| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Crizotinib (hydrochloride) perturbation in NCI-H460 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Crizotinib (hydrochloride)_NCI-H460 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | 0.161487 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | 0.0842379 |
| RGS2 | regulator of G-protein signaling 2 | 0.0767574 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0717721 |
| EFNA5 | ephrin-A5 | 0.0656614 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0563901 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0559955 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0539808 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0490468 |
| PGK1 | phosphoglycerate kinase 1 | 0.0480895 |
| GRAMD1B | GRAM domain containing 1B | 0.047263 |
| GDA | guanine deaminase | 0.0462647 |
| VIM | vimentin | 0.0449945 |
| FLNA | filamin A, alpha | 0.0434423 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.0410883 |
| MYOF | myoferlin | 0.040792 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.040067 |
| CANX | calnexin | 0.0395751 |
| TGFBR1 | transforming growth factor, beta receptor 1 | 0.0366609 |
| NRCAM | neuronal cell adhesion molecule | 0.0349558 |
| MCL1 | myeloid cell leukemia 1 | 0.0342267 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0340947 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.03313 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0327893 |
| RAB3B | RAB3B, member RAS oncogene family | 0.0320512 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0316186 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0312156 |
| CTSL | cathepsin L | 0.0306954 |
| COL5A2 | collagen, type V, alpha 2 | 0.0295755 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0293032 |
| APP | amyloid beta (A4) precursor protein | 0.0288459 |
| NEK7 | NIMA-related kinase 7 | 0.0284846 |
| EPB41L3 | erythrocyte membrane protein band 4.1-like 3 | 0.0276799 |
| ASPH | aspartate beta-hydroxylase | 0.0272098 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0270192 |
| FLNB | filamin B, beta | 0.0266326 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0263629 |
| PYGL | phosphorylase, glycogen, liver | 0.0263576 |
| CD109 | CD109 molecule | 0.0252757 |
| ZBTB38 | zinc finger and BTB domain containing 38 | 0.024813 |
| DGKD | diacylglycerol kinase, delta 130kDa | 0.0247814 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0240359 |
| RPS4X | ribosomal protein S4, X-linked | 0.0238943 |
| LAMB1 | laminin, beta 1 | 0.0233785 |
| STC2 | stanniocalcin 2 | 0.0231851 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0229712 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0229361 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0228664 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0225665 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0225095 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | 0.0224229 |
| VCL | vinculin | 0.0220435 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0218791 |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 | 0.0218137 |
| RPL4 | ribosomal protein L4 | 0.0217047 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0216916 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | 0.0209462 |
| COL8A1 | collagen, type VIII, alpha 1 | 0.0197727 |
| CAPN2 | calpain 2, (m/II) large subunit | 0.0197699 |
| TMX4 | thioredoxin-related transmembrane protein 4 | 0.019521 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0194168 |
| BDNF | brain-derived neurotrophic factor | 0.0192337 |
| MSN | moesin | 0.0191745 |
| ABL1 | ABL proto-oncogene 1, non-receptor tyrosine kinase | 0.0190754 |
| ADAR | adenosine deaminase, RNA-specific | 0.0190654 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0189363 |
| PDIA4 | protein disulfide isomerase family A, member 4 | 0.0188875 |
| MKI67 | marker of proliferation Ki-67 | 0.0184456 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | 0.0184388 |
| SLC7A2 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 | 0.0183251 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0182711 |
| SLC2A13 | solute carrier family 2 (facilitated glucose transporter), member 13 | 0.0179227 |
| DDX3X | DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked | 0.0179138 |
| PPFIA4 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4 | 0.0175265 |
| RPL7 | ribosomal protein L7 | 0.0175087 |
| CAB39 | calcium binding protein 39 | 0.017211 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0171496 |
| LAMA1 | laminin, alpha 1 | 0.0169783 |
| CKAP5 | cytoskeleton associated protein 5 | 0.0169738 |
| CEP250 | centrosomal protein 250kDa | 0.016867 |
| PM20D1 | peptidase M20 domain containing 1 | 0.0168212 |
| OS9 | osteosarcoma amplified 9, endoplasmic reticulum lectin | 0.0165441 |
| PCBP3 | poly(rC) binding protein 3 | 0.0163872 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | 0.0160951 |
| BMERB1 | bMERB domain containing 1 | 0.0158743 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0158702 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0158532 |
| BMAL2 | basic helix-loop-helix ARNT like 2 | 0.0157556 |
| GANAB | glucosidase, alpha; neutral AB | 0.0157083 |
| GPRIN3 | GPRIN family member 3 | 0.0156438 |
| CFLAR | CASP8 and FADD-like apoptosis regulator | 0.0155257 |
| IGF1R | insulin-like growth factor 1 receptor | 0.0153448 |
| RPL3 | ribosomal protein L3 | 0.0151889 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0149662 |
| ANO6 | anoctamin 6 | 0.0149258 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0148706 |
| IGF2R | insulin-like growth factor 2 receptor | 0.0148428 |
| SEPTIN10 | septin 10 | 0.0148215 |
| CD274 | CD274 molecule | 0.0147733 |
| ARGLU1 | arginine and glutamate rich 1 | 0.0146134 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.273999 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.185076 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.133837 |
| FTL | ferritin, light polypeptide | -0.101146 |
| TMSB10 | thymosin beta 10 | -0.0933387 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0852564 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0848522 |
| RPS6 | ribosomal protein S6 | -0.0819133 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0781784 |
| RPLP1 | ribosomal protein, large, P1 | -0.0674396 |
| RPL35A | ribosomal protein L35a | -0.0512693 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0471518 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.0470492 |
| SPAG9 | sperm associated antigen 9 | -0.0461822 |
| RPS8 | ribosomal protein S8 | -0.0453285 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0452758 |
| RPS19 | ribosomal protein S19 | -0.0448301 |
| RPL37A | ribosomal protein L37a | -0.0430398 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0420843 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0418925 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | -0.0414538 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0381695 |
| PTMA | prothymosin, alpha | -0.0381365 |
| EGR1 | early growth response 1 | -0.0378321 |
| DPP10 | dipeptidyl-peptidase 10 (non-functional) | -0.0371166 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | -0.0371154 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0368299 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0365873 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0360514 |
| NDRG1 | N-myc downstream regulated 1 | -0.0355638 |
| ACTG1 | actin gamma 1 | -0.034496 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0334828 |
| B2M | beta-2-microglobulin | -0.0334034 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0333544 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0319814 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0317712 |
| RPL36 | ribosomal protein L36 | -0.0314266 |
| RPL34 | ribosomal protein L34 | -0.0308896 |
| RPL28 | ribosomal protein L28 | -0.0302921 |
| IER3 | immediate early response 3 | -0.0302358 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | -0.0297717 |
| POTEF | POTE ankyrin domain family, member F | -0.0291553 |
| NUP58 | nucleoporin 58 | -0.0287709 |
| RPL12 | ribosomal protein L12 | -0.028212 |
| FBXO11 | F-box protein 11 | -0.0280527 |
| WDR45B | WD repeat domain 45B | -0.0278474 |
| S100A10 | S100 calcium binding protein A10 | -0.0275544 |
| MT2A | metallothionein 2A | -0.0274556 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0274262 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0271905 |
| RPL31 | ribosomal protein L31 | -0.02701 |
| RPL26 | ribosomal protein L26 | -0.0269273 |
| PRKN | parkin RBR E3 ubiquitin protein ligase | -0.0269264 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0266165 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0264049 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 | -0.0263344 |
| GNAS | GNAS complex locus | -0.0259208 |
| PFN1 | profilin 1 | -0.0256476 |
| RPS14 | ribosomal protein S14 | -0.0256021 |
| RTN4 | reticulon 4 | -0.0256019 |
| ASTN2 | astrotactin 2 | -0.0255371 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0254549 |
| S100A6 | S100 calcium binding protein A6 | -0.0254211 |
| RPL9 | ribosomal protein L9 | -0.0250917 |
| RPS16 | ribosomal protein S16 | -0.0242702 |
| SQSTM1 | sequestosome 1 | -0.0241114 |
| RBM39 | RNA binding motif protein 39 | -0.0241 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0237871 |
| RPLP2 | ribosomal protein, large, P2 | -0.0236783 |
| RPL5 | ribosomal protein L5 | -0.023645 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0235052 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0234776 |
| RPL37 | ribosomal protein L37 | -0.0232901 |
| RACK1 | receptor for activated C kinase 1 | -0.0231496 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0230305 |
| CHD1 | chromodomain helicase DNA binding protein 1 | -0.0228035 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.022795 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0227861 |
| RPS12 | ribosomal protein S12 | -0.0227671 |
| RPL35 | ribosomal protein L35 | -0.0223094 |
| COL4A5 | collagen, type IV, alpha 5 | -0.0221903 |
| USP3 | ubiquitin specific peptidase 3 | -0.0220821 |
| ATP1B3 | ATPase, Na+/K+ transporting, beta 3 polypeptide | -0.0220278 |
| RPL19 | ribosomal protein L19 | -0.0219903 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | -0.021981 |
| RPS25 | ribosomal protein S25 | -0.0219502 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0216998 |
| SLC38A2 | solute carrier family 38, member 2 | -0.021681 |
| RNF145 | ring finger protein 145 | -0.0215992 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0215765 |
| RPS27 | ribosomal protein S27 | -0.0213944 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0211082 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | -0.0210028 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0206131 |
| RPLP0 | ribosomal protein, large, P0 | -0.0204867 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0204381 |
| RPS21 | ribosomal protein S21 | -0.0203642 |
| TBCA | tubulin folding cofactor A | -0.019941 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0199079 |
| TFG | TRK-fused gene | -0.0198935 |
