| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Crizotinib (hydrochloride) perturbation in SW48 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Crizotinib (hydrochloride)_SW48 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.14959 |
| PTMA | prothymosin, alpha | 0.115534 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0981184 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0814029 |
| LAMB3 | laminin, beta 3 | 0.0791576 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.074335 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0707312 |
| ANXA1 | annexin A1 | 0.0557628 |
| RPS4X | ribosomal protein S4, X-linked | 0.0544347 |
| CDPF1 | cysteine-rich, DPF motif domain containing 1 | 0.0516092 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0506706 |
| LDHA | lactate dehydrogenase A | 0.0491427 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0485304 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0472812 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0419153 |
| CANX | calnexin | 0.0419123 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0409837 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0403269 |
| DSPP | dentin sialophosphoprotein | 0.0399222 |
| RPS3 | ribosomal protein S3 | 0.0386318 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0379616 |
| RPL13A | ribosomal protein L13a | 0.0356293 |
| FLNA | filamin A, alpha | 0.0343588 |
| RPL4 | ribosomal protein L4 | 0.0341609 |
| MYO5B | myosin VB | 0.0335962 |
| RSL1D1 | ribosomal L1 domain containing 1 | 0.0320059 |
| DIAPH1 | diaphanous-related formin 1 | 0.0312861 |
| KLF5 | Kruppel-like factor 5 (intestinal) | 0.031185 |
| FAT1 | FAT atypical cadherin 1 | 0.0305531 |
| KRT18 | keratin 18, type I | 0.0303858 |
| RPL3 | ribosomal protein L3 | 0.0303514 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0302357 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0299426 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0289284 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0284597 |
| DDX3X | DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked | 0.0271584 |
| YME1L1 | YME1-like 1 ATPase | 0.0269664 |
| RPL14 | ribosomal protein L14 | 0.0265459 |
| RPL7 | ribosomal protein L7 | 0.0263742 |
| LMO7 | LIM domain 7 | 0.02609 |
| EZR | ezrin | 0.0257767 |
| APP | amyloid beta (A4) precursor protein | 0.0257734 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.0255476 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0254371 |
| RPS12 | ribosomal protein S12 | 0.0254115 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0253756 |
| SF3B2 | splicing factor 3b, subunit 2, 145kDa | 0.0247358 |
| CALR | calreticulin | 0.0245777 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.023997 |
| TM9SF3 | transmembrane 9 superfamily member 3 | 0.0238202 |
| MIDEAS | mitotic deacetylase associated SANT domain protein | 0.0237764 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0228719 |
| NUP58 | nucleoporin 58 | 0.0226232 |
| EIF3E | eukaryotic translation initiation factor 3, subunit E | 0.0224805 |
| MARS1 | methionyl-tRNA synthetase 1 | 0.0223299 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0222127 |
| ANXA11 | annexin A11 | 0.0218599 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0217542 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0217111 |
| ACBD3 | acyl-CoA binding domain containing 3 | 0.021575 |
| LAMC2 | laminin, gamma 2 | 0.0215466 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0214994 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0212049 |
| EIF3D | eukaryotic translation initiation factor 3, subunit D | 0.0210787 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0210372 |
| IER3 | immediate early response 3 | 0.0207817 |
| BTAF1 | BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa | 0.0207807 |
| PRRC2C | proline-rich coiled-coil 2C | 0.020721 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0206971 |
| ZC3H11A | zinc finger CCCH-type containing 11A | 0.0206937 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0202515 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | 0.0202091 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | 0.0199398 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0198229 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.0197359 |
| CTBP2 | C-terminal binding protein 2 | 0.0195448 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0193465 |
| PPP4R3A | protein phosphatase 4 regulatory subunit 3A | 0.0192523 |
| KDM5C | lysine (K)-specific demethylase 5C | 0.0190196 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0189979 |
| MAP4K5 | mitogen-activated protein kinase kinase kinase kinase 5 | 0.0188179 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0184147 |
| HNRNPR | heterogeneous nuclear ribonucleoprotein R | 0.0184133 |
| NARS1 | asparaginyl-tRNA synthetase 1 | 0.0184063 |
| USP3 | ubiquitin specific peptidase 3 | 0.0183605 |
| COPA | coatomer protein complex, subunit alpha | 0.0183063 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0182381 |
| ST14 | suppression of tumorigenicity 14 (colon carcinoma) | 0.0180844 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0177766 |
| TES | testin LIM domain protein | 0.0176621 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.017652 |
| RANBP9 | RAN binding protein 9 | 0.0175957 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0175649 |
| HDLBP | high density lipoprotein binding protein | 0.0175157 |
| CASC3 | cancer susceptibility candidate 3 | 0.0175075 |
| EREG | epiregulin | 0.017499 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.0174672 |
| ACIN1 | apoptotic chromatin condensation inducer 1 | 0.0173981 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0173225 |
| CARS1 | cysteinyl-tRNA synthetase 1 | 0.0173034 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CD36 | CD36 molecule (thrombospondin receptor) | -0.112379 |
| HMGA2 | high mobility group AT-hook 2 | -0.0938101 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.091405 |
| EGR1 | early growth response 1 | -0.085442 |
| ACTG1 | actin gamma 1 | -0.0791619 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0750951 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0648436 |
| RAD51B | RAD51 paralog B | -0.0618883 |
| FHIT | fragile histidine triad | -0.0606834 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0558975 |
| CCSER1 | coiled-coil serine-rich protein 1 | -0.0465859 |
| CENPF | centromere protein F, 350/400kDa | -0.046034 |
| EGFR | epidermal growth factor receptor | -0.0446674 |
| NAALADL2 | N-acetylated alpha-linked acidic dipeptidase-like 2 | -0.0434535 |
| GPHN | gephyrin | -0.0420686 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0412479 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0385082 |
| FERMT1 | fermitin family member 1 | -0.0384301 |
| OXR1 | oxidation resistance 1 | -0.0372361 |
| RPL35A | ribosomal protein L35a | -0.0366062 |
| PHF14 | PHD finger protein 14 | -0.0354174 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.035145 |
| RBM25 | RNA binding motif protein 25 | -0.0349145 |
| ATXN1 | ataxin 1 | -0.0346492 |
| FLOT1 | flotillin 1 | -0.0341429 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0330611 |
| RPS19 | ribosomal protein S19 | -0.0328877 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0323602 |
| SNX9 | sorting nexin 9 | -0.0318616 |
| EHBP1 | EH domain binding protein 1 | -0.0314845 |
| VTI1A | vesicle transport through interaction with t-SNAREs 1A | -0.0312265 |
| CUX1 | cut-like homeobox 1 | -0.0310726 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0308931 |
| ANK3 | ankyrin 3, node of Ranvier (ankyrin G) | -0.0307324 |
| RPLP1 | ribosomal protein, large, P1 | -0.0304498 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.0296036 |
| VMP1 | vacuole membrane protein 1 | -0.02956 |
| EXOC4 | exocyst complex component 4 | -0.0287509 |
| POTEF | POTE ankyrin domain family, member F | -0.0284551 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | -0.0281308 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0281175 |
| S100A10 | S100 calcium binding protein A10 | -0.0279758 |
| RPS15 | ribosomal protein S15 | -0.0276584 |
| NDRG1 | N-myc downstream regulated 1 | -0.0275605 |
| RPLP2 | ribosomal protein, large, P2 | -0.0269646 |
| TBC1D5 | TBC1 domain family, member 5 | -0.0256456 |
| HPGD | hydroxyprostaglandin dehydrogenase 15-(NAD) | -0.0253466 |
| FRAS1 | Fraser extracellular matrix complex subunit 1 | -0.0245323 |
| BMP4 | bone morphogenetic protein 4 | -0.0244395 |
| RPS8 | ribosomal protein S8 | -0.023834 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0229659 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | -0.0227672 |
| ITFG1 | integrin alpha FG-GAP repeat containing 1 | -0.022649 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0224029 |
| CBX3 | chromobox homolog 3 | -0.0219582 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | -0.0213081 |
| BPTF | bromodomain PHD finger transcription factor | -0.0213054 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0211968 |
| CENPE | centromere protein E, 312kDa | -0.0209788 |
| RALGAPA1 | Ral GTPase activating protein, alpha subunit 1 (catalytic) | -0.0209496 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0205189 |
| RPS29 | ribosomal protein S29 | -0.0204632 |
| SMYD3 | SET and MYND domain containing 3 | -0.0204566 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | -0.0201191 |
| RALGPS2 | Ral GEF with PH domain and SH3 binding motif 2 | -0.0198856 |
| PRELID2 | PRELI domain containing 2 | -0.0198775 |
| FOSL1 | FOS-like antigen 1 | -0.0198698 |
| RPL32 | ribosomal protein L32 | -0.019863 |
| BCAS3 | breast carcinoma amplified sequence 3 | -0.0197379 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | -0.0196373 |
| RPL5 | ribosomal protein L5 | -0.0195742 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.0195442 |
| HMGA1 | high mobility group AT-hook 1 | -0.0195005 |
| ITPKC | inositol-trisphosphate 3-kinase C | -0.0194761 |
| ITGA6 | integrin, alpha 6 | -0.0194235 |
| FAM3C | family with sequence similarity 3, member C | -0.0190059 |
| RPS21 | ribosomal protein S21 | -0.0189757 |
| PPP1R9A | protein phosphatase 1, regulatory subunit 9A | -0.0188822 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.018747 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | -0.0185936 |
| DOCK5 | dedicator of cytokinesis 5 | -0.0185151 |
| PARD3B | par-3 family cell polarity regulator beta | -0.0184887 |
| RPS23 | ribosomal protein S23 | -0.0184841 |
| RPL37A | ribosomal protein L37a | -0.0183186 |
| SKAP1 | src kinase associated phosphoprotein 1 | -0.0181605 |
| DIAPH3 | diaphanous-related formin 3 | -0.0181567 |
| NSRP1 | nuclear speckle splicing regulatory protein 1 | -0.018038 |
| MAN1A1 | mannosidase, alpha, class 1A, member 1 | -0.0180217 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0179875 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0179207 |
| RPL31 | ribosomal protein L31 | -0.0177922 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0177316 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.017691 |
| CMSS1 | cms1 ribosomal small subunit homolog (yeast) | -0.0176683 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0176447 |
| MTAP | methylthioadenosine phosphorylase | -0.0175358 |
| SAMD5 | sterile alpha motif domain containing 5 | -0.0174117 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0173848 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0170743 |
| ACBD6 | acyl-CoA binding domain containing 6 | -0.0170204 |
