| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Crizotinib (hydrochloride) perturbation in RPMI-7951 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Crizotinib (hydrochloride)_RPMI-7951 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | 0.417877 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.162593 |
| COL6A1 | collagen, type VI, alpha 1 | 0.119676 |
| NAV2 | neuron navigator 2 | 0.0777754 |
| VEGFA | vascular endothelial growth factor A | 0.076887 |
| STC1 | stanniocalcin 1 | 0.0734015 |
| FN1 | fibronectin 1 | 0.0613611 |
| FLNA | filamin A, alpha | 0.0610649 |
| CD109 | CD109 molecule | 0.0489295 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0488291 |
| MSN | moesin | 0.0484345 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0429519 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0425874 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0425387 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0406836 |
| FMNL2 | formin-like 2 | 0.0401266 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0396922 |
| CEP250 | centrosomal protein 250kDa | 0.0379607 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0360689 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0341063 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0336641 |
| TGM2 | transglutaminase 2 | 0.0305535 |
| HPCAL1 | hippocalcin-like 1 | 0.0297619 |
| NUMA1 | nuclear mitotic apparatus protein 1 | 0.0290621 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0286231 |
| FNIP1 | folliculin interacting protein 1 | 0.0284821 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0282882 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0264286 |
| HLA-A | major histocompatibility complex, class I, A | 0.0261083 |
| PLEC | plectin | 0.0261035 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0253959 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0248298 |
| CLEC11A | C-type lectin domain family 11, member A | 0.0247805 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | 0.0242143 |
| TPM3 | tropomyosin 3 | 0.0239159 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0237337 |
| SETD5 | SET domain containing 5 | 0.0235287 |
| CALR | calreticulin | 0.0234929 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0231097 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0230775 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.0230489 |
| SMAD3 | SMAD family member 3 | 0.0230247 |
| PTPRF | protein tyrosine phosphatase, receptor type, F | 0.0227434 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0226358 |
| ARRDC3 | arrestin domain containing 3 | 0.0226053 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0225987 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0221367 |
| TFPI2 | tissue factor pathway inhibitor 2 | 0.0218148 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0217334 |
| STK10 | serine/threonine kinase 10 | 0.0214617 |
| PPP1R18 | protein phosphatase 1, regulatory subunit 18 | 0.0209686 |
| MKI67 | marker of proliferation Ki-67 | 0.0209429 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0207579 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0206145 |
| HDGF | hepatoma-derived growth factor | 0.0205359 |
| IGFN1 | immunoglobulin-like and fibronectin type III domain containing 1 | 0.0205136 |
| EHBP1L1 | EH domain binding protein 1-like 1 | 0.0205048 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.020165 |
| CTNNBL1 | catenin, beta like 1 | 0.0200813 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0199122 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0196869 |
| SUPT5H | suppressor of Ty 5 homolog (S. cerevisiae) | 0.0195894 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.019387 |
| GOLGA4 | golgin A4 | 0.0193033 |
| IQGAP3 | IQ motif containing GTPase activating protein 3 | 0.0190923 |
| KIRREL1 | kirre like nephrin family adhesion molecule 1 | 0.0190121 |
| OPTN | optineurin | 0.018986 |
| HP1BP3 | heterochromatin protein 1, binding protein 3 | 0.0189252 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | 0.0188881 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0186763 |
| CANX | calnexin | 0.01867 |
| INSIG1 | insulin induced gene 1 | 0.0183476 |
| ABHD17C | abhydrolase domain containing 17C | 0.0179163 |
| SQLE | squalene epoxidase | 0.0178955 |
| RHOA | ras homolog family member A | 0.0178931 |
| DOT1L | DOT1-like histone H3K79 methyltransferase | 0.0178756 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0178621 |
| MYO9B | myosin IXB | 0.017685 |
| DIP2C | DIP2 disco-interacting protein 2 homolog C (Drosophila) | 0.0176036 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0175183 |
| FOSL2 | FOS-like antigen 2 | 0.017347 |
| BOD1L1 | biorientation of chromosomes in cell division 1-like 1 | 0.0173312 |
| TAC4 | tachykinin 4 (hemokinin) | 0.0172303 |
| DLGAP4 | discs, large (Drosophila) homolog-associated protein 4 | 0.0168978 |
| DIDO1 | death inducer-obliterator 1 | 0.0168593 |
| APP | amyloid beta (A4) precursor protein | 0.0165799 |
| CTSL | cathepsin L | 0.0164743 |
| SERINC1 | serine incorporator 1 | 0.0157769 |
| RPS4X | ribosomal protein S4, X-linked | 0.0157422 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0156815 |
| SEC23A | Sec23 homolog A (S. cerevisiae) | 0.0155645 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0155135 |
| CNOT12 | CCR4-NOT transcription complex subunit 12 | 0.0154933 |
| GDI2 | GDP dissociation inhibitor 2 | 0.0154894 |
| RANBP9 | RAN binding protein 9 | 0.0153756 |
| COPA | coatomer protein complex, subunit alpha | 0.0153417 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.0153111 |
| AP2M1 | adaptor-related protein complex 2, mu 1 subunit | 0.0151449 |
| TLN1 | talin 1 | 0.0150497 |
| GANAB | glucosidase, alpha; neutral AB | 0.0150083 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.138725 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.135645 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.132977 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.115823 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.100179 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0999216 |
| CD44 | CD44 molecule (Indian blood group) | -0.0928067 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0916135 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0804935 |
| FRMD4A | FERM domain containing 4A | -0.0743737 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.073112 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0693737 |
| IER3 | immediate early response 3 | -0.0675779 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0663247 |
| ZNF292 | zinc finger protein 292 | -0.0604317 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0597746 |
| H1-0 | H1.0 linker histone | -0.0569115 |
| TPM1 | tropomyosin 1 (alpha) | -0.0564645 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0560365 |
| NRP1 | neuropilin 1 | -0.052231 |
| FHIT | fragile histidine triad | -0.0487404 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0482304 |
| GLIS3 | GLIS family zinc finger 3 | -0.0477458 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0466325 |
| ANXA2 | annexin A2 | -0.0463883 |
| SMC4 | structural maintenance of chromosomes 4 | -0.045187 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0445256 |
| SLIT2 | slit homolog 2 (Drosophila) | -0.0444833 |
| MX2 | MX dynamin-like GTPase 2 | -0.0435448 |
| IFI44L | interferon-induced protein 44-like | -0.0423693 |
| PLSCR1 | phospholipid scramblase 1 | -0.041065 |
| ZEB1 | zinc finger E-box binding homeobox 1 | -0.0409855 |
| SMYD3 | SET and MYND domain containing 3 | -0.0405082 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.040266 |
| THBS1 | thrombospondin 1 | -0.0401313 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.0401189 |
| TMEM178B | transmembrane protein 178B | -0.0399771 |
| SP100 | SP100 nuclear antigen | -0.0395753 |
| MAP4 | microtubule-associated protein 4 | -0.0390551 |
| POTEF | POTE ankyrin domain family, member F | -0.03804 |
| HMGB1 | high mobility group box 1 | -0.0378542 |
| FBXO32 | F-box protein 32 | -0.0369434 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | -0.0365991 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.036292 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0361308 |
| EGR1 | early growth response 1 | -0.0360757 |
| IFI44 | interferon-induced protein 44 | -0.0357418 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0356941 |
| COL1A1 | collagen, type I, alpha 1 | -0.0356643 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0352505 |
| RTN4 | reticulon 4 | -0.0351425 |
| XAF1 | XIAP associated factor 1 | -0.034594 |
| RRBP1 | ribosome binding protein 1 | -0.0344757 |
| FAM20C | family with sequence similarity 20, member C | -0.0342581 |
| SAMD9 | sterile alpha motif domain containing 9 | -0.0330063 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0329477 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0328933 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0323129 |
| BRWD3 | bromodomain and WD repeat domain containing 3 | -0.0322432 |
| PGK1 | phosphoglycerate kinase 1 | -0.0320444 |
| PMP22 | peripheral myelin protein 22 | -0.0319128 |
| EPSTI1 | epithelial stromal interaction 1 (breast) | -0.0316771 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0314452 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.031219 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0310091 |
| RUNX1 | runt-related transcription factor 1 | -0.0309333 |
| NREP | neuronal regeneration related protein | -0.0304223 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | -0.0302904 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | -0.0302023 |
| BBS9 | Bardet-Biedl syndrome 9 | -0.0301403 |
| ENO1 | enolase 1, (alpha) | -0.0299068 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.0297998 |
| COL1A2 | collagen, type I, alpha 2 | -0.0297548 |
| CAVIN1 | caveolae associated protein 1 | -0.0296845 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0291778 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0289268 |
| MX1 | MX dynamin-like GTPase 1 | -0.0288353 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0288275 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0287055 |
| RPLP1 | ribosomal protein, large, P1 | -0.0286074 |
| RPS21 | ribosomal protein S21 | -0.0284554 |
| SEC24D | SEC24 family member D | -0.0282445 |
| RIGI | RNA sensor RIG-I | -0.0281268 |
| RBM39 | RNA binding motif protein 39 | -0.0277304 |
| RNF213 | ring finger protein 213 | -0.0276564 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0276514 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0276492 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0274037 |
| TNNC1 | troponin C type 1 (slow) | -0.0273086 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | -0.0270579 |
| SNAP25 | synaptosomal-associated protein, 25kDa | -0.0270403 |
| RLF | rearranged L-myc fusion | -0.0268631 |
| RAD51B | RAD51 paralog B | -0.0268142 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | -0.0267845 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0267022 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0264334 |
| PTMA | prothymosin, alpha | -0.0263505 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | -0.0262483 |
| EML5 | echinoderm microtubule associated protein like 5 | -0.0262349 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0262061 |
