| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Crizotinib (hydrochloride) perturbation in HOP62 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Crizotinib (hydrochloride)_HOP62 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | 0.338527 |
| FN1 | fibronectin 1 | 0.161362 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.131666 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0957689 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0919454 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0893324 |
| COL6A1 | collagen, type VI, alpha 1 | 0.0873702 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0869582 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0835568 |
| FLNA | filamin A, alpha | 0.0649628 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0648821 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | 0.0619966 |
| FLNB | filamin B, beta | 0.0578223 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0504727 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0498506 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.04976 |
| PLEC | plectin | 0.0494902 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0493038 |
| SEPTIN9 | septin 9 | 0.0472622 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0469548 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0448693 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0441444 |
| NAV2 | neuron navigator 2 | 0.0441321 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0435585 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0422779 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | 0.0422099 |
| OGA | O-GlcNAcase | 0.0405238 |
| CDCP1 | CUB domain containing protein 1 | 0.0398257 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0392159 |
| SMAD3 | SMAD family member 3 | 0.038502 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0377964 |
| NDRG1 | N-myc downstream regulated 1 | 0.0366269 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | 0.036029 |
| FAM13A | family with sequence similarity 13, member A | 0.0352293 |
| LAMB3 | laminin, beta 3 | 0.0345962 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0342728 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | 0.0338594 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0337355 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0332073 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | 0.0331155 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0328584 |
| APP | amyloid beta (A4) precursor protein | 0.031975 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0319631 |
| VEGFA | vascular endothelial growth factor A | 0.0318046 |
| HPCAL1 | hippocalcin-like 1 | 0.0316647 |
| NGLY1 | N-glycanase 1 | 0.0312519 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0302516 |
| MSN | moesin | 0.0298284 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.029812 |
| CEP250 | centrosomal protein 250kDa | 0.0297573 |
| SETD5 | SET domain containing 5 | 0.0296183 |
| RRBP1 | ribosome binding protein 1 | 0.029502 |
| AFDN | afadin, adherens junction formation factor | 0.0295014 |
| EPN2 | epsin 2 | 0.0294557 |
| RUNX1 | runt-related transcription factor 1 | 0.0292068 |
| TAC4 | tachykinin 4 (hemokinin) | 0.02888 |
| DUSP6 | dual specificity phosphatase 6 | 0.0286875 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0280973 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0279046 |
| AMPD3 | adenosine monophosphate deaminase 3 | 0.0276588 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0273803 |
| MAP2K1 | mitogen-activated protein kinase kinase 1 | 0.0270247 |
| VASP | vasodilator-stimulated phosphoprotein | 0.0269544 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0268727 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0268196 |
| FMNL2 | formin-like 2 | 0.0265022 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.025551 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0252408 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0251247 |
| STC1 | stanniocalcin 1 | 0.0250682 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) | 0.0250264 |
| HP1BP3 | heterochromatin protein 1, binding protein 3 | 0.0249132 |
| ACTN4 | actinin, alpha 4 | 0.0245141 |
| TMEM165 | transmembrane protein 165 | 0.0242969 |
| GOLGA4 | golgin A4 | 0.0242203 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.0241137 |
| PLAUR | plasminogen activator, urokinase receptor | 0.0240289 |
| TSPAN5 | tetraspanin 5 | 0.0233158 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | 0.0233154 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.0232057 |
| MYO9B | myosin IXB | 0.0230704 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0229865 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.0229847 |
| AFF4 | AF4/FMR2 family, member 4 | 0.0221633 |
| YEATS2 | YEATS domain containing 2 | 0.0219128 |
| LOXL2 | lysyl oxidase-like 2 | 0.0218198 |
| ST3GAL6 | ST3 beta-galactoside alpha-2,3-sialyltransferase 6 | 0.021751 |
| ZNF146 | zinc finger protein 146 | 0.0217437 |
| MLPH | melanophilin | 0.02163 |
| TMF1 | TATA element modulatory factor 1 | 0.021607 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0215194 |
| DOT1L | DOT1-like histone H3K79 methyltransferase | 0.0213588 |
| RASA3 | RAS p21 protein activator 3 | 0.0210649 |
| CANX | calnexin | 0.0209537 |
| LASP1 | LIM and SH3 protein 1 | 0.0208755 |
| NIPBL | Nipped-B homolog (Drosophila) | 0.0207478 |
| PTPN1 | protein tyrosine phosphatase, non-receptor type 1 | 0.0206928 |
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.0205725 |
| MYO1B | myosin IB | 0.0203844 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0203472 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.116462 |
| EGR1 | early growth response 1 | -0.0973177 |
| CD44 | CD44 molecule (Indian blood group) | -0.0968229 |
| HMGA2 | high mobility group AT-hook 2 | -0.0957203 |
| GLIS3 | GLIS family zinc finger 3 | -0.0865884 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0833296 |
| IGF2 | insulin-like growth factor 2 | -0.0697864 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | -0.0697104 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0696051 |
| ACTG1 | actin gamma 1 | -0.0691691 |
| VCL | vinculin | -0.0659885 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0619547 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0601245 |
| TMSB10 | thymosin beta 10 | -0.0582617 |
| LOX | lysyl oxidase | -0.0509732 |
| CDH13 | cadherin 13 | -0.049584 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0429734 |
| ANTXR1 | anthrax toxin receptor 1 | -0.0421191 |
| CCND1 | cyclin D1 | -0.0415653 |
| NAV1 | neuron navigator 1 | -0.0379508 |
| IER3 | immediate early response 3 | -0.0367685 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0364608 |
| NABP1 | nucleic acid binding protein 1 | -0.035112 |
| SMYD3 | SET and MYND domain containing 3 | -0.0335676 |
| PTMA | prothymosin, alpha | -0.0330309 |
| FMN1 | formin 1 | -0.0314659 |
| RAD51B | RAD51 paralog B | -0.0314603 |
| TENM2 | teneurin transmembrane protein 2 | -0.0298233 |
| VMP1 | vacuole membrane protein 1 | -0.0291578 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | -0.0282761 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0282104 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | -0.0279508 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0273433 |
| FTL | ferritin, light polypeptide | -0.0269451 |
| TPM1 | tropomyosin 1 (alpha) | -0.024919 |
| ANXA2 | annexin A2 | -0.0239702 |
| INTS6 | integrator complex subunit 6 | -0.0238988 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0237552 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0236721 |
| CCDC91 | coiled-coil domain containing 91 | -0.0230744 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0228643 |
| POTEF | POTE ankyrin domain family, member F | -0.0219883 |
| THBS1 | thrombospondin 1 | -0.0216954 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0214831 |
| DST | dystonin | -0.0211593 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0210933 |
| MPRIP | myosin phosphatase Rho interacting protein | -0.0210869 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | -0.0210453 |
| RPL28 | ribosomal protein L28 | -0.0209741 |
| CEP112 | centrosomal protein 112kDa | -0.020498 |
| RPS19 | ribosomal protein S19 | -0.0202562 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.020221 |
| EXOC4 | exocyst complex component 4 | -0.0200799 |
| TNNC1 | troponin C type 1 (slow) | -0.019931 |
| ANKRD28 | ankyrin repeat domain 28 | -0.019619 |
| WWOX | WW domain containing oxidoreductase | -0.019473 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0194452 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0193391 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.019061 |
| BCAT1 | branched chain amino-acid transaminase 1, cytosolic | -0.0190549 |
| KLF12 | Kruppel-like factor 12 | -0.0189606 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) | -0.0187968 |
| LRMDA | leucine rich melanocyte differentiation associated | -0.0187507 |
| PRH1 | proline-rich protein HaeIII subfamily 1 | -0.0186676 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | -0.0186405 |
| RPS6 | ribosomal protein S6 | -0.0181495 |
| CDK6 | cyclin-dependent kinase 6 | -0.0178583 |
| RPL35A | ribosomal protein L35a | -0.0178489 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | -0.017783 |
| CDKAL1 | CDK5 regulatory subunit associated protein 1-like 1 | -0.0177461 |
| IGFBP4 | insulin-like growth factor binding protein 4 | -0.0177283 |
| SPIDR | scaffolding protein involved in DNA repair | -0.017702 |
| IL1B | interleukin 1, beta | -0.0174668 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0172011 |
| BBS9 | Bardet-Biedl syndrome 9 | -0.0171267 |
| RPL12 | ribosomal protein L12 | -0.0170155 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0167668 |
| SHISA5 | shisa family member 5 | -0.0167463 |
| PALLD | palladin, cytoskeletal associated protein | -0.0164784 |
| MT2A | metallothionein 2A | -0.01634 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0161092 |
| RPL37A | ribosomal protein L37a | -0.0160058 |
| MYO10 | myosin X | -0.0159517 |
| CALR | calreticulin | -0.0157857 |
| ATG7 | autophagy related 7 | -0.0154274 |
| CCDC138 | coiled-coil domain containing 138 | -0.015424 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0152766 |
| NEK11 | NIMA-related kinase 11 | -0.0150485 |
| EHBP1 | EH domain binding protein 1 | -0.0149839 |
| ALDH1A3 | aldehyde dehydrogenase 1 family, member A3 | -0.0148905 |
| RPL5 | ribosomal protein L5 | -0.0147806 |
| EPAS1 | endothelial PAS domain protein 1 | -0.014691 |
| PODXL | podocalyxin-like | -0.0146214 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | -0.0145262 |
| PCBP3 | poly(rC) binding protein 3 | -0.0145193 |
| BPTF | bromodomain PHD finger transcription factor | -0.0145075 |
| PFN1 | profilin 1 | -0.0144828 |
| NLK | nemo-like kinase | -0.0144616 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | -0.0144145 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | -0.0143708 |
