| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Crizotinib (hydrochloride) perturbation in Panc 03.27 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Crizotinib (hydrochloride)_Panc 03.27 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| LAMB3 | laminin, beta 3 | 0.230002 |
| KRT18 | keratin 18, type I | 0.177077 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.154785 |
| CANX | calnexin | 0.140064 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.124454 |
| PTMA | prothymosin, alpha | 0.111825 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.102393 |
| TMSB4X | thymosin beta 4, X-linked | 0.1016 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0969777 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0928244 |
| EMP1 | epithelial membrane protein 1 | 0.0907323 |
| KRT17 | keratin 17, type I | 0.0877297 |
| MYO6 | myosin VI | 0.0834187 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0831786 |
| CALR | calreticulin | 0.077458 |
| KRT19 | keratin 19, type I | 0.0770829 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0694887 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0659066 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.064654 |
| EZR | ezrin | 0.0630845 |
| DSPP | dentin sialophosphoprotein | 0.0624946 |
| G0S2 | G0/G1 switch 2 | 0.0623058 |
| SMAD3 | SMAD family member 3 | 0.0622772 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0620356 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0606724 |
| LDHA | lactate dehydrogenase A | 0.0605878 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0582376 |
| RPS3 | ribosomal protein S3 | 0.0580251 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0558444 |
| TACSTD2 | tumor-associated calcium signal transducer 2 | 0.0550271 |
| OGA | O-GlcNAcase | 0.0535157 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.052178 |
| LMO7 | LIM domain 7 | 0.0510869 |
| MYO5B | myosin VB | 0.0457166 |
| FLNA | filamin A, alpha | 0.0446895 |
| PLAUR | plasminogen activator, urokinase receptor | 0.0445788 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0444295 |
| PLEC | plectin | 0.0442447 |
| LAMC2 | laminin, gamma 2 | 0.0438597 |
| HLA-E | major histocompatibility complex, class I, E | 0.0437463 |
| PGK1 | phosphoglycerate kinase 1 | 0.0437344 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0436609 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0435881 |
| RIOK3 | RIO kinase 3 | 0.0428003 |
| AFDN | afadin, adherens junction formation factor | 0.0423908 |
| FMNL2 | formin-like 2 | 0.0423023 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0419842 |
| TMF1 | TATA element modulatory factor 1 | 0.0419197 |
| VEGFA | vascular endothelial growth factor A | 0.041488 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0411768 |
| SQSTM1 | sequestosome 1 | 0.0401281 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0398641 |
| ACTN4 | actinin, alpha 4 | 0.039778 |
| FAM107B | family with sequence similarity 107, member B | 0.0397593 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0396828 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0395269 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0391466 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0391295 |
| ANXA11 | annexin A11 | 0.0388743 |
| ARRDC3 | arrestin domain containing 3 | 0.0388552 |
| UBC | ubiquitin C | 0.0383835 |
| FNDC3B | fibronectin type III domain containing 3B | 0.03801 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0378434 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0373486 |
| APP | amyloid beta (A4) precursor protein | 0.0373374 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0370593 |
| RAB11FIP1 | RAB11 family interacting protein 1 (class I) | 0.0354196 |
| NAV2 | neuron navigator 2 | 0.035306 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | 0.0351995 |
| VIM | vimentin | 0.0346315 |
| RPS4X | ribosomal protein S4, X-linked | 0.0343297 |
| HLA-A | major histocompatibility complex, class I, A | 0.0341812 |
| RPL19 | ribosomal protein L19 | 0.0336638 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.031833 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0314528 |
| FLNB | filamin B, beta | 0.0313389 |
| HMGB2 | high mobility group box 2 | 0.0312845 |
| ARGLU1 | arginine and glutamate rich 1 | 0.0309372 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.03028 |
| CNBP | CCHC-type zinc finger, nucleic acid binding protein | 0.0301106 |
| RAD21 | RAD21 homolog (S. pombe) | 0.0300067 |
| NDRG1 | N-myc downstream regulated 1 | 0.0299068 |
| RPL7 | ribosomal protein L7 | 0.0298632 |
| XPO1 | exportin 1 | 0.0294963 |
| OS9 | osteosarcoma amplified 9, endoplasmic reticulum lectin | 0.0294203 |
| INHBA | inhibin, beta A | 0.029362 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0292519 |
| GOLGA4 | golgin A4 | 0.0291353 |
| SF3B2 | splicing factor 3b, subunit 2, 145kDa | 0.0291144 |
| NACA | nascent polypeptide-associated complex alpha subunit | 0.028723 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.0285656 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0285163 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.0282095 |
| FOXO3 | forkhead box O3 | 0.028154 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0280841 |
| RPL13A | ribosomal protein L13a | 0.0279458 |
| CD9 | CD9 molecule | 0.0278592 |
| PLAU | plasminogen activator, urokinase | 0.0278034 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0277269 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0276343 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.111061 |
| POTEF | POTE ankyrin domain family, member F | -0.0844581 |
| MUC4 | mucin 4, cell surface associated | -0.0554442 |
| EGR1 | early growth response 1 | -0.0526144 |
| HMGA1 | high mobility group AT-hook 1 | -0.0456936 |
| LAMA4 | laminin, alpha 4 | -0.039941 |
| MUC16 | mucin 16, cell surface associated | -0.0353579 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0341029 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | -0.0297456 |
| ACTG1 | actin gamma 1 | -0.029194 |
| OSMR | oncostatin M receptor | -0.0281663 |
| PLSCR1 | phospholipid scramblase 1 | -0.027904 |
| RPL35A | ribosomal protein L35a | -0.0278465 |
| RASAL2 | RAS protein activator like 2 | -0.02752 |
| RAD51B | RAD51 paralog B | -0.0260954 |
| FOSL1 | FOS-like antigen 1 | -0.0259094 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0251667 |
| LY6E | lymphocyte antigen 6 complex, locus E | -0.0248567 |
| VMP1 | vacuole membrane protein 1 | -0.0245471 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0243559 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0236715 |
| TAPBP | TAP binding protein (tapasin) | -0.0231559 |
| MX2 | MX dynamin-like GTPase 2 | -0.0227414 |
| LAMA5 | laminin, alpha 5 | -0.0226178 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0225962 |
| ITGBL1 | integrin, beta-like 1 (with EGF-like repeat domains) | -0.021592 |
| TMEM123 | transmembrane protein 123 | -0.0213783 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.0212327 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | -0.0212323 |
| HMGB1 | high mobility group box 1 | -0.0200225 |
| IFI44L | interferon-induced protein 44-like | -0.0199235 |
| METTL15 | methyltransferase like 15 | -0.0196042 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | -0.0194397 |
| FHIT | fragile histidine triad | -0.0191407 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.019129 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0183804 |
| NFIB | nuclear factor I/B | -0.0177969 |
| ANKRD10 | ankyrin repeat domain 10 | -0.0176003 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0174101 |
| SMYD3 | SET and MYND domain containing 3 | -0.0174065 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | -0.0173151 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0171097 |
| ATF7IP | activating transcription factor 7 interacting protein | -0.0170119 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.0167802 |
| RPS15 | ribosomal protein S15 | -0.0167798 |
| EFNA5 | ephrin-A5 | -0.0167393 |
| DIAPH3 | diaphanous-related formin 3 | -0.0164363 |
| EPSTI1 | epithelial stromal interaction 1 (breast) | -0.0163829 |
| PRRG1 | proline rich Gla (G-carboxyglutamic acid) 1 | -0.0160693 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0160448 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.016026 |
| PARD3 | par-3 family cell polarity regulator | -0.0159978 |
| EHBP1 | EH domain binding protein 1 | -0.0159852 |
| RPL28 | ribosomal protein L28 | -0.0158296 |
| CDKAL1 | CDK5 regulatory subunit associated protein 1-like 1 | -0.0158279 |
| FAM3C | family with sequence similarity 3, member C | -0.0157262 |
| ATN1 | atrophin 1 | -0.015687 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | -0.0156695 |
| LRP1B | low density lipoprotein receptor-related protein 1B | -0.0154634 |
| NF1 | neurofibromin 1 | -0.0150245 |
| FCHSD2 | FCH and double SH3 domains 2 | -0.0150039 |
| IFI44 | interferon-induced protein 44 | -0.0149673 |
| U2SURP | U2 snRNP-associated SURP domain containing | -0.0149659 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0147029 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.0146385 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0145259 |
| TNIK | TRAF2 and NCK interacting kinase | -0.0143679 |
| PFN1 | profilin 1 | -0.0143606 |
| NABP1 | nucleic acid binding protein 1 | -0.0142304 |
| RPS21 | ribosomal protein S21 | -0.014126 |
| ANK3 | ankyrin 3, node of Ranvier (ankyrin G) | -0.0139632 |
| ASPH | aspartate beta-hydroxylase | -0.013963 |
| SGMS2 | sphingomyelin synthase 2 | -0.0139054 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0135214 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0134447 |
| SCLT1 | sodium channel and clathrin linker 1 | -0.0134221 |
| MECOM | MDS1 and EVI1 complex locus | -0.013416 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | -0.0133624 |
| ECT2 | epithelial cell transforming 2 | -0.0133557 |
| TMSB10 | thymosin beta 10 | -0.0133172 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0130024 |
| SPIDR | scaffolding protein involved in DNA repair | -0.0129754 |
| RIGI | RNA sensor RIG-I | -0.0129 |
| RSRC1 | arginine/serine-rich coiled-coil 1 | -0.0128945 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0128904 |
| TXNRD1 | thioredoxin reductase 1 | -0.0127099 |
| TBC1D5 | TBC1 domain family, member 5 | -0.0125064 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.0124997 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0123642 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | -0.0123127 |
| PHF14 | PHD finger protein 14 | -0.0123091 |
| RABGAP1L | RAB GTPase activating protein 1-like | -0.0122899 |
| PTEN | phosphatase and tensin homolog | -0.0122453 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.012211 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0118993 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | -0.0118698 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.0118688 |
| LGALS3BP | lectin, galactoside-binding, soluble, 3 binding protein | -0.0117429 |
| EXOC4 | exocyst complex component 4 | -0.0116601 |
| DLC1 | DLC1 Rho GTPase activating protein | -0.0115889 |
