| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Crizotinib (hydrochloride) perturbation in NCI-H661 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Crizotinib (hydrochloride)_NCI-H661 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.188723 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.152202 |
| VIM | vimentin | 0.152108 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.141764 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.119874 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0888488 |
| PEG10 | paternally expressed 10 | 0.0821508 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0787631 |
| TMSB4X | thymosin beta 4, X-linked | 0.0774515 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0722147 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0714212 |
| ZNF292 | zinc finger protein 292 | 0.0702316 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0701996 |
| SUPT5H | suppressor of Ty 5 homolog (S. cerevisiae) | 0.068545 |
| ZEB2 | zinc finger E-box binding homeobox 2 | 0.0604624 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0603144 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | 0.0583579 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0555778 |
| TPX2 | TPX2, microtubule-associated | 0.0554353 |
| CENPF | centromere protein F, 350/400kDa | 0.0542714 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0533944 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0521533 |
| HNRNPD | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) | 0.0521468 |
| HDAC9 | histone deacetylase 9 | 0.0514291 |
| ZNF608 | zinc finger protein 608 | 0.0510019 |
| MKI67 | marker of proliferation Ki-67 | 0.0508915 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0503565 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0492834 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0476944 |
| FLNA | filamin A, alpha | 0.0471999 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.0471646 |
| MTF2 | metal response element binding transcription factor 2 | 0.0465306 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0460209 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0443505 |
| RAD21 | RAD21 homolog (S. pombe) | 0.0443169 |
| BAZ1A | bromodomain adjacent to zinc finger domain, 1A | 0.0431302 |
| COL3A1 | collagen, type III, alpha 1 | 0.042477 |
| DST | dystonin | 0.0424082 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0421473 |
| ACTN4 | actinin, alpha 4 | 0.0413276 |
| METAP2 | methionyl aminopeptidase 2 | 0.0411583 |
| CANX | calnexin | 0.0397456 |
| PDGFC | platelet derived growth factor C | 0.0397144 |
| RPS4X | ribosomal protein S4, X-linked | 0.0393564 |
| G2E3 | G2/M-phase specific E3 ubiquitin protein ligase | 0.0380945 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0378457 |
| IGF1R | insulin-like growth factor 1 receptor | 0.0378319 |
| KIF4A | kinesin family member 4A | 0.0377495 |
| CDC73 | cell division cycle 73 | 0.0373096 |
| HMGB2 | high mobility group box 2 | 0.0372473 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.036921 |
| CKAP2 | cytoskeleton associated protein 2 | 0.0368526 |
| RPL7 | ribosomal protein L7 | 0.0365207 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | 0.0364716 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0356615 |
| FIGN | fidgetin | 0.0355465 |
| EMP1 | epithelial membrane protein 1 | 0.035516 |
| MATR3 | matrin 3 | 0.0349568 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0344986 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0336563 |
| HNRNPM | heterogeneous nuclear ribonucleoprotein M | 0.0335587 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.0335136 |
| TPM3 | tropomyosin 3 | 0.0332859 |
| ATP5F1B | ATP synthase F1 subunit beta | 0.0332834 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0330163 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0326477 |
| APP | amyloid beta (A4) precursor protein | 0.0321137 |
| YBX1 | Y box binding protein 1 | 0.0319166 |
| H1-4 | H1.4 linker histone, cluster member | 0.0315858 |
| HNRNPH3 | heterogeneous nuclear ribonucleoprotein H3 (2H9) | 0.0315226 |
| PDIA4 | protein disulfide isomerase family A, member 4 | 0.0312503 |
| DEK | DEK proto-oncogene | 0.0311458 |
| PSMD2 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 2 | 0.0306514 |
| ANP32A | acidic (leucine-rich) nuclear phosphoprotein 32 family, member A | 0.030561 |
| SPAG5 | sperm associated antigen 5 | 0.0303435 |
| ZNF385D | zinc finger protein 385D | 0.0298626 |
| RHEB | Ras homolog enriched in brain | 0.0298307 |
| PUM1 | pumilio RNA-binding family member 1 | 0.0298241 |
| SHROOM3 | shroom family member 3 | 0.0298158 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | 0.0296386 |
| ADGRL2 | adhesion G protein-coupled receptor L2 | 0.0294217 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0293998 |
| CXADR | coxsackie virus and adenovirus receptor | 0.0292704 |
| HYCC1 | hyccin PI4KA lipid kinase complex subunit 1 | 0.0290325 |
| RDX | radixin | 0.0288161 |
| RBM25 | RNA binding motif protein 25 | 0.0287605 |
| BTBD3 | BTB (POZ) domain containing 3 | 0.0285732 |
| SERINC1 | serine incorporator 1 | 0.0285229 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0282814 |
| SYNCRIP | synaptotagmin binding, cytoplasmic RNA interacting protein | 0.027729 |
| CKAP5 | cytoskeleton associated protein 5 | 0.0277222 |
| NCKAP1 | NCK-associated protein 1 | 0.0277197 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0275642 |
| SP3 | Sp3 transcription factor | 0.0273899 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0273042 |
| PCBP2 | poly(rC) binding protein 2 | 0.0272032 |
| YES1 | YES proto-oncogene 1, Src family tyrosine kinase | 0.0271812 |
| SSB | Sjogren syndrome antigen B (autoantigen La) | 0.0271644 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0271087 |
| ANLN | anillin, actin binding protein | 0.0269238 |
| Symbol | Name | Standardized Value |
|---|---|---|
| COL11A1 | collagen, type XI, alpha 1 | -0.160971 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.157393 |
| CDH10 | cadherin 10, type 2 (T2-cadherin) | -0.11428 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.110866 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.103496 |
| ERBB4 | erb-b2 receptor tyrosine kinase 4 | -0.100541 |
| CDH6 | cadherin 6, type 2, K-cadherin (fetal kidney) | -0.0825909 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0751534 |
| PCDH9 | protocadherin 9 | -0.0730977 |
| CTNNA3 | catenin (cadherin-associated protein), alpha 3 | -0.0699354 |
| TMSB10 | thymosin beta 10 | -0.0688474 |
| RAD51B | RAD51 paralog B | -0.0593978 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0593917 |
| NEBL | nebulette | -0.0586828 |
| RPS6 | ribosomal protein S6 | -0.0583288 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0582492 |
| CTNNA2 | catenin (cadherin-associated protein), alpha 2 | -0.0570878 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0550886 |
| PHIP | pleckstrin homology domain interacting protein | -0.0527321 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -0.0520864 |
| RPL35A | ribosomal protein L35a | -0.0517454 |
| BMPR1A | bone morphogenetic protein receptor, type IA | -0.0489844 |
| ENO1 | enolase 1, (alpha) | -0.0484269 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0484107 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0476829 |
| RPS8 | ribosomal protein S8 | -0.0472894 |
| CADM2 | cell adhesion molecule 2 | -0.0464532 |
| LRRC4C | leucine rich repeat containing 4C | -0.0455392 |
| MDK | midkine (neurite growth-promoting factor 2) | -0.0454356 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0448895 |
| ACTG1 | actin gamma 1 | -0.0442564 |
| PCLO | piccolo presynaptic cytomatrix protein | -0.0440137 |
| SNX6 | sorting nexin 6 | -0.0414909 |
| PGK1 | phosphoglycerate kinase 1 | -0.0409283 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0405294 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | -0.0399793 |
| NCAM2 | neural cell adhesion molecule 2 | -0.0398611 |
| RPS16 | ribosomal protein S16 | -0.0385198 |
| MYADM | myeloid-associated differentiation marker | -0.0377691 |
| GALNTL6 | polypeptide N-acetylgalactosaminyltransferase-like 6 | -0.0371974 |
| PGAP1 | post-GPI attachment to proteins 1 | -0.0368787 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0366329 |
| DYNC2H1 | dynein, cytoplasmic 2, heavy chain 1 | -0.0357627 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0356893 |
| COL5A2 | collagen, type V, alpha 2 | -0.0354722 |
| RPL28 | ribosomal protein L28 | -0.0353936 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0351512 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0337111 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0333293 |
| COL1A2 | collagen, type I, alpha 2 | -0.0332284 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | -0.0331394 |
| FTL | ferritin, light polypeptide | -0.033086 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0328144 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0326169 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0325129 |
| RPL9 | ribosomal protein L9 | -0.0323267 |
| ZC3H12B | zinc finger CCCH-type containing 12B | -0.0321628 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0316433 |
| FN1 | fibronectin 1 | -0.031623 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0315433 |
| PARD3B | par-3 family cell polarity regulator beta | -0.0315143 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0314791 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0312847 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.031218 |
| RALGAPA1 | Ral GTPase activating protein, alpha subunit 1 (catalytic) | -0.0309621 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | -0.0309203 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0305464 |
| RPL37 | ribosomal protein L37 | -0.0298284 |
| JMJD1C | jumonji domain containing 1C | -0.0297217 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0296921 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0296783 |
| RIGI | RNA sensor RIG-I | -0.0296412 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0294705 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0287853 |
| NDRG1 | N-myc downstream regulated 1 | -0.028747 |
| BPTF | bromodomain PHD finger transcription factor | -0.0285969 |
| CNRIP1 | cannabinoid receptor interacting protein 1 | -0.0285292 |
| CUX1 | cut-like homeobox 1 | -0.0281213 |
| GARRE1 | granule associated Rac and RHOG effector 1 | -0.0280333 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0277141 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | -0.0276645 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0276382 |
| FLNB | filamin B, beta | -0.0274557 |
| NF1 | neurofibromin 1 | -0.0272992 |
| S100A10 | S100 calcium binding protein A10 | -0.0272917 |
| RPS13 | ribosomal protein S13 | -0.027218 |
| AHNAK | AHNAK nucleoprotein | -0.0271469 |
| KDM4B | lysine (K)-specific demethylase 4B | -0.0268672 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0268177 |
| ATXN2 | ataxin 2 | -0.0266326 |
| SYT1 | synaptotagmin I | -0.0264383 |
| RPL7A | ribosomal protein L7a | -0.0264218 |
| SLC44A5 | solute carrier family 44, member 5 | -0.0264005 |
| GOLGA4 | golgin A4 | -0.0259764 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein | -0.0257097 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | -0.0255302 |
| RNF213 | ring finger protein 213 | -0.0254179 |
| TUT4 | terminal uridylyl transferase 4 | -0.0253468 |
| LMO7 | LIM domain 7 | -0.0253121 |
| KDM2A | lysine (K)-specific demethylase 2A | -0.0252454 |
