| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Crizotinib (hydrochloride) perturbation in SW 1271 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Crizotinib (hydrochloride)_SW 1271 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0741138 |
| VIM | vimentin | 0.0718776 |
| CANX | calnexin | 0.0547587 |
| PTMA | prothymosin, alpha | 0.0526303 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0522225 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0516905 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.049445 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.045498 |
| MT2A | metallothionein 2A | 0.0443767 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0434107 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0414164 |
| TPX2 | TPX2, microtubule-associated | 0.0412237 |
| CUL3 | cullin 3 | 0.041013 |
| CEP250 | centrosomal protein 250kDa | 0.0406365 |
| MKI67 | marker of proliferation Ki-67 | 0.0403416 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0401839 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0382291 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0375877 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0375857 |
| DIAPH1 | diaphanous-related formin 1 | 0.0358489 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0356493 |
| FLNA | filamin A, alpha | 0.0354001 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0347416 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0342581 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0332306 |
| SEPTIN2 | septin 2 | 0.0322123 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0320398 |
| FN1 | fibronectin 1 | 0.031303 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0310347 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0306984 |
| PKM | pyruvate kinase, muscle | 0.0305931 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0304206 |
| DDX6 | DEAD (Asp-Glu-Ala-Asp) box helicase 6 | 0.0303193 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.029828 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.0296874 |
| NPTN | neuroplastin | 0.0290917 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0289167 |
| SNRNP200 | small nuclear ribonucleoprotein 200kDa (U5) | 0.0281105 |
| HDGF | hepatoma-derived growth factor | 0.0281039 |
| CENPF | centromere protein F, 350/400kDa | 0.0280567 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.0277768 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0277689 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0277576 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0276258 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0269772 |
| ABL1 | ABL proto-oncogene 1, non-receptor tyrosine kinase | 0.0266204 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | 0.0264651 |
| TRA2B | transformer 2 beta homolog (Drosophila) | 0.0263349 |
| RPL26 | ribosomal protein L26 | 0.026083 |
| LDHA | lactate dehydrogenase A | 0.0260455 |
| PNN | pinin, desmosome associated protein | 0.0259337 |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like | 0.0257461 |
| AFF4 | AF4/FMR2 family, member 4 | 0.0254201 |
| FLNB | filamin B, beta | 0.0254129 |
| RPS3 | ribosomal protein S3 | 0.0252634 |
| ZNF292 | zinc finger protein 292 | 0.02518 |
| CALR | calreticulin | 0.0251781 |
| HDLBP | high density lipoprotein binding protein | 0.0250976 |
| CCNB1 | cyclin B1 | 0.0250407 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.024638 |
| RAB3GAP1 | RAB3 GTPase activating protein subunit 1 (catalytic) | 0.0245267 |
| G3BP1 | GTPase activating protein (SH3 domain) binding protein 1 | 0.0244946 |
| NEDD4 | neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase | 0.0243714 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | 0.0242069 |
| MSANTD3 | Myb/SANT-like DNA-binding domain containing 3 | 0.0236876 |
| MAP3K20 | mitogen-activated protein kinase kinase kinase 20 | 0.0236044 |
| SMC1A | structural maintenance of chromosomes 1A | 0.0235639 |
| GPC6 | glypican 6 | 0.0233589 |
| CEP290 | centrosomal protein 290kDa | 0.0232057 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0231432 |
| IRAK2 | interleukin-1 receptor-associated kinase 2 | 0.0231359 |
| CYTH1 | cytohesin 1 | 0.0231268 |
| CASC3 | cancer susceptibility candidate 3 | 0.0230974 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0226289 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0222134 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | 0.0221333 |
| WDFY1 | WD repeat and FYVE domain containing 1 | 0.0221313 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.0219676 |
| MAPK8 | mitogen-activated protein kinase 8 | 0.021438 |
| MATR3 | matrin 3 | 0.0213596 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0211745 |
| CHD3 | chromodomain helicase DNA binding protein 3 | 0.021157 |
| CDK1 | cyclin-dependent kinase 1 | 0.0210732 |
| RPS12 | ribosomal protein S12 | 0.0204284 |
| MED23 | mediator complex subunit 23 | 0.0202901 |
| APP | amyloid beta (A4) precursor protein | 0.0202648 |
| FOXJ3 | forkhead box J3 | 0.0201441 |
| SET | SET nuclear proto-oncogene | 0.0200162 |
| TUBB4B | tubulin, beta 4B class IVb | 0.0199515 |
| PPP1R12B | protein phosphatase 1, regulatory subunit 12B | 0.0198154 |
| NACA | nascent polypeptide-associated complex alpha subunit | 0.0192675 |
| EIF2AK3 | eukaryotic translation initiation factor 2-alpha kinase 3 | 0.0191856 |
| ASXL1 | additional sex combs like transcriptional regulator 1 | 0.0190812 |
| PPP4R4 | protein phosphatase 4, regulatory subunit 4 | 0.0190727 |
| PYGL | phosphorylase, glycogen, liver | 0.0190641 |
| DIAPH3 | diaphanous-related formin 3 | 0.0188321 |
| PMAIP1 | phorbol-12-myristate-13-acetate-induced protein 1 | 0.0188271 |
| PRPF8 | pre-mRNA processing factor 8 | 0.0188043 |
| PCMTD1 | protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 1 | 0.018771 |
| RPL19 | ribosomal protein L19 | 0.0187272 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.262884 |
| HMGA2 | high mobility group AT-hook 2 | -0.0611962 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0610491 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0567566 |
| INTS6 | integrator complex subunit 6 | -0.0516809 |
| ANXA2 | annexin A2 | -0.05131 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | -0.0468343 |
| GNAS | GNAS complex locus | -0.0437779 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0434508 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | -0.0420895 |
| TMSB10 | thymosin beta 10 | -0.0420411 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | -0.0418761 |
| SMYD3 | SET and MYND domain containing 3 | -0.04107 |
| ATM | ATM serine/threonine kinase | -0.0398465 |
| DST | dystonin | -0.039411 |
| CD44 | CD44 molecule (Indian blood group) | -0.0379602 |
| IGF2 | insulin-like growth factor 2 | -0.03689 |
| PRKCA | protein kinase C, alpha | -0.0358846 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0348946 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0348139 |
| PBX3 | pre-B-cell leukemia homeobox 3 | -0.0344883 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | -0.0333163 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0328826 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0319289 |
| NF1 | neurofibromin 1 | -0.0315705 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | -0.0294673 |
| GOLGA4 | golgin A4 | -0.0293074 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0288867 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0287533 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | -0.0281504 |
| PARD3 | par-3 family cell polarity regulator | -0.0279931 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | -0.0278271 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0276928 |
| ANXA1 | annexin A1 | -0.0276865 |
| ZNF207 | zinc finger protein 207 | -0.0276061 |
| POTEF | POTE ankyrin domain family, member F | -0.0272609 |
| RBM39 | RNA binding motif protein 39 | -0.0272566 |
| GPATCH2L | G patch domain containing 2-like | -0.0266668 |
| CWF19L2 | CWF19-like 2, cell cycle control (S. pombe) | -0.0261553 |
| CBFA2T2 | core-binding factor, runt domain, alpha subunit 2; translocated to, 2 | -0.0261499 |
| PTK2 | protein tyrosine kinase 2 | -0.0261488 |
| COL5A1 | collagen, type V, alpha 1 | -0.0261348 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0261099 |
| EGR1 | early growth response 1 | -0.0260413 |
| TRPC4AP | transient receptor potential cation channel, subfamily C, member 4 associated protein | -0.0259164 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.025868 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.025426 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0254153 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0252454 |
| RPS8 | ribosomal protein S8 | -0.024869 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0247776 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | -0.0247205 |
| PCED1B | PC-esterase domain containing 1B | -0.0245926 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0245466 |
| STARD13 | StAR-related lipid transfer (START) domain containing 13 | -0.0245304 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0241504 |
| HDAC9 | histone deacetylase 9 | -0.0240569 |
| IFRD1 | interferon-related developmental regulator 1 | -0.0239996 |
| ZNF638 | zinc finger protein 638 | -0.0236074 |
| RSF1 | remodeling and spacing factor 1 | -0.0234366 |
| RPLP1 | ribosomal protein, large, P1 | -0.0233845 |
| BPTF | bromodomain PHD finger transcription factor | -0.023357 |
| CDKAL1 | CDK5 regulatory subunit associated protein 1-like 1 | -0.0231153 |
| RAD51B | RAD51 paralog B | -0.0228568 |
| DNAAF9 | dynein axonemal assembly factor 9 | -0.0227746 |
| RBM25 | RNA binding motif protein 25 | -0.022001 |
| TAOK1 | TAO kinase 1 | -0.0219131 |
| RORA | RAR-related orphan receptor A | -0.021912 |
| CD2AP | CD2-associated protein | -0.0218146 |
| PFN1 | profilin 1 | -0.0216197 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0215753 |
| NAP1L4 | nucleosome assembly protein 1-like 4 | -0.021478 |
| CBL | Cbl proto-oncogene, E3 ubiquitin protein ligase | -0.0214663 |
| ACTG1 | actin gamma 1 | -0.0212925 |
| CCDC91 | coiled-coil domain containing 91 | -0.0209097 |
| GORASP2 | golgi reassembly stacking protein 2, 55kDa | -0.0206613 |
| CDK12 | cyclin-dependent kinase 12 | -0.0203169 |
| VCL | vinculin | -0.019915 |
| CDK6 | cyclin-dependent kinase 6 | -0.0198975 |
| RUNX1 | runt-related transcription factor 1 | -0.0196708 |
| IDS | iduronate 2-sulfatase | -0.019585 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0195287 |
| RPL31 | ribosomal protein L31 | -0.0195045 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0194608 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0193895 |
| PCNX4 | pecanex 4 | -0.0193048 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0192646 |
| RHEB | Ras homolog enriched in brain | -0.0191916 |
| RPS20 | ribosomal protein S20 | -0.019112 |
| EXOC4 | exocyst complex component 4 | -0.0190044 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.018972 |
| HMGB1 | high mobility group box 1 | -0.0189445 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0188614 |
| QKI | QKI, KH domain containing, RNA binding | -0.0188383 |
| TRMT11 | tRNA methyltransferase 11 homolog (S. cerevisiae) | -0.0188136 |
| YAP1 | Yes-associated protein 1 | -0.0188048 |
| SYNGAP1 | synaptic Ras GTPase activating protein 1 | -0.0187311 |
| OSMR | oncostatin M receptor | -0.0186717 |
| CDH4 | cadherin 4, type 1, R-cadherin (retinal) | -0.0185033 |
| RFX7 | regulatory factor X, 7 | -0.0185019 |
