| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Crizotinib (hydrochloride) perturbation in MIA PaCa-2 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Crizotinib (hydrochloride)_MIA PaCa-2 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CANX | calnexin | 0.0695986 |
| VIM | vimentin | 0.0616782 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0452789 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0422604 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.041427 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0408001 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0379638 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0372634 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0346611 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.0344394 |
| TMSB4X | thymosin beta 4, X-linked | 0.0339013 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0325196 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0324798 |
| APP | amyloid beta (A4) precursor protein | 0.0293113 |
| CALR | calreticulin | 0.0286879 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.0283857 |
| SET | SET nuclear proto-oncogene | 0.0270252 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0270174 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0265714 |
| KRT18 | keratin 18, type I | 0.0246518 |
| DST | dystonin | 0.0244806 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.023869 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0230241 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0222555 |
| ZDHHC14 | zinc finger, DHHC-type containing 14 | 0.022011 |
| CLIP2 | CAP-GLY domain containing linker protein 2 | 0.0216212 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0215275 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0213178 |
| ARHGEF2 | Rho/Rac guanine nucleotide exchange factor (GEF) 2 | 0.021218 |
| TFRC | transferrin receptor | 0.0208709 |
| EFNA5 | ephrin-A5 | 0.0205205 |
| PTPRF | protein tyrosine phosphatase, receptor type, F | 0.0203931 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0193621 |
| HDGF | hepatoma-derived growth factor | 0.0189591 |
| FLNA | filamin A, alpha | 0.0188692 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0188328 |
| TNS3 | tensin 3 | 0.0188194 |
| PLK2 | polo-like kinase 2 | 0.0187695 |
| FMNL2 | formin-like 2 | 0.0187224 |
| CEP250 | centrosomal protein 250kDa | 0.0184832 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | 0.0183871 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0183585 |
| MCL1 | myeloid cell leukemia 1 | 0.018038 |
| WDR43 | WD repeat domain 43 | 0.0180158 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.017999 |
| HDAC9 | histone deacetylase 9 | 0.0178447 |
| ARRDC3 | arrestin domain containing 3 | 0.0175828 |
| VEGFA | vascular endothelial growth factor A | 0.017385 |
| SMAD3 | SMAD family member 3 | 0.01718 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0169619 |
| KDM4B | lysine (K)-specific demethylase 4B | 0.0168723 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.016672 |
| MYOF | myoferlin | 0.0166395 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0164991 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.0164821 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0162041 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0159863 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0159051 |
| PLEC | plectin | 0.0158714 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | 0.0158042 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | 0.0156058 |
| EPHA4 | EPH receptor A4 | 0.0154761 |
| CMIP | c-Maf inducing protein | 0.0151968 |
| ITPR3 | inositol 1,4,5-trisphosphate receptor, type 3 | 0.0149668 |
| BRD2 | bromodomain containing 2 | 0.0148056 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | 0.0146844 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0146247 |
| TPM3 | tropomyosin 3 | 0.0145591 |
| RPL3 | ribosomal protein L3 | 0.0145338 |
| RPL4 | ribosomal protein L4 | 0.0141713 |
| DDX3X | DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked | 0.014149 |
| SERINC1 | serine incorporator 1 | 0.0141253 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.0140561 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0137074 |
| EIF3B | eukaryotic translation initiation factor 3, subunit B | 0.0134886 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0134413 |
| SYNCRIP | synaptotagmin binding, cytoplasmic RNA interacting protein | 0.0133969 |
| AARS1 | alanyl-tRNA synthetase 1 | 0.0133632 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0133428 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0132878 |
| SUPT5H | suppressor of Ty 5 homolog (S. cerevisiae) | 0.0131453 |
| YEATS2 | YEATS domain containing 2 | 0.0131104 |
| DENND5A | DENN/MADD domain containing 5A | 0.0130097 |
| YME1L1 | YME1-like 1 ATPase | 0.0129793 |
| PDIA4 | protein disulfide isomerase family A, member 4 | 0.0129761 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.0129661 |
| PNN | pinin, desmosome associated protein | 0.0129498 |
| DIP2C | DIP2 disco-interacting protein 2 homolog C (Drosophila) | 0.0128395 |
| ZNF146 | zinc finger protein 146 | 0.0127395 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0127332 |
| FNBP4 | formin binding protein 4 | 0.0126869 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0126476 |
| CTBP2 | C-terminal binding protein 2 | 0.0126097 |
| GYS1 | glycogen synthase 1 (muscle) | 0.0123216 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0121718 |
| ARGLU1 | arginine and glutamate rich 1 | 0.0121117 |
| PPFIA4 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4 | 0.0120659 |
| BEGAIN | brain-enriched guanylate kinase-associated | 0.0120589 |
| FAM168A | family with sequence similarity 168, member A | 0.0118922 |
| KIF1B | kinesin family member 1B | 0.0117803 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.571449 |
| MT2A | metallothionein 2A | -0.311045 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.106512 |
| TMSB10 | thymosin beta 10 | -0.105236 |
| ACTG1 | actin gamma 1 | -0.0871932 |
| MT1X | metallothionein 1X | -0.086289 |
| MT1E | metallothionein 1E | -0.0739775 |
| RPL35A | ribosomal protein L35a | -0.0707434 |
| FTL | ferritin, light polypeptide | -0.0561808 |
| RPS6 | ribosomal protein S6 | -0.0548775 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0522907 |
| TXNRD1 | thioredoxin reductase 1 | -0.0516932 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0503782 |
| POTEF | POTE ankyrin domain family, member F | -0.0438622 |
| GCLM | glutamate-cysteine ligase, modifier subunit | -0.0428051 |
| RPL12 | ribosomal protein L12 | -0.0424909 |
| RPS8 | ribosomal protein S8 | -0.0420326 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0419748 |
| EGR1 | early growth response 1 | -0.0408207 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0396215 |
| RPLP1 | ribosomal protein, large, P1 | -0.0384306 |
| RPLP0 | ribosomal protein, large, P0 | -0.038168 |
| RPS19 | ribosomal protein S19 | -0.0379343 |
| S100A10 | S100 calcium binding protein A10 | -0.0373596 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0347242 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | -0.0342925 |
| SRGN | serglycin | -0.0339777 |
| RPS23 | ribosomal protein S23 | -0.0328269 |
| RPL5 | ribosomal protein L5 | -0.0323465 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.031191 |
| TXNIP | thioredoxin interacting protein | -0.0310703 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0308701 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0307723 |
| S100A6 | S100 calcium binding protein A6 | -0.0304432 |
| RPLP2 | ribosomal protein, large, P2 | -0.0302583 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0295743 |
| HMGA1 | high mobility group AT-hook 1 | -0.0294858 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0291692 |
| S100A9 | S100 calcium binding protein A9 | -0.0291233 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0282099 |
| SLC20A1 | solute carrier family 20 (phosphate transporter), member 1 | -0.0278725 |
| RPL28 | ribosomal protein L28 | -0.0273262 |
| RPL8 | ribosomal protein L8 | -0.0271706 |
| RPL34 | ribosomal protein L34 | -0.0268637 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0268194 |
| RTN4 | reticulon 4 | -0.0263055 |
| TNFRSF6B | tumor necrosis factor receptor superfamily, member 6b, decoy | -0.0262729 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0261496 |
| EMP1 | epithelial membrane protein 1 | -0.0260546 |
| RPS15 | ribosomal protein S15 | -0.0258895 |
| SPRY4 | sprouty homolog 4 (Drosophila) | -0.0257113 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0255495 |
| RPL36 | ribosomal protein L36 | -0.0254861 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.0252397 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | -0.025023 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0244194 |
| RPS21 | ribosomal protein S21 | -0.0242783 |
| RPL26 | ribosomal protein L26 | -0.0240292 |
| ENO1 | enolase 1, (alpha) | -0.023794 |
| RPL32 | ribosomal protein L32 | -0.0237216 |
| PRDX1 | peroxiredoxin 1 | -0.0236389 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0235961 |
| TPI1 | triosephosphate isomerase 1 | -0.0233852 |
| FOSL1 | FOS-like antigen 1 | -0.0231154 |
| RAI1 | retinoic acid induced 1 | -0.0227646 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0225334 |
| RPS29 | ribosomal protein S29 | -0.0224396 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.0222423 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.022005 |
| RPL35 | ribosomal protein L35 | -0.0218631 |
| PFN1 | profilin 1 | -0.0217088 |
| RACK1 | receptor for activated C kinase 1 | -0.0216432 |
| CD44 | CD44 molecule (Indian blood group) | -0.0215699 |
| SEPTIN7 | septin 7 | -0.0215069 |
| RPL31 | ribosomal protein L31 | -0.0213156 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | -0.0213086 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | -0.020557 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0204294 |
| RPS13 | ribosomal protein S13 | -0.0202759 |
| ANGPTL4 | angiopoietin-like 4 | -0.0201689 |
| RPS14 | ribosomal protein S14 | -0.0198251 |
| RPS5 | ribosomal protein S5 | -0.0198101 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0197843 |
| RPL9 | ribosomal protein L9 | -0.0197003 |
| TP63 | tumor protein p63 | -0.0195537 |
| FBXO11 | F-box protein 11 | -0.0194257 |
| RPS24 | ribosomal protein S24 | -0.0193357 |
| TMEM41B | transmembrane protein 41B | -0.0190471 |
| BPTF | bromodomain PHD finger transcription factor | -0.0186326 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0185635 |
| RPS16 | ribosomal protein S16 | -0.0185194 |
| ERCC1 | excision repair cross-complementation group 1 | -0.0184467 |
| USP34 | ubiquitin specific peptidase 34 | -0.0183232 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0178349 |
| CAPZA1 | capping protein (actin filament) muscle Z-line, alpha 1 | -0.0175954 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.017554 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0175076 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | -0.0174287 |
| CENPF | centromere protein F, 350/400kDa | -0.017333 |
| CBX3 | chromobox homolog 3 | -0.0172169 |
