| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Crizotinib (hydrochloride) perturbation in SNU-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Crizotinib (hydrochloride)_SNU-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.224936 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0869935 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0821276 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0749122 |
| TMSB4X | thymosin beta 4, X-linked | 0.0746425 |
| GOLGA4 | golgin A4 | 0.0711149 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0690359 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.06035 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0599127 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0538528 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0440707 |
| ZNF292 | zinc finger protein 292 | 0.0425696 |
| PYGB | phosphorylase, glycogen; brain | 0.0422539 |
| SQSTM1 | sequestosome 1 | 0.0415508 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.038439 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.0373114 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0370446 |
| TMEM41B | transmembrane protein 41B | 0.0361872 |
| RNF145 | ring finger protein 145 | 0.0355835 |
| ZNF608 | zinc finger protein 608 | 0.0351025 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0342189 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0341325 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0340898 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0339686 |
| CYP51A1 | cytochrome P450, family 51, subfamily A, polypeptide 1 | 0.0334815 |
| PGK1 | phosphoglycerate kinase 1 | 0.0334315 |
| TNRC6B | trinucleotide repeat containing 6B | 0.0334206 |
| PDGFC | platelet derived growth factor C | 0.0329594 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0326019 |
| RBM39 | RNA binding motif protein 39 | 0.0320809 |
| RBM25 | RNA binding motif protein 25 | 0.0319046 |
| HDLBP | high density lipoprotein binding protein | 0.0318222 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.03121 |
| TXNRD1 | thioredoxin reductase 1 | 0.0288845 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0286934 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0285392 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | 0.0281714 |
| NUP58 | nucleoporin 58 | 0.0280743 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0278955 |
| RPL13A | ribosomal protein L13a | 0.0277084 |
| NFIA | nuclear factor I/A | 0.0276431 |
| PCBP2 | poly(rC) binding protein 2 | 0.027553 |
| COPA | coatomer protein complex, subunit alpha | 0.0275161 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0272933 |
| S100A6 | S100 calcium binding protein A6 | 0.0272494 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0269441 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0269301 |
| MATR3 | matrin 3 | 0.0265044 |
| ATF4 | activating transcription factor 4 | 0.0263975 |
| ANK2 | ankyrin 2, neuronal | 0.0262373 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.026039 |
| RPL11 | ribosomal protein L11 | 0.0260276 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0257872 |
| RPL3 | ribosomal protein L3 | 0.0257466 |
| ELOVL5 | ELOVL fatty acid elongase 5 | 0.0254847 |
| PTBP2 | polypyrimidine tract binding protein 2 | 0.0254723 |
| ARL15 | ADP-ribosylation factor-like 15 | 0.0254659 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0252799 |
| PHF3 | PHD finger protein 3 | 0.0252242 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | 0.0250737 |
| SETD5 | SET domain containing 5 | 0.0250513 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0247805 |
| NBAS | neuroblastoma amplified sequence | 0.0247459 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.0247143 |
| RBM26 | RNA binding motif protein 26 | 0.0240999 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | 0.0240171 |
| XPO1 | exportin 1 | 0.0239006 |
| TMEM39A | transmembrane protein 39A | 0.0238252 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.023608 |
| BRWD1 | bromodomain and WD repeat domain containing 1 | 0.0234447 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0233048 |
| RPS4X | ribosomal protein S4, X-linked | 0.0231777 |
| EPRS1 | glutamyl-prolyl-tRNA synthetase 1 | 0.023055 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | 0.0229726 |
| ZMYM2 | zinc finger, MYM-type 2 | 0.0228653 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0228143 |
| TFG | TRK-fused gene | 0.0226111 |
| DDX3Y | DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked | 0.0224866 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 0.0224126 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0223543 |
| PRPF38B | pre-mRNA processing factor 38B | 0.0222475 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0221791 |
| TNRC6A | trinucleotide repeat containing 6A | 0.022038 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0219892 |
| POU2F1 | POU class 2 homeobox 1 | 0.0218804 |
| RPL7 | ribosomal protein L7 | 0.0217439 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0215294 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0214512 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0212978 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | 0.0211999 |
| NCOR1 | nuclear receptor corepressor 1 | 0.0210978 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.0209934 |
| PSAT1 | phosphoserine aminotransferase 1 | 0.0209603 |
| FBLN2 | fibulin 2 | 0.0208378 |
| FNBP4 | formin binding protein 4 | 0.020822 |
| PREPL | prolyl endopeptidase-like | 0.0208171 |
| MON2 | MON2 homolog (S. cerevisiae) | 0.0205451 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.0205232 |
| TMF1 | TATA element modulatory factor 1 | 0.0203967 |
| LUC7L2 | LUC7-like 2 (S. cerevisiae) | 0.0203641 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PDE4B | phosphodiesterase 4B, cAMP-specific | -0.117848 |
| AHNAK | AHNAK nucleoprotein | -0.0999339 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0930208 |
| B3GALT1 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1 | -0.092766 |
| GLI3 | GLI family zinc finger 3 | -0.07068 |
| DIAPH3 | diaphanous-related formin 3 | -0.068218 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0669395 |
| BMP10 | bone morphogenetic protein 10 | -0.0663725 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.0584147 |
| ANXA1 | annexin A1 | -0.0564567 |
| CPED1 | cadherin-like and PC-esterase domain containing 1 | -0.0563012 |
| EVI5 | ecotropic viral integration site 5 | -0.0553583 |
| EZR | ezrin | -0.0521027 |
| PTMA | prothymosin, alpha | -0.0468717 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0461668 |
| MKI67 | marker of proliferation Ki-67 | -0.0444707 |
| NAV2 | neuron navigator 2 | -0.0399143 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0386898 |
| MYOF | myoferlin | -0.0383969 |
| BMP2K | BMP2 inducible kinase | -0.0382798 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0381822 |
| RFC3 | replication factor C (activator 1) 3, 38kDa | -0.0380901 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0375727 |
| TNFRSF11B | tumor necrosis factor receptor superfamily, member 11b | -0.0372612 |
| ZEB1 | zinc finger E-box binding homeobox 1 | -0.0368816 |
| FLNB | filamin B, beta | -0.0360901 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.034125 |
| GLI2 | GLI family zinc finger 2 | -0.0336365 |
| CCND1 | cyclin D1 | -0.0335601 |
| ZNF438 | zinc finger protein 438 | -0.033441 |
| ANLN | anillin, actin binding protein | -0.0326797 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | -0.0311795 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0307755 |
| MYO5C | myosin VC | -0.0293001 |
| EBNA1BP2 | EBNA1 binding protein 2 | -0.0292902 |
| RAD18 | RAD18 E3 ubiquitin protein ligase | -0.029116 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0267563 |
| SCLT1 | sodium channel and clathrin linker 1 | -0.02668 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0260457 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0258845 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0256646 |
| TTC28 | tetratricopeptide repeat domain 28 | -0.0256012 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0255273 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0251338 |
| SP100 | SP100 nuclear antigen | -0.0250975 |
| LOXL3 | lysyl oxidase-like 3 | -0.0245277 |
| ALDH1A2 | aldehyde dehydrogenase 1 family, member A2 | -0.024185 |
| CAMKMT | calmodulin-lysine N-methyltransferase | -0.0241345 |
| TJP1 | tight junction protein 1 | -0.0236104 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0236025 |
| PDE7B | phosphodiesterase 7B | -0.0232759 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0225728 |
| EMP3 | epithelial membrane protein 3 | -0.0224533 |
| TPM4 | tropomyosin 4 | -0.0220988 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0220578 |
| PKM | pyruvate kinase, muscle | -0.0220032 |
| RHOA | ras homolog family member A | -0.0217665 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0216003 |
| CENPF | centromere protein F, 350/400kDa | -0.0215494 |
| GALNT10 | polypeptide N-acetylgalactosaminyltransferase 10 | -0.0212199 |
| CREB5 | cAMP responsive element binding protein 5 | -0.0210719 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -0.0207815 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0207662 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | -0.0205703 |
| ATP9B | ATPase, class II, type 9B | -0.0202561 |
| POTEF | POTE ankyrin domain family, member F | -0.0201351 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0198448 |
| NEBL | nebulette | -0.0198146 |
| PKP4 | plakophilin 4 | -0.0197205 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | -0.0195669 |
| HJURP | Holliday junction recognition protein | -0.0195259 |
| RPL35A | ribosomal protein L35a | -0.0194716 |
| TUBB4B | tubulin, beta 4B class IVb | -0.0194443 |
| ECT2 | epithelial cell transforming 2 | -0.0193814 |
| EGFR | epidermal growth factor receptor | -0.0192923 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | -0.0191783 |
| ATAD2 | ATPase family, AAA domain containing 2 | -0.0190652 |
| RRM2 | ribonucleotide reductase M2 | -0.0185063 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0184571 |
| CAVIN2 | caveolae associated protein 2 | -0.0183151 |
| RAD51B | RAD51 paralog B | -0.0179627 |
| PRG2 | proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) | -0.0178792 |
| GPATCH2L | G patch domain containing 2-like | -0.0178448 |
| CRPPA | CDP-L-ribitol pyrophosphorylase A | -0.0178104 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0172305 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | -0.016822 |
| FER | fer (fps/fes related) tyrosine kinase | -0.01669 |
| CEP112 | centrosomal protein 112kDa | -0.0165916 |
| ROCK2 | Rho-associated, coiled-coil containing protein kinase 2 | -0.0165903 |
| RIGI | RNA sensor RIG-I | -0.0164949 |
| RABGAP1L | RAB GTPase activating protein 1-like | -0.0164331 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | -0.0163894 |
| RPL34 | ribosomal protein L34 | -0.0162246 |
| UNC13A | unc-13 homolog A (C. elegans) | -0.0162172 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0161734 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0160518 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0159848 |
| ADAM32 | ADAM metallopeptidase domain 32 | -0.0158318 |
| NT5C2 | 5'-nucleotidase, cytosolic II | -0.0157953 |
| CUX1 | cut-like homeobox 1 | -0.0156737 |
