| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Crizotinib (hydrochloride) perturbation in NCI-H1573 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Crizotinib (hydrochloride)_NCI-H1573 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0719083 |
| ARGLU1 | arginine and glutamate rich 1 | 0.0684241 |
| RPS3 | ribosomal protein S3 | 0.0669935 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0633631 |
| CANX | calnexin | 0.0573824 |
| PLEC | plectin | 0.0550243 |
| RPL7 | ribosomal protein L7 | 0.0523174 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0519161 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0519101 |
| LAMC2 | laminin, gamma 2 | 0.0490947 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0490086 |
| LAMB3 | laminin, beta 3 | 0.0442579 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.042577 |
| ARRDC3 | arrestin domain containing 3 | 0.0419207 |
| HYOU1 | hypoxia up-regulated 1 | 0.0412101 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0389084 |
| MKI67 | marker of proliferation Ki-67 | 0.0388868 |
| RPL4 | ribosomal protein L4 | 0.0384844 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0372775 |
| KRT18 | keratin 18, type I | 0.0363404 |
| CES1 | carboxylesterase 1 | 0.0363157 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0356998 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0351306 |
| TES | testin LIM domain protein | 0.034819 |
| ADAR | adenosine deaminase, RNA-specific | 0.0344573 |
| RPS4X | ribosomal protein S4, X-linked | 0.0331242 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0327597 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0321833 |
| MCL1 | myeloid cell leukemia 1 | 0.0320966 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0307037 |
| RNF213 | ring finger protein 213 | 0.0304636 |
| NDE1 | nudE neurodevelopment protein 1 | 0.0303252 |
| TBC1D22A | TBC1 domain family, member 22A | 0.0300265 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.029208 |
| ZC3H11A | zinc finger CCCH-type containing 11A | 0.0290488 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0287029 |
| PGK1 | phosphoglycerate kinase 1 | 0.0286513 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0275184 |
| ACIN1 | apoptotic chromatin condensation inducer 1 | 0.0271747 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.027033 |
| DDX3X | DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked | 0.0266033 |
| RPL11 | ribosomal protein L11 | 0.0261732 |
| RPL13A | ribosomal protein L13a | 0.025695 |
| SRSF5 | serine/arginine-rich splicing factor 5 | 0.0254615 |
| MCTP1 | multiple C2 domains, transmembrane 1 | 0.0253936 |
| TUFT1 | tuftelin 1 | 0.0247681 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0247062 |
| DSPP | dentin sialophosphoprotein | 0.0240719 |
| PDIA4 | protein disulfide isomerase family A, member 4 | 0.0240291 |
| TXNRD1 | thioredoxin reductase 1 | 0.0236611 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0236578 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0235963 |
| RSL1D1 | ribosomal L1 domain containing 1 | 0.0235726 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0233113 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.0232308 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.023074 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0226324 |
| FZR1 | fizzy/cell division cycle 20 related 1 (Drosophila) | 0.0223406 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0215242 |
| ATF4 | activating transcription factor 4 | 0.020779 |
| UBC | ubiquitin C | 0.0206396 |
| SF3B2 | splicing factor 3b, subunit 2, 145kDa | 0.0205627 |
| NSUN6 | NOP2/Sun domain family, member 6 | 0.0202412 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | 0.0199159 |
| TMCO3 | transmembrane and coiled-coil domains 3 | 0.019875 |
| TMF1 | TATA element modulatory factor 1 | 0.0198323 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0196144 |
| CDPF1 | cysteine-rich, DPF motif domain containing 1 | 0.0193782 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0193201 |
| RAD21 | RAD21 homolog (S. pombe) | 0.0192827 |
| BTAF1 | BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa | 0.0191887 |
| NR4A3 | nuclear receptor subfamily 4, group A, member 3 | 0.0191393 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0190458 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0187519 |
| SUPT6H | suppressor of Ty 6 homolog (S. cerevisiae) | 0.0186282 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.0185416 |
| SPAG9 | sperm associated antigen 9 | 0.0185384 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | 0.0184185 |
| SMG7 | SMG7 nonsense mediated mRNA decay factor | 0.0181347 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0180393 |
| B2M | beta-2-microglobulin | 0.0180337 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0178789 |
| CALR | calreticulin | 0.0176872 |
| PTMA | prothymosin, alpha | 0.0176626 |
| PNN | pinin, desmosome associated protein | 0.0173597 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 | 0.0173467 |
| PPFIA1 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 | 0.0173439 |
| SERINC1 | serine incorporator 1 | 0.0173213 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | 0.0172685 |
| HNRNPR | heterogeneous nuclear ribonucleoprotein R | 0.017224 |
| IST1 | increased sodium tolerance 1 homolog (yeast) | 0.0171125 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.0170834 |
| HDLBP | high density lipoprotein binding protein | 0.0170564 |
| GSK3B | glycogen synthase kinase 3 beta | 0.0169916 |
| DCUN1D3 | DCN1, defective in cullin neddylation 1, domain containing 3 | 0.0169387 |
| ARL5B | ADP-ribosylation factor-like 5B | 0.0168194 |
| F11R | F11 receptor | 0.0166775 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0166575 |
| VCL | vinculin | 0.0166497 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | 0.0163541 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.549292 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.195871 |
| NDRG1 | N-myc downstream regulated 1 | -0.148431 |
| EGFR | epidermal growth factor receptor | -0.139124 |
| EGR1 | early growth response 1 | -0.0861576 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0821121 |
| ACTG1 | actin gamma 1 | -0.0770882 |
| TMSB10 | thymosin beta 10 | -0.0737226 |
| SEC61G | Sec61 gamma subunit | -0.0681685 |
| S100A10 | S100 calcium binding protein A10 | -0.0673827 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0597716 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0577408 |
| LMO7 | LIM domain 7 | -0.0539558 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0519707 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0464635 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0458488 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | -0.0448039 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | -0.0425907 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | -0.0415195 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0409652 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0408005 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0403951 |
| POTEF | POTE ankyrin domain family, member F | -0.0400631 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0400452 |
| ANKRD12 | ankyrin repeat domain 12 | -0.039956 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0398076 |
| FAM13A | family with sequence similarity 13, member A | -0.0383913 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0382512 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.0379516 |
| WASF2 | WAS protein family, member 2 | -0.0378846 |
| RPL35A | ribosomal protein L35a | -0.0378058 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0373895 |
| PARD3 | par-3 family cell polarity regulator | -0.0373665 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0373225 |
| CAV2 | caveolin 2 | -0.0359087 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0345871 |
| PDE8A | phosphodiesterase 8A | -0.0344509 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0344225 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0337227 |
| DOCK5 | dedicator of cytokinesis 5 | -0.0331392 |
| BPTF | bromodomain PHD finger transcription factor | -0.0313391 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0309965 |
| MARK3 | MAP/microtubule affinity-regulating kinase 3 | -0.0307005 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0303356 |
| RPLP1 | ribosomal protein, large, P1 | -0.0297211 |
| SCEL | sciellin | -0.0294713 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0290675 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0290019 |
| STC1 | stanniocalcin 1 | -0.0286661 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0282708 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.0282313 |
| OSMR | oncostatin M receptor | -0.027927 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | -0.0279001 |
| ZNF638 | zinc finger protein 638 | -0.0278052 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0275636 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0273825 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0272024 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0271002 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0266453 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0264261 |
| CST3 | cystatin C | -0.0263192 |
| HMGA1 | high mobility group AT-hook 1 | -0.0260442 |
| TJP1 | tight junction protein 1 | -0.0259631 |
| CDCP1 | CUB domain containing protein 1 | -0.0248663 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0242668 |
| ROCK1 | Rho-associated, coiled-coil containing protein kinase 1 | -0.0242237 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | -0.0238778 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0233316 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0227774 |
| MORF4L2 | mortality factor 4 like 2 | -0.0227484 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0225745 |
| FOXP1 | forkhead box P1 | -0.022355 |
| PFN1 | profilin 1 | -0.0222843 |
| NFKB1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 | -0.022174 |
| PKM | pyruvate kinase, muscle | -0.0220334 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0220286 |
| IER3 | immediate early response 3 | -0.0218214 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0216189 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0215377 |
| ANKRD37 | ankyrin repeat domain 37 | -0.0213876 |
| CDK2AP2 | cyclin-dependent kinase 2 associated protein 2 | -0.0213767 |
| RAP1B | RAP1B, member of RAS oncogene family | -0.0213707 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0212586 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0212127 |
| EFNA5 | ephrin-A5 | -0.0211608 |
| MED13L | mediator complex subunit 13-like | -0.0210893 |
| JMJD1C | jumonji domain containing 1C | -0.0210794 |
| RASA2 | RAS p21 protein activator 2 | -0.0210302 |
| FBXO11 | F-box protein 11 | -0.0207547 |
| PACS1 | phosphofurin acidic cluster sorting protein 1 | -0.0206637 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0204206 |
| PTK2 | protein tyrosine kinase 2 | -0.0200273 |
| SLC38A2 | solute carrier family 38, member 2 | -0.019949 |
| S100A9 | S100 calcium binding protein A9 | -0.0194321 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.0193093 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0191259 |
| RAPGEF2 | Rap guanine nucleotide exchange factor (GEF) 2 | -0.0191134 |
| UPP1 | uridine phosphorylase 1 | -0.0190122 |
| RIN2 | Ras and Rab interactor 2 | -0.0188926 |
| BRWD1 | bromodomain and WD repeat domain containing 1 | -0.0188337 |
