| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Crizotinib (hydrochloride) perturbation in SW 1088 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Crizotinib (hydrochloride)_SW 1088 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | 0.103572 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0714854 |
| VIM | vimentin | 0.0644511 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0484062 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0450367 |
| SERINC1 | serine incorporator 1 | 0.0404806 |
| EFNA5 | ephrin-A5 | 0.0395155 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0394134 |
| CALR | calreticulin | 0.0391841 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0389239 |
| RBM25 | RNA binding motif protein 25 | 0.0385799 |
| PDIA4 | protein disulfide isomerase family A, member 4 | 0.0376609 |
| COL4A2 | collagen, type IV, alpha 2 | 0.0376295 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0374209 |
| FLNA | filamin A, alpha | 0.036677 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0362795 |
| CANX | calnexin | 0.0357898 |
| IGF2R | insulin-like growth factor 2 receptor | 0.034499 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | 0.0331741 |
| GSE1 | Gse1 coiled-coil protein | 0.0329974 |
| WDR33 | WD repeat domain 33 | 0.0320903 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0320539 |
| G3BP2 | GTPase activating protein (SH3 domain) binding protein 2 | 0.0319965 |
| TNRC6A | trinucleotide repeat containing 6A | 0.0319172 |
| RPL3 | ribosomal protein L3 | 0.0316823 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0313147 |
| CAPZA2 | capping protein (actin filament) muscle Z-line, alpha 2 | 0.031211 |
| GOLGB1 | golgin B1 | 0.0310159 |
| TANC1 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1 | 0.0295103 |
| EIF2AK3 | eukaryotic translation initiation factor 2-alpha kinase 3 | 0.0294994 |
| DLGAP4 | discs, large (Drosophila) homolog-associated protein 4 | 0.0294975 |
| DDX3Y | DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked | 0.0294034 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0293775 |
| APP | amyloid beta (A4) precursor protein | 0.0290583 |
| COL1A2 | collagen, type I, alpha 2 | 0.0290402 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0290104 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.0289585 |
| SQSTM1 | sequestosome 1 | 0.0288146 |
| RAB10 | RAB10, member RAS oncogene family | 0.0285299 |
| PTBP2 | polypyrimidine tract binding protein 2 | 0.0282708 |
| CLDN12 | claudin 12 | 0.0281986 |
| OGFRL1 | opioid growth factor receptor-like 1 | 0.0281902 |
| LAMB1 | laminin, beta 1 | 0.0280962 |
| ANO6 | anoctamin 6 | 0.0277469 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.027727 |
| CHMP4B | charged multivesicular body protein 4B | 0.0276155 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | 0.0275568 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0274006 |
| VIRMA | vir like m6A methyltransferase associated | 0.0273851 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0266321 |
| WASF2 | WAS protein family, member 2 | 0.0265846 |
| SBNO1 | strawberry notch homolog 1 (Drosophila) | 0.0265784 |
| GANAB | glucosidase, alpha; neutral AB | 0.0265687 |
| COL6A1 | collagen, type VI, alpha 1 | 0.0263819 |
| PAG1 | phosphoprotein membrane anchor with glycosphingolipid microdomains 1 | 0.0262513 |
| CNBP | CCHC-type zinc finger, nucleic acid binding protein | 0.0262335 |
| MMP14 | matrix metallopeptidase 14 (membrane-inserted) | 0.0261039 |
| ATP13A3 | ATPase type 13A3 | 0.0260226 |
| DCAF13 | DDB1 and CUL4 associated factor 13 | 0.0258103 |
| SFTPA2 | surfactant protein A2 | 0.025388 |
| ZNF143 | zinc finger protein 143 | 0.0253099 |
| CNOT8 | CCR4-NOT transcription complex, subunit 8 | 0.0252284 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | 0.0251875 |
| HECTD4 | HECT domain containing E3 ubiquitin protein ligase 4 | 0.0251008 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.024663 |
| RND3 | Rho family GTPase 3 | 0.0245962 |
| CUL4A | cullin 4A | 0.0245457 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0245374 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | 0.024365 |
| ABI1 | abl-interactor 1 | 0.0242125 |
| LSAMP | limbic system-associated membrane protein | 0.0240941 |
| NACA | nascent polypeptide-associated complex alpha subunit | 0.0237296 |
| UHRF2 | ubiquitin-like with PHD and ring finger domains 2, E3 ubiquitin protein ligase | 0.0235812 |
| ATP2C1 | ATPase, Ca++ transporting, type 2C, member 1 | 0.0235292 |
| LITAF | lipopolysaccharide-induced TNF factor | 0.0233782 |
| ZNF451 | zinc finger protein 451 | 0.0233205 |
| FTL | ferritin, light polypeptide | 0.0232585 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0230994 |
| ALK | anaplastic lymphoma receptor tyrosine kinase | 0.0230882 |
| RELCH | RAB11 binding and LisH domain, coiled-coil and HEAT repeat containing | 0.0230631 |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 | 0.0230319 |
| ACVR1 | activin A receptor, type I | 0.0229837 |
| STX18 | syntaxin 18 | 0.0228882 |
| KDM5C | lysine (K)-specific demethylase 5C | 0.0227804 |
| THRAP3 | thyroid hormone receptor associated protein 3 | 0.0227483 |
| TRPS1 | trichorhinophalangeal syndrome I | 0.0225736 |
| ACTR10 | actin-related protein 10 homolog (S. cerevisiae) | 0.0223822 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0222229 |
| ELOF1 | elongation factor 1 homolog (S. cerevisiae) | 0.021875 |
| CLIC4 | chloride intracellular channel 4 | 0.0217863 |
| TP53BP1 | tumor protein p53 binding protein 1 | 0.0216081 |
| TMEM184B | transmembrane protein 184B | 0.0216 |
| MICU1 | mitochondrial calcium uptake 1 | 0.021545 |
| UBQLN1 | ubiquilin 1 | 0.0214702 |
| IGFBP5 | insulin-like growth factor binding protein 5 | 0.0214449 |
| CALCOCO2 | calcium binding and coiled-coil domain 2 | 0.0214436 |
| FRMD4B | FERM domain containing 4B | 0.0213683 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0212236 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0212194 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | 0.0211387 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.188202 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.119881 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.116664 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.114124 |
| HLA-B | major histocompatibility complex, class I, B | -0.112861 |
| MT2A | metallothionein 2A | -0.0923556 |
| ENO1 | enolase 1, (alpha) | -0.0892022 |
| TMSB10 | thymosin beta 10 | -0.0873868 |
| RTN4 | reticulon 4 | -0.085688 |
| NRXN3 | neurexin 3 | -0.0739609 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0731082 |
| TENT5A | terminal nucleotidyltransferase 5A | -0.066903 |
| B2M | beta-2-microglobulin | -0.0600708 |
| LOX | lysyl oxidase | -0.0595452 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0592279 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0561057 |
| COL1A1 | collagen, type I, alpha 1 | -0.0535804 |
| EGR1 | early growth response 1 | -0.0531178 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | -0.0526422 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0525189 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0508835 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0489201 |
| SPAG9 | sperm associated antigen 9 | -0.0485371 |
| EGFR | epidermal growth factor receptor | -0.0468154 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0467118 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0465294 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0460652 |
| CHD9 | chromodomain helicase DNA binding protein 9 | -0.0458818 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0454654 |
| USP34 | ubiquitin specific peptidase 34 | -0.0450968 |
| ZNF395 | zinc finger protein 395 | -0.0445287 |
| CALD1 | caldesmon 1 | -0.0436552 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.041488 |
| HIP1 | huntingtin interacting protein 1 | -0.0405557 |
| TPM1 | tropomyosin 1 (alpha) | -0.0403996 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0402359 |
| POTEF | POTE ankyrin domain family, member F | -0.0399532 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0396983 |
| CDK6 | cyclin-dependent kinase 6 | -0.0395984 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0394449 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0393683 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0386853 |
| HYCC1 | hyccin PI4KA lipid kinase complex subunit 1 | -0.0384649 |
| STC1 | stanniocalcin 1 | -0.03791 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | -0.0375963 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | -0.0372895 |
| ADM | adrenomedullin | -0.0360655 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0358483 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0355354 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0354519 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0351646 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0351465 |
| CALU | calumenin | -0.0347356 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0347151 |
| GLIS3 | GLIS family zinc finger 3 | -0.0346377 |
| IL6 | interleukin 6 | -0.0346334 |
| CADM1 | cell adhesion molecule 1 | -0.034512 |
| PDPK1 | 3-phosphoinositide dependent protein kinase 1 | -0.0343861 |
| RAD51B | RAD51 paralog B | -0.0343131 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | -0.0341652 |
| NAV1 | neuron navigator 1 | -0.0340296 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0334777 |
| ACTG1 | actin gamma 1 | -0.0332188 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0332179 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.032967 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0329072 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0326702 |
| HMGA2 | high mobility group AT-hook 2 | -0.0318096 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0313392 |
| RAI14 | retinoic acid induced 14 | -0.0311471 |
| SYNPO | synaptopodin | -0.0311061 |
| ADAM9 | ADAM metallopeptidase domain 9 | -0.0307405 |
| MEF2A | myocyte enhancer factor 2A | -0.0306161 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0305142 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0301906 |
| PDE10A | phosphodiesterase 10A | -0.0300909 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0295667 |
| EXOC4 | exocyst complex component 4 | -0.0294134 |
| RPL36 | ribosomal protein L36 | -0.0289964 |
| KIF13A | kinesin family member 13A | -0.0289724 |
| ESCO1 | establishment of sister chromatid cohesion N-acetyltransferase 1 | -0.0289073 |
| UBR3 | ubiquitin protein ligase E3 component n-recognin 3 (putative) | -0.0287384 |
| BBX | bobby sox homolog (Drosophila) | -0.0286687 |
| RPS6 | ribosomal protein S6 | -0.028462 |
| QKI | QKI, KH domain containing, RNA binding | -0.0283075 |
| C1D | C1D nuclear receptor corepressor | -0.0282878 |
| BABAM2 | BRISC and BRCA1 A complex member 2 | -0.0282478 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | -0.0281643 |
| ATXN1 | ataxin 1 | -0.0281396 |
| MYOF | myoferlin | -0.0277304 |
| VEGFC | vascular endothelial growth factor C | -0.0273824 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0272657 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0272226 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0272018 |
| FAM3C | family with sequence similarity 3, member C | -0.0271994 |
| KDM6A | lysine (K)-specific demethylase 6A | -0.0269769 |
| MAP1B | microtubule-associated protein 1B | -0.0268795 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | -0.0267527 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | -0.0265663 |
| ARPC5 | actin related protein 2/3 complex, subunit 5, 16kDa | -0.026528 |
