| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Crizotinib (hydrochloride) perturbation in LOX-IMVI cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Crizotinib (hydrochloride)_LOX-IMVI drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.066406 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0637498 |
| VIM | vimentin | 0.0629942 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0574532 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0566853 |
| FLNA | filamin A, alpha | 0.053695 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0490673 |
| VCL | vinculin | 0.043907 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0431627 |
| HDAC9 | histone deacetylase 9 | 0.0403757 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0380378 |
| MSN | moesin | 0.0366368 |
| TXNRD1 | thioredoxin reductase 1 | 0.0364506 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0359109 |
| JMJD1C | jumonji domain containing 1C | 0.0340174 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0328421 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.0316451 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0306827 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0297649 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0288645 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.0288581 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0285724 |
| MARCHF4 | membrane associated ring-CH-type finger 4 | 0.0280522 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0277906 |
| MCL1 | myeloid cell leukemia 1 | 0.027278 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0268411 |
| FRMD6 | FERM domain containing 6 | 0.0257983 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0255568 |
| DDAH1 | dimethylarginine dimethylaminohydrolase 1 | 0.025458 |
| YES1 | YES proto-oncogene 1, Src family tyrosine kinase | 0.0253881 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0250061 |
| ARGLU1 | arginine and glutamate rich 1 | 0.0245388 |
| LIMA1 | LIM domain and actin binding 1 | 0.0236871 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0231632 |
| ANKRD28 | ankyrin repeat domain 28 | 0.0229879 |
| CD163L1 | CD163 molecule-like 1 | 0.0229612 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0228869 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0227509 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.0226438 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0221923 |
| ASPH | aspartate beta-hydroxylase | 0.0212898 |
| NAV3 | neuron navigator 3 | 0.0211385 |
| HP1BP3 | heterochromatin protein 1, binding protein 3 | 0.0207014 |
| KISS1 | KiSS-1 metastasis-suppressor | 0.0206386 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0204722 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.020429 |
| RPL4 | ribosomal protein L4 | 0.0203263 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0197881 |
| HMGA2 | high mobility group AT-hook 2 | 0.019726 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | 0.0190288 |
| PLEC | plectin | 0.018612 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.0185509 |
| SPRED1 | sprouty-related, EVH1 domain containing 1 | 0.018005 |
| NPC1 | Niemann-Pick disease, type C1 | 0.0175703 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0172045 |
| CALD1 | caldesmon 1 | 0.0171939 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0170414 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0167975 |
| PRRC2B | proline-rich coiled-coil 2B | 0.016725 |
| CORO1C | coronin, actin binding protein, 1C | 0.0164816 |
| MOK | MOK protein kinase | 0.0158775 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0158345 |
| RPL7 | ribosomal protein L7 | 0.0157775 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | 0.0157444 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0156524 |
| SLC20A2 | solute carrier family 20 (phosphate transporter), member 2 | 0.0155661 |
| TLE4 | transducin-like enhancer of split 4 | 0.0153527 |
| ACTR3 | ARP3 actin-related protein 3 homolog (yeast) | 0.0152846 |
| CDK17 | cyclin-dependent kinase 17 | 0.0151836 |
| DGKD | diacylglycerol kinase, delta 130kDa | 0.0150916 |
| TRIM44 | tripartite motif containing 44 | 0.0150605 |
| BRD2 | bromodomain containing 2 | 0.0150046 |
| HAS2 | hyaluronan synthase 2 | 0.0147616 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0142563 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0142042 |
| SERINC1 | serine incorporator 1 | 0.0141932 |
| RTN4 | reticulon 4 | 0.0141629 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0141124 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.0140603 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0139147 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0138618 |
| MCTP1 | multiple C2 domains, transmembrane 1 | 0.0138456 |
| NACA | nascent polypeptide-associated complex alpha subunit | 0.01365 |
| CASP4 | caspase 4, apoptosis-related cysteine peptidase | 0.0135317 |
| ADAM19 | ADAM metallopeptidase domain 19 | 0.0133685 |
| TOP1 | topoisomerase (DNA) I | 0.0133057 |
| TPM3 | tropomyosin 3 | 0.0132844 |
| EPB41L2 | erythrocyte membrane protein band 4.1-like 2 | 0.0130897 |
| ACTN1 | actinin, alpha 1 | 0.0128701 |
| RPS18 | ribosomal protein S18 | 0.0128679 |
| GDI2 | GDP dissociation inhibitor 2 | 0.0124784 |
| RAB7A | RAB7A, member RAS oncogene family | 0.012447 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0123757 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0118296 |
| RPL3 | ribosomal protein L3 | 0.0118244 |
| PLS3 | plastin 3 | 0.0116784 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0116469 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0116344 |
| AATF | apoptosis antagonizing transcription factor | 0.0115266 |
| SH3RF1 | SH3 domain containing ring finger 1 | 0.0114227 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.258719 |
| TMSB10 | thymosin beta 10 | -0.0925805 |
| ACTG1 | actin gamma 1 | -0.0914627 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0903706 |
| SLC8A1 | solute carrier family 8 (sodium/calcium exchanger), member 1 | -0.0659832 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0602806 |
| FTL | ferritin, light polypeptide | -0.0566887 |
| GPC6 | glypican 6 | -0.0508343 |
| PTK2 | protein tyrosine kinase 2 | -0.0505166 |
| PTMA | prothymosin, alpha | -0.0487551 |
| NDRG1 | N-myc downstream regulated 1 | -0.0467761 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | -0.046386 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0450839 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0432718 |
| RPS6 | ribosomal protein S6 | -0.039971 |
| EGR1 | early growth response 1 | -0.0378101 |
| FOXP1 | forkhead box P1 | -0.0368554 |
| PRKG1 | protein kinase, cGMP-dependent, type I | -0.0361269 |
| PARD3 | par-3 family cell polarity regulator | -0.0353283 |
| RPL35A | ribosomal protein L35a | -0.0350658 |
| RPLP1 | ribosomal protein, large, P1 | -0.0346035 |
| CDH13 | cadherin 13 | -0.0338321 |
| SDCCAG8 | serologically defined colon cancer antigen 8 | -0.033697 |
| ANXA2 | annexin A2 | -0.0328008 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0321636 |
| MT2A | metallothionein 2A | -0.0321448 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0320204 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0307746 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0306526 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0303199 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0300254 |
| ZNF292 | zinc finger protein 292 | -0.0300123 |
| KIAA1549L | KIAA1549-like | -0.0298153 |
| RPS19 | ribosomal protein S19 | -0.0290859 |
| PBX3 | pre-B-cell leukemia homeobox 3 | -0.028479 |
| PHACTR1 | phosphatase and actin regulator 1 | -0.0278987 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0273194 |
| RPS8 | ribosomal protein S8 | -0.0270038 |
| NAV1 | neuron navigator 1 | -0.0268092 |
| GNAS | GNAS complex locus | -0.0252938 |
| RPS25 | ribosomal protein S25 | -0.0247045 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0245406 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0241931 |
| RPL34 | ribosomal protein L34 | -0.0241684 |
| RPL36 | ribosomal protein L36 | -0.0229675 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0229331 |
| MAP4K5 | mitogen-activated protein kinase kinase kinase kinase 5 | -0.0228761 |
| SAMD3 | sterile alpha motif domain containing 3 | -0.0227416 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.022684 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0226281 |
| NTM | neurotrimin | -0.0222183 |
| TRPS1 | trichorhinophalangeal syndrome I | -0.0221339 |
| RPL12 | ribosomal protein L12 | -0.0217709 |
| RPS20 | ribosomal protein S20 | -0.0217187 |
| RIGI | RNA sensor RIG-I | -0.0216152 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0214884 |
| RPL37A | ribosomal protein L37a | -0.0213669 |
| IER3 | immediate early response 3 | -0.0212676 |
| POTEF | POTE ankyrin domain family, member F | -0.0211821 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) | -0.0208656 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0207948 |
| FNDC3B | fibronectin type III domain containing 3B | -0.020727 |
| RPL28 | ribosomal protein L28 | -0.0206379 |
| SSH2 | slingshot protein phosphatase 2 | -0.0206111 |
| RPL32 | ribosomal protein L32 | -0.0203131 |
| RPL5 | ribosomal protein L5 | -0.0201448 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0200101 |
| MAP4 | microtubule-associated protein 4 | -0.0199594 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0198236 |
| TMPRSS15 | transmembrane protease, serine 15 | -0.0197689 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0197113 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0197052 |
| RPS24 | ribosomal protein S24 | -0.0196791 |
| RPLP2 | ribosomal protein, large, P2 | -0.0187688 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0187588 |
| EFNA5 | ephrin-A5 | -0.0187171 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0185311 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0180819 |
| RPL23 | ribosomal protein L23 | -0.017743 |
| RUNX1 | runt-related transcription factor 1 | -0.0175657 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.017536 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | -0.0172555 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0171098 |
| AHNAK | AHNAK nucleoprotein | -0.0170686 |
| RPS13 | ribosomal protein S13 | -0.0170199 |
| HMGA1 | high mobility group AT-hook 1 | -0.0169149 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0166582 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0165629 |
| RPS21 | ribosomal protein S21 | -0.0165209 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0162955 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0162156 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0162137 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0161934 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0161422 |
| RYBP | RING1 and YY1 binding protein | -0.015912 |
| ATXN1 | ataxin 1 | -0.0158582 |
| RACK1 | receptor for activated C kinase 1 | -0.0158013 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0157318 |
| RAD51B | RAD51 paralog B | -0.0157243 |
| EXOC4 | exocyst complex component 4 | -0.0156617 |
