| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Crizotinib (hydrochloride) perturbation in J82 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Crizotinib (hydrochloride)_J82 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0935666 |
| CALR | calreticulin | 0.0714324 |
| FLNA | filamin A, alpha | 0.0645736 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0637593 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0467489 |
| ARGLU1 | arginine and glutamate rich 1 | 0.0423387 |
| CANX | calnexin | 0.0399709 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0394227 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0344377 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0340972 |
| SF3B2 | splicing factor 3b, subunit 2, 145kDa | 0.0329645 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0303715 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0299215 |
| KRT18 | keratin 18, type I | 0.0295926 |
| L1CAM | L1 cell adhesion molecule | 0.0284813 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0276601 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0252551 |
| INTS6 | integrator complex subunit 6 | 0.0245804 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.024287 |
| SMAD3 | SMAD family member 3 | 0.0230191 |
| PDIA4 | protein disulfide isomerase family A, member 4 | 0.0227775 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0205687 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0204366 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.0201554 |
| TLE4 | transducin-like enhancer of split 4 | 0.020076 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0198223 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | 0.0196832 |
| HLA-E | major histocompatibility complex, class I, E | 0.0195805 |
| DDX3X | DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked | 0.0193444 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.0192122 |
| VCL | vinculin | 0.0191665 |
| RPL13A | ribosomal protein L13a | 0.0189363 |
| DENND5A | DENN/MADD domain containing 5A | 0.0187884 |
| BRD2 | bromodomain containing 2 | 0.0187335 |
| NUMA1 | nuclear mitotic apparatus protein 1 | 0.0186459 |
| SUPT5H | suppressor of Ty 5 homolog (S. cerevisiae) | 0.0186328 |
| HMGB2 | high mobility group box 2 | 0.0185805 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0183755 |
| SEC61A1 | Sec61 alpha 1 subunit (S. cerevisiae) | 0.0182775 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0179269 |
| PTMA | prothymosin, alpha | 0.0177465 |
| PPP1R15B | protein phosphatase 1, regulatory subunit 15B | 0.0176648 |
| SERINC1 | serine incorporator 1 | 0.0176519 |
| NASP | nuclear autoantigenic sperm protein (histone-binding) | 0.0175275 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0174642 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0173247 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.017219 |
| ELOVL5 | ELOVL fatty acid elongase 5 | 0.0166351 |
| HLA-C | major histocompatibility complex, class I, C | 0.0163052 |
| COL7A1 | collagen, type VII, alpha 1 | 0.0161987 |
| PHRF1 | PHD and ring finger domains 1 | 0.0158807 |
| CTNNBL1 | catenin, beta like 1 | 0.0157831 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0157733 |
| DPM1 | dolichyl-phosphate mannosyltransferase polypeptide 1, catalytic subunit | 0.0155493 |
| UBQLN1 | ubiquilin 1 | 0.0154234 |
| ATP13A3 | ATPase type 13A3 | 0.0154079 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0153485 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0153279 |
| FAR1 | fatty acyl CoA reductase 1 | 0.0147031 |
| ACTN4 | actinin, alpha 4 | 0.0146651 |
| EZH2 | enhancer of zeste 2 polycomb repressive complex 2 subunit | 0.0146414 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0143995 |
| PLEC | plectin | 0.0142122 |
| PLK2 | polo-like kinase 2 | 0.0140934 |
| CASC3 | cancer susceptibility candidate 3 | 0.0140118 |
| TFRC | transferrin receptor | 0.0138103 |
| SMG7 | SMG7 nonsense mediated mRNA decay factor | 0.0137925 |
| COL12A1 | collagen, type XII, alpha 1 | 0.0137797 |
| EIF4A3 | eukaryotic translation initiation factor 4A3 | 0.0137681 |
| TGFB2 | transforming growth factor, beta 2 | 0.0135924 |
| NUP153 | nucleoporin 153kDa | 0.0135829 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0135707 |
| ABCF1 | ATP-binding cassette, sub-family F (GCN20), member 1 | 0.0133859 |
| CEP250 | centrosomal protein 250kDa | 0.0132297 |
| APP | amyloid beta (A4) precursor protein | 0.0129772 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.012809 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0128045 |
| BTAF1 | BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa | 0.0127427 |
| RANBP9 | RAN binding protein 9 | 0.0125014 |
| TNFAIP2 | tumor necrosis factor, alpha-induced protein 2 | 0.0124397 |
| RPL14 | ribosomal protein L14 | 0.0124291 |
| ACIN1 | apoptotic chromatin condensation inducer 1 | 0.0123893 |
| SUCO | SUN domain containing ossification factor | 0.0123557 |
| COL4A2 | collagen, type IV, alpha 2 | 0.0123432 |
| TRA2B | transformer 2 beta homolog (Drosophila) | 0.012236 |
| HBP1 | HMG-box transcription factor 1 | 0.0121414 |
| SND1 | staphylococcal nuclease and tudor domain containing 1 | 0.0121083 |
| DDX27 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 27 | 0.0120543 |
| CORO1C | coronin, actin binding protein, 1C | 0.0120321 |
| RAD21 | RAD21 homolog (S. pombe) | 0.0119795 |
| CDC73 | cell division cycle 73 | 0.0119711 |
| LRRC59 | leucine rich repeat containing 59 | 0.0119697 |
| GNL2 | guanine nucleotide binding protein-like 2 (nucleolar) | 0.0118862 |
| IFRD1 | interferon-related developmental regulator 1 | 0.0118344 |
| SLIT2 | slit homolog 2 (Drosophila) | 0.0118141 |
| OS9 | osteosarcoma amplified 9, endoplasmic reticulum lectin | 0.0118084 |
| SEPTIN9 | septin 9 | 0.0116356 |
| RPS9 | ribosomal protein S9 | 0.0115939 |
| GANAB | glucosidase, alpha; neutral AB | 0.0115041 |
| TUFT1 | tuftelin 1 | 0.01149 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.247711 |
| NDRG1 | N-myc downstream regulated 1 | -0.19678 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.173892 |
| FN1 | fibronectin 1 | -0.15859 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.14629 |
| CD44 | CD44 molecule (Indian blood group) | -0.128394 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.122619 |
| MT2A | metallothionein 2A | -0.115441 |
| HLA-B | major histocompatibility complex, class I, B | -0.112185 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -0.0977876 |
| POTEF | POTE ankyrin domain family, member F | -0.0972342 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0893717 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0828792 |
| ENO1 | enolase 1, (alpha) | -0.0794155 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0753005 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.0750771 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0733618 |
| RPS6 | ribosomal protein S6 | -0.0718078 |
| ACTG1 | actin gamma 1 | -0.0714591 |
| DEK | DEK proto-oncogene | -0.0661559 |
| PHACTR1 | phosphatase and actin regulator 1 | -0.0649562 |
| ANXA2 | annexin A2 | -0.063294 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0618466 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0566292 |
| RAI14 | retinoic acid induced 14 | -0.0557775 |
| ERBIN | erbb2 interacting protein | -0.0547855 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -0.0530445 |
| RPL35A | ribosomal protein L35a | -0.0526695 |
| DTNA | dystrobrevin, alpha | -0.0526569 |
| ASPH | aspartate beta-hydroxylase | -0.052508 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0522013 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0513744 |
| FOSL1 | FOS-like antigen 1 | -0.0505313 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0498074 |
| TXNRD1 | thioredoxin reductase 1 | -0.0497915 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0495623 |
| MAP4 | microtubule-associated protein 4 | -0.0490631 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0473357 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0469951 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0468195 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0465636 |
| MT1X | metallothionein 1X | -0.045561 |
| ZNF432 | zinc finger protein 432 | -0.0454446 |
| MMP12 | matrix metallopeptidase 12 | -0.0421439 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0413104 |
| OSMR | oncostatin M receptor | -0.0410818 |
| GOLGA4 | golgin A4 | -0.0407657 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0405116 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0402339 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0400193 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | -0.0394045 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0388912 |
| PTK2 | protein tyrosine kinase 2 | -0.0385383 |
| DST | dystonin | -0.0382285 |
| MAP1B | microtubule-associated protein 1B | -0.0377786 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.0369576 |
| PTBP3 | polypyrimidine tract binding protein 3 | -0.0366491 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0353555 |
| PFN1 | profilin 1 | -0.0351028 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | -0.0346166 |
| NAV1 | neuron navigator 1 | -0.0345236 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0345121 |
| CENPF | centromere protein F, 350/400kDa | -0.0339755 |
| LDHA | lactate dehydrogenase A | -0.0329532 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | -0.0328924 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0326662 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0326233 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0324682 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0322786 |
| STK4 | serine/threonine kinase 4 | -0.0318265 |
| CCND1 | cyclin D1 | -0.0316376 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.0313805 |
| RHOBTB3 | Rho-related BTB domain containing 3 | -0.0310138 |
| VIM | vimentin | -0.0309361 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | -0.0309008 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0301433 |
| S100A10 | S100 calcium binding protein A10 | -0.0299187 |
| ITCH | itchy E3 ubiquitin protein ligase | -0.0295637 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0295507 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0295337 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -0.029405 |
| RTN4 | reticulon 4 | -0.0289915 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0288357 |
| WNT5B | wingless-type MMTV integration site family, member 5B | -0.028069 |
| PKM | pyruvate kinase, muscle | -0.0279099 |
| NAV2 | neuron navigator 2 | -0.0278486 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0277947 |
| HPS3 | Hermansky-Pudlak syndrome 3 | -0.027362 |
| EGFR | epidermal growth factor receptor | -0.0269929 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | -0.0268883 |
| S100A6 | S100 calcium binding protein A6 | -0.0268419 |
| TPM1 | tropomyosin 1 (alpha) | -0.0263512 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0263496 |
| DIAPH3 | diaphanous-related formin 3 | -0.0261453 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0260047 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | -0.0258075 |
| NF1 | neurofibromin 1 | -0.0257267 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0256445 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0254849 |
| PODXL | podocalyxin-like | -0.0254569 |
