein 608 | 0.0102239 |
| ST13 | suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein) | 0.0101559 |
| CUL3 | cullin 3 | 0.0101252 |
| CHD3 | chromodomain helicase DNA binding protein 3 | 0.0100783 |
| HNRNPD | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) | 0.0100145 |
| KAZN | kazrin, periplakin interacting protein | 0.010008 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0878904 |
| NDRG1 | N-myc downstream regulated 1 | -0.0872748 |
| MT2A | metallothionein 2A | -0.0789694 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0717126 |
| TMSB10 | thymosin beta 10 | -0.0700543 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0587539 |
| POTEF | POTE ankyrin domain family, member F | -0.0584621 |
| ACTG1 | actin gamma 1 | -0.0578428 |
| EGR1 | early growth response 1 | -0.0519559 |
| HMGA1 | high mobility group AT-hook 1 | -0.0513282 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -0.0468839 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0466193 |
| FTL | ferritin, light polypeptide | -0.0446311 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0440162 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.0421958 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0419904 |
| DLC1 | DLC1 Rho GTPase activating protein | -0.0400083 |
| ANXA2 | annexin A2 | -0.0398735 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0398027 |
| CD44 | CD44 molecule (Indian blood group) | -0.037733 |
| TXNRD1 | thioredoxin reductase 1 | -0.0356543 |
| EGFR | epidermal growth factor receptor | -0.0355548 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.035282 |
| LDHA | lactate dehydrogenase A | -0.0336134 |
| PKM | pyruvate kinase, muscle | -0.031998 |
| HMGA2 | high mobility group AT-hook 2 | -0.0316371 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.030892 |
| CCND1 | cyclin D1 | -0.0308052 |
| GOLGA4 | golgin A4 | -0.0307906 |
| MAP4 | microtubule-associated protein 4 | -0.030654 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0305346 |
| RUNX1 | runt-related transcription factor 1 | -0.0301185 |
| PTMA | prothymosin, alpha | -0.0284256 |
| BPTF | bromodomain PHD finger transcription factor | -0.0273957 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0271675 |
| CREB5 | cAMP responsive element binding protein 5 | -0.0266453 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0262245 |
| TPM4 | tropomyosin 4 | -0.025869 |
| ANXA1 | annexin A1 | -0.0255806 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0254522 |
| ENO1 | enolase 1, (alpha) | -0.0253172 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0251574 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0250038 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0249373 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0245918 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0244855 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0240592 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0239839 |
| NF1 | neurofibromin 1 | -0.0238611 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0238601 |
| VMP1 | vacuole membrane protein 1 | -0.0238363 |
| KRT7 | keratin 7, type II | -0.0234437 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | -0.0233622 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0232229 |
| SVIL | supervillin | -0.0232055 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0232048 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0223832 |
| B2M | beta-2-microglobulin | -0.0218214 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | -0.0217841 |
| FLNB | filamin B, beta | -0.0217627 |
| TES | testin LIM domain protein | -0.021339 |
| FOSL1 | FOS-like antigen 1 | -0.0212627 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0210603 |
| LAMA4 | laminin, alpha 4 | -0.0209239 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0208985 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | -0.0206352 |
| MYADM | myeloid-associated differentiation marker | -0.0204175 |
| RPL35A | ribosomal protein L35a | -0.0201989 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.0198595 |
| SEC24D | SEC24 family member D | -0.0194153 |
| PTK2 | protein tyrosine kinase 2 | -0.0194101 |
| VDAC1 | voltage-dependent anion channel 1 | -0.019122 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | -0.0186211 |
| DOCK4 | dedicator of cytokinesis 4 | -0.018508 |
| FBXL2 | F-box and leucine-rich repeat protein 2 | -0.0184539 |
| PFN1 | profilin 1 | -0.0184307 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0183553 |
| SEC24A | SEC24 family member A | -0.0183216 |
| CMSS1 | cms1 ribosomal small subunit homolog (yeast) | -0.0182186 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | -0.0182048 |
| RPS6 | ribosomal protein S6 | -0.0180994 |
| ZNF292 | zinc finger protein 292 | -0.0180688 |
| BIRC3 | baculoviral IAP repeat containing 3 | -0.0177096 |
| PARD3 | par-3 family cell polarity regulator | -0.0176761 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0175982 |
| RACK1 | receptor for activated C kinase 1 | -0.0175209 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0174037 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.017385 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | -0.0173206 |
| WDR45B | WD repeat domain 45B | -0.017261 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | -0.0172451 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0171589 |
| FBXO11 | F-box protein 11 | -0.0171123 |
| ARHGAP29 | Rho GTPase activating protein 29 | -0.0170867 |
| RNF145 | ring finger protein 145 | -0.0168987 |
| CALR | calreticulin | -0.0165908 |
| ECT2 | epithelial cell transforming 2 | -0.0165876 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.016449 |
| SBF2 | SET binding factor 2 | -0.016324 |
| S100A10 | S100 calcium binding protein A10 | -0.0161109 |
