| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Crizotinib (hydrochloride) perturbation in HT-29 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Crizotinib (hydrochloride)_HT-29 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.13974 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0966778 |
| KRT18 | keratin 18, type I | 0.0936097 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0927286 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0751432 |
| VEGFA | vascular endothelial growth factor A | 0.0731143 |
| HYOU1 | hypoxia up-regulated 1 | 0.0656088 |
| LYZ | lysozyme | 0.0617436 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0600261 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0503449 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.047906 |
| PDIA4 | protein disulfide isomerase family A, member 4 | 0.0460075 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0447748 |
| PCBP2 | poly(rC) binding protein 2 | 0.0386584 |
| ARGLU1 | arginine and glutamate rich 1 | 0.038548 |
| CANX | calnexin | 0.0376487 |
| MCL1 | myeloid cell leukemia 1 | 0.0375953 |
| SPCS2 | signal peptidase complex subunit 2 homolog (S. cerevisiae) | 0.0367593 |
| TPM3 | tropomyosin 3 | 0.0366557 |
| EPS8L1 | EPS8-like 1 | 0.0359009 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0357268 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0354646 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0335261 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0322179 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0320112 |
| MSN | moesin | 0.0305678 |
| FLNA | filamin A, alpha | 0.0300453 |
| GCNT3 | glucosaminyl (N-acetyl) transferase 3, mucin type | 0.0298451 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0298336 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0297048 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0295019 |
| SUPT5H | suppressor of Ty 5 homolog (S. cerevisiae) | 0.0288478 |
| CALR | calreticulin | 0.0288385 |
| KRT19 | keratin 19, type I | 0.028779 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0287013 |
| VIM | vimentin | 0.0283381 |
| ANXA11 | annexin A11 | 0.0282775 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0278951 |
| HNRNPR | heterogeneous nuclear ribonucleoprotein R | 0.0274063 |
| SEPTIN9 | septin 9 | 0.0269526 |
| NUMA1 | nuclear mitotic apparatus protein 1 | 0.026832 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0265813 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0265116 |
| BRD2 | bromodomain containing 2 | 0.0264892 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0257317 |
| TNS1 | tensin 1 | 0.0253603 |
| RPL13A | ribosomal protein L13a | 0.0252813 |
| AARS1 | alanyl-tRNA synthetase 1 | 0.025033 |
| ATF4 | activating transcription factor 4 | 0.0248448 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.024844 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0247623 |
| RPS3 | ribosomal protein S3 | 0.0247109 |
| TMF1 | TATA element modulatory factor 1 | 0.0236707 |
| PNN | pinin, desmosome associated protein | 0.0234886 |
| RPL21 | ribosomal protein L21 | 0.0233396 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 | 0.0232453 |
| LMO7 | LIM domain 7 | 0.0231694 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0229188 |
| RPL3 | ribosomal protein L3 | 0.0222328 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0220306 |
| PGK1 | phosphoglycerate kinase 1 | 0.0220173 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | 0.0220134 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0217214 |
| HDGF | hepatoma-derived growth factor | 0.0216892 |
| ACBD3 | acyl-CoA binding domain containing 3 | 0.0216639 |
| DSPP | dentin sialophosphoprotein | 0.0215206 |
| CNOT12 | CCR4-NOT transcription complex subunit 12 | 0.0212911 |
| RPL7 | ribosomal protein L7 | 0.0210547 |
| FAM13A | family with sequence similarity 13, member A | 0.0203447 |
| PLK2 | polo-like kinase 2 | 0.0203057 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0202183 |
| SET | SET nuclear proto-oncogene | 0.0200518 |
| PLEC | plectin | 0.0196689 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | 0.0195702 |
| MAPK6 | mitogen-activated protein kinase 6 | 0.019546 |
| LDHA | lactate dehydrogenase A | 0.0195425 |
| DDX3X | DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked | 0.0193909 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0192676 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0192577 |
| RPS18 | ribosomal protein S18 | 0.0192132 |
| ANP32B | acidic (leucine-rich) nuclear phosphoprotein 32 family, member B | 0.0187077 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | 0.0186494 |
| TUFT1 | tuftelin 1 | 0.0186352 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.0186121 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0185165 |
| YME1L1 | YME1-like 1 ATPase | 0.0184495 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0184415 |
| SMAD3 | SMAD family member 3 | 0.0181735 |
| KDM5C | lysine (K)-specific demethylase 5C | 0.0181643 |
| CLPTM1L | CLPTM1-like | 0.0179709 |
| GOLPH3 | golgi phosphoprotein 3 (coat-protein) | 0.0178207 |
| RNASE1 | ribonuclease, RNase A family, 1 (pancreatic) | 0.0176287 |
| OS9 | osteosarcoma amplified 9, endoplasmic reticulum lectin | 0.0175618 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0175234 |
| HNRNPUL2 | heterogeneous nuclear ribonucleoprotein U-like 2 | 0.01738 |
| IER2 | immediate early response 2 | 0.0172532 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0172271 |
| PPP6R1 | protein phosphatase 6, regulatory subunit 1 | 0.017225 |
| ST14 | suppression of tumorigenicity 14 (colon carcinoma) | 0.0172105 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | 0.0170758 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.227481 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.194283 |
| FTL | ferritin, light polypeptide | -0.125982 |
| RPLP1 | ribosomal protein, large, P1 | -0.125031 |
| ACTG1 | actin gamma 1 | -0.120508 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.104037 |
| RPL35A | ribosomal protein L35a | -0.10181 |
| RPS21 | ribosomal protein S21 | -0.0874835 |
| AHNAK | AHNAK nucleoprotein | -0.0824974 |
| NF1 | neurofibromin 1 | -0.0756191 |
| RPL34 | ribosomal protein L34 | -0.0743555 |
| ANXA2 | annexin A2 | -0.0722939 |
| RTN3 | reticulon 3 | -0.0691454 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | -0.067394 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0655833 |
| RPS6 | ribosomal protein S6 | -0.064718 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0634411 |
| RPS24 | ribosomal protein S24 | -0.061169 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0602453 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0599063 |
| TXNRD1 | thioredoxin reductase 1 | -0.0591158 |
| TMEM123 | transmembrane protein 123 | -0.0585516 |
| CD2AP | CD2-associated protein | -0.0575557 |
| RPS13 | ribosomal protein S13 | -0.0573457 |
| S100A10 | S100 calcium binding protein A10 | -0.0563218 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0555386 |
| TMSB10 | thymosin beta 10 | -0.0554855 |
| ROCK2 | Rho-associated, coiled-coil containing protein kinase 2 | -0.0542979 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0541927 |
| RPS8 | ribosomal protein S8 | -0.0519901 |
| RPS5 | ribosomal protein S5 | -0.0508383 |
| RPLP0 | ribosomal protein, large, P0 | -0.0507231 |
| PTK2 | protein tyrosine kinase 2 | -0.0498735 |
| PARP4 | poly (ADP-ribose) polymerase family, member 4 | -0.0497676 |
| S100A6 | S100 calcium binding protein A6 | -0.0496798 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | -0.0494717 |
| AGR2 | anterior gradient 2 | -0.048083 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0476904 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0461386 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0456808 |
| RPS19 | ribosomal protein S19 | -0.0455072 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0444998 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0440568 |
| ASNS | asparagine synthetase (glutamine-hydrolyzing) | -0.0437612 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0436015 |
| ST3GAL1 | ST3 beta-galactoside alpha-2,3-sialyltransferase 1 | -0.0432852 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0429811 |
| RPS16 | ribosomal protein S16 | -0.0424025 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0421276 |
| RPL27A | ribosomal protein L27a | -0.0417121 |
| EIF3H | eukaryotic translation initiation factor 3, subunit H | -0.0415937 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0414354 |
| EPCAM | epithelial cell adhesion molecule | -0.0406023 |
| BPTF | bromodomain PHD finger transcription factor | -0.0402962 |
| ASTN2 | astrotactin 2 | -0.0401278 |
| HMGB1 | high mobility group box 1 | -0.0400437 |
| NSMCE2 | non-SMC element 2, MMS21 homolog (S. cerevisiae) | -0.0398813 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.039642 |
| GNAS | GNAS complex locus | -0.0384064 |
| TMEM65 | transmembrane protein 65 | -0.0383466 |
| ELF2 | E74-like factor 2 (ets domain transcription factor) | -0.0379739 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | -0.037509 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0371945 |
| RPL30 | ribosomal protein L30 | -0.0367855 |
| EXPH5 | exophilin 5 | -0.0365878 |
| RPL8 | ribosomal protein L8 | -0.0359527 |
| KRT20 | keratin 20, type I | -0.0357417 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0356197 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | -0.0355489 |
| USP3 | ubiquitin specific peptidase 3 | -0.0353846 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.035179 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0350976 |
| RPS23 | ribosomal protein S23 | -0.0348895 |
| CCSER1 | coiled-coil serine-rich protein 1 | -0.0348685 |
| RRBP1 | ribosome binding protein 1 | -0.0345434 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0343303 |
| RPL28 | ribosomal protein L28 | -0.0342625 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0339696 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0338474 |
| ARF1 | ADP-ribosylation factor 1 | -0.0334863 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0334527 |
| ZNF207 | zinc finger protein 207 | -0.0331665 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0328329 |
| RHEB | Ras homolog enriched in brain | -0.0326644 |
| RPL32 | ribosomal protein L32 | -0.0321367 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | -0.0320501 |
| TRAPPC9 | trafficking protein particle complex 9 | -0.0317888 |
| RPS11 | ribosomal protein S11 | -0.0317694 |
| H1-0 | H1.0 linker histone | -0.0317398 |
| PRKN | parkin RBR E3 ubiquitin protein ligase | -0.0316408 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0316227 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | -0.0314574 |
| RPLP2 | ribosomal protein, large, P2 | -0.0313867 |
| RPL31 | ribosomal protein L31 | -0.0307627 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | -0.030619 |
| MYO1D | myosin ID | -0.0305862 |
| AGO2 | argonaute RISC catalytic component 2 | -0.0304343 |
| ABCC3 | ATP-binding cassette, sub-family C (CFTR/MRP), member 3 | -0.0300897 |
| ITPKC | inositol-trisphosphate 3-kinase C | -0.0299849 |
| OGA | O-GlcNAcase | -0.0299353 |
