| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Crizotinib (hydrochloride) perturbation in NCI-H1792 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Crizotinib (hydrochloride)_NCI-H1792 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.192016 |
| VIM | vimentin | 0.119309 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.097348 |
| SMAD3 | SMAD family member 3 | 0.0855277 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.080489 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0788411 |
| PCBP2 | poly(rC) binding protein 2 | 0.0774637 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0688545 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0649959 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.064683 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0644501 |
| OS9 | osteosarcoma amplified 9, endoplasmic reticulum lectin | 0.0615393 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.060703 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0604464 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0546537 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0540644 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0532088 |
| OGA | O-GlcNAcase | 0.0531368 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0515969 |
| NAV2 | neuron navigator 2 | 0.051381 |
| FAM107B | family with sequence similarity 107, member B | 0.0506626 |
| FAM13A | family with sequence similarity 13, member A | 0.0486203 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0484699 |
| FLNB | filamin B, beta | 0.0464822 |
| ADD3 | adducin 3 (gamma) | 0.0448317 |
| CANX | calnexin | 0.0443423 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.043593 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0408701 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0406684 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0392944 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0392655 |
| GOLGA4 | golgin A4 | 0.0392239 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0389866 |
| APP | amyloid beta (A4) precursor protein | 0.0387324 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0384868 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0382863 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0370419 |
| CEP250 | centrosomal protein 250kDa | 0.0363455 |
| SPAG9 | sperm associated antigen 9 | 0.0361432 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0359767 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.035809 |
| RIOK3 | RIO kinase 3 | 0.0348046 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.033785 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0331965 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0331193 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0326755 |
| VEGFA | vascular endothelial growth factor A | 0.0325523 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0323575 |
| PDK3 | pyruvate dehydrogenase kinase, isozyme 3 | 0.0323498 |
| YME1L1 | YME1-like 1 ATPase | 0.0321043 |
| MSN | moesin | 0.0320834 |
| RAB8B | RAB8B, member RAS oncogene family | 0.0319734 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.0315071 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0314968 |
| CAB39 | calcium binding protein 39 | 0.0314942 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0314434 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0314398 |
| OTUD7B | OTU deubiquitinase 7B | 0.0304313 |
| PDIA4 | protein disulfide isomerase family A, member 4 | 0.0296941 |
| AHR | aryl hydrocarbon receptor | 0.029669 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0296228 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | 0.0292836 |
| XPO1 | exportin 1 | 0.0291322 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 | 0.0290458 |
| ARRDC3 | arrestin domain containing 3 | 0.0289262 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0288296 |
| COPA | coatomer protein complex, subunit alpha | 0.028771 |
| SIK3 | SIK family kinase 3 | 0.0286742 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0285248 |
| FMNL2 | formin-like 2 | 0.0283489 |
| AMPD3 | adenosine monophosphate deaminase 3 | 0.0279631 |
| FLNA | filamin A, alpha | 0.0274745 |
| JMJD1C | jumonji domain containing 1C | 0.0274486 |
| SETD5 | SET domain containing 5 | 0.027378 |
| CNOT12 | CCR4-NOT transcription complex subunit 12 | 0.0271555 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | 0.0271159 |
| OPTN | optineurin | 0.0270715 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | 0.0266922 |
| EIF3B | eukaryotic translation initiation factor 3, subunit B | 0.0264312 |
| FOXO3 | forkhead box O3 | 0.0264024 |
| SERINC1 | serine incorporator 1 | 0.02639 |
| SEC23A | Sec23 homolog A (S. cerevisiae) | 0.0261095 |
| KLF6 | Kruppel-like factor 6 | 0.0258115 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.0255224 |
| ZNRF1 | zinc and ring finger 1, E3 ubiquitin protein ligase | 0.025297 |
| USP3 | ubiquitin specific peptidase 3 | 0.0251896 |
| EZR | ezrin | 0.0251797 |
| RUNX1 | runt-related transcription factor 1 | 0.0249995 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.0249292 |
| SRP54 | signal recognition particle 54kDa | 0.0245986 |
| DPYSL3 | dihydropyrimidinase-like 3 | 0.0242599 |
| HELZ | helicase with zinc finger | 0.0240157 |
| ATP13A3 | ATPase type 13A3 | 0.0238286 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.0236812 |
| YEATS2 | YEATS domain containing 2 | 0.023029 |
| YTHDC1 | YTH domain containing 1 | 0.0229564 |
| SUCO | SUN domain containing ossification factor | 0.0228391 |
| MAP2K1 | mitogen-activated protein kinase kinase 1 | 0.0228384 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0227439 |
| ANXA1 | annexin A1 | 0.0226497 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.197198 |
| TMSB10 | thymosin beta 10 | -0.131229 |
| LOX | lysyl oxidase | -0.122149 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.122027 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0789919 |
| CDH13 | cadherin 13 | -0.0755121 |
| NRG1 | neuregulin 1 | -0.0750098 |
| CD44 | CD44 molecule (Indian blood group) | -0.0739682 |
| RPL35A | ribosomal protein L35a | -0.0705134 |
| HMGA2 | high mobility group AT-hook 2 | -0.0669254 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0641594 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0611537 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0602924 |
| OSMR | oncostatin M receptor | -0.0595234 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | -0.0583804 |
| EGR1 | early growth response 1 | -0.0559911 |
| FTL | ferritin, light polypeptide | -0.0553715 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.0539469 |
| GPC6 | glypican 6 | -0.0521059 |
| STC1 | stanniocalcin 1 | -0.0493381 |
| RPL31 | ribosomal protein L31 | -0.0449516 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | -0.0443468 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0442389 |
| IER3 | immediate early response 3 | -0.0436975 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0430611 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0421489 |
| SYT1 | synaptotagmin I | -0.0414176 |
| FAM20C | family with sequence similarity 20, member C | -0.0401614 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0395608 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0394775 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | -0.0393058 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0391567 |
| ZNF804A | zinc finger protein 804A | -0.0387709 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0382486 |
| RPL37A | ribosomal protein L37a | -0.0378137 |
| RPLP1 | ribosomal protein, large, P1 | -0.037556 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | -0.0368352 |
| LRMDA | leucine rich melanocyte differentiation associated | -0.036677 |
| HLA-B | major histocompatibility complex, class I, B | -0.0350046 |
| RPS29 | ribosomal protein S29 | -0.034327 |
| CLMP | CXADR-like membrane protein | -0.0342555 |
| GLIS3 | GLIS family zinc finger 3 | -0.0333944 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0332888 |
| DNER | delta/notch-like EGF repeat containing | -0.0324429 |
| NTN4 | netrin 4 | -0.0321921 |
| STXBP5 | syntaxin binding protein 5 (tomosyn) | -0.0321484 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0319015 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0317647 |
| RPL34 | ribosomal protein L34 | -0.031626 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0315171 |
| RPS19 | ribosomal protein S19 | -0.0314742 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0310542 |
| POTEF | POTE ankyrin domain family, member F | -0.0310246 |
| MX2 | MX dynamin-like GTPase 2 | -0.0309177 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0307953 |
| RPS13 | ribosomal protein S13 | -0.0304319 |
| IFI44L | interferon-induced protein 44-like | -0.0302118 |
| RPL28 | ribosomal protein L28 | -0.0297586 |
| GLCCI1 | glucocorticoid induced 1 | -0.0294203 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0293709 |
| RPS8 | ribosomal protein S8 | -0.0292554 |
| RPS25 | ribosomal protein S25 | -0.0289307 |
| FBN1 | fibrillin 1 | -0.0287026 |
| GRIK5 | glutamate receptor, ionotropic, kainate 5 | -0.0286026 |
| CDK14 | cyclin-dependent kinase 14 | -0.0285707 |
| BPTF | bromodomain PHD finger transcription factor | -0.0281102 |
| MSRB3 | methionine sulfoxide reductase B3 | -0.0280623 |
| CLIC4 | chloride intracellular channel 4 | -0.0279198 |
| PRH1 | proline-rich protein HaeIII subfamily 1 | -0.0276724 |
| RPL36 | ribosomal protein L36 | -0.0272869 |
| TNNC1 | troponin C type 1 (slow) | -0.0270712 |
| CUX1 | cut-like homeobox 1 | -0.0268121 |
| PID1 | phosphotyrosine interaction domain containing 1 | -0.0267577 |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog | -0.0266272 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | -0.0263907 |
| EHBP1 | EH domain binding protein 1 | -0.0262423 |
| ATG7 | autophagy related 7 | -0.0262152 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0254945 |
| RPS24 | ribosomal protein S24 | -0.0254441 |
| VRK2 | vaccinia related kinase 2 | -0.0254273 |
| INTS6 | integrator complex subunit 6 | -0.025322 |
| GREB1L | growth regulation by estrogen in breast cancer-like | -0.0252369 |
| SUMF1 | sulfatase modifying factor 1 | -0.0252239 |
| EXOC4 | exocyst complex component 4 | -0.0251573 |
| RPS6 | ribosomal protein S6 | -0.0251316 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.0248147 |
| S100A10 | S100 calcium binding protein A10 | -0.0248 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0247759 |
| SOS1 | son of sevenless homolog 1 (Drosophila) | -0.0246646 |
| ACTG1 | actin gamma 1 | -0.0245683 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0242868 |
| RPLP2 | ribosomal protein, large, P2 | -0.0242655 |
| PNPT1 | polyribonucleotide nucleotidyltransferase 1 | -0.024233 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0241462 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0241007 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0240177 |
| ETV6 | ets variant 6 | -0.0238393 |
| NLK | nemo-like kinase | -0.023817 |
| OXR1 | oxidation resistance 1 | -0.0236018 |
| SP100 | SP100 nuclear antigen | -0.0233399 |
